hypoxanthine and Colonic Neoplasms

hypoxanthine has been researched along with Colonic Neoplasms in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19906 (54.55)18.7374
1990's4 (36.36)18.2507
2000's0 (0.00)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Senyavina, NV; Tonevitskaya, SA1
Houghton, JA; Houghton, PJ1
Findenig, G; Fritzer, M; Lhotka, C; Schön, HJ; Szekeres, T1
Lehman, NL; Moran, RG; Smith, SG1
Eguchi, H; Koh, YH; Park, YS; Suzuki, K; Taniguchi, N1
Nagai, M; Nakamura, H; Natsumeda, Y; Szekeres, T; Weber, G1
Allan, PW; Bennett, LL; Brockman, RW; Clayton, JD; Rose, LM; Shaddix, SC; Shealy, YF1
Bertino, JR; Handschumacher, RE; Sobrero, AF1
Fischer, PH; Pangallo, CA; Van Mouwerik, TJ; Willson, JK1
Caldarone, R; Leoncini, R; Lorenzi, M; Marinello, E; Vannoni, D1
Lönn, S; Lönn, U1

Other Studies

11 other study(ies) available for hypoxanthine and Colonic Neoplasms

ArticleYear
Effect of Hypoxanthine on Functional Activity of Nucleoside Transporters ENT1 and ENT2 in Caco-2 Polar Epithelial Intestinal Cells.
    Bulletin of experimental biology and medicine, 2015, Volume: 160, Issue:1

    Topics: Biological Transport; Cell Line, Tumor; Colon; Colonic Neoplasms; Epithelial Cells; Equilibrative Nucleoside Transporter 1; Equilibrative-Nucleoside Transporter 2; Gene Expression Regulation, Neoplastic; Humans; Hypoxanthine; Multigene Family; Neoplasm Proteins; Purines; Pyrimidines

2015
Combinations of 5-FU, hypoxanthine and allopurinol in chemotherapy for human colon adenocarcinoma xenografts.
    Cancer treatment reports, 1982, Volume: 66, Issue:5

    Topics: Adenocarcinoma; Allopurinol; Animals; Colonic Neoplasms; Drug Therapy, Combination; Fluorouracil; Humans; Hypoxanthine; Hypoxanthines; Male; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Transplantation, Heterologous

1982
[Synergistic cytotoxic effects of chemotherapy in colon tumor cells by simultaneous inhibition of de novo and salvage energy metabolism pathways].
    Wiener klinische Wochenschrift, 1994, Volume: 106, Issue:14

    Topics: Allopurinol; Antimetabolites, Antineoplastic; Benzamidines; Cell Line; Cell Survival; Colonic Neoplasms; Cytarabine; Deoxycytidine; Dose-Response Relationship, Drug; Drug Synergism; Gemcitabine; Humans; Hypoxanthine; Hypoxanthines; Ribavirin; Ribonucleotide Reductases; Tumor Cells, Cultured; Tumor Stem Cell Assay

1994
Cytotoxicity of antifolate inhibitors of thymidylate and purine synthesis to WiDr colonic carcinoma cells.
    Cancer research, 1993, Dec-01, Volume: 53, Issue:23

    Topics: Acyltransferases; Antineoplastic Agents; Cell Division; Cell Survival; Colonic Neoplasms; Folic Acid Antagonists; Humans; Hydroxymethyl and Formyl Transferases; Hypoxanthine; Hypoxanthines; Methotrexate; Phosphoribosylglycinamide Formyltransferase; Quinazolines; Tetrahydrofolates; Thiophenes; Thymidine; Thymidylate Synthase; Tumor Cells, Cultured

1993
Acceleration of adhesion of cancer cells and neutrophils to endothelial cells in the absence of de novo protein synthesis: possible implication for involvement of hydroxyl radicals.
    Biochemical and biophysical research communications, 1999, Apr-02, Volume: 257, Issue:1

    Topics: Catalase; Cell Adhesion; Cell Membrane; Chelating Agents; Colonic Neoplasms; Cycloheximide; Dactinomycin; Edetic Acid; Endothelium, Vascular; Humans; Hydrogen Peroxide; Hydroxyl Radical; Hypoxanthine; Neutrophils; Nitrates; Protein Biosynthesis; Reactive Oxygen Species; Superoxide Dismutase; Tumor Cells, Cultured; Xanthine Oxidase

1999
Regulation of GTP biosynthesis.
    Advances in enzyme regulation, 1992, Volume: 32

    Topics: Animals; Cell Differentiation; Cell Division; Colonic Neoplasms; Evaluation Studies as Topic; GMP Reductase; Guanosine Monophosphate; Guanosine Triphosphate; Humans; Hypoxanthine; Hypoxanthines; IMP Dehydrogenase; Inosine Monophosphate; Leukemia, Promyelocytic, Acute; Liver Neoplasms, Experimental; NADH, NADPH Oxidoreductases; Ribavirin; Tumor Cells, Cultured

1992
Inhibition of utilization of hypoxanthine and guanine in cells treated with the carbocyclic analog of adenosine. Phosphates of carbocyclic nucleoside analogs as inhibitors of hypoxanthine (guanine) phosphoribosyltransferase.
    Molecular pharmacology, 1985, Volume: 27, Issue:6

    Topics: Adenosine; Animals; Carcinoma, Squamous Cell; Cell Line; Coformycin; Colonic Neoplasms; Cyclic GMP; Cyclic IMP; Guanine; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Inosine Nucleotides; Kinetics; Leukemia L1210; Mice; Pentosyltransferases; Ribonucleotides

1985
Highly selective drug combinations for human colon cancer cells resistant in vitro to 5-fluoro-2'-deoxyuridine.
    Cancer research, 1985, Volume: 45, Issue:7

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Biological Transport; Cell Line; Colonic Neoplasms; Drug Resistance; Floxuridine; Humans; Hypoxanthine; Hypoxanthines; Methotrexate; Nucleosides; Quinazolines; Thymidine

1985
Augmentation of methotrexate cytotoxicity in human colon cancer cells achieved through inhibition of thymidine salvage by dipyridamole.
    Biochemical pharmacology, 1987, Mar-15, Volume: 36, Issue:6

    Topics: Cell Line; Cell Survival; Colonic Neoplasms; Dipyridamole; Drug Synergism; Guanine; Humans; Hypoxanthine; Hypoxanthines; Methotrexate; Rectal Neoplasms; Thymidine; Thymine Nucleotides

1987
The determination of urinary oxypurines as markers of gastrointestinal tumors.
    Tumori, 1987, Jun-30, Volume: 73, Issue:3

    Topics: Adult; Aged; Carcinoembryonic Antigen; Chromatography, High Pressure Liquid; Colonic Neoplasms; Female; Gastrointestinal Neoplasms; Humans; Hypoxanthine; Hypoxanthines; Male; Middle Aged; Rectal Neoplasms; Stomach Neoplasms; Xanthine; Xanthines

1987
The increased cytotoxicity in colon adenocarcinoma of methotrexate-5-fluorouracil is not associated with increased induction of lesions in DNA by 5-fluorouracil.
    Biochemical pharmacology, 1986, Jan-15, Volume: 35, Issue:2

    Topics: Adenocarcinoma; Cell Division; Cell Survival; Cells, Cultured; Colonic Neoplasms; DNA, Neoplasm; Drug Administration Schedule; Drug Interactions; Fluorouracil; Humans; Hypoxanthine; Hypoxanthines; Methotrexate

1986