hypoxanthine and Disease Models, Animal

hypoxanthine has been researched along with Disease Models, Animal in 42 studies

Research

Studies (42)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (4.76)	18.7374
1990's	10 (23.81)	18.2507
2000's	14 (33.33)	29.6817
2010's	14 (33.33)	24.3611
2020's	2 (4.76)	2.80

Authors

Authors	Studies
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV	1
Chen, J; Huang, Z; Jiang, L; Li, Y; Lin, G; Lin, Z; Liu, Y; Mai, L; Su, Z; Xie, J; Xu, L; Yu, Q	1
Gao, LH; Li, L; Lin, H; Niu, Y; Xiong, W; Zhou, Y; Zhu, H; Zou, CG	1
Feng, H; Li, F; Li, R; Liu, X; Ma, K; Mu, N; Qu, J; Tan, L; Wang, S; Yang, C; Zhao, H	1
Caldana, E; Cassani, B; Castelli, A; Ficara, F; Menale, C; Muggeo, S; Paulis, M; Recordati, C; Scanziani, E; Strina, D; Susani, L; Vezzoni, P; Villa, A	1
Dong, Y; Liu, J; Zhao, W; Zhou, H; Zhou, Z	1
Brueck, W; Burfeind, P; Hakroush, S; Jakubiczka-Smorag, J; Kumar, A; Metz, I; Reiss, J; Santamaria-Araujo, JA; Schwarz, G; Smorag, L	1
Agu, RU; Kolathuru, SS; Yeung, PK	1
Feltri, ML; Shin, D; Weinstock, NI; Wrabetz, L	1
Kuligowski, J; Pankratov, L; Parra-Llorca, A; Quintás, G; Sánchez-Illana, Á; Saugstad, OD; Solberg, R; Vento, M	1
Falk, DJ; Hudson, MB; McClung, JM; Nelson, WB; Powers, SK; Smuder, AJ; Whidden, MA	1
Finkel, T; Fujii, K; Iida, M; Matsumura, K; Noguchi, H; Ohtsubo, T; Rovira, II; Sakagami, K; Tsuruya, K	1
Biala, A; Eriksson, O; Finckenberg, P; Kaheinen, P; Lapatto, R; Lempiäinen, J; Louhelainen, M; Luft, FC; Martonen, E; Mattila, I; Merasto, S; Mervaala, E; Muller, DN; Oresic, M	1
Dai, W; Liang, X; Liu, X; Lv, Y; Yan, S; Yang, Y; Zhang, W	1
Contant, CF; Enblad, P; Goiny, M; Nilsson, P; Piper, I; Salci, K	1
Dong, W; Liu, S; Lu, F; Yao, L	1
Allen, RH; Beaudin, AE; Perry, CA; Stabler, SP; Stover, PJ	1
Byram, R; Jain, S; Jewett, MW; Rosa, PA; Sutchu, S	1
Barát, E; Huszár, E; Juhász-Nagy, A; Kékesi, V; Merkely, B; Nagy, A; Toma, I; Zima, E	1
Halliwell, B; Huang, SH; Jenner, A; Lim, KS; Tang, SY; Wang, H	1
Contant, C; Enblad, P; Goiny, M; Nilsson, P; Piper, I; Salci, K	1
Bettiol, E; Day, K; Evans, JE; Leliwa-Sytek, A; Orengo, JM; Rodriguez, A	1
Haglund, U; Hillered, L; Rasmussen, I; Ungerstedt, U	1
Oyasaeter, S; Rognum, TO; Rootwelt, T; Saugstad, OD; Stoltenberg, L	1
Melton, DW; Wu, CL	1
Bennet, L; Gnanakumaran, K; Green, LR; Hanson, MA; Mills, GA; Walker, V	1
Melton, DW; Redhead, NJ; Selfridge, J; Wu, CL	1
Cirak, B; Colak, A; Kiliç, A; Kilinç, K; Koçak, A; Konan, A; Nurlu, G	1
Feet, BA; Moen, A; Saugstad, OD; Yu, XO	1
Akman, HO; Inan, C; Kiliç, I; Kilinç, K; Kotiloğlu, E; Michl, J	1
Alston, TA	1
Goiny, M; Oldner, A; Rudehill, A; Sollevi, A; Ungerstedt, U	1
Bauer, A; Beger, HG; Gansauge, F; Nevalainen, T; Nüssler, AK; Poch, B; Rau, B; Schoenberg, MH	1
Aden, U; Berman, RF; Fredholm, BB; O'Connor, WT	1
Camp, DM; Harel, E; Juneau, PL; LeWitt, PA; Loeffler, DA	1
Kroppenstedt, SN; Stover, JF; Unterberg, AW	1
Araki, T; Murata, T; Power, GG; Sawa, R; Suzuki, S; Yoneyama, Y	1
Bjerner, T; Henze, A; Ronquist, G; Thelin, S; Waldenström, A; Wikström, G; Zemgulis, V	1
Chen, XG; Han, R; Li, LN; Li, Y; Yan, CH	1
Akdemir, H; Aşik, Z; Karaküçük, I; Koç, RK; Oktem, IS; Paşaoğlu, H	1
Fürst, W; Hallström, S; Lieners, C; Molnar, H; Redl, H; Schlag, G	1
Al-Jurf, AS; Berlinger, WG; Spector, R; Stene, RA	1

Reviews

1 review(s) available for hypoxanthine and Disease Models, Animal

Article	Year
Elevated hypoxanthine in endotoxic shock. Critical care medicine, 1999, Volume: 27, Issue:4 Topics: Animals; Bacteremia; Disease Models, Animal; Endotoxins; Hypoxanthine; Inflammation; Microdialysis; Oxygen Consumption; Sensitivity and Specificity; Shock, Septic; Swine	1999

Other Studies

41 other study(ies) available for hypoxanthine and Disease Models, Animal

Article	Year
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49 Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection	2020
Berberrubine attenuates potassium oxonate- and hypoxanthine-induced hyperuricemia by regulating urate transporters and JAK2/STAT3 signaling pathway. European journal of pharmacology, 2021, Dec-05, Volume: 912 Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; Berberine; Blood Urea Nitrogen; Chemical and Drug Induced Liver Injury; Creatinine; Cytokines; Disease Models, Animal; Glucose Transport Proteins, Facilitative; Hyperuricemia; Hypoxanthine; Janus Kinase 2; Kidney Diseases; Male; Mice; Organic Anion Transport Protein 1; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Oxonic Acid; Protective Agents; Signal Transduction; STAT3 Transcription Factor; Uric Acid; Xanthine Oxidase	2021
Inhibition of 3,5,2',4'-Tetrahydroxychalcone on Production of Uric Acid in Hypoxanthine-Induced Hyperuricemic Mice. Biological & pharmaceutical bulletin, 2018, Jan-01, Volume: 41, Issue:1 Topics: Animals; Chalcones; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperuricemia; Hypoxanthine; Liver; Male; Mice, Inbred Strains; Purines; Uric Acid; Xanthine Dehydrogenase; Xanthine Oxidase	2018
Cattle Encephalon Glycoside and Ignotin Reduce Early Brain Injury and Cognitive Dysfunction after Subarachnoid Hemorrhage in Rats. Neuroscience, 2018, 09-15, Volume: 388 Topics: Amino Acids; Animals; Apoptosis; Brain Injuries; Cognitive Dysfunction; Disease Models, Animal; Drug Combinations; Gangliosides; Hippocampus; Hypoxanthine; Male; Maze Learning; Neurons; Neuroprotective Agents; Nootropic Agents; Peptides; Random Allocation; Rats, Sprague-Dawley; Subarachnoid Hemorrhage	2018
Chromosome Transplantation: Correction of the Chronic Granulomatous Disease Defect in Mouse Induced Pluripotent Stem Cells. Stem cells (Dayton, Ohio), 2019, Volume: 37, Issue:7 Topics: Aminopterin; Animals; Base Sequence; Cell Differentiation; Chromosomes, Mammalian; Clone Cells; CRISPR-Cas Systems; Culture Media; Disease Models, Animal; Gene Editing; Genetic Therapy; Granulocytes; Granulomatous Disease, Chronic; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Induced Pluripotent Stem Cells; Male; Mice; NADPH Oxidase 2; Proof of Concept Study; Sequence Deletion; Thioguanine; Thymidine; X Chromosome	2019
MiR-143-3p directly targets GLUT9 to reduce uric acid reabsorption and inflammatory response of renal tubular epithelial cells. Biochemical and biophysical research communications, 2019, 09-24, Volume: 517, Issue:3 Topics: Animals; Base Sequence; Case-Control Studies; Chemokine CCL2; Disease Models, Animal; Gene Expression Regulation; Glucose Transport Proteins, Facilitative; Humans; Hyperuricemia; Hypoxanthine; Inflammation; Interleukin-1beta; Kidney Cortex; Male; Mice; Mice, Inbred C57BL; MicroRNAs; Oligonucleotide Array Sequence Analysis; Organic Anion Transporters; Organic Cation Transport Proteins; Oxonic Acid; Renal Reabsorption; Signal Transduction; Uric Acid	2019
Mouse model for molybdenum cofactor deficiency type B recapitulates the phenotype observed in molybdenum cofactor deficient patients. Human genetics, 2016, Volume: 135, Issue:7 Topics: Animals; Apoptosis; Carbon-Carbon Lyases; Coenzymes; Cysteine; Disease Models, Animal; Gene Expression; Humans; Hypoxanthine; Metal Metabolism, Inborn Errors; Metalloproteins; Mice; Mice, Knockout; Molybdenum Cofactors; Mutation; Nuclear Proteins; Phenotype; Pteridines; Xanthine	2016
Effect of Cardiovascular Injury on Catabolism of Adenosine and Adenosine 5-'Triphosphate in Systemic Blood in a Freely Moving Rat Model In Vivo. Drug metabolism letters, 2016, Volume: 10, Issue:3 Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cardiovascular Diseases; Disease Models, Animal; Hypoxanthine; Isoproterenol; Rats; Rats, Sprague-Dawley; Uric Acid	2016
Metabolic profiling reveals biochemical pathways and potential biomarkers associated with the pathogenesis of Krabbe disease. Journal of neuroscience research, 2016, Volume: 94, Issue:11 Topics: Age Factors; Amino Acids, Branched-Chain; Analysis of Variance; Animals; Animals, Newborn; Biomarkers; Catatonia; Chromatography, Liquid; Cohort Studies; Dementia; Disease Models, Animal; Galactosylceramidase; Glucose; Glucose-6-Phosphatase; Hypoxanthine; Mass Spectrometry; Mice; Mice, Inbred C57BL; Neurotransmitter Agents; Signal Transduction	2016
Plasma metabolite score correlates with Hypoxia time in a newly born piglet model for asphyxia. Redox biology, 2017, Volume: 12 Topics: Animals; Animals, Newborn; Asphyxia Neonatorum; Biomarkers; Choline; Disease Models, Animal; Female; Humans; Hypoxanthine; Hypoxia-Ischemia, Brain; Male; Severity of Illness Index; Swine	2017
Xanthine oxidase contributes to mechanical ventilation-induced diaphragmatic oxidative stress and contractile dysfunction. Journal of applied physiology (Bethesda, Md. : 1985), 2009, Volume: 106, Issue:2 Topics: Animals; Diaphragm; Disease Models, Animal; Electric Stimulation; Enzyme Inhibitors; Female; Hypoxanthine; Lipid Peroxidation; Muscle Contraction; Muscle Weakness; Muscular Atrophy; Oxidative Stress; Oxypurinol; Protein Carbonylation; Rats; Rats, Sprague-Dawley; Time Factors; Uric Acid; Ventilator-Induced Lung Injury; Xanthine; Xanthine Dehydrogenase; Xanthine Oxidase	2009
Xanthine oxidoreductase depletion induces renal interstitial fibrosis through aberrant lipid and purine accumulation in renal tubules. Hypertension (Dallas, Tex. : 1979), 2009, Volume: 54, Issue:4 Topics: Adipogenesis; Animals; Disease Models, Animal; Epithelial Cells; Female; Fibrosis; Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating); Hypoxanthine; Kidney Tubules; Lipid Metabolism; Lipogenesis; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nephritis, Interstitial; Oxidative Stress; Purines; Triglycerides; Xanthine; Xanthine Dehydrogenase	2009
Metabolomics in angiotensin II-induced cardiac hypertrophy. Hypertension (Dallas, Tex. : 1979), 2010, Volume: 55, Issue:2 Topics: Angiotensin II; Animals; Animals, Genetically Modified; Biomarkers; Cardiomegaly; Disease Models, Animal; Fatty Acids; Female; Humans; Hypoxanthine; Linoleic Acids; Male; Metabolomics; Mitochondria, Heart; Oxidative Stress; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Sirtuin 1; Survival Rate; Tetrazoles; Valine; Valsartan	2010
Metabolomic study of myocardial ischemia and intervention effects of Compound Danshen Tablets in rats using ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry. Journal of pharmaceutical and biomedical analysis, 2010, May-01, Volume: 52, Issue:1 Topics: Allantoin; Animals; Biomarkers; Cardiovascular Agents; Chromatography, Liquid; Disease Models, Animal; Drugs, Chinese Herbal; Hypoxanthine; Inosine; Least-Squares Analysis; Male; Metabolomics; Myocardial Ischemia; Principal Component Analysis; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Salvia miltiorrhiza; Spectrometry, Mass, Electrospray Ionization; Tablets; Xanthine	2010
Metabolic effects of a late hypotensive insult combined with reduced intracranial compliance following traumatic brain injury in the rat. Upsala journal of medical sciences, 2010, Volume: 115, Issue:4 Topics: Animals; Brain; Brain Edema; Brain Injuries; Disease Models, Animal; Glycerol; Hypotension; Hypoxanthine; Lactic Acid; Male; Pyruvic Acid; Random Allocation; Rats; Rats, Sprague-Dawley; Time Factors	2010
An improved acute gouty arthritis rat model and therapeutic effect of rhizoma Dioscoreae nipponicae on acute gouty arthritis based on the protein-chip methods. The American journal of Chinese medicine, 2012, Volume: 40, Issue:1 Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Arthritis, Gouty; Dioscorea; Disease Models, Animal; Gene Expression Regulation; Hypoxanthine; Inflammation; Male; Medicine, Chinese Traditional; Neuropilin-2; Phytotherapy; Plant Extracts; Protein Array Analysis; Rats; Rats, Wistar; Rhizome; Synovial Membrane; TNF-Related Apoptosis-Inducing Ligand; Uric Acid	2012
Maternal Mthfd1 disruption impairs fetal growth but does not cause neural tube defects in mice. The American journal of clinical nutrition, 2012, Volume: 95, Issue:4 Topics: Aminohydrolases; Animals; Choline; Choline Deficiency; Crosses, Genetic; Disease Models, Animal; Embryo Loss; Female; Fetal Growth Retardation; Folic Acid; Folic Acid Deficiency; Formate-Tetrahydrofolate Ligase; Genes, Lethal; Heterozygote; Homocysteine; Hypoxanthine; Maternal Nutritional Physiological Phenomena; Methylenetetrahydrofolate Dehydrogenase (NADP); Mice; Mice, Mutant Strains; Multienzyme Complexes; Mutagenesis, Insertional; Neural Tube Defects; Pregnancy	2012
Borrelia burgdorferi harbors a transport system essential for purine salvage and mammalian infection. Infection and immunity, 2012, Volume: 80, Issue:9 Topics: Adenine; Animals; Borrelia burgdorferi; Disease Models, Animal; Female; Guanine; Hypoxanthine; Lyme Disease; Membrane Transport Proteins; Mice; Mice, Inbred C3H; Plasmids; Virulence Factors	2012
Nitrogen oxide blockade does not aggravate the endothelin-1-induced myocardial ischemia and release of purine metabolites from the dog heart. Journal of cardiovascular pharmacology, 2004, Volume: 44 Suppl 1 Topics: Adaptation, Physiological; Adenosine; Animals; Disease Models, Animal; Dogs; Endothelin-1; Enzyme Inhibitors; Hemodynamics; Hypoxanthine; Inosine; Myocardial Ischemia; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pericardium; Purines	2004
Potential artifacts in the measurement of DNA deamination. Free radical biology & medicine, 2006, Jun-01, Volume: 40, Issue:11 Topics: Amination; Animals; Artifacts; Cattle; Chromatography, High Pressure Liquid; Disease Models, Animal; DNA; Gas Chromatography-Mass Spectrometry; Humans; Hydrolysis; Hypoxanthine; Jurkat Cells; Lipopolysaccharides; Nitric Oxide; Oxidative Stress; Rats; Sepsis; Xanthine	2006
Low intracranial compliance increases the impact of intracranial volume insults to the traumatized brain: a microdialysis study in a traumatic brain injury rodent model. Neurosurgery, 2006, Volume: 59, Issue:2 Topics: Animals; Biomarkers; Brain; Brain Chemistry; Brain Edema; Brain Injuries; Cell Membrane; Cerebral Hemorrhage, Traumatic; Compliance; Disease Models, Animal; Energy Metabolism; Extracellular Fluid; Glycerol; Hypoxanthine; Intracranial Hypertension; Lactic Acid; Male; Microdialysis; Nerve Degeneration; Rats; Rats, Sprague-Dawley; Skull	2006
Plasmodium-induced inflammation by uric acid. PLoS pathogens, 2008, Mar-07, Volume: 4, Issue:3 Topics: Animals; Culture Media, Conditioned; Dendritic Cells; Disease Models, Animal; Erythrocytes; Hypoxanthine; Inflammation; Mice; Mice, Inbred BALB C; Plasmodium; Plasmodium berghei; Plasmodium falciparum; Plasmodium yoelii; Schizonts; Tumor Necrosis Factor-alpha; Uric Acid; Xanthine	2008
Detection of liver ischemia using microdialysis during experimental peritonitis in pigs. Shock (Augusta, Ga.), 1994, Volume: 1, Issue:1 Topics: Acidosis, Lactic; Animals; Disease Models, Animal; Extracellular Space; Female; Hypoxanthine; Hypoxanthines; Ischemia; Lactates; Lactic Acid; Liver; Male; Microdialysis; Oxygen Consumption; Peritonitis; Shock, Septic; Swine	1994
Hypoxanthine, xanthine, and uric acid concentrations in plasma, cerebrospinal fluid, vitreous humor, and urine in piglets subjected to intermittent versus continuous hypoxemia. Pediatric research, 1993, Volume: 34, Issue:6 Topics: Animals; Animals, Newborn; Disease Models, Animal; Female; Humans; Hypoxanthine; Hypoxanthines; Hypoxia; Infant; Male; Sudden Infant Death; Swine; Uric Acid; Vitreous Body; Xanthine; Xanthines	1993
Production of a model for Lesch-Nyhan syndrome in hypoxanthine phosphoribosyltransferase-deficient mice. Nature genetics, 1993, Volume: 3, Issue:3 Topics: Adenine; Adenine Phosphoribosyltransferase; Animals; Brain; Caffeine; Cell Division; Cells, Cultured; Disease Models, Animal; Embryo, Mammalian; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Lesch-Nyhan Syndrome; Mice; Mice, Mutant Strains; Purines; Self-Injurious Behavior; Stem Cells; Thymidine	1993
Effects of hypoxia on urinary organic acid and hypoxanthine excretion in fetal sheep. Pediatric research, 1996, Volume: 40, Issue:2 Topics: Animals; Asphyxia Neonatorum; Blood Gas Analysis; Blood Pressure; Carboxylic Acids; Disease Models, Animal; Embryonic and Fetal Development; Female; Gas Chromatography-Mass Spectrometry; Gestational Age; Heart Rate, Fetal; Humans; Hydrogen-Ion Concentration; Hypoxanthine; Hypoxia; Infant, Newborn; Lactic Acid; Pregnancy; Sheep	1996
Mice with adenine phosphoribosyltransferase deficiency develop fatal 2,8-dihydroxyadenine lithiasis. Human gene therapy, 1996, Aug-20, Volume: 7, Issue:13 Topics: Adenine; Adenine Phosphoribosyltransferase; Alleles; Allopurinol; Animals; Blotting, Southern; Chromatography, High Pressure Liquid; Cloning, Molecular; Crystallization; Disease Models, Animal; Genotype; Humans; Hypoxanthine; Kidney; Lesch-Nyhan Syndrome; Mice; Mice, Transgenic; Polymerase Chain Reaction; Purines	1996
A new model for tethered cord syndrome: a biochemical, electrophysiological, and electron microscopic study. Pediatric neurosurgery, 1997, Volume: 26, Issue:3 Topics: Animals; Axons; Disease Models, Animal; Evoked Potentials; Free Radicals; Guinea Pigs; Hypoxanthine; Lipid Peroxidation; Microscopy, Electron; Myelin Sheath; Spina Bifida Occulta; Spinal Cord	1997
Oxygen delivery and consumption in surfactant-depleted newborn piglets. Intensive care medicine, 1998, Volume: 24, Issue:4 Topics: Animals; Animals, Newborn; Blood Gas Analysis; Cardiac Output; Disease Models, Animal; Humans; Hypoxanthine; Infant, Newborn; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxygen; Oxygen Consumption; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Swine	1998
Antioxidant therapy of cobalt and vitamin E in hemosiderosis. The Journal of laboratory and clinical medicine, 1998, Volume: 132, Issue:2 Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Cobalt; Disease Models, Animal; Granuloma; Hemosiderosis; Hypoxanthine; Intestinal Mucosa; Iron; Lipid Peroxidation; Liver; Liver Diseases; Male; Peroxidase; Rats; Rats, Wistar; Spleen; Vitamin E	1998
Tissue hypoxanthine reflects gut vulnerability in porcine endotoxin shock. Critical care medicine, 1999, Volume: 27, Issue:4 Topics: Adipose Tissue; Animals; Bacteremia; Biomarkers; Disease Models, Animal; Disease Progression; Endotoxins; Hemodynamics; Hypoxanthine; Ileum; Liver; Lung; Microdialysis; Muscle, Skeletal; Prospective Studies; Reactive Oxygen Species; Shock, Septic; Swine; Tissue Distribution	1999
Pathophysiologic role of oxygen free radicals in acute pancreatitis: initiating event or mediator of tissue damage? Annals of surgery, 2000, Volume: 231, Issue:3 Topics: Animals; Disease Models, Animal; Free Radical Scavengers; Free Radicals; Hypoxanthine; Inflammation Mediators; Male; Oxidative Stress; Oxygen Consumption; Pancreatitis, Acute Necrotizing; Random Allocation; Rats; Rats, Wistar; Superoxide Dismutase; Xanthine Oxidase	2000
Evidence for increased dorsal hippocampal adenosine release and metabolism during pharmacologically induced seizures in rats. Brain research, 2000, Jul-28, Volume: 872, Issue:1-2 Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Bicuculline; Convulsants; Disease Models, Animal; Electroencephalography; Enzyme Inhibitors; Excitatory Amino Acid Agonists; GABA Antagonists; Guanosine; Hippocampus; Hypoxanthine; Inosine; Kainic Acid; Male; Microdialysis; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Seizures; Xanthine	2000
Purine-induced alterations of dopamine metabolism in rat pheochromocytoma PC12 cells. Brain research bulletin, 2000, Volume: 52, Issue:6 Topics: Adenine; Adenosine; Animals; Disease Models, Animal; Dopamine; Guanine; Guanosine; Hypoxanthine; Neostriatum; Neural Pathways; Neurons; Parkinson Disease; PC12 Cells; Purines; Rats; Substantia Nigra; Uric Acid; Xanthine	2000
Effects of dopamine on posttraumatic cerebral blood flow, brain edema, and cerebrospinal fluid glutamate and hypoxanthine concentrations. Critical care medicine, 2000, Volume: 28, Issue:12 Topics: Animals; Blood Flow Velocity; Blood Gas Analysis; Brain Edema; Brain Injuries; Cardiotonic Agents; Cerebrospinal Fluid; Cerebrovascular Circulation; Disease Models, Animal; Dopamine; Drug Evaluation, Preclinical; Glutamic Acid; Hypoxanthine; Laser-Doppler Flowmetry; Male; Random Allocation; Rats; Rats, Sprague-Dawley; Time Factors	2000
Changes in fetal plasma adenosine and xanthine concentrations during fetal asphyxia with maternal oxygen administration in ewes. The Tohoku journal of experimental medicine, 2000, Volume: 192, Issue:4 Topics: Adenosine; Animals; Asphyxia; Blood Gas Analysis; Blood Pressure; Disease Models, Animal; Female; Fetal Hypoxia; Heart Rate; Hypoxanthine; Oxygen; Sheep; Xanthine	2000
Energy-related metabolites during and after induced myocardial infarction with special emphasis on the reperfusion injury after extracorporeal circulation. Acta physiologica Scandinavica, 2001, Volume: 171, Issue:2 Topics: Adenosine; Animals; Chromatography, High Pressure Liquid; Dialysis Solutions; Disease Models, Animal; Energy Metabolism; Extracorporeal Circulation; Guanine; Heart Arrest, Induced; Hypoxanthine; Inosine; Lactic Acid; Microdialysis; Myocardial Infarction; Myocardium; Pyruvic Acid; Reperfusion Injury; Swine; Taurine	2001
Cancer chemopreventive activities of S-3-1, a synthetic derivative of danshinone. Journal of Asian natural products research, 2001, Volume: 3, Issue:1 Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Benzofurans; Bepridil; Biphenyl Compounds; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Croton Oil; Cysteine; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Epithelial Cells; Fibroblasts; Free Radical Scavengers; Hypoxanthine; In Vitro Techniques; Iron; Lipid Peroxidation; Lung; Male; Medicine, Chinese Traditional; Mice; Mice, Inbred ICR; Microsomes, Liver; Molecular Structure; Mutagens; Ornithine; Ornithine Decarboxylase; Papilloma; Pentetic Acid; Phenanthrenes; Picrates; Plants, Medicinal; Rats; Salmonella; Skin; Skin Neoplasms; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship; Xanthine Oxidase	2001
The effect of allopurinol on focal cerebral ischaemia: an experimental study in rabbits. Neurosurgical review, 2001, Volume: 24, Issue:2-3 Topics: Allopurinol; Animals; Blood Gas Analysis; Blood Glucose; Brain Ischemia; Chromatography, High Pressure Liquid; Disease Models, Animal; Free Radical Scavengers; Hematocrit; Hemoglobins; Hypoxanthine; Infarction, Middle Cerebral Artery; Rabbits; Uric Acid; Xanthine; Xanthine Oxidase	2001
Lipidperoxidation in a canine model of hypovolemic-traumatic shock. Progress in clinical and biological research, 1989, Volume: 308 Topics: Aldehydes; Animals; Disease Models, Animal; Dogs; Free Radicals; Hydrogen Peroxide; Hypoxanthine; Hypoxanthines; Lactates; Lactic Acid; Lipid Peroxidation; Malondialdehyde; Shock, Traumatic; Spectrometry, Fluorescence; Superoxides; Thiobarbiturates	1989
Plasma and cerebrospinal fluid nucleosides and oxypurines in acute liver failure. The Journal of laboratory and clinical medicine, 1987, Volume: 110, Issue:2 Topics: Animals; Chromatography, High Pressure Liquid; Disease Models, Animal; Guanosine; Hepatectomy; Hypoxanthine; Hypoxanthines; Inosine; Liver; Liver Diseases; Pyrimidine Nucleosides; Rabbits; Uric Acid	1987