i(3)so3-galactosylceramide and Brain-Damage--Chronic

i(3)so3-galactosylceramide has been researched along with Brain-Damage--Chronic* in 2 studies

Other Studies

2 other study(ies) available for i(3)so3-galactosylceramide and Brain-Damage--Chronic

Article	Year
Chronic brain damage in HIV-infected individuals under antiretroviral therapy is associated with viral reservoirs, sulfatide release, and compromised cell-to-cell communication. Cellular and molecular life sciences : CMLS, 2023, Apr-04, Volume: 80, Issue:4 HIV infection has become a chronic and manageable disease due to the effective use of antiretroviral therapies (ART); however, several chronic aging-related comorbidities, including cognitive impairment, remain a major public health issue. However, these mechanisms are unknown. Here, we identified that glial and myeloid viral reservoirs are associated with local myelin damage and the release of several myelin components, including the lipid sulfatide. Soluble sulfatide compromised gap junctional communication and calcium wave coordination, essential for proper cognition. We propose that soluble sulfatide could be a potential biomarker and contributor to white matter compromise observed in HIV-infected individuals even in the current ART era. Topics: Brain Damage, Chronic; Cell Communication; HIV Infections; Humans; Sulfoglycosphingolipids; White Matter	2023
Hypoglycemia and brain development. Pediatrics, 1973, Volume: 52, Issue:4 Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Brain; Brain Damage, Chronic; Cerebrosides; Cholesterol; DNA; Gangliosides; Glucose; Glycogen; Humans; Hypoglycemia; Infant, Newborn; Infant, Newborn, Diseases; Lipid Metabolism; Nerve Tissue Proteins; Organ Size; Phosphocreatine; Phospholipids; Rats; Sulfoglycosphingolipids	1973

Article

Year

Chronic brain damage in HIV-infected individuals under antiretroviral therapy is associated with viral reservoirs, sulfatide release, and compromised cell-to-cell communication.

Cellular and molecular life sciences : CMLS, 2023, Apr-04, Volume: 80, Issue:4

HIV infection has become a chronic and manageable disease due to the effective use of antiretroviral therapies (ART); however, several chronic aging-related comorbidities, including cognitive impairment, remain a major public health issue. However, these mechanisms are unknown. Here, we identified that glial and myeloid viral reservoirs are associated with local myelin damage and the release of several myelin components, including the lipid sulfatide. Soluble sulfatide compromised gap junctional communication and calcium wave coordination, essential for proper cognition. We propose that soluble sulfatide could be a potential biomarker and contributor to white matter compromise observed in HIV-infected individuals even in the current ART era.

Topics: Brain Damage, Chronic; Cell Communication; HIV Infections; Humans; Sulfoglycosphingolipids; White Matter

2023

Hypoglycemia and brain development.

Pediatrics, 1973, Volume: 52, Issue:4

Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Brain; Brain Damage, Chronic; Cerebrosides; Cholesterol; DNA; Gangliosides; Glucose; Glycogen; Humans; Hypoglycemia; Infant, Newborn; Infant, Newborn, Diseases; Lipid Metabolism; Nerve Tissue Proteins; Organ Size; Phosphocreatine; Phospholipids; Rats; Sulfoglycosphingolipids

1973