hypoxanthine has been researched along with Hyperuricemia in 23 studies
*Hyperuricemia: Excessive URIC ACID or urate in blood as defined by its solubility in plasma at 37 degrees C; greater than 0.42mmol per liter (7.0mg/dL) in men or 0.36mmol per liter (6.0mg/dL) in women. This condition is caused by overproduction of uric acid or impaired renal clearance. Hyperuricemia can be acquired, drug-induced or genetically determined (LESCH-NYHAN SYNDROME). It is associated with HYPERTENSION and GOUT. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (26.09) | 29.6817 |
| 2010's | 11 (47.83) | 24.3611 |
| 2020's | 6 (26.09) | 2.80 |
| Authors | Studies |
|---|---|
| Bertuzzi, F; Poje, M; Poje, N; Rocić, B; Vucić-Lovrencić, M | 1 |
| Cai, J; Chen, J; Gao, C; Jiang, L; Liu, Y; Su, Z; Wei, L; Wu, X; Wu, Y; Xiao, S; Xu, L | 1 |
| Chen, J; Huang, Z; Jiang, L; Li, Y; Lin, G; Lin, Z; Liu, Y; Mai, L; Su, Z; Xie, J; Xu, L; Yu, Q | 1 |
| Chen, Y; Liu, T; Yang, Z; Yuan, F; Zhang, L; Zhang, S; Zhou, X; Zhuang, J | 1 |
| Furuhashi, M; Higashiura, Y; Koyama, M; Matsumoto, M; Miura, T; Moniwa, N; Murase, T; Nakamura, T; Ohnishi, H; Saitoh, S; Sakai, A; Shimamoto, K; Tanaka, M | 1 |
| Calixto-Tlacomulco, S; Delgado-Coello, B; Gutiérrez-Vidal, R; Mas-Oliva, J; Toledo-Ibelles, P | 1 |
| Hu, N; Lin, Y; Wang, J; Wang, S; Wang, X; Zhang, B; Zhao, X; Zhou, X | 1 |
| Gao, LH; Li, L; Lin, H; Niu, Y; Xiong, W; Zhou, Y; Zhu, H; Zou, CG | 1 |
| Chen, D; Chen, S; Deng, C; Diao, X; Li, D; Li, M; Liang, D; Xie, Y; Yong, T; Zuo, D | 1 |
| Baldini, E; Bernardini, G; Jacomelli, G; Micheli, V; Mugnaini, C; Santucci, A | 1 |
| Deng, B; Deng, M; Fei, X; Huang, Z; Wang, Y; Ye, L | 1 |
| Dong, Y; Liu, J; Zhao, W; Zhou, H; Zhou, Z | 1 |
| Kostalova, E; Musalkova, D; Pavelka, K; Stiburkova, B; Vlaskova, H | 1 |
| Iseki, K; Kaneko, C; Kobayashi, M; Koizumi, T; Kuwayama, K; Ogura, J; Sasaki, S; Takaya, A; Takeno, R; Tsujimoto, T; Yabe, K; Yamaguchi, H | 1 |
| Chen, D; Chen, S; Feng, D; Jiao, C; Shuai, O; Su, J; Xie, Y; Yong, T; Zhang, M | 1 |
| Hamada, T; Hisatome, I; Igawa, O; Mizuta, E; Shigemasa, C | 1 |
| Butler, K; Teng, R | 1 |
| Fu, HW; Hou, CW; Hung, HF; Jeng, KC; Lee, YC | 1 |
| Hosoya, T; Ohno, I; Saikawa, H; Uetake, D | 1 |
| Suzuki, S; Yoneyama, Y | 1 |
| de Bont, JM; Pieters, R | 1 |
| Moriwaki, Y; Takahashi, S; Yamamoto, T | 1 |
| Hisatome, I; Igawa, O; Mizuta, E | 1 |
5 review(s) available for hypoxanthine and Hyperuricemia
| Article | Year |
|---|---|
[Calcium antagonists: current and future applications based on new evidence. The mechanisms on lowering serum uric acid level by calcium channel blockers].
Topics: Anaerobiosis; Calcium Channel Blockers; Cardiovascular Diseases; Depression, Chemical; Gout; Humans; Hypertension; Hyperuricemia; Hypoxanthine; Kidney Diseases; Muscle, Skeletal; Risk Factors; Uric Acid | 2010 |
[Purine metabolism in patients with renal failure].
Topics: Allopurinol; Antimetabolites; Glomerulonephritis; Humans; Hyperuricemia; Hypoxanthine; Kidney; Kidney Failure, Chronic; Purines; Renal Dialysis; Uric Acid; Xanthine | 2004 |
Management of hyperuricemia with rasburicase review.
Topics: Allopurinol; Antimetabolites; Clinical Trials as Topic; Cost-Benefit Analysis; Free Radical Scavengers; Humans; Hyperuricemia; Hypoxanthine; Time Factors; Tumor Lysis Syndrome; Urate Oxidase; Uric Acid; Xanthine Oxidase | 2004 |
Effect of ethanol on metabolism of purine bases (hypoxanthine, xanthine, and uric acid).
Topics: Acetyl Coenzyme A; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Ethanol; Humans; Hyperuricemia; Hypoxanthine; Lactic Acid; NAD; Oxidation-Reduction; Uric Acid; Xanthine; Xanthine Dehydrogenase | 2005 |
[Idiopathic hyperuricemia with overproduction of uric acid].
Topics: Antihypertensive Agents; Gout; Humans; Hypertension; Hyperuricemia; Hypoxanthine; Muscle, Skeletal; Purines; Uric Acid | 2008 |
1 trial(s) available for hypoxanthine and Hyperuricemia
| Article | Year |
|---|---|
Evaluation and characterization of the effects of ticagrelor on serum and urinary uric acid in healthy volunteers.
Topics: Adenosine; Adult; Cross-Over Studies; Humans; Hyperuricemia; Hypoxanthine; Male; Middle Aged; Purinergic P2Y Receptor Antagonists; Ticagrelor; Time Factors; Uric Acid; Xanthine | 2012 |
17 other study(ies) available for hypoxanthine and Hyperuricemia
| Article | Year |
|---|---|
Uric acid may inhibit glucose-induced insulin secretion via binding to an essential arginine residue in rat pancreatic beta-cells.
Topics: Animals; Arginine; Glucose; Hyperuricemia; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Protein Binding; Rats; Structure-Activity Relationship; Uric Acid | 2005 |
Topics: Acute Kidney Injury; Animals; Animals, Outbred Strains; Carrier Proteins; Cytokines; Dietary Supplements; Fatty Acids; Hyperuricemia; Hypoxanthine; Kelch-Like ECH-Associated Protein 1; Kidney; Lythraceae; Male; Mice; NF-E2-Related Factor 2; NLR Family, Pyrin Domain-Containing 3 Protein; Organic Anion Transporters; Oxidative Stress; Oxonic Acid; Plant Oils; Reactive Oxygen Species; Seeds; Signal Transduction; Thioredoxins; Uric Acid | 2021 |
Berberrubine attenuates potassium oxonate- and hypoxanthine-induced hyperuricemia by regulating urate transporters and JAK2/STAT3 signaling pathway.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; Berberine; Blood Urea Nitrogen; Chemical and Drug Induced Liver Injury; Creatinine; Cytokines; Disease Models, Animal; Glucose Transport Proteins, Facilitative; Hyperuricemia; Hypoxanthine; Janus Kinase 2; Kidney Diseases; Male; Mice; Organic Anion Transport Protein 1; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Oxonic Acid; Protective Agents; Signal Transduction; STAT3 Transcription Factor; Uric Acid; Xanthine Oxidase | 2021 |
Astaxanthin attenuated hyperuricemia and kidney inflammation by inhibiting uric acid synthesis and the NF-κ B/NLRP3 signaling pathways in potassium oxonate and hypoxanthine-induced hyperuricemia mice.
Topics: Animals; Antioxidants; Hyperuricemia; Hypoxanthine; Inflammation; Kidney; Male; Mice; Mice, Inbred ICR; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Oxonic Acid; Signal Transduction; Transcription Factor RelA; Uric Acid; Xanthine Oxidase; Xanthophylls | 2021 |
Differential regulation of hypoxanthine and xanthine by obesity in a general population.
Topics: Adipose Tissue; Aged; Alanine Transaminase; Biomarkers; Body Mass Index; Enzyme Inhibitors; Female; Humans; Hyperuricemia; Hypoxanthine; Japan; Liver; Male; Middle Aged; Obesity; Regression Analysis; Signal Transduction; Triglycerides; Xanthine; Xanthine Dehydrogenase | 2020 |
Hepatic Accumulation of Hypoxanthine: A Link Between Hyperuricemia and Nonalcoholic Fatty Liver Disease.
Topics: Animals; Hydrogen Peroxide; Hyperuricemia; Hypoxanthine; Liver; Male; Non-alcoholic Fatty Liver Disease; Rabbits | 2021 |
Chlorogenic acid supplementation ameliorates hyperuricemia, relieves renal inflammation, and modulates intestinal homeostasis.
Topics: Animals; Blood Urea Nitrogen; Chlorogenic Acid; Creatinine; Dietary Supplements; Gastrointestinal Microbiome; Homeostasis; Hyperuricemia; Hypoxanthine; Inflammation; Interleukin-1beta; Intestines; Kidney; Lipopolysaccharides; Male; Mice; Myeloid Differentiation Factor 88; NF-kappa B; Oxonic Acid; Signal Transduction; Toll-Like Receptor 4; Uric Acid; Xanthine Oxidase | 2021 |
Inhibition of 3,5,2',4'-Tetrahydroxychalcone on Production of Uric Acid in Hypoxanthine-Induced Hyperuricemic Mice.
Topics: Animals; Chalcones; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperuricemia; Hypoxanthine; Liver; Male; Mice, Inbred Strains; Purines; Uric Acid; Xanthine Dehydrogenase; Xanthine Oxidase | 2018 |
Anti-Hyperuricemic Effect of 2-Hydroxy-4-methoxy-benzophenone-5-sulfonic Acid in Hyperuricemic Mice through XOD.
Topics: Animals; Benzophenones; Body Weight; Gene Expression Regulation; Glucose Transport Proteins, Facilitative; Humans; Hyperuricemia; Hypoxanthine; Kidney; Mice; Molecular Docking Simulation; Organic Anion Transport Protein 1; Oxonic Acid; Spleen; Thymus Gland; Xanthine Oxidase | 2018 |
Inhibiting PNP for the therapy of hyperuricemia in Lesch-Nyhan disease: Preliminary in vitro studies with analogues of immucillin-G.
Topics: Allopurinol; Cells, Cultured; Enzyme Inhibitors; Humans; Hyperuricemia; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Lesch-Nyhan Syndrome; Purine-Nucleoside Phosphorylase; Purines; Pyrimidinones; Pyrroles; Reproducibility of Results; Uric Acid; Xanthine | 2019 |
Study on the diagnosis of gout with xanthine and hypoxanthine.
Topics: Blood Chemical Analysis; Chromatography, High Pressure Liquid; Gout; Humans; Hyperuricemia; Hypoxanthine; Limit of Detection; Male; Reproducibility of Results; Uric Acid; Xanthine | 2019 |
MiR-143-3p directly targets GLUT9 to reduce uric acid reabsorption and inflammatory response of renal tubular epithelial cells.
Topics: Animals; Base Sequence; Case-Control Studies; Chemokine CCL2; Disease Models, Animal; Gene Expression Regulation; Glucose Transport Proteins, Facilitative; Humans; Hyperuricemia; Hypoxanthine; Inflammation; Interleukin-1beta; Kidney Cortex; Male; Mice; Mice, Inbred C57BL; MicroRNAs; Oligonucleotide Array Sequence Analysis; Organic Anion Transporters; Organic Cation Transport Proteins; Oxonic Acid; Renal Reabsorption; Signal Transduction; Uric Acid | 2019 |
Hyperuricemia and gout due to deficiency of hypoxanthine-guanine phosphoribosyltransferase in female carriers: New insight to differential diagnosis.
Topics: Adult; Child; Diagnosis, Differential; Female; Gout; Heterozygote; Humans; Hyperuricemia; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Infant, Newborn; Male; Mutation; Pedigree; Xanthine | 2015 |
Reactive oxygen species derived from xanthine oxidase interrupt dimerization of breast cancer resistance protein, resulting in suppression of uric acid excretion to the intestinal lumen.
Topics: Aging; Allopurinol; Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Caco-2 Cells; Dimerization; Enzyme Induction; Enzyme Inhibitors; Gout Suppressants; Humans; Hyperuricemia; Hypoxanthine; Ileum; Inosine; Intestinal Elimination; Intestinal Mucosa; Male; Mitochondria; Neoplasm Proteins; Rats, Wistar; Reactive Oxygen Species; Uric Acid; Xanthine Oxidase | 2015 |
Actions of water extract from Cordyceps militaris in hyperuricemic mice induced by potassium oxonate combined with hypoxanthine.
Topics: Animals; Blood Urea Nitrogen; Cordyceps; Creatinine; Dose-Response Relationship, Drug; Hyperuricemia; Hypoxanthine; Kidney Function Tests; Male; Mice; Oxonic Acid; Plant Extracts; Water | 2016 |
Longan seed extract reduces hyperuricemia via modulating urate transporters and suppressing xanthine oxidase activity.
Topics: Allopurinol; Animals; Glucose Transporter Type 1; Gout; Gout Suppressants; Hyperuricemia; Hypoxanthine; Kidney; Liver; Male; Monosaccharide Transport Proteins; Oxonic Acid; Phytotherapy; Plant Extracts; Polyphenols; Rats; Rats, Sprague-Dawley; Sapindaceae; Seeds; Uric Acid; Xanthine Oxidase | 2012 |
Maternal plasma hypoxanthine levels in nonpreeclamptic twin pregnancies.
Topics: Adenosine; Adult; Female; Humans; Hyperuricemia; Hypoxanthine; Pregnancy; Pregnancy Complications; Pregnancy Trimester, Third; Pregnancy, Multiple; Retrospective Studies; Twins; Uric Acid | 2004 |