hypoxanthine and Myocardial Ischemia

hypoxanthine has been researched along with Myocardial Ischemia in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's19 (57.58)18.2507
2000's12 (36.36)29.6817
2010's2 (6.06)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Farthing, CA; Farthing, DE; Xi, L1
Dai, W; Liang, X; Liu, X; Lv, Y; Yan, S; Yang, Y; Zhang, W1
Barát, E; Horkay, F; Huszár, E; Juhász-Nagy, A; Kékesi, V; Losonczi, L; Merkely, B; Nagy, A; Zima, E1
Bäckström, T; Franco-Cereceda, A; Goiny, M; Liska, J; Lockowandt, U1
Gonçalves, L; Monteiro, P; Moreno, AJ; Oliveira, PJ; Palmeira, CM; Rolo, AP1
Kavianipour, M; Ronquist, G; Waldenström, A; Wikström, G1
Garnham, B; Headrick, JP; Willems, L1
Goiny, M; Owall, A; Takeshima, S; Ungerstedt, U; Vaage, J; Valen, G1
Athias, P; Bès, S; Rochette, L; Tatou, E; Tissier, C; Vandroux, D1
Barát, E; Huszár, E; Juhász-Nagy, A; Kékesi, V; Merkely, B; Nagy, A; Toma, I; Zima, E1
Baldus, S; Chumley, P; Freeman, BA; Heitzer, T; Kähler, J; Köster, R; Lund, GK; Meinertz, T; Müllerleile, K; Münzel, T; Rudolph, V; Staude, HJ; Steven, D; Stork, A; Weiss, C1
Fakhry, I; Farthing, C; Farthing, D; Gehr, T; Karnes, HT; Larus, T; Sica, D; Wilson, B1
Bradamante, S; Bünger, R; Cargnoni, A; Ceconi, C; Curello, S; de Jong, JW; Ferrari, R; Janssen, M; Pasini, E1
Maripu, E; Nilsson, S; Ronquist, G; Waldenström, A; Wikström, G1
Delvoux, B; Greiling, H; Kock, R; Sigmund, M1
Bartels, GL; Kruijssen, DA; Pillay, M; Remme, WJ; Schönfeld, DH1
Van Wylen, DG1
Coetzee, IH; Lochner, A1
Caldarera, CM; Finelli, C; Guarnieri, C; Muscari, C; Ventura, C1
Barclay, KD; Buckley, SJ; Feng, JD; Hung, OR; Klassen, GA; Pollak, PT; Yeung, PK1
Manthei, SA; Reiling, CM; Van Wylen, DG1
Jayakumar, J; Seymour, AM; Smolenski, RT; Yacoub, MH1
Biagioli, B; Carlucci, F; Maccherini, M; Marinello, E; Perrett, D; Sani, G; Simeone, F; Tabucchi, A1
Makarewicz, W; Smolenski, RT; Yacoub, MH; Zych, M1
Gross, GJ; Lasley, RD; Mei, DA; Nithipatikom, K1
Richardt, G; Schreieck, J1
Bayindir, O; Boydak, B; Gülter, C; Habif, S; Mutaf, I; Ozmen, D; Senol, B; Turgan, N1
Headrick, JP; Peart, J1
Henze, A; Ronquist, G; Thelin, S; Waldenström, A; Wikström, G; Zemgulis, V1
Blakeman, B; Dries, DJ; Kleinman, B; Kumar, P; Mathru, M; Sullivan, H1
Brunvand, H; Grong, K; Lekven, J; Westby, J1
Wysocki, H1
Coumans, WA; de Groot, MJ; van der Vusse, GJ1

Reviews

2 review(s) available for hypoxanthine and Myocardial Ischemia

ArticleYear
Inosine and hypoxanthine as novel biomarkers for cardiac ischemia: from bench to point-of-care.
    Experimental biology and medicine (Maywood, N.J.), 2015, Volume: 240, Issue:6

    Topics: Adenosine Triphosphate; Animals; Biomarkers; Humans; Hypoxanthine; Inosine; Myocardial Ischemia; Point-of-Care Systems

2015
The role of polymorphonuclear neutrophils in myocardial damage during ischemia and reperfusion.
    Archivum immunologiae et therapiae experimentalis, 1992, Volume: 40, Issue:1

    Topics: Animals; Antioxidants; Capillary Resistance; Cell Adhesion; Endopeptidases; Endothelium, Vascular; Free Radicals; Humans; Hypoxanthine; Hypoxanthines; Leukotrienes; Myocardial Ischemia; Myocardial Reperfusion Injury; Neutrophils; Oxygen; Platelet Activating Factor; Platelet Aggregation; Respiratory Burst

1992

Trials

1 trial(s) available for hypoxanthine and Myocardial Ischemia

ArticleYear
Effects of L-propionylcarnitine on ischemia-induced myocardial dysfunction in men with angina pectoris.
    The American journal of cardiology, 1994, Jul-15, Volume: 74, Issue:2

    Topics: Aged; Angina Pectoris; Cardiac Output; Cardiotonic Agents; Carnitine; Coronary Disease; Electrocardiography; Exercise Test; Heart; Heart Rate; Humans; Hypoxanthine; Hypoxanthines; Lactates; Male; Middle Aged; Myocardial Contraction; Myocardial Ischemia; Placebos; Stroke Volume; Ventricular Function, Left; Ventricular Pressure

1994

Other Studies

30 other study(ies) available for hypoxanthine and Myocardial Ischemia

ArticleYear
Metabolomic study of myocardial ischemia and intervention effects of Compound Danshen Tablets in rats using ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry.
    Journal of pharmaceutical and biomedical analysis, 2010, May-01, Volume: 52, Issue:1

    Topics: Allantoin; Animals; Biomarkers; Cardiovascular Agents; Chromatography, Liquid; Disease Models, Animal; Drugs, Chinese Herbal; Hypoxanthine; Inosine; Least-Squares Analysis; Male; Metabolomics; Myocardial Ischemia; Principal Component Analysis; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Salvia miltiorrhiza; Spectrometry, Mass, Electrospray Ionization; Tablets; Xanthine

2010
Pericardial concentrations of adenosine, inosine and hypoxanthine in an experimental canine model of spastic ischaemia.
    Clinical science (London, England : 1979), 2002, Volume: 103 Suppl 48

    Topics: Adenosine; Animals; Coronary Vasospasm; Dogs; Endothelin-1; Hypoxanthine; Inosine; Models, Animal; Myocardial Ischemia; Pericardium; Vasoconstrictor Agents

2002
Cardiac outflow of amino acids and purines during myocardial ischemia and reperfusion.
    Journal of applied physiology (Bethesda, Md. : 1985), 2003, Volume: 94, Issue:3

    Topics: Amino Acids; Animals; Aspartic Acid; Female; Guanosine; Hemodynamics; Hypoxanthine; Inosine; Male; Microdialysis; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Purines; Swine; Taurine

2003
Impact of carvedilol on the mitochondrial damage induced by hypoxanthine and xantine oxidase--what role in myocardial ischemia and reperfusion?
    Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology, 2002, Volume: 21, Issue:12

    Topics: Animals; Antioxidants; Carbazoles; Carvedilol; Hypoxanthine; Male; Mitochondria, Heart; Myocardial Ischemia; Myocardial Reperfusion; Propanolamines; Rats; Rats, Wistar; Xanthine Oxidase

2002
Validity of the microdialysis technique for experimental in vivo studies of myocardial energy metabolism.
    Acta physiologica Scandinavica, 2003, Volume: 179, Issue:1

    Topics: Adenosine; Animals; Biopsy; Energy Metabolism; Hypoxanthine; Inosine; Lactic Acid; Microdialysis; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Reproducibility of Results; Swine

2003
Aging-related changes in myocardial purine metabolism and ischemic tolerance.
    Experimental gerontology, 2003, Volume: 38, Issue:10

    Topics: Adenosine; Aging; Animals; Female; Hypoxanthine; Inosine; Male; Mice; Mice, Inbred C57BL; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Organ Culture Techniques; Purines

2003
Metabolic changes induced by ischemia and cardioplegia: a study employing cardiac microdialysis in pigs.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2004, Volume: 25, Issue:1

    Topics: Analysis of Variance; Animals; Arteries; Citrulline; Extracorporeal Circulation; Female; Guanosine; Heart Arrest, Induced; Heart Ventricles; Hypoxanthine; Inosine; Lactates; Male; Microdialysis; Myocardial Ischemia; Swine

2004
Physiological and metabolic actions of mycophenolate mofetil on cultured newborn rat cardiomyocytes in normoxia and in simulated ischemia.
    Fundamental & clinical pharmacology, 2004, Volume: 18, Issue:3

    Topics: Adenosine; Animals; Animals, Newborn; Cell Hypoxia; Cells, Cultured; Hypoxanthine; Immunosuppressive Agents; Membrane Potentials; Mycophenolic Acid; Myocardial Ischemia; Myocardial Reperfusion; Myocytes, Cardiac; Rats; Rats, Wistar; Xanthine

2004
Nitrogen oxide blockade does not aggravate the endothelin-1-induced myocardial ischemia and release of purine metabolites from the dog heart.
    Journal of cardiovascular pharmacology, 2004, Volume: 44 Suppl 1

    Topics: Adaptation, Physiological; Adenosine; Animals; Disease Models, Animal; Dogs; Endothelin-1; Enzyme Inhibitors; Hemodynamics; Hypoxanthine; Inosine; Myocardial Ischemia; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pericardium; Purines

2004
Inhibition of xanthine oxidase improves myocardial contractility in patients with ischemic cardiomyopathy.
    Free radical biology & medicine, 2006, Oct-15, Volume: 41, Issue:8

    Topics: Aged; Cardiomyopathies; Cardiotonic Agents; Enzyme Inhibitors; Female; Humans; Hypoxanthine; Magnetic Resonance Imaging, Cine; Male; Middle Aged; Myocardial Contraction; Myocardial Ischemia; Oxypurinol; Reactive Oxygen Species; Uric Acid; Xanthine; Xanthine Oxidase

2006
An HPLC method for determination of inosine and hypoxanthine in human plasma from healthy volunteers and patients presenting with potential acute cardiac ischemia.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2007, Jul-01, Volume: 854, Issue:1-2

    Topics: Case-Control Studies; Chromatography, High Pressure Liquid; Female; Humans; Hypoxanthine; Inosine; Myocardial Ischemia; Purine-Nucleoside Phosphorylase; Reference Standards; Reproducibility of Results; Sensitivity and Specificity

2007
Intermittent v continuous ischemia decelerates adenylate breakdown and prevents norepinephrine release in reperfused rabbit heart.
    Journal of molecular and cellular cardiology, 1995, Volume: 27, Issue:1

    Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Analysis of Variance; Animals; Heart; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Kinetics; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Norepinephrine; Purines; Rabbits; Time Factors; Ventricular Function, Left

1995
Continuous monitoring of energy metabolites using microdialysis during myocardial ischaemia in the pig.
    European heart journal, 1995, Volume: 16, Issue:3

    Topics: Adenosine; Animals; Energy Metabolism; Female; Guanosine; Hemodynamics; Hypoxanthine; Hypoxanthines; Inosine; Lactates; Lactic Acid; Male; Microdialysis; Monitoring, Physiologic; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Pyruvates; Pyruvic Acid; Swine

1995
A comparative study of the concentrations of hypoxanthine, xanthine, uric acid and allantoin in the peripheral blood of normals and patients with acute myocardial infarction and other ischaemic diseases.
    European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies, 1994, Volume: 32, Issue:11

    Topics: Adult; Allantoin; Creatine Kinase; Female; Humans; Hypoxanthine; Hypoxanthines; Isoenzymes; Male; Myocardial Infarction; Myocardial Ischemia; Reference Values; Uric Acid; Xanthine; Xanthines

1994
Effect of ischemic preconditioning on interstitial purine metabolite and lactate accumulation during myocardial ischemia.
    Circulation, 1994, Volume: 89, Issue:5

    Topics: Adenosine; Animals; Dogs; Extracellular Space; Female; Hypoxanthine; Hypoxanthines; Inosine; Lactates; Lactic Acid; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Purines; Time Factors

1994
Free radical effects on myocardial membrane microviscosity.
    Cardioscience, 1993, Volume: 4, Issue:4

    Topics: Animals; Free Radicals; Hypoxanthine; Hypoxanthines; Intracellular Membranes; Lipid Peroxidation; Male; Malondialdehyde; Membrane Fluidity; Mitochondria, Heart; Myocardial Ischemia; Myocardium; Phosphatidylcholines; Phosphatidylethanolamines; Rats; Rats, Wistar; Reactive Oxygen Species; Viscosity; Xanthine Oxidase

1993
Incorporation of [14C]hypoxanthine into cardiac adenine nucleotides: effect of aging and post-ischemic reperfusion.
    Biochimica et biophysica acta, 1993, Jan-22, Volume: 1180, Issue:3

    Topics: Adenine Nucleotides; Aging; Animals; Hypoxanthine; Hypoxanthines; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Rats; Rats, Wistar; Uric Acid

1993
Effect of diltiazem on plasma concentrations of oxypurines and uric acid.
    Therapeutic drug monitoring, 1997, Volume: 19, Issue:3

    Topics: Adenosine; Adult; Cardiovascular Agents; Diltiazem; Female; Guanosine; Humans; Hypoxanthine; Inosine; Male; Myocardial Ischemia; Purines; Uric Acid; Xanthine; Xanthines

1997
Dual cardiac microdialysis to assess drug-induced changes in interstitial purine metabolites: adenosine deaminase inhibition versus adenosine kinase inhibition.
    Cardiovascular research, 1998, Volume: 37, Issue:1

    Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Chromatography, High Pressure Liquid; Extracellular Space; Hypoxanthine; Inosine; Male; Microdialysis; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Rabbits; Tubercidin

1998
The effects of nucleotide pool on purine production in the postischemic heart.
    Advances in experimental medicine and biology, 1998, Volume: 431

    Topics: Adenosine; Adenosine Triphosphate; Animals; Hypoxanthine; Inosine; Kinetics; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Purine Nucleotides; Purines; Rats; Time Factors; Uric Acid; Xanthine

1998
Myocardial ischemic injury during cardio-pulmonary by-pass. Evaluation of purine compounds by capillary electrophoresis.
    Advances in experimental medicine and biology, 1998, Volume: 431

    Topics: Adenosine; Aged; Biopsy; Cardiomyopathies; Cardiopulmonary Bypass; Electrophoresis, Capillary; Heart Ventricles; Humans; Hypoxanthine; Inosine; Middle Aged; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Purine Nucleotides; Purines

1998
Different mechanism of myocardial nucleotide breakdown during normothermic and hypothermic ischemia.
    Advances in experimental medicine and biology, 1998, Volume: 431

    Topics: Adenosine; Animals; Heart Arrest, Induced; Hypoxanthine; In Vitro Techniques; Inosine; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Nucleotides; Rats; Temperature; Time Factors; Uric Acid; Xanthine

1998
Myocardial preconditioning produced by ischemia, hypoxia, and a KATP channel opener: effects on interstitial adenosine in dogs.
    Journal of molecular and cellular cardiology, 1998, Volume: 30, Issue:6

    Topics: Adenine Nucleotides; Adenosine; Animals; Benzopyrans; Dihydropyridines; Dogs; Extracellular Space; Hemodynamics; Hypoxanthine; Hypoxia; Inosine; Ischemic Preconditioning, Myocardial; Myocardial Infarction; Myocardial Ischemia; Potassium Channels; Uric Acid; Xanthine

1998
Endogenous adenosine reduces the occurrence of ischemia-induced ventricular fibrillation in rat heart.
    Journal of molecular and cellular cardiology, 1999, Volume: 31, Issue:1

    Topics: Adenine; Adenosine; Aminoimidazole Carboxamide; Animals; Caffeine; Creatine Kinase; Electrocardiography; Enzyme Inhibitors; Hypoxanthine; Inosine; Male; Myocardial Ischemia; Myocardium; Perfusion; Rats; Rats, Wistar; Reperfusion Injury; Ribonucleosides; Theophylline; Thioinosine; Thiophenes; Time Factors; Ventricular Fibrillation; Xanthines

1999
Urinary hypoxanthine and xanthine levels in acute coronary syndromes.
    International journal of clinical & laboratory research, 1999, Volume: 29, Issue:4

    Topics: Acute Disease; Adult; Aged; Angina, Unstable; Biomarkers; Blood Urea Nitrogen; Creatine; Female; Humans; Hypoxanthine; Male; Middle Aged; Myocardial Ischemia; Purines; Uric Acid; Xanthine

1999
Intrinsic A(1) adenosine receptor activation during ischemia or reperfusion improves recovery in mouse hearts.
    American journal of physiology. Heart and circulatory physiology, 2000, Volume: 279, Issue:5

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Creatine; Extracellular Space; Heart Function Tests; Heart Rate; Hypoxanthine; In Vitro Techniques; Inosine; Male; Mice; Mice, Inbred C57BL; Microdialysis; Myocardial Ischemia; Myocardium; Phosphocreatine; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Recovery of Function; Reperfusion; Reperfusion Injury; Xanthines

2000
Nucleoside transport inhibition in ischemic myocardium results in enhanced taurine efflux.
    European journal of pharmacology, 2001, Jan-05, Volume: 411, Issue:1-2

    Topics: Adenosine; Animals; Biological Transport; Dipyridamole; Hypoxanthine; Inosine; Lactates; Microdialysis; Myocardial Ischemia; Nucleosides; Pyruvic Acid; Swine; Taurine; Vasodilator Agents

2001
Myocardial metabolism and adaptation during extreme hemodilution in humans after coronary revascularization.
    Critical care medicine, 1992, Volume: 20, Issue:10

    Topics: Blood Transfusion, Autologous; Catheterization, Swan-Ganz; Coronary Artery Bypass; Electrocardiography; Hematocrit; Hemodilution; Hemodynamics; Hospitals, University; Humans; Hypoxanthine; Hypoxanthines; Intraoperative Complications; Lactates; Lactic Acid; Myocardial Ischemia; Oxygen Consumption; Prospective Studies

1992
Myocardial adenine nucleotide depletion within 1 h of acute coronary artery occlusion.
    Scandinavian journal of clinical and laboratory investigation, 1992, Volume: 52, Issue:7

    Topics: Adenine Nucleotides; Animals; Cats; Constriction; Coronary Vessels; Energy Metabolism; Hemodynamics; Hypoxanthine; Hypoxanthines; Inosine; Kinetics; Male; Myocardial Ischemia; Myocardium; Xanthine; Xanthines

1992
The nucleotide metabolism in lactate perfused hearts under ischaemic and reperfused conditions.
    Molecular and cellular biochemistry, 1992, Dec-02, Volume: 118, Issue:1

    Topics: Adenosine; Adenosine Triphosphate; Animals; Energy Metabolism; Glucose; Glycogen; Guanosine Triphosphate; Heart; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine; Inosine Monophosphate; Kinetics; Lactates; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Phosphocreatine; Pyruvates; Rats; Rats, Inbred Lew; Time Factors; Xanthine; Xanthines

1992