ibotenic acid has been researched along with Age-Related Memory Disorders in 41 studies
Ibotenic Acid: A neurotoxic isoxazole (similar to KAINIC ACID and MUSCIMOL) found in AMANITA mushrooms. It causes motor depression, ataxia, and changes in mood, perceptions and feelings, and is a potent excitatory amino acid agonist.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study was aimed to explore the effects of ICS II on cognitive dysfunction and apoptotic response induced by excitatory neurotoxin ibotenic acid (IBO) injection in rats." | 3.88 | Icariside II ameliorates ibotenic acid-induced cognitive impairment and apoptotic response via modulation of MAPK pathway in rats. ( Deng, Y; Gao, J; Gong, Q; He, L; Zeng, L, 2018) |
| "We previously demonstrated that tenuifoliside B and 3,6'-disinapoylsucrose in Polygalae Radix, the root of Polygala tenuifolia WILLDENOW, inhibited potassium cyanide (KCN)-induced hypoxia and scopolamine-induced memory impairment in mice." | 3.74 | Cerebral protective and cognition-improving effects of sinapic acid in rodents. ( Aburada, M; Ikarashi, Y; Ikeya, Y; Karakida, F; Takeda, S; Tsunakawa, M; Yamaguchi, T, 2007) |
| "Patients with an orofacial pain history appear to be more susceptible to occlusal interference pain in dental practice for unknown reasons." | 1.43 | Inflammatory pain memory facilitates occlusal interference-induced masticatory muscle hyperalgesia in rats. ( Cao, Y; Ding, TT; Gan, YH; Liu, CR; Xie, QF; Xu, XX, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (7.32) | 18.7374 |
| 1990's | 8 (19.51) | 18.2507 |
| 2000's | 23 (56.10) | 29.6817 |
| 2010's | 7 (17.07) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| He, L | 1 |
| Deng, Y | 1 |
| Gao, J | 1 |
| Zeng, L | 1 |
| Gong, Q | 1 |
| Hong, SW | 1 |
| Heo, H | 1 |
| Yang, JH | 1 |
| Han, M | 1 |
| Kim, DH | 1 |
| Kwon, YK | 1 |
| Ding, TT | 1 |
| Xu, XX | 1 |
| Cao, Y | 1 |
| Liu, CR | 1 |
| Gan, YH | 1 |
| Xie, QF | 1 |
| Kapgal, V | 1 |
| Prem, N | 1 |
| Hegde, P | 1 |
| Laxmi, TR | 2 |
| Kutty, BM | 1 |
| Izaki, Y | 1 |
| Takita, M | 1 |
| Akema, T | 1 |
| Bailey, DJ | 1 |
| Wade, J | 1 |
| Saldanha, CJ | 1 |
| Alvarado, MC | 2 |
| Kazama, A | 1 |
| Zeamer, A | 1 |
| Bachevalier, J | 2 |
| Eckart, MT | 1 |
| Huelse-Matia, MC | 1 |
| Schwarting, RK | 1 |
| Feng, C | 1 |
| Zhang, C | 1 |
| Shao, X | 1 |
| Liu, Q | 1 |
| Qian, Y | 1 |
| Feng, L | 1 |
| Chen, J | 1 |
| Zha, Y | 1 |
| Zhang, Q | 1 |
| Jiang, X | 1 |
| Muir, GM | 1 |
| Bilkey, DK | 3 |
| Malkova, L | 1 |
| Mishkin, M | 1 |
| Need, AC | 1 |
| Irvine, EE | 1 |
| Giese, KP | 1 |
| Liu, P | 2 |
| Jarrard, LE | 2 |
| Lee, I | 1 |
| Kesner, RP | 1 |
| Winters, BD | 1 |
| Forwood, SE | 1 |
| Cowell, RA | 1 |
| Saksida, LM | 1 |
| Bussey, TJ | 1 |
| Li, Y | 1 |
| Qin, HQ | 1 |
| Chen, QS | 1 |
| Wang, JJ | 1 |
| Hu, Y | 1 |
| Xia, Z | 1 |
| Sun, Q | 1 |
| Orsi, A | 1 |
| Rees, D | 1 |
| Marquis, JP | 1 |
| Goulet, S | 1 |
| Doré, FY | 1 |
| Watanabe, S | 1 |
| Nakamura, S | 1 |
| Murayama, N | 1 |
| Noshita, T | 1 |
| Katsuragi, R | 1 |
| Ohno, T | 1 |
| Good, MA | 1 |
| Barnes, P | 1 |
| Staal, V | 1 |
| McGregor, A | 1 |
| Honey, RC | 1 |
| Karakida, F | 1 |
| Ikeya, Y | 1 |
| Tsunakawa, M | 1 |
| Yamaguchi, T | 1 |
| Ikarashi, Y | 1 |
| Takeda, S | 1 |
| Aburada, M | 1 |
| Hruska, Z | 1 |
| Dohanich, GP | 1 |
| Albasser, MM | 1 |
| Poirier, GL | 1 |
| Warburton, EC | 1 |
| Aggleton, JP | 1 |
| Dornan, WA | 1 |
| Kang, DE | 1 |
| McCampbell, A | 1 |
| Kang, EE | 1 |
| Senda, T | 1 |
| Matsuno, K | 1 |
| Okamoto, K | 1 |
| Kobayashi, T | 1 |
| Nakata, K | 1 |
| Mita, S | 1 |
| Bhattacharya, SK | 1 |
| Kumar, A | 1 |
| Cassel, JC | 1 |
| Cassel, S | 1 |
| Galani, R | 1 |
| Kelche, C | 1 |
| Will, B | 1 |
| Jarrard, L | 1 |
| Bindu, PN | 1 |
| Raju, TR | 1 |
| Meti, BL | 1 |
| Beason-Held, LL | 1 |
| Rosene, DL | 1 |
| Killiany, RJ | 1 |
| Moss, MB | 1 |
| Célérier, A | 1 |
| Ognard, R | 1 |
| Decorte, L | 1 |
| Beracochea, D | 1 |
| Gerlai, RT | 1 |
| McNamara, A | 1 |
| Williams, S | 1 |
| Phillips, HS | 1 |
| Chen, Z | 1 |
| Shen, YJ | 1 |
| Xu, XH | 1 |
| Pan, YP | 1 |
| Wang, XL | 1 |
| Moran, PM | 1 |
| LeMaître, MH | 1 |
| Philouze, V | 1 |
| Reymann, JM | 1 |
| Allain, H | 1 |
| Leonard, BE | 1 |
| Hodges, H | 1 |
| Allen, Y | 1 |
| Sinden, J | 1 |
| Lantos, PL | 1 |
| Gray, JA | 1 |
| Ridley, RM | 1 |
| Baker, HF | 1 |
| Murray, TK | 1 |
| Mayo, W | 1 |
| Kharouby, M | 1 |
| Le Moal, M | 1 |
| Simon, H | 1 |
| Hepler, DJ | 1 |
| Olton, DS | 1 |
| Wenk, GL | 1 |
| Coyle, JT | 1 |
41 other studies available for ibotenic acid and Age-Related Memory Disorders
| Article | Year |
|---|---|
Icariside II ameliorates ibotenic acid-induced cognitive impairment and apoptotic response via modulation of MAPK pathway in rats.
Topics: Alzheimer Disease; Animals; Apoptosis; Calbindins; Caspase 3; Cognitive Dysfunction; Down-Regulation | 2018 |
Soyasaponin I improved neuroprotection and regeneration in memory deficient model rats.
Topics: Animals; Behavior, Animal; Biomarkers; Cell Differentiation; Cell Proliferation; Cells, Cultured; Di | 2013 |
Inflammatory pain memory facilitates occlusal interference-induced masticatory muscle hyperalgesia in rats.
Topics: Animals; Carrageenan; Facial Pain; Hyperalgesia; Ibotenic Acid; Inflammation; Male; Masticatory Musc | 2016 |
Long term exposure to combination paradigm of environmental enrichment, physical exercise and diet reverses the spatial memory deficits and restores hippocampal neurogenesis in ventral subicular lesioned rats.
Topics: Animals; Diet; Environment; Hippocampus; Ibotenic Acid; Male; Memory Disorders; Neurogenesis; Physic | 2016 |
Specific role of the posterior dorsal hippocampus-prefrontal cortex in short-term working memory.
Topics: Animals; Conditioning, Operant; Denervation; Dominance, Cerebral; Functional Laterality; Hippocampus | 2008 |
Hippocampal lesions impair spatial memory performance, but not song--a developmental study of independent memory systems in the zebra finch.
Topics: Age Factors; Aging; Animals; Aromatase; Denervation; Estrogens; Female; Finches; Genes, Immediate-Ea | 2009 |
The effects of selective hippocampal damage on tests of oddity in rhesus macaques.
Topics: Animals; Decision Making; Discrimination Learning; Excitatory Amino Acid Agonists; Female; Hippocamp | 2011 |
Dorsal hippocampal lesions boost performance in the rat sequential reaction time task.
Topics: Animals; Excitatory Amino Acid Agonists; Hippocampus; Ibotenic Acid; Magnetic Resonance Imaging; Mal | 2012 |
Enhancement of nose-to-brain delivery of basic fibroblast growth factor for improving rat memory impairments induced by co-injection of β-amyloid and ibotenic acid into the bilateral hippocampus.
Topics: Acetylcholinesterase; Administration, Intranasal; Aerosols; Amyloid beta-Peptides; Animals; Blood-Br | 2012 |
Theta- and movement velocity-related firing of hippocampal neurons is disrupted by lesions centered on the perirhinal cortex.
Topics: Action Potentials; Animals; Hippocampus; Ibotenic Acid; Interneurons; Male; Memory Disorders; Motion | 2003 |
One-trial memory for object-place associations after separate lesions of hippocampus and posterior parahippocampal region in the monkey.
Topics: Animals; Association; Female; Hippocampus; Ibotenic Acid; Macaca mulatta; Male; Memory; Memory Disor | 2003 |
Learning and memory impairments in Kv beta 1.1-null mutants are rescued by environmental enrichment or ageing.
Topics: Aging; Animals; Animals, Newborn; Behavior, Animal; Cues; Disease Models, Animal; Eating; Environmen | 2003 |
Excitotoxic lesions of the pre- and parasubiculum disrupt the place fields of hippocampal pyramidal cells.
Topics: Action Potentials; Animals; Denervation; Hippocampus; Ibotenic Acid; Male; Memory; Memory Disorders; | 2004 |
Differential contributions of dorsal hippocampal subregions to memory acquisition and retrieval in contextual fear-conditioning.
Topics: Animals; Colchicine; Conditioning, Psychological; Denervation; Dentate Gyrus; Fear; Hippocampus; Ibo | 2004 |
Double dissociation between the effects of peri-postrhinal cortex and hippocampal lesions on tests of object recognition and spatial memory: heterogeneity of function within the temporal lobe.
Topics: Animals; Brain Mapping; Exploratory Behavior; Hippocampus; Ibotenic Acid; Male; Maze Learning; Memor | 2004 |
Selective neurotoxic damage to the hippocampal formation impairs performance of the transverse patterning and location memory tasks in rhesus macaques.
Topics: Animals; Denervation; Female; Hippocampus; Ibotenic Acid; Learning; Macaca mulatta; Magnetic Resonan | 2005 |
Behavioral and neurochemical effects of the intrahippocampal co-injection of beta-amyloid protein 1-40 and ibotenic acid in rats.
Topics: Amyloid beta-Peptides; Animals; Avoidance Learning; Disease Models, Animal; Exploratory Behavior; Hi | 2004 |
A new approach to the pharmacological regulation of memory: Sarsasapogenin improves memory by elevating the low muscarinic acetylcholine receptor density in brains of memory-deficit rat models.
Topics: Acetylcholinesterase; Age Factors; Amyloid beta-Peptides; Animals; Autoradiography; Brain; Disease M | 2005 |
Neonatal lesions of the ventral hippocampus in rats lead to prefrontal cognitive deficits at two maturational stages.
Topics: Aging; Animals; Animals, Newborn; Avoidance Learning; Cognition Disorders; Denervation; Disease Mode | 2006 |
Effects of partial hippocampal lesions by ibotenic acid on repeated acquisition of spatial discrimination in pigeons.
Topics: Animals; Columbidae; Denervation; Discrimination Learning; Excitatory Amino Acid Agonists; Hippocamp | 2006 |
Cognitive dysfunction induced by sequential injection of amyloid-beta and ibotenate into the bilateral hippocampus; protection by memantine and MK-801.
Topics: Amyloid beta-Peptides; Animals; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid A | 2006 |
Context- but not familiarity-dependent forms of object recognition are impaired following excitotoxic hippocampal lesions in rats.
Topics: Animals; Brain Injuries; Hippocampus; Ibotenic Acid; Male; Memory Disorders; Mental Recall; Neuropsy | 2007 |
Cerebral protective and cognition-improving effects of sinapic acid in rodents.
Topics: Acetylcholine; Amnesia; Animals; Carbon Dioxide; Cognition; Coma; Coumaric Acids; Dose-Response Rela | 2007 |
The effects of chronic estradiol treatment on working memory deficits induced by combined infusion of beta-amyloid (1-42) and ibotenic acid.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Analysis of Variance; Animals; Disease Models, Animal; Est | 2007 |
Hippocampal lesions halve immediate-early gene protein counts in retrosplenial cortex: distal dysfunctions in a spatial memory system.
Topics: Analysis of Variance; Animals; Behavior, Animal; Catheter Ablation; Cell Count; Excitatory Amino Aci | 2007 |
Bilateral injections of beta A(25-35) + IBO into the hippocampus disrupts acquisition of spatial learning in the rat.
Topics: Amyloid beta-Peptides; Animals; Drug Synergism; Escape Reaction; Exploratory Behavior; Hippocampus; | 1993 |
Ameliorating effect of SA4503, a novel sigma 1 receptor agonist, on memory impairments induced by cholinergic dysfunction in rats.
Topics: Animals; Avoidance Learning; Guinea Pigs; Ibotenic Acid; Male; Memory; Memory Disorders; Nootropic A | 1996 |
Effect of Trasina, an ayurvedic herbal formulation, on experimental models of Alzheimer's disease and central cholinergic markers in rats.
Topics: Acetylcholine; Alzheimer Disease; Animals; Binding Sites; Choline O-Acetyltransferase; Cholinergic A | 1997 |
Fimbria-fornix vs selective hippocampal lesions in rats: effects on locomotor activity and spatial learning and memory.
Topics: Analysis of Variance; Animals; Behavior, Animal; Electrodes, Implanted; Excitatory Amino Acid Agonis | 1998 |
Spatial memory impairment in ventral subicular lesioned rats.
Topics: Animals; Behavior, Animal; Conditioning, Operant; Hippocampus; Ibotenic Acid; Male; Maze Learning; M | 1999 |
Hippocampal formation lesions produce memory impairment in the rhesus monkey.
Topics: Animals; Brain Mapping; Color Perception; Hippocampus; Ibotenic Acid; Learning; Macaca mulatta; Male | 1999 |
Deficits of spatial and non-spatial memory and of auditory fear conditioning following anterior thalamic lesions in mice: comparison with chronic alcohol consumption.
Topics: Acoustic Stimulation; Aging; Alcohol Amnestic Disorder; Alcoholism; Animals; Auditory Cortex; Behavi | 2000 |
Excitotoxic lesions of the pre- and parasubiculum disrupt object recognition and spatial memory processes.
Topics: Animals; Behavior, Animal; Brain; Excitatory Amino Acid Agonists; Hippocampus; Ibotenic Acid; Male; | 2001 |
Hippocampal dysfunction and behavioral deficit in the water maze in mice: an unresolved issue?
Topics: Animals; Behavior, Animal; Brain Injuries; Disease Models, Animal; Excitatory Amino Acid Agonists; F | 2002 |
Effects of brain histamine on memory deficit induced by nucleus basalis-lesion in rats.
Topics: Animals; Avoidance Learning; Basal Ganglia; Histamine; Ibotenic Acid; Injections, Intraventricular; | 2002 |
mRNA expression alterations of inward rectifier potassium channels in rat brain with cholinergic impairment.
Topics: Acetylcholine; Acetylcholinesterase; Alzheimer Disease; Animals; Basal Nucleus of Meynert; Cerebral | 2002 |
Reversal of learning and memory impairments following lesion of the nucleus basalis magnocellularis (NBM) by concurrent noradrenergic depletion using DSP4 in the rat.
Topics: Adrenergic Agents; Animals; Avoidance Learning; Basal Ganglia; Benzylamines; Choline O-Acetyltransfe | 1992 |
Cholinergic-rich transplants alleviate cognitive deficits in lesioned rats, but exacerbate response to cholinergic drugs.
Topics: Animals; Brain Tissue Transplantation; Cerebral Cortex; Cholinergic Fibers; Conditioning, Operant; F | 1990 |
Basal nucleus lesions in monkeys: recognition memory impairment or visual agnosia?
Topics: Aggression; Agonistic Behavior; Animals; Basal Ganglia; Callitrichinae; Cognition; Discrimination, P | 1988 |
Memory disturbances following ibotenic acid injections in the nucleus basalis magnocellularis of the rat.
Topics: Animals; Basal Ganglia; Choline O-Acetyltransferase; Cholinergic Fibers; Discrimination Learning; Ib | 1988 |
Lesions in nucleus basalis magnocellularis and medial septal area of rats produce qualitatively similar memory impairments.
Topics: Animals; Behavior, Animal; Globus Pallidus; Humans; Ibotenic Acid; Male; Memory Disorders; Rats; Rat | 1985 |