Page last updated: 2024-09-05

ibogaine and Substance Withdrawal Syndrome

ibogaine has been researched along with Substance Withdrawal Syndrome in 36 studies

Research

Studies (36)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	9 (25.00)	18.2507
2000's	14 (38.89)	29.6817
2010's	10 (27.78)	24.3611
2020's	3 (8.33)	2.80

Authors

Authors	Studies
Luz, M; Mash, DC	1
Dürsteler, KM; Froelich, K; Köck, P; Lang, U; Walter, M	1
Mash, DC	1
Frampton, CM; Noller, GE; Yazar-Klosinski, B	1
Alper, K; Brown, TK	1
Brown, TK	1
Athanaselis, SA; Dona, A; Evaggelakos, CI; Goutas, N; Papadodima, SA	1
Alper, K; Antonio, T; Bornmann, WG; Childers, SR; Dersch, CM; Eshleman, AJ; Janowsky, A; King, C; Kuehne, M; Reith, ME; Rothman, RB; Simon, ER	1
Asua, I	1
Ameer, B; Howes, JF; Maillet, EL; Mash, DC; Prou, D	1
Cape, G; Crockett, RS; Darpo, B; Devane, J; Friedhoff, L; Glue, P; Harland, S; Howes, J; Hung, CT; Hung, N; Lam, F; Lockhart, M; Tunnicliff, D; Weis, H; Zhou, M	1
Alper, KR; Gill, JR; Stajić, M	1
Ross, S	1
Elisabetsky, E; Leal, MB; Michelin, K; Souza, DO	1
Glick, SD; Maisonneuve, IM; Panchal, V; Taraschenko, OD	1
Sung, CK; Xu, BJ; Zheng, YN	1
Alper, KR; Glick, SD	1
Barilli, A; Danieli, B; Efange, SM; Elisabetsky, E; Leal, MB; Lesma, G; Linck, VM; Martinelli, M; Mash, DC; Passarella, D; Peretto, I; Silvani, A	1
Bateman, C	1
Daley, M; Fuller, BE; McCarty, D; Rieckmann, T; Thomas, CP	1
Alper, KR; Kaplan, CD; Lotsof, HS	1
Benveniste, M; Fossom, LH; Geter-Douglass, B; Layer, RT; Popik, P; Skolnick, P; Witkin, JM	1
Layer, RT; Popik, P; Skolnick, P	1
Cappendijk, SL; Dzoljic, MR; Fekkes, D	1
Glick, SD; Rho, B	1
Alper, KR; Bastiaans, J; Frenken, GM; Lotsof, HS; Luciano, DJ	2
Glick, SD; Maisonneuve, IM; Szumlinski, KK	1
Alper, KR	1
Ervin, FR; Hearn, WL; Kamlet, JD; Kovera, CA; Mash, DC; Pablo, J; Tyndale, R	1
Parker, LA; Siegel, S	1
Burton, P; Kim, JA; McDonald, RV; Parke, LA; Siegel, S	1
Cros, J; Francés, B; Gout, R; Zajac, JM	1
Carlson, JN; Glick, SD; Maisonneuve, IM; Rao, NC; Rossman, K	1
Jaffe, J; Sharpe, L	1
Jaffe, JH; Sharpe, LG	1

Reviews

8 review(s) available for ibogaine and Substance Withdrawal Syndrome

Article	Year
A systematic literature review of clinical trials and therapeutic applications of ibogaine. Journal of substance abuse treatment, 2022, Volume: 138 Topics: Alkaloids; Hallucinogens; Humans; Ibogaine; Observational Studies as Topic; Randomized Controlled Trials as Topic; Retrospective Studies; Substance Withdrawal Syndrome; Substance-Related Disorders	2022
IUPHAR - invited review - Ibogaine - A legacy within the current renaissance of psychedelic therapy. Pharmacological research, 2023, Volume: 190 Topics: Analgesics, Opioid; Animals; Hallucinogens; Humans; Ibogaine; Substance Withdrawal Syndrome; Substance-Related Disorders	2023
Ibogaine in the treatment of substance dependence. Current drug abuse reviews, 2013, Volume: 6, Issue:1 Topics: Animals; Behavior, Addictive; Disease Models, Animal; History, 19th Century; History, 20th Century; Humans; Ibogaine; Substance Withdrawal Syndrome; Substance-Related Disorders	2013
Natural medicines for alcoholism treatment: a review. Drug and alcohol review, 2005, Volume: 24, Issue:6 Topics: Alcoholism; Animals; Asia; Clinical Trials as Topic; Drugs, Chinese Herbal; Ethanol; Flavonols; Herbal Medicine; Humans; Hypericum; Ibogaine; Medicine, Traditional; Phytotherapy; Plant Extracts; Plant Preparations; Protective Agents; Pueraria; Rats; Salvia miltiorrhiza; Substance Withdrawal Syndrome	2005
100 years of ibogaine: neurochemical and pharmacological actions of a putative anti-addictive drug. Pharmacological reviews, 1995, Volume: 47, Issue:2 Topics: Animals; Calcium; Hallucinogens; Humans; Ibogaine; Neurotoxins; Receptors, GABA; Receptors, Glutamate; Receptors, Opioid; Serotonin; Substance Withdrawal Syndrome; Substance-Related Disorders; Synaptic Transmission	1995
Ibogaine: a review. The Alkaloids. Chemistry and biology, 2001, Volume: 56 Topics: Animals; Brain; Dopamine; Electroencephalography; Hemodynamics; Humans; Ibogaine; Learning; Memory; Neurotransmitter Agents; Self Administration; Substance Withdrawal Syndrome	2001
Ibogaine in the treatment of heroin withdrawal. The Alkaloids. Chemistry and biology, 2001, Volume: 56 Topics: Animals; Heroin Dependence; Humans; Ibogaine; Polymorphism, Genetic; Substance Withdrawal Syndrome	2001
Modulation of the effects of rewarding drugs by ibogaine. The Alkaloids. Chemistry and biology, 2001, Volume: 56 Topics: Animals; Drug Synergism; Humans; Ibogaine; Learning; Morphine; Reward; Substance Withdrawal Syndrome; Substance-Related Disorders	2001

Trials

2 trial(s) available for ibogaine and Substance Withdrawal Syndrome

Article	Year
Ascending Single-Dose, Double-Blind, Placebo-Controlled Safety Study of Noribogaine in Opioid-Dependent Patients. Clinical pharmacology in drug development, 2016, Volume: 5, Issue:6 Topics: Adult; Area Under Curve; Dose-Response Relationship, Drug; Double-Blind Method; Electrocardiography; Female; Heart Rate; Humans; Ibogaine; Long QT Syndrome; Male; Methadone; Narcotics; Opiate Substitution Treatment; Opioid-Related Disorders; Substance Withdrawal Syndrome	2016
Treatment of acute opioid withdrawal with ibogaine. The American journal on addictions, 1999,Summer, Volume: 8, Issue:3 Topics: Adult; Female; Hallucinogens; Heroin Dependence; Humans; Ibogaine; Injections, Intravenous; Male; Substance Withdrawal Syndrome; Treatment Outcome	1999

Article

Year

Ascending Single-Dose, Double-Blind, Placebo-Controlled Safety Study of Noribogaine in Opioid-Dependent Patients.

Clinical pharmacology in drug development, 2016, Volume: 5, Issue:6

Topics: Adult; Area Under Curve; Dose-Response Relationship, Drug; Double-Blind Method; Electrocardiography; Female; Heart Rate; Humans; Ibogaine; Long QT Syndrome; Male; Methadone; Narcotics; Opiate Substitution Treatment; Opioid-Related Disorders; Substance Withdrawal Syndrome

2016

Treatment of acute opioid withdrawal with ibogaine.

The American journal on addictions, 1999,Summer, Volume: 8, Issue:3

Topics: Adult; Female; Hallucinogens; Heroin Dependence; Humans; Ibogaine; Injections, Intravenous; Male; Substance Withdrawal Syndrome; Treatment Outcome

1999

Other Studies

26 other study(ies) available for ibogaine and Substance Withdrawal Syndrome

Article	Year
Reply to Knuijver et al. on the 'Safety of ibogaine administration in detoxification of opioid-dependent individuals: a descriptive open-label observational study'. Addiction (Abingdon, England), 2022, Volume: 117, Issue:3 Topics: Analgesics, Opioid; Humans; Ibogaine; Opioid-Related Disorders; Substance Withdrawal Syndrome	2022
Ibogaine treatment outcomes for opioid dependence from a twelve-month follow-up observational study. The American journal of drug and alcohol abuse, 2018, Volume: 44, Issue:1 Topics: Adult; Depression; Female; Follow-Up Studies; Hallucinogens; Humans; Ibogaine; Male; Middle Aged; Opioid-Related Disorders; Substance Withdrawal Syndrome; Treatment Outcome	2018
Treatment of opioid use disorder with ibogaine: detoxification and drug use outcomes. The American journal of drug and alcohol abuse, 2018, Volume: 44, Issue:1 Topics: Adult; Female; Hallucinogens; Humans; Ibogaine; Male; Opioid-Related Disorders; Substance Withdrawal Syndrome; Treatment Outcome; Young Adult	2018
Ibogaine related sudden death: a case report. Journal of forensic and legal medicine, 2013, Volume: 20, Issue:7 Topics: Alcoholism; Coronary Artery Disease; Death, Sudden, Cardiac; Excitatory Amino Acid Antagonists; Fatty Liver, Alcoholic; Humans; Ibogaine; Liver Cirrhosis; Male; Middle Aged; Substance Withdrawal Syndrome	2013
Effect of Iboga alkaloids on µ-opioid receptor-coupled G protein activation. PloS one, 2013, Volume: 8, Issue:10 Topics: Animals; Autoradiography; Bridged-Ring Compounds; CHO Cells; Cricetulus; Dose-Response Relationship, Drug; Female; Gene Expression; Guanosine 5'-O-(3-Thiotriphosphate); HEK293 Cells; Humans; Ibogaine; Organ Specificity; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Substance Withdrawal Syndrome; Thalamus	2013
Growing menace of ibogaine toxicity. British journal of anaesthesia, 2013, Volume: 111, Issue:6 Topics: Arrhythmias, Cardiac; Excitatory Amino Acid Antagonists; Heroin; Humans; Ibogaine; Male; Narcotics; Self Medication; Substance Withdrawal Syndrome; Young Adult	2013
Oral noribogaine shows high brain uptake and anti-withdrawal effects not associated with place preference in rodents. Journal of psychopharmacology (Oxford, England), 2016, Volume: 30, Issue:7 Topics: Administration, Oral; Animals; Brain; Dose-Response Relationship, Drug; Ibogaine; Male; Mice; Morphine; Naloxone; Rats; Rats, Sprague-Dawley; Retrospective Studies; Rodentia; Substance Withdrawal Syndrome	2016
Fatalities temporally associated with the ingestion of ibogaine. Journal of forensic sciences, 2012, Volume: 57, Issue:2 Topics: Adult; Brain Neoplasms; Cardiovascular Diseases; Female; Forensic Toxicology; Hallucinogens; Humans; Ibogaine; Liver Diseases; Male; Middle Aged; Obesity; Peptic Ulcer; Risk Factors; Seizures; Substance Withdrawal Syndrome; Substance-Related Disorders; Young Adult	2012
Serotonergic hallucinogens and emerging targets for addiction pharmacotherapies. The Psychiatric clinics of North America, 2012, Volume: 35, Issue:2 Topics: Adult; Animals; Behavior, Addictive; Clinical Trials as Topic; Cognition; Dopamine; Dopamine Agonists; Glutamates; Hallucinogens; Humans; Ibogaine; Lysergic Acid; Neuronal Plasticity; Nucleus Accumbens; Phytotherapy; Prefrontal Cortex; Psilocybin; Religion; Reward; Serotonin 5-HT2 Receptor Agonists; Substance Withdrawal Syndrome; Substance-Related Disorders	2012
Ibogaine attenuation of morphine withdrawal in mice: role of glutamate N-methyl-D-aspartate receptors. Progress in neuro-psychopharmacology & biological psychiatry, 2003, Volume: 27, Issue:5 Topics: Animals; Cerebral Cortex; Dizocilpine Maleate; Ibogaine; Male; Mice; Morphine; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome	2003
Attenuation of morphine withdrawal signs by intracerebral administration of 18-methoxycoronaridine. European journal of pharmacology, 2005, Nov-21, Volume: 525, Issue:1-3 Topics: Animals; Brain; Drug Administration Routes; Female; Ibogaine; Locus Coeruleus; Morphine; Morphine Dependence; Naltrexone; Narcotic Antagonists; Narcotics; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome	2005
Psychotropic complementary medicines. The British journal of psychiatry : the journal of mental science, 2006, Volume: 188 Topics: Humans; Ibogaine; Opioid-Related Disorders; Phytotherapy; Plant Extracts; Substance Withdrawal Syndrome	2006
Nature-inspired indolyl-2-azabicyclo[2.2.2]oct-7-ene derivatives as promising agents for the attenuation of withdrawal symptoms: synthesis of 20-desethyl-20-hydroxymethyl-11-demethoxyibogaine. Natural product research, 2006, Jul-10, Volume: 20, Issue:8 Topics: Animals; Ibogaine; Male; Mice; Molecular Structure; Substance Withdrawal Syndrome	2006
Ibogaine may help drug addicts live the 'never again'. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2006, Volume: 96, Issue:7 Topics: Clinical Trials as Topic; Excitatory Amino Acid Antagonists; Humans; Ibogaine; South Africa; Substance Withdrawal Syndrome; Substance-Related Disorders	2006
Client and counselor attitudes toward the use of medications for treatment of opioid dependence. Journal of substance abuse treatment, 2007, Volume: 32, Issue:2 Topics: Adult; Ambulatory Care; Attitude of Health Personnel; Buprenorphine; Clonidine; Counseling; Culture; Female; Focus Groups; Heroin Dependence; Humans; Ibogaine; Male; Methadone; Middle Aged; Narcotics; Opioid-Related Disorders; Patient Admission; Patient Satisfaction; Peer Group; Psychotropic Drugs; Substance Withdrawal Syndrome; Treatment Outcome	2007
The ibogaine medical subculture. Journal of ethnopharmacology, 2008, Jan-04, Volume: 115, Issue:1 Topics: Data Collection; Hallucinogens; Humans; Ibogaine; Internet; Medicine, African Traditional; Opioid-Related Disorders; Substance Withdrawal Syndrome; Substance-Related Disorders	2008
NMDA antagonist properties of the putative antiaddictive drug, ibogaine. The Journal of pharmacology and experimental therapeutics, 1995, Volume: 275, Issue:2 Topics: Animals; Cerebellum; Dizocilpine Maleate; Electric Conductivity; Excitatory Amino Acid Antagonists; Hippocampus; Ibogaine; Male; Mice; Naloxone; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome; Substance-Related Disorders	1995
The inhibitory effect of norharman on morphine withdrawal syndrome in rats: comparison with ibogaine. Behavioural brain research, 1994, Nov-16, Volume: 65, Issue:1 Topics: Animals; Arousal; Brain; Carbolines; Harmine; Ibogaine; Male; Morphine; Naloxone; Rats; Rats, Wistar; Receptors, Opioid; Substance Withdrawal Syndrome	1994
Effects of 18-methoxycoronaridine on acute signs of morphine withdrawal in rats. Neuroreport, 1998, May-11, Volume: 9, Issue:7 Topics: Analysis of Variance; Animals; Female; Hallucinogens; Humans; Ibogaine; Morphine Dependence; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Substance Withdrawal Syndrome; Weight Loss	1998
Ibogaine in acute opioid withdrawal. An open label case series. Annals of the New York Academy of Sciences, 2000, Volume: 909 Topics: Acute Disease; Female; Heroin Dependence; Humans; Ibogaine; Male; Substance Withdrawal Syndrome	2000
18-Methoxycoronaridine (18-MC) and ibogaine: comparison of antiaddictive efficacy, toxicity, and mechanisms of action. Annals of the New York Academy of Sciences, 2000, Volume: 914 Topics: Animals; Behavior, Animal; Cocaine; Dose-Response Relationship, Drug; Drug Interactions; Humans; Ibogaine; In Vitro Techniques; Morphine; Psychopharmacology; Self Administration; Substance Withdrawal Syndrome	2000
Ibogaine interferes with motivational and somatic effects of naloxone-precipitated withdrawal from acutely administered morphine. Progress in neuro-psychopharmacology & biological psychiatry, 2002, Volume: 26, Issue:2 Topics: Animals; Conditioning, Psychological; Drug Administration Schedule; Excitatory Amino Acid Antagonists; Ibogaine; Male; Morphine; Motivation; Naloxone; Narcotic Antagonists; Narcotics; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome	2002
Effects of ibogaine on naloxone-precipitated withdrawal in morphine-dependent mice. Fundamental & clinical pharmacology, 1992, Volume: 6, Issue:8-9 Topics: Animals; Drug Synergism; Ibogaine; Mice; Morphine; Morphine Dependence; Naloxone; Pain Measurement; Substance Withdrawal Syndrome	1992
Effects of ibogaine on acute signs of morphine withdrawal in rats: independence from tremor. Neuropharmacology, 1992, Volume: 31, Issue:5 Topics: Acute Disease; Animals; Ibogaine; Male; Morphine; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Tremor	1992
Ibogaine fails to reduce naloxone-precipitated withdrawal in the morphine dependent rat. NIDA research monograph, 1990, Volume: 105 Topics: Animals; Ibogaine; Morphine Dependence; Naloxone; Rats; Substance Withdrawal Syndrome	1990
Ibogaine fails to reduce naloxone-precipitated withdrawal in the morphine-dependent rat. Neuroreport, 1990, Volume: 1, Issue:1 Topics: Animals; Behavior, Animal; Grooming; Ibogaine; Male; Morphine Dependence; Naloxone; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Tremor	1990