i(3)so3-galactosylceramide and Myocardial-Infarction

i(3)so3-galactosylceramide has been researched along with Myocardial-Infarction* in 1 studies

Other Studies

1 other study(ies) available for i(3)so3-galactosylceramide and Myocardial-Infarction

Article	Year
Antibodies to sulfatide in cerebrospinal fluid of patients with multiple sclerosis. Journal of neuroimmunology, 2003, Volume: 139, Issue:1-2 The identity of target antigen(s) in multiple sclerosis (MS) remains elusive despite much effort to identify it. We analyzed cerebrospinal fluid (CSF) from patients with MS, other neurological diseases (OND), other diseases (OD) and healthy controls for antibodies against purified sulfatide, a major glycosphingolipid of human myelin, by an enzyme-linked immunosorbent assay (ELISA) and a thin-layer chromatogram (TLC)-immunostaining technique. Elevated anti-sulfatide antibodies were significantly higher in MS patients as compared with the OND group (p<0.05) and all controls combined (P<0.025). Binding of high titer antibodies to sulfatide was confirmed with TLC-immunostaining. Anti-sulfatide antibodies were detected in all subtypes of MS although the frequency was higher in patients with secondary progressive MS (SPMS) than in patients with primary progressive (PPMS) and relapsing-remitting MS (RRMS). The data demonstrate a humoral response to sulfatide in the CSF of patients with MS. Topics: Adult; Aged; Aged, 80 and over; Autoantibodies; Central Nervous System Diseases; Chromatography, Thin Layer; Diabetes Mellitus; Enzyme-Linked Immunosorbent Assay; Female; Humans; Lupus Vulgaris; Male; Middle Aged; Multiple Sclerosis; Myelin Sheath; Myocardial Infarction; Neoplasms; Protein Binding; Recurrence; Sulfoglycosphingolipids	2003

Article

Year

Antibodies to sulfatide in cerebrospinal fluid of patients with multiple sclerosis.

Journal of neuroimmunology, 2003, Volume: 139, Issue:1-2

The identity of target antigen(s) in multiple sclerosis (MS) remains elusive despite much effort to identify it. We analyzed cerebrospinal fluid (CSF) from patients with MS, other neurological diseases (OND), other diseases (OD) and healthy controls for antibodies against purified sulfatide, a major glycosphingolipid of human myelin, by an enzyme-linked immunosorbent assay (ELISA) and a thin-layer chromatogram (TLC)-immunostaining technique. Elevated anti-sulfatide antibodies were significantly higher in MS patients as compared with the OND group (p<0.05) and all controls combined (P<0.025). Binding of high titer antibodies to sulfatide was confirmed with TLC-immunostaining. Anti-sulfatide antibodies were detected in all subtypes of MS although the frequency was higher in patients with secondary progressive MS (SPMS) than in patients with primary progressive (PPMS) and relapsing-remitting MS (RRMS). The data demonstrate a humoral response to sulfatide in the CSF of patients with MS.

Topics: Adult; Aged; Aged, 80 and over; Autoantibodies; Central Nervous System Diseases; Chromatography, Thin Layer; Diabetes Mellitus; Enzyme-Linked Immunosorbent Assay; Female; Humans; Lupus Vulgaris; Male; Middle Aged; Multiple Sclerosis; Myelin Sheath; Myocardial Infarction; Neoplasms; Protein Binding; Recurrence; Sulfoglycosphingolipids

2003