hypoxanthine has been researched along with Leukemia L 1210 in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (75.00) | 18.7374 |
| 1990's | 3 (18.75) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (6.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bloomer, LC; Patil, VD; Townsend, LB; Wise, DS; Wotring, LL | 1 |
| Bartier, WA; Chong, L; Ma, G; Tattersall, MH | 1 |
| Adamson, DJ; Bennett, LL; Brockman, RW; Rose, LM; Smithers, D | 1 |
| Cybulski, RL; Fry, DW; Goldman, ID | 1 |
| Samuels, LL; Straw, JA | 1 |
| Mackinnon, WB; Nott, SE; Piper, AA; Tattersall, MH | 1 |
| Plagemann, PG; Wohlhueter, RM | 1 |
| El Khadem, HS; Nelson, V; Sesselman, D; Whitten, BK | 1 |
| Francis, PR; Slowiaczek, P; Tattersall, MH; Taylor, IW | 1 |
| Chong, LK; Tattersall, MH | 1 |
| Kwok, JB; Tattersall, MH | 2 |
| Alison, DL; Calvert, AH; Harrap, KR; Jackman, AL | 1 |
| Allan, PW; Bennett, LL; Brockman, RW; Clayton, JD; Rose, LM; Shaddix, SC; Shealy, YF | 1 |
| Fairchild, CR; Maybaum, J; Straw, JA | 1 |
| Allan, PW; Bennett, LL; Comber, RN; Rose, LM; Secrist, JA | 1 |
16 other study(ies) available for hypoxanthine and Leukemia L 1210
| Article | Year |
|---|---|
Synthesis and biological activity of a novel adenosine analogue, 3-beta-D-ribofuranosylthieno[2,3-d]pyrimidin-4-one.
Topics: Adenosine; Adenosine Kinase; Animals; Antineoplastic Agents; Biotransformation; In Vitro Techniques; Leukemia L1210; Mice; Pyrimidine Nucleosides | 1985 |
Effects of extracellular purines on cytotoxicity of methotrexate.
Topics: Animals; Antimetabolites, Antineoplastic; Cell Survival; Culture Media, Conditioned; Deoxyribonucleotides; Dipyridamole; Drug Synergism; Hypoxanthine; Leukemia L1210; Methotrexate; Mice; Purines; Tumor Stem Cell Assay | 2010 |
Mode of action of 2-amino-6-chloro-1-deazapurine.
Topics: 2-Aminopurine; Adenine; AMP Deaminase; Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line; Cell Survival; Glycine; Humans; Hypoxanthine; Hypoxanthines; IMP Dehydrogenase; Laryngeal Neoplasms; Leukemia L1210; Macromolecular Substances; Mice; Nucleotides; Ribonucleotides; Structure-Activity Relationship | 1984 |
Approaches to the measurement of intracellular adenine and the discrimination between adenine transport and metabolism in L1210 leukemia cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Animals; Azides; Biological Transport; Glucose; Hypoxanthine; Hypoxanthines; Leukemia L1210; Mice; Phosphates; Temperature; Time Factors | 1982 |
Improved therapeutic index with high-dose methotrexate: comparison of thymidine-purine rescue with citrovorum factor rescue in mice.
Topics: Animals; Brain Neoplasms; Deoxycytidine; DNA Replication; Dose-Response Relationship, Drug; Hypoxanthine; Hypoxanthines; Inosine; Leucovorin; Leukemia L1210; Methotrexate; Mice; Thymidine; Thymine | 1984 |
Critical modulation by thymidine and hypoxanthine of sequential methotrexate-5-fluorouracil synergism in murine L1210 cells.
Topics: Animals; Cell Survival; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Hypoxanthine; Hypoxanthines; Kinetics; Leukemia L1210; Methotrexate; Mice; Thymidine | 1983 |
Nucleoside transport in cultured mammalian cells. Multiple forms with different sensitivity to inhibition by nitrobenzylthioinosine or hypoxanthine.
Topics: Animals; Biological Transport; Cell Line; Cricetinae; Cricetulus; Female; Hypoxanthine; Hypoxanthines; Inosine; Kinetics; L Cells; Leukemia L1210; Leukemia P388; Liver Neoplasms, Experimental; Lymphoma; Mice; Ovary; Rats; Thioinosine; Tritium; Uridine | 1984 |
Synthesis of hypoxanthine, guanine, and 6-thiopurine nucleosides of 6-deoxy-D-allofuranose.
Topics: Animals; Deoxyguanosine; Guanine; Hypoxanthine; Hypoxanthines; Indicators and Reagents; Inosine; Leukemia L1210; Magnetic Resonance Spectroscopy; Mice; Nucleosides; Purine Nucleosides; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Thionucleosides | 1983 |
Purine modulation of methotrexate cytotoxicity in mammalian cell lines.
Topics: Animals; Cell Line; Cell Survival; Deoxyribonucleotides; Humans; Hypoxanthine; Hypoxanthines; Kinetics; Leukemia L1210; Leukemia, Lymphoid; Melanoma; Methotrexate; Mice; Purines | 1982 |
5,10-Dideazatetrahydrofolic acid reduces toxicity and deoxyadenosine triphosphate pool, expansion in cultured L1210 cells treated with inhibitors of thymidylate synthase.
Topics: Animals; Cell Survival; Deoxyadenine Nucleotides; Drug Interactions; Floxuridine; Folic Acid; Hypoxanthine; Hypoxanthines; Leukemia L1210; Quinazolines; Tetrahydrofolates; Thiophenes; Thymidylate Synthase; Tumor Cells, Cultured | 1995 |
DNA fragmentation, dATP pool elevation and potentiation of antifolate cytotoxicity in L1210 cells by hypoxanthine.
Topics: Animals; Deoxyadenine Nucleotides; DNA Damage; Drug Synergism; Folic Acid; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Leukemia L1210; Methotrexate; Mice; Tumor Cells, Cultured | 1992 |
Inhibition of 2-desamino-2-methyl-10-propagyl-5,8-dideazafolic acid cytotoxicity by 5,10-dideazatetrahydrofolate in L1210 cells with decrease in DNA fragmentation and deoxyadenosine triphosphate pools.
Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Survival; Deoxyadenine Nucleotides; DNA, Neoplasm; Drug Antagonism; Folic Acid; Folic Acid Antagonists; Hypoxanthine; Hypoxanthines; Leukemia L1210; Mice; Tetrahydrofolates; Thymine Nucleotides; Tumor Cells, Cultured | 1991 |
Increased thymidylate synthase in L1210 cells possessing acquired resistance to N10-propargyl-5,8-dideazafolic acid (CB3717): development, characterization, and cross-resistance studies.
Topics: Animals; Antineoplastic Agents; Cells, Cultured; Deoxyuridine; Drug Resistance; Floxuridine; Fluorouracil; Folic Acid; Folic Acid Antagonists; Hypoxanthine; Hypoxanthines; Kinetics; Leukemia L1210; Mice; Quinazolines; Thymidylate Synthase; Tritium | 1986 |
Inhibition of utilization of hypoxanthine and guanine in cells treated with the carbocyclic analog of adenosine. Phosphates of carbocyclic nucleoside analogs as inhibitors of hypoxanthine (guanine) phosphoribosyltransferase.
Topics: Adenosine; Animals; Carcinoma, Squamous Cell; Cell Line; Coformycin; Colonic Neoplasms; Cyclic GMP; Cyclic IMP; Guanine; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Inosine Nucleotides; Kinetics; Leukemia L1210; Mice; Pentosyltransferases; Ribonucleotides | 1985 |
Enhanced cytotoxicity with methotrexate in conjunction with hypoxanthine in L1210 cells in culture.
Topics: Animals; Cell Cycle; Cell Survival; Cells, Cultured; Chromosomes; DNA, Neoplasm; Drug Synergism; Flow Cytometry; Hypoxanthine; Hypoxanthines; Leukemia L1210; Methotrexate; RNA, Neoplasm | 1988 |
Differences in the metabolism and metabolic effects of the carbocyclic adenosine analogs, neplanocin A and aristeromycin.
Topics: Adenosine; Adenosine Deaminase; Adenosine Triphosphate; AMP Deaminase; Animals; Cell Division; Cell Line; Guanine; Guanosine Triphosphate; Hypoxanthine; Hypoxanthines; Isomerism; Kinetics; Leukemia L1210; Mice | 1986 |