Page last updated: 2024-09-05

ibogaine and Chemical Dependence

ibogaine has been researched along with Chemical Dependence in 75 studies

Research

Studies (75)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	21 (28.00)	18.2507
2000's	25 (33.33)	29.6817
2010's	23 (30.67)	24.3611
2020's	6 (8.00)	2.80

Authors

Authors	Studies
Dürsteler, KM; Froelich, K; Köck, P; Lang, U; Walter, M	1
Canessa, C; Chiappini, S; Corkery, JM; Di Carlo, F; Di Giannantonio, M; Mancusi, G; Martinotti, G; Miuli, A; Mosca, A; Pettorruso, M; Santovito, MC	1
Kremiller, KM; Riley, AP; Rusali, LE; Straub, CJ	1
Alcázar-Córcoles, MÁ; Bouso, JC; Dos Santos, RG; Hallak, JEC; Kohek, M; Ona, G; Rodríguez-Cano, BJ	1
Mash, DC	1
Corne, R; Mongeau, R	1
Anderson, EI; Brown, BM; Cameron, LP; Dunlap, LE; Ehinger, Y; Fiehn, O; Hurley, ZQ; Kokel, D; Laskowski, LJ; Lein, PJ; Liu, T; Lu, J; McCarroll, MN; McCorvy, JD; Myers-Turnbull, D; Olson, DE; Pell, AJ; Peters, J; Rabow, ZT; Ron, D; Taylor, JC; Tjia, M; Tombari, RJ; Vargas, MV; Viswanathan, J; Wulff, H; Yaghoobi, B; Zhang, G; Zuo, Y	1
Surratt, CK; Wasko, MJ; Witt-Enderby, PA	1
Corkery, JM	1
Jávega-Manjón, C; Livianos-Aldana, L; Matamoros-Castillo, JM; Pino-Pino, A; Sierra-San Miguel, P	1
Brown, TK	1
Chaves, BR; da Silveira, DX; de Castro Comis, MA; Schenberg, EE	1
Winkelman, M	1
Hilber, K; Koenig, X	1
Koek, RJ; Kopelowicz, A; Marta, CJ; Ryan, WC	1
Willyard, C	1
Fishback, J; Garamszegi, N; Heghinian, MD; Maillet, EL; Mash, DC; Milon, N; Schürer, SC	1
Brys, Z; Frecska, E; Kazai, A; Szabó, A	1
Boehm, S; Eckert, D; Hilber, K; Koenig, X; Rubi, L	1
Belgers, M; Homberg, JR; Hooijmans, CR; Leenaars, M; Ritskes-Hoitinga, M; Schellekens, AF	1
Galea, S; Newcombe, D; Schep, LJ; Slaughter, RJ	1
Kuszczak, B; Olszak, N; Zdrojewicz, Z	1
Nestor, J	1
Bressolle, FM; Briedis, V; Kontrimaviciute, V; Maciulaitis, R	1
Hoelen, DW; Spiering, W; Valk, GD	1
Galea, S; Lorusso, M; Newcombe, D; Walters, C; Wheeler, A; Williman, J	1
Donnelly, JR	1
Alper, KR; Gill, JR; Stajić, M	1
Ross, S	1
Blagojević, D; Danevčič, T; Jamnik, P; Koželj, G; Krašovec, R; Krstić-Milošević, D; Paškulin, R; Strukelj, B	1
Andrews, LM; Blom, HJ; Paling, FP; Valk, GD	1
Vastag, B	2
Bidlack, JM; Fleck, MW; Glick, SD; He, L; Jokiel, PA; Kuehne, ME; Maisonneuve, IM; Pace, CJ	1
Kazlauskas, S; Kontrimaviciūte, V; Sveikata, A	1
Hittner, JB; Quello, SB	1
Janak, PH; Ron, D	1
Maas, U; Strubelt, S	1
Bateman, C	1
Alper, KR; Kaplan, CD; Lotsof, HS	1
Benveniste, M; Fossom, LH; Geter-Douglass, B; Layer, RT; Popik, P; Skolnick, P; Witkin, JM	1
Layer, RT; Popik, P; Skolnick, P	1
Bauer, C; Collins, JL; Ferkany, J; Lancaster, J; Perschke, S; Snowman, A; Sweetnam, PM	1
Carlson, JN; Glick, SD; Keller, RW; Kuehne, ME; Larson, D; Raucci, J; Wilson, TE	1
Hashim, A; Lajtha, A; Sershen, H	3
Cappendijk, SL; Dzoljic, MR	1
Cai, J; Glick, SD; Maisonneuve, IM; Pearl, SM	1
Popik, P	1
Helsley, S; Rabin, RA; Winter, JC	1
Glick, SD; Maisonneuve, IM; Pearl, SM	1
London, ED; Vocci, FJ	1
Blackburn, JR; Szumlinski, KK	1
Luciano, D	1
Birmingham, K	1
Glick, SD; Maisonneuve, IS	1
Buck, BE; Hearn, WL; Kovera, CA; Mash, DC; Norenberg, MD; Sanchez-Ramos, J; Shapshak, P	1
Morris, K	1
Koerner, BI	1
Bagal, AA; Glick, SD; Hough, LB	1
Glick, SD; Maisonneuve, IM	1
Glick, SD; Maisonneuve, IM; Szumlinski, KK	1
Ervin, FD; Kovera, CA; Mash, DC; Mayor, M; Pablo, J; Singleton, EG; Tyndale, RF; Williams, IC	1
Shoaib, M; Stolerman, IP; Zubaran, C	1
Akinshola, BE; Ali, SF; Onaivi, ES	1
Parker, LA; Siegel, S	1
Alper, KR; Beal, D; Kaplan, CD	1
Frenken, G	1
Alexander, NE; Lotsof, HS	1
Skolnick, P	1
Jenks, CW	1
Akinshola, BE; Ali, SF; Chirwa, SS; Ishiguro, H; Onaivi, ES; Thiriet, N; Zwiller, J	1

Reviews

31 review(s) available for ibogaine and Chemical Dependence

Article	Year
A systematic literature review of clinical trials and therapeutic applications of ibogaine. Journal of substance abuse treatment, 2022, Volume: 138 Topics: Alkaloids; Hallucinogens; Humans; Ibogaine; Observational Studies as Topic; Randomized Controlled Trials as Topic; Retrospective Studies; Substance Withdrawal Syndrome; Substance-Related Disorders	2022
Ibogaine/Noribogaine in the Treatment of Substance Use Disorders: A Systematic Review of the Current Literature. Current neuropharmacology, 2023, Volume: 21, Issue:11 Topics: Humans; Ibogaine; Substance-Related Disorders	2023
What We Have Gained from Ibogaine: α3β4 Nicotinic Acetylcholine Receptor Inhibitors as Treatments for Substance Use Disorders. Journal of medicinal chemistry, 2023, 01-12, Volume: 66, Issue:1 Topics: Dose-Response Relationship, Drug; Humans; Ibogaine; Receptors, Nicotinic; Substance-Related Disorders	2023
IUPHAR - invited review - Ibogaine - A legacy within the current renaissance of psychedelic therapy. Pharmacological research, 2023, Volume: 190 Topics: Analgesics, Opioid; Animals; Hallucinogens; Humans; Ibogaine; Substance Withdrawal Syndrome; Substance-Related Disorders	2023
[Neurotrophic mechanisms of psychedelic therapy]. Biologie aujourd'hui, 2019, Volume: 213, Issue:3-4 Topics: Animals; Hallucinogens; Humans; Ibogaine; Ketamine; Mental Disorders; Nerve Growth Factors; Psychiatry; Serotonin; Serotonin Agents; Substance-Related Disorders	2019
DARK Classics in Chemical Neuroscience: Ibogaine. ACS chemical neuroscience, 2018, 10-17, Volume: 9, Issue:10 Topics: Cardiotoxicity; Hallucinogens; History, 20th Century; History, 21st Century; Humans; Ibogaine; Receptors, Nicotinic; Structure-Activity Relationship; Substance-Related Disorders; Tabernaemontana	2018
Ibogaine as a treatment for substance misuse: Potential benefits and practical dangers. Progress in brain research, 2018, Volume: 242 Topics: Clinical Trials as Topic; Female; Hallucinogens; Humans; Ibogaine; Male; Substance-Related Disorders; United Kingdom	2018
The paradox of iboga: intoxication by a natural detoxification remedy. Actas espanolas de psiquiatria, 2019, Volume: 47, Issue:2 Topics: Adult; Behavioral Symptoms; Confusion; Humans; Ibogaine; Male; Plant Extracts; Substance-Related Disorders; Tabernaemontana	2019
Ibogaine in the treatment of substance dependence. Current drug abuse reviews, 2013, Volume: 6, Issue:1 Topics: Animals; Behavior, Addictive; Disease Models, Animal; History, 19th Century; History, 20th Century; Humans; Ibogaine; Substance Withdrawal Syndrome; Substance-Related Disorders	2013
Psychedelics as medicines for substance abuse rehabilitation: evaluating treatments with LSD, Peyote, Ibogaine and Ayahuasca. Current drug abuse reviews, 2014, Volume: 7, Issue:2 Topics: Animals; Banisteriopsis; Hallucinogens; Humans; Ibogaine; Lysergic Acid Diethylamide; Medicine, Traditional; Mescaline; Serotonin; Substance-Related Disorders	2014
The anti-addiction drug ibogaine and the heart: a delicate relation. Molecules (Basel, Switzerland), 2015, Jan-29, Volume: 20, Issue:2 Topics: Animals; Calcium Channel Blockers; Hallucinogens; Heart Conduction System; Heart Rate; Humans; Ibogaine; Long QT Syndrome; Risk Factors; Substance-Related Disorders	2015
Mania following use of ibogaine: A case series. The American journal on addictions, 2015, Volume: 24, Issue:3 Topics: Adult; Bipolar Disorder; Developing Countries; Female; Hallucinogens; Humans; Ibogaine; Male; Risk Factors; Self Medication; Substance-Related Disorders	2015
[Psychedelics and quasi-psychedelics in the light of contemporary research: medical cannabis, MDMA, salvinorin A, ibogaine and ayahuasca]. Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology, 2015, Volume: 17, Issue:3 Topics: Banisteriopsis; Controlled Substances; Diterpenes, Clerodane; Hallucinogens; Humans; Hungary; Ibogaine; Medical Marijuana; N-Methyl-3,4-methylenedioxyamphetamine; Phytotherapy; Salvia; Substance-Related Disorders	2015
Ibogaine and addiction in the animal model, a systematic review and meta-analysis. Translational psychiatry, 2016, 05-31, Volume: 6, Issue:5 Topics: Animals; Cerebellum; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Ibogaine; Illicit Drugs; Male; Motor Activity; Neurons; Self Administration; Substance-Related Disorders	2016
Ibogaine for treating drug dependence. What is a safe dose? Drug and alcohol dependence, 2016, Sep-01, Volume: 166 Topics: Animals; Arrhythmias, Cardiac; Dose-Response Relationship, Drug; Hallucinogens; Humans; Ibogaine; Substance-Related Disorders; Treatment Outcome	2016
[Ibogaine - structure, influence on human body, clinical relevance]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2016, Jul-29, Volume: 41, Issue:241 Topics: Cardiotoxicity; Humans; Ibogaine; Neurotoxicity Syndromes; Substance-Related Disorders	2016
Ibogaine, an anti-addictive drug: pharmacology and time to go further in development. A narrative review. Human & experimental toxicology, 2008, Volume: 27, Issue:3 Topics: Animals; Chemistry, Pharmaceutical; Humans; Ibogaine; Substance-Related Disorders	2008
[Ibogaine--the substance for treatment of toxicomania. Neurochemical and pharmacological action]. Medicina (Kaunas, Lithuania), 2004, Volume: 40, Issue:3 Topics: Animals; Excitatory Amino Acid Antagonists; Female; Guinea Pigs; Hallucinogens; Humans; Ibogaine; Male; Mice; Rats; Rats, Sprague-Dawley; Substance-Related Disorders; Time Factors	2004
Combating substance abuse with ibogaine: pre- and posttreatment recommendations and an example of successive model fitting analyses. Journal of psychoactive drugs, 2004, Volume: 36, Issue:2 Topics: Adult; Female; Humans; Ibogaine; Linear Models; Male; Models, Theoretical; Substance-Related Disorders	2004
GDNF and addiction. Reviews in the neurosciences, 2005, Volume: 16, Issue:4 Topics: Excitatory Amino Acid Antagonists; Glial Cell Line-Derived Neurotrophic Factor; Glial Cell Line-Derived Neurotrophic Factor Receptors; Humans; Ibogaine; Membrane Microdomains; Signal Transduction; Substance-Related Disorders	2005
100 years of ibogaine: neurochemical and pharmacological actions of a putative anti-addictive drug. Pharmacological reviews, 1995, Volume: 47, Issue:2 Topics: Animals; Calcium; Hallucinogens; Humans; Ibogaine; Neurotoxins; Receptors, GABA; Receptors, Glutamate; Receptors, Opioid; Serotonin; Substance Withdrawal Syndrome; Substance-Related Disorders; Synaptic Transmission	1995
Ibogaine and cocaine abuse: pharmacological interactions at dopamine and serotonin receptors. Brain research bulletin, 1997, Volume: 42, Issue:3 Topics: Animals; Cocaine; Humans; Ibogaine; Receptors, Dopamine; Receptors, Serotonin; Substance-Related Disorders	1997
Assessment of neurotoxicity from potential medications for drug abuse: ibogaine testing and brain imaging. Annals of the New York Academy of Sciences, 1997, May-30, Volume: 820 Topics: Animals; Brain; Hallucinogens; Humans; Ibogaine; Magnetic Resonance Imaging; Radiography; Substance-Related Disorders; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon	1997
Mechanisms of antiaddictive actions of ibogaine. Annals of the New York Academy of Sciences, 1998, May-30, Volume: 844 Topics: Animals; Cocaine; Female; Ibogaine; Morphine; Rats; Rats, Sprague-Dawley; Self Administration; Substance-Related Disorders; Tobacco Use Disorder	1998
Medication development of ibogaine as a pharmacotherapy for drug dependence. Annals of the New York Academy of Sciences, 1998, May-30, Volume: 844 Topics: Animals; Behavior, Animal; Humans; Ibogaine; Substance-Related Disorders; Technology, Pharmaceutical	1998
Iboga interactions with psychomotor stimulants: panacea in the paradox? Toxicon : official journal of the International Society on Toxinology, 2001, Volume: 39, Issue:1 Topics: Animals; Central Nervous System Stimulants; Dopamine; Humans; Ibogaine; Substance-Related Disorders	2001
Characterization of multiple sites of action of ibogaine. The Alkaloids. Chemistry and biology, 2001, Volume: 56 Topics: Alcohol Drinking; Animals; Binding Sites; Dopamine; Humans; Ibogaine; Receptors, N-Methyl-D-Aspartate; Substance-Related Disorders	2001
Changes in gene expression and signal transduction following ibogaine treatment. The Alkaloids. Chemistry and biology, 2001, Volume: 56 Topics: Animals; Calcium; Cocaine; Gene Expression Regulation; Humans; Ibogaine; Nucleus Accumbens; Oligonucleotide Array Sequence Analysis; Protein Kinase C; Signal Transduction; Substance-Related Disorders	2001
Modulation of the effects of rewarding drugs by ibogaine. The Alkaloids. Chemistry and biology, 2001, Volume: 56 Topics: Animals; Drug Synergism; Humans; Ibogaine; Learning; Morphine; Reward; Substance Withdrawal Syndrome; Substance-Related Disorders	2001
Ibogaine as a glutamate antagonist: relevance to its putative antiaddictive properties. The Alkaloids. Chemistry and biology, 2001, Volume: 56 Topics: Animals; Excitatory Amino Acid Antagonists; Humans; Ibogaine; Receptors, N-Methyl-D-Aspartate; Substance-Related Disorders	2001
Ibogaine signals addiction genes and methamphetamine alteration of long-term potentiation. Annals of the New York Academy of Sciences, 2002, Volume: 965 Topics: Gene Expression Regulation; Hallucinogens; Humans; Ibogaine; Long-Term Potentiation; Methamphetamine; Substance-Related Disorders; Tabernaemontana	2002

Trials

2 trial(s) available for ibogaine and Chemical Dependence

Article	Year
Observations on treatment with ibogaine. The American journal on addictions, 1998,Winter, Volume: 7, Issue:1 Topics: Hallucinogens; Humans; Ibogaine; Substance-Related Disorders	1998
Ibogaine: complex pharmacokinetics, concerns for safety, and preliminary efficacy measures. Annals of the New York Academy of Sciences, 2000, Volume: 914 Topics: Adult; Cocaine; Depression; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Humans; Ibogaine; Male; Narcotics; Substance-Related Disorders; Surveys and Questionnaires; Time Factors	2000

Other Studies

42 other study(ies) available for ibogaine and Chemical Dependence

Article	Year
Underground ibogaine use for the treatment of substance use disorders: A qualitative analysis of subjective experiences. Drug and alcohol review, 2023, Volume: 42, Issue:2 Topics: Alkaloids; Humans; Ibogaine; Substance-Related Disorders; Tabernaemontana	2023
A non-hallucinogenic psychedelic analogue with therapeutic potential. Nature, 2021, Volume: 589, Issue:7842 Topics: Alcoholism; Animals; Antidepressive Agents; Arrhythmias, Cardiac; Behavior, Addictive; Chemistry Techniques, Synthetic; Depression; Disease Models, Animal; Drug Design; Female; Hallucinogens; Heroin Dependence; Ibogaine; Male; Mice; Mice, Inbred C57BL; Neuronal Plasticity; Patient Safety; Receptor, Serotonin, 5-HT2A; Serotonin 5-HT2 Receptor Agonists; Substance-Related Disorders; Swimming; Tabernaemontana	2021
Treating drug dependence with the aid of ibogaine: a retrospective study. Journal of psychopharmacology (Oxford, England), 2014, Volume: 28, Issue:11 Topics: Adult; Brazil; Combined Modality Therapy; Female; Hallucinogens; Humans; Ibogaine; Male; Psychotherapy; Recurrence; Retrospective Studies; Substance-Related Disorders; Treatment Outcome; Young Adult	2014
Pharmacotherapy: Quest for the quitting pill. Nature, 2015, Jun-25, Volume: 522, Issue:7557 Topics: Animals; Behavior, Addictive; Buprenorphine; Buprenorphine, Naloxone Drug Combination; Clinical Trials as Topic; Cocaine-Related Disorders; Counseling; Dopamine; Drug Discovery; Drug Industry; Humans; Ibogaine; Lobeline; Molecular Targeted Therapy; Naloxone; Naltrexone; Oligopeptides; Opioid-Related Disorders; Pleasure; Rats; Receptors, Nicotinic; Reward; Substance-Related Disorders; Tobacco Use Disorder; Vaccines; Vesicular Monoamine Transport Proteins	2015
Noribogaine is a G-protein biased κ-opioid receptor agonist. Neuropharmacology, 2015, Volume: 99 Topics: Analgesics, Opioid; Animals; Arrestins; beta-Arrestins; CHO Cells; Computer Simulation; Cricetulus; Drug Evaluation, Preclinical; Dynorphins; GTP-Binding Proteins; Humans; Ibogaine; Mesencephalon; Mice; Models, Molecular; Morphinans; Rats; Receptors, Opioid, kappa; Receptors, Opioid, mu; Signal Transduction; Substance-Related Disorders	2015
Anti-addiction Drug Ibogaine Prolongs the Action Potential in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Cardiovascular toxicology, 2017, Volume: 17, Issue:2 Topics: Action Potentials; Arrhythmias, Cardiac; Cell Differentiation; Cells, Cultured; Dose-Response Relationship, Drug; Heart Rate; Humans; Ibogaine; Induced Pluripotent Stem Cells; Myocytes, Cardiac; Neurotransmitter Agents; Patch-Clamp Techniques; Risk Assessment; Substance-Related Disorders; Time Factors	2017
Get Clean or Die Trying. Scientific American, 2016, Oct-18, Volume: 315, Issue:5 Topics: Acetylcholine; Arrhythmias, Cardiac; Brain; Dopamine; Excitatory Amino Acid Antagonists; Female; Hallucinogens; Heart Arrest; Heroin Dependence; Humans; Ibogaine; Male; Serotonin; Substance-Related Disorders	2016
Long-QT syndrome induced by the antiaddiction drug ibogaine. The New England journal of medicine, 2009, Jan-15, Volume: 360, Issue:3 Topics: Adult; Female; Hallucinogens; Humans; Ibogaine; Long QT Syndrome; Substance-Related Disorders	2009
Ibogaine--be informed before you promote or prescribe. Journal of primary health care, 2011, Mar-01, Volume: 3, Issue:1 Topics: Humans; Ibogaine; New Zealand; Physician-Patient Relations; Practice Patterns, Physicians'; Primary Health Care; Substance-Related Disorders	2011
The need for ibogaine in drug and alcohol addiction treatment. The Journal of legal medicine, 2011, Volume: 32, Issue:1 Topics: Alcoholism; Animals; Clinical Trials as Topic; Cost Control; Cross-Sectional Studies; Drug Approval; Drug Costs; Excitatory Amino Acid Antagonists; Health Services Needs and Demand; Humans; Ibogaine; Illicit Drugs; Psychotropic Drugs; Substance-Related Disorders; United States; United States Food and Drug Administration	2011
Fatalities temporally associated with the ingestion of ibogaine. Journal of forensic sciences, 2012, Volume: 57, Issue:2 Topics: Adult; Brain Neoplasms; Cardiovascular Diseases; Female; Forensic Toxicology; Hallucinogens; Humans; Ibogaine; Liver Diseases; Male; Middle Aged; Obesity; Peptic Ulcer; Risk Factors; Seizures; Substance Withdrawal Syndrome; Substance-Related Disorders; Young Adult	2012
Serotonergic hallucinogens and emerging targets for addiction pharmacotherapies. The Psychiatric clinics of North America, 2012, Volume: 35, Issue:2 Topics: Adult; Animals; Behavior, Addictive; Clinical Trials as Topic; Cognition; Dopamine; Dopamine Agonists; Glutamates; Hallucinogens; Humans; Ibogaine; Lysergic Acid; Neuronal Plasticity; Nucleus Accumbens; Phytotherapy; Prefrontal Cortex; Psilocybin; Religion; Reward; Serotonin 5-HT2 Receptor Agonists; Substance Withdrawal Syndrome; Substance-Related Disorders	2012
Metabolic plasticity and the energy economizing effect of ibogaine, the principal alkaloid of Tabernanthe iboga. Journal of ethnopharmacology, 2012, Aug-30, Volume: 143, Issue:1 Topics: Adenosine Triphosphate; Biphenyl Compounds; Carbon Dioxide; Dose-Response Relationship, Drug; Energy Metabolism; Ibogaine; Medicine, African Traditional; Oxidative Stress; Phytotherapy; Picrates; Plant Bark; Plant Extracts; Plant Roots; Substance-Related Disorders; Tabernaemontana; Yeasts	2012
Life-threatening complications of ibogaine: three case reports. The Netherlands journal of medicine, 2012, Volume: 70, Issue:9 Topics: Adult; Female; Humans; Ibogaine; Male; Middle Aged; Substance-Related Disorders; Tachycardia; Tachycardia, Ventricular; Torsades de Pointes	2012
Addiction treatment strives for legitimacy. JAMA, 2002, Dec-25, Volume: 288, Issue:24 Topics: Animals; Central Nervous System Agents; Clinical Trials as Topic; Drug Evaluation, Preclinical; Humans; Ibogaine; Legislation, Drug; Substance-Related Disorders	2002
Synthesis and biological evaluation of 18-methoxycoronaridine congeners. Potential antiaddiction agents. Journal of medicinal chemistry, 2003, Jun-19, Volume: 46, Issue:13 Topics: Animals; Cell Line; Humans; Ibogaine; Morphine Dependence; Patch-Clamp Techniques; Rats; Receptors, Nicotinic; Receptors, Opioid; Self Administration; Stereoisomerism; Structure-Activity Relationship; Substance-Related Disorders	2003
Addiction research. Ibogaine therapy: a 'vast, uncontrolled experiment'. Science (New York, N.Y.), 2005, Apr-15, Volume: 308, Issue:5720 Topics: Animals; Brain; Clinical Trials as Topic; Dopamine; Glial Cell Line-Derived Neurotrophic Factor; Glutamic Acid; Hallucinations; Hallucinogens; Humans; Ibogaine; Nerve Growth Factors; Receptors, Nicotinic; Receptors, Opioid; Selective Serotonin Reuptake Inhibitors; Serotonin; Substance-Related Disorders	2005
Fatalities after taking ibogaine in addiction treatment could be related to sudden cardiac death caused by autonomic dysfunction. Medical hypotheses, 2006, Volume: 67, Issue:4 Topics: Autonomic Nervous System; Death, Sudden, Cardiac; Humans; Ibogaine; Models, Neurological; Substance-Related Disorders	2006
Ibogaine may help drug addicts live the 'never again'. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2006, Volume: 96, Issue:7 Topics: Clinical Trials as Topic; Excitatory Amino Acid Antagonists; Humans; Ibogaine; South Africa; Substance Withdrawal Syndrome; Substance-Related Disorders	2006
The ibogaine medical subculture. Journal of ethnopharmacology, 2008, Jan-04, Volume: 115, Issue:1 Topics: Data Collection; Hallucinogens; Humans; Ibogaine; Internet; Medicine, African Traditional; Opioid-Related Disorders; Substance Withdrawal Syndrome; Substance-Related Disorders	2008
NMDA antagonist properties of the putative antiaddictive drug, ibogaine. The Journal of pharmacology and experimental therapeutics, 1995, Volume: 275, Issue:2 Topics: Animals; Cerebellum; Dizocilpine Maleate; Electric Conductivity; Excitatory Amino Acid Antagonists; Hippocampus; Ibogaine; Male; Mice; Naloxone; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome; Substance-Related Disorders	1995
Receptor binding profile suggests multiple mechanisms of action are responsible for ibogaine's putative anti-addictive activity. Psychopharmacology, 1995, Volume: 118, Issue:4 Topics: Animals; Binding Sites; Carrier Proteins; Cattle; Evaluation Studies as Topic; Ibogaine; Kinetics; Radioligand Assay; Rats; Receptors, Drug; Receptors, Muscarinic; Receptors, Opioid, kappa; Substance-Related Disorders	1995
Effects of iboga alkaloids on morphine and cocaine self-administration in rats: relationship to tremorigenic effects and to effects on dopamine release in nucleus accumbens and striatum. Brain research, 1994, Sep-19, Volume: 657, Issue:1-2 Topics: Alkaloids; Animals; Cocaine; Corpus Striatum; Dopamine; Female; Harmaline; Ibogaine; Microdialysis; Morphine Dependence; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Self Administration; Substance-Related Disorders; Tremor	1994
Ibogaine reduces preference for cocaine consumption in C57BL/6By mice. Pharmacology, biochemistry, and behavior, 1994, Volume: 47, Issue:1 Topics: Animals; Brain; Cocaine; Drinking; Ibogaine; Male; Mice; Mice, Inbred C57BL; Motor Activity; Stereotyped Behavior; Substance-Related Disorders	1994
Inhibitory effects of ibogaine on cocaine self-administration in rats. European journal of pharmacology, 1993, Sep-14, Volume: 241, Issue:2-3 Topics: Analysis of Variance; Animals; Brain; Cocaine; Disease Models, Animal; Drug Administration Schedule; Ibogaine; Male; Motor Activity; Rats; Rats, Wistar; Self Administration; Substance-Related Disorders	1993
Ibogaine-like effects of noribogaine in rats. Brain research, 1996, Mar-25, Volume: 713, Issue:1-2 Topics: Animals; Female; Ibogaine; Locomotion; Medicine, African Traditional; Morphine; Rats; Rats, Sprague-Dawley; Self Administration; Substance-Related Disorders; Time Factors	1996
Facilitation of memory retrieval by the "anti-addictive" alkaloid, ibogaine. Life sciences, 1996, Volume: 59, Issue:24 Topics: Animals; Ibogaine; Male; Memory; Nootropic Agents; Rats; Rats, Wistar; Substance-Related Disorders	1996
The effects of noribogaine and harmaline in rats trained with ibogaine as a discriminative stimulus. Life sciences, 1997, Volume: 60, Issue:9 Topics: Animals; Discrimination Learning; Hallucinogens; Harmaline; Humans; Ibogaine; Male; Rats; Rats, Inbred F344; Substance-Related Disorders; Time Factors	1997
Evidence for roles of kappa-opioid and NMDA receptors in the mechanism of action of ibogaine. Brain research, 1997, Feb-28, Volume: 749, Issue:2 Topics: Animals; Corpus Striatum; Dopamine; Female; Ibogaine; Morphine; Motor Activity; N-Methylaspartate; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, kappa; Self Administration; Substance-Related Disorders	1997
Ibogaine effects on sweet preference and amphetamine induced locomotion: implications for drug addiction. Behavioural brain research, 1997, Volume: 89, Issue:1-2 Topics: Amphetamine; Animals; Central Nervous System Stimulants; Cues; Dopamine; Dopamine Antagonists; Drug Interactions; Food Preferences; Ibogaine; Male; Motor Activity; Psychotropic Drugs; Rats; Reward; Substance-Related Disorders; Synaptic Transmission; Taste	1997
Fight to develop drug addiction therapy. Nature medicine, 1998, Volume: 4, Issue:4 Topics: Clinical Trials as Topic; Humans; Ibogaine; National Institutes of Health (U.S.); Substance-Related Disorders; United States; United States Food and Drug Administration	1998
The Neurochemistry of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetamines. Proceedings of a meeting. Hamilton, Bermuda, July 16-18, 1997. Annals of the New York Academy of Sciences, 1998, May-30, Volume: 844 Topics: Amphetamines; Animals; Brain; Cocaine; Humans; Ibogaine; Neurochemistry; Substance-Related Disorders	1998
Cellular and Molecular Mechanisms of Drugs of Abuse: Cocaine, Ibogaine, and Substituted Amphetamines. Proceedings of a conference. Niigata City, Japan, June 29-30, 1995. Annals of the New York Academy of Sciences, 1996, Oct-31, Volume: 801 Topics: Amphetamines; Animals; Central Nervous System; Cocaine; Humans; Ibogaine; Substance-Related Disorders	1996
Data accrue on "visionary" agent to interrupt addiction. Lancet (London, England), 1999, Nov-27, Volume: 354, Issue:9193 Topics: Hallucinogens; Humans; Ibogaine; Substance-Related Disorders	1999
For heroin addicts, a bizarre remedy. Lack of cure spurs interest in an exotic shrub. U.S. news & world report, 1999, Dec-06, Volume: 127, Issue:22 Topics: Africa, Western; Heroin; Humans; Ibogaine; Receptors, Glutamate; Substance-Related Disorders; United States	1999
Pharmacokinetic characterization of the indole alkaloid ibogaine in rats. Methods and findings in experimental and clinical pharmacology, 2000, Volume: 22, Issue:2 Topics: Animals; Female; Half-Life; Ibogaine; Models, Biological; Psychotropic Drugs; Rats; Rats, Sprague-Dawley; Substance-Related Disorders; Tissue Distribution	2000
Development of novel medications for drug addiction. The legacy of an African shrub. Annals of the New York Academy of Sciences, 2000, Volume: 909 Topics: Animals; Cocaine; Dose-Response Relationship, Drug; Female; Ibogaine; Morphine; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Self Administration; Substance-Related Disorders	2000
The development and expression of locomotor sensitization to nicotine in the presence of ibogaine. Behavioural pharmacology, 2000, Volume: 11, Issue:5 Topics: Animals; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Ganglionic Stimulants; Ibogaine; Locomotion; Male; Nicotine; Rats; Substance-Related Disorders	2000
A contemporary history of ibogaine in the United States and Europe. The Alkaloids. Chemistry and biology, 2001, Volume: 56 Topics: Europe; Excitatory Amino Acid Antagonists; Hallucinogens; History, 20th Century; Humans; Ibogaine; Patient Advocacy; Substance-Related Disorders; United States	2001
From the roots up: ibogaine and addict self-help. The Alkaloids. Chemistry and biology, 2001, Volume: 56 Topics: Humans; Ibogaine; Self-Help Groups; Substance-Related Disorders	2001
Case studies of ibogaine treatment: implications for patient management strategies. The Alkaloids. Chemistry and biology, 2001, Volume: 56 Topics: Humans; Ibogaine; Self-Help Groups; Substance-Related Disorders	2001
Extraction studies of Tabernanthe iboga and Voacanga africana. Natural product letters, 2002, Volume: 16, Issue:1 Topics: Alkaloids; Bridged-Ring Compounds; Chromatography, Thin Layer; Ibogaine; Indole Alkaloids; Molecular Structure; Plant Bark; Plant Roots; Plants, Medicinal; Substance-Related Disorders; Tabernaemontana	2002