hypoxanthine and Brain Ischemia

hypoxanthine has been researched along with Brain Ischemia in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19906 (21.43)18.7374
1990's14 (50.00)18.2507
2000's7 (25.00)29.6817
2010's1 (3.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andreescu, S; Erlichman, JS; Ganesana, M1
Geiger, JD; Haughey, NJ; Othman, T; Parkinson, FE; Sinclair, CJ1
Bracci, R; Buonocore, G; Perrone, S1
Engel, J; Fritz, T; Hempelmann, G; Kuhn, DF; Oehmke, MJ; Schirrmeister, D1
Kalous, P; Saugstad, OD; Solås, AB1
Brown, JK; Harkness, RA; Levin, SD1
Bachmann, B; Fritz, T; Hempelmann, G; Kuhn, DF; Oehmke, MJ1
Gidday, JM; Gonzales, ER; Kim, YB; Park, TS; Shah, AR1
Sciotti, VM; Van Wylen, DG1
Kalnovicová, T; Kuracka, L; Líska, B; Turcáni, P1
Carcillo, JA1
Barrier, L; Chalon, S; Guerraoui, A; Guilloteau, D; Huguet, F; Tallineau, C1
Kobayashi, T; Okada, Y; Yamada, T2
Hillered, L; Persson, L; Valtysson, J1
Hillered, L; Marklund, N; Nalmo, L; Ostman, B; Persson, L1
Andersson, J; Enblad, P; Fasth, KJ; Frykholm, P; Hillered, L; Långström, B; Persson, L; Silander, HC; Valtysson, J; Watanabe, Y1
Akdemir, H; Aşik, Z; Karaküçük, I; Koç, RK; Oktem, IS; Paşaoğlu, H1
Grabb, MC; Roche, FM; Sciotti, VM; Van Wylen, DG1
Cooke, RW; Jeffers, G; Russell, GA1
Gordon, EL; Hsu, SS; Meno, JR; Winn, HR; Zhou, JG1
Hillered, L; Kotwica, Z; Ungerstedt, U1
Breese, GR; Hunt, RD; Lundberg, C; McCown, TJ; Mueller, RA1
Carlsson, S; Hagberg, H; Sandberg, M; Skarphedinsson, JO; Thorén, P1
Andersson, P; Butcher, S; Hagberg, H; Hamberger, A; Lehmann, A; Sandberg, M1
Nihei, H1
Berne, RM; Park, TS; Rubio, R; Van Wylen, DG1
Betz, AL1

Reviews

1 review(s) available for hypoxanthine and Brain Ischemia

ArticleYear
New biomarkers of fetal-neonatal hypoxic stress.
    Acta paediatrica (Oslo, Norway : 1992). Supplement, 2002, Volume: 91, Issue:438

    Topics: Activins; Apgar Score; Asphyxia Neonatorum; Biomarkers; Brain Ischemia; Erythrocytes; Female; Fetal Blood; Free Radicals; Humans; Hypoxanthine; Infant, Newborn; Inhibin-beta Subunits; Iron; Male; Oxidative Stress; Prognosis; Risk Factors; Sensitivity and Specificity; Severity of Illness Index

2002

Trials

1 trial(s) available for hypoxanthine and Brain Ischemia

ArticleYear
Perioperative changes in cerebral ischemic markers in the cerebrospinal fluid after preoperative nimodipine treatment.
    Acta anaesthesiologica Scandinavica, 2003, Volume: 47, Issue:10

    Topics: Aged; Aged, 80 and over; Anesthesia, Spinal; Arthroplasty, Replacement, Hip; Biomarkers; Brain Ischemia; Calcium Channel Blockers; Cerebrospinal Fluid; Creatine Kinase; Double-Blind Method; Female; Humans; Hydrogen-Ion Concentration; Hypoxanthine; Infusions, Intravenous; Intraoperative Complications; Lactic Acid; Male; Neuroprotective Agents; Nimodipine; Phosphopyruvate Hydratase; Preoperative Care; Prospective Studies

2003

Other Studies

26 other study(ies) available for hypoxanthine and Brain Ischemia

ArticleYear
Real-time monitoring of superoxide accumulation and antioxidant activity in a brain slice model using an electrochemical cytochrome c biosensor.
    Free radical biology & medicine, 2012, Dec-15, Volume: 53, Issue:12

    Topics: Animals; Antioxidants; Biosensing Techniques; Brain Ischemia; Calibration; Cattle; Cell Hypoxia; Cerium; Cytochromes c; Electrochemical Techniques; Electrodes; Female; Hippocampus; Horses; Hypoxanthine; Immobilized Proteins; In Vitro Techniques; Male; Mice; Nanoparticles; Superoxide Dismutase; Superoxides; Voltage-Dependent Anion Channels; Xanthine Oxidase

2012
Differences between rat primary cortical neurons and astrocytes in purine release evoked by ischemic conditions.
    Neuropharmacology, 2002, Volume: 43, Issue:5

    Topics: Adenine Nucleotides; Adenosine Deaminase Inhibitors; Adenosine Kinase; Adenosine Triphosphate; Animals; Antimetabolites; Astrocytes; Brain Ischemia; Cells, Cultured; Cerebral Cortex; Chromatography, Thin Layer; Enzyme Inhibitors; Extracellular Space; Glucose; Hypoxanthine; Hypoxia-Ischemia, Brain; Inosine; Iodoacetates; Neurons; Purines; Rats; Sodium Cyanide

2002
Reoxygenation with 100 or 21% oxygen after cerebral hypoxemia-ischemia-hypercapnia in newborn piglets.
    Biology of the neonate, 2004, Volume: 85, Issue:2

    Topics: Amino Acids; Animals; Animals, Newborn; Blood Pressure; Brain; Brain Ischemia; Cerebral Cortex; Corpus Striatum; Dose-Response Relationship, Drug; Hypercapnia; Hypoxanthine; Hypoxia; Laser-Doppler Flowmetry; Microcirculation; Osmolar Concentration; Oxygen; Swine

2004
Cerebrospinal fluid hypoxanthine and xanthine concentrations as indicators of metabolic damage due to raised intracranial pressure in hydrocephalic children.
    Journal of neurology, neurosurgery, and psychiatry, 1984, Volume: 47, Issue:7

    Topics: Adolescent; Brain Diseases, Metabolic; Brain Ischemia; Child; Child, Preschool; Energy Metabolism; Humans; Hydrocephalus; Hypoxanthine; Hypoxanthines; Infant; Intracranial Pressure; Sleep, REM; Xanthine; Xanthines

1984
[A possible risk for geriatric risk patients caused by intraoperative disorder of cerebral energy utilization?].
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 1994, Volume: 29, Issue:8

    Topics: Aged; Anesthesia, Spinal; Blood-Brain Barrier; Brain Ischemia; Creatine Kinase; Dementia, Vascular; Energy Metabolism; Female; Hip Prosthesis; Humans; Hypoxanthine; Hypoxanthines; Intraoperative Complications; Lactates; Lactic Acid; Male; Middle Aged; Monitoring, Intraoperative; Neurocognitive Disorders; Neuroleptanalgesia; Phosphopyruvate Hydratase; Reoperation

1994
Effect of hypoglycemia on postischemic cortical blood flow, hypercapnic reactivity, and interstitial adenosine concentration.
    Journal of neurosurgery, 1994, Volume: 81, Issue:6

    Topics: Adenosine; Animals; Animals, Newborn; Blood Pressure; Brain Ischemia; Carbon Dioxide; Cerebral Cortex; Cerebrovascular Circulation; Extracellular Space; Hypercapnia; Hypoglycemia; Hypoxanthine; Hypoxanthines; Inosine; Swine; Xanthine; Xanthines

1994
Attenuation of ischemia-induced extracellular adenosine accumulation by homocysteine.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1993, Volume: 13, Issue:2

    Topics: Adenosine; Analysis of Variance; Animals; Brain; Brain Ischemia; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Extracellular Space; Homocysteine; Hypoxanthine; Hypoxanthines; Inosine; Male; Rats; Rats, Wistar; S-Adenosylhomocysteine

1993
HPLC method for measurement of purine nucleotide degradation products in cerebrospinal fluid.
    Clinical chemistry, 1996, Volume: 42, Issue:5

    Topics: Adult; Brain Ischemia; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Hypoxanthine; Hypoxanthines; Intervertebral Disc Displacement; Middle Aged; Multiple Sclerosis; Nervous System Diseases; Purine Nucleotides; Reference Values; Subarachnoid Hemorrhage; Uric Acid; Xanthine; Xanthines

1996
100% oxygen in the delivery room is just fine, for now.
    Critical care medicine, 1997, Volume: 25, Issue:8

    Topics: Animals; Brain Chemistry; Brain Ischemia; Hypoxanthine; Oxygen Inhalation Therapy; Swine

1997
Changes in excitatory amino acid levels and tissue energy metabolites of neonate rat brain after hypoxia and hypoxia-ischemia.
    Neuroscience letters, 1998, Jan-09, Volume: 240, Issue:2

    Topics: Animals; Animals, Newborn; Aspartic Acid; Brain; Brain Ischemia; Energy Metabolism; Excitatory Amino Acids; Glutamic Acid; Hypoxanthine; Hypoxia; Malondialdehyde; Rats; Rats, Wistar; Xanthine

1998
The levels of adenosine and its metabolites in the guinea pig and rat brain during complete ischemia-in vivo study.
    Brain research, 1998, Mar-23, Volume: 787, Issue:2

    Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Brain; Brain Chemistry; Brain Ischemia; Chromatography, High Pressure Liquid; Dyneins; Enzyme Inhibitors; Guinea Pigs; Hypoxanthine; Inosine; Male; Microwaves; Rats; Rats, Wistar; Spectrophotometry, Ultraviolet; Tissue Fixation

1998
The effects of simulated ischemia on the levels of adenosine and its metabolites in slices of cerebellum, superior colliculus and hippocampus in the guinea pig-in vitro study.
    Brain research, 1998, Mar-23, Volume: 787, Issue:2

    Topics: Adenosine; Animals; Brain Chemistry; Brain Ischemia; Cerebellum; Guinea Pigs; Hippocampus; Hypoxanthine; In Vitro Techniques; Inosine; Male; Microwaves; Superior Colliculi

1998
Extracellular ischaemia markers in repeated global ischaemia and secondary hypoxaemia monitored by microdialysis in rat brain.
    Acta neurochirurgica, 1998, Volume: 140, Issue:4

    Topics: Animals; Brain Ischemia; Cerebral Cortex; Electroencephalography; Energy Metabolism; Extracellular Space; Hypoxanthine; Hypoxia, Brain; Inosine; Ischemic Attack, Transient; Lactic Acid; Male; Microdialysis; Monitoring, Physiologic; Pyruvic Acid; Rats; Rats, Sprague-Dawley

1998
Hypoxanthine, uric acid and allantoin as indicators of in vivo free radical reactions. Description of a HPLC method and human brain microdialysis data.
    Acta neurochirurgica, 2000, Volume: 142, Issue:10

    Topics: Allantoin; Biomarkers; Brain Ischemia; Chromatography, High Pressure Liquid; Female; Free Radicals; Humans; Hypoxanthine; Microdialysis; Middle Aged; Reactive Oxygen Species; Subarachnoid Hemorrhage; Uric Acid

2000
Middle cerebral artery occlusion and reperfusion in primates monitored by microdialysis and sequential positron emission tomography.
    Stroke, 2001, Volume: 32, Issue:7

    Topics: Animals; Brain; Brain Ischemia; Cerebrovascular Circulation; Glutamic Acid; Hypoxanthine; Infarction, Middle Cerebral Artery; Lactic Acid; Macaca mulatta; Microdialysis; Oxygen Consumption; Pyruvic Acid; Reperfusion Injury; Tomography, Emission-Computed

2001
The effect of allopurinol on focal cerebral ischaemia: an experimental study in rabbits.
    Neurosurgical review, 2001, Volume: 24, Issue:2-3

    Topics: Allopurinol; Animals; Blood Gas Analysis; Blood Glucose; Brain Ischemia; Chromatography, High Pressure Liquid; Disease Models, Animal; Free Radical Scavengers; Hematocrit; Hemoglobins; Hypoxanthine; Infarction, Middle Cerebral Artery; Rabbits; Uric Acid; Xanthine; Xanthine Oxidase

2001
Adenosine receptor blockade augments interstitial fluid levels of excitatory amino acids during cerebral ischemia.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1992, Volume: 12, Issue:4

    Topics: Animals; Aspartic Acid; Brain Ischemia; Cerebrovascular Circulation; Glutamates; Glutamic Acid; Hypoxanthine; Hypoxanthines; Male; Neurotoxins; Purinergic Antagonists; Rats; Rats, Inbred Strains; Theophylline; Xanthine; Xanthines

1992
Plasma hypoxanthine: a marker for hypoxic-ischaemic induced periventricular leucomalacia?
    Archives of disease in childhood, 1992, Volume: 67, Issue:4 Spec No

    Topics: Biomarkers; Brain Ischemia; Chromatography, High Pressure Liquid; Fetal Blood; Humans; Hypoxanthine; Hypoxanthines; Hypoxia, Brain; Infant, Newborn; Intensive Care, Neonatal; Leukomalacia, Periventricular

1992
Influence of hyperglycemia on cerebral adenosine production during ischemia and reperfusion.
    The American journal of physiology, 1991, Volume: 261, Issue:2 Pt 2

    Topics: Adenine Nucleotides; Adenosine; Animals; Brain; Brain Ischemia; Hyperglycemia; Hypoxanthine; Hypoxanthines; Inosine; Male; Rats; Rats, Inbred Strains; Reperfusion

1991
Interstitial and cerebrospinal fluid levels of energy-related metabolites after middle cerebral artery occlusion in rats.
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1991, Volume: 191, Issue:3

    Topics: Animals; Arterial Occlusive Diseases; Brain Ischemia; Cerebral Arteries; Energy Metabolism; Extracellular Space; Hypoxanthine; Hypoxanthines; Inosine; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains

1991
Opposite alterations in cerebrospinal fluid uridine after severe cerebral ischemia or intrathecal blood injection.
    Cellular and molecular neurobiology, 1990, Volume: 10, Issue:3

    Topics: Animals; Blood; Brain Ischemia; Heart Arrest; Hypoglycemia; Hypoxanthine; Hypoxanthines; Hypoxia; Injections, Spinal; Insulin; Postmortem Changes; Potassium Chloride; Rats; Rats, Inbred Strains; Uridine; Xanthine; Xanthines

1990
Relative cerebral ischemia in SHR due to hypotensive hemorrhage: cerebral function, blood flow and extracellular levels of lactate and purine catabolites.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1989, Volume: 9, Issue:3

    Topics: Adenosine; Animals; Brain; Brain Ischemia; Cerebral Hemorrhage; Cerebrovascular Circulation; Extracellular Space; Hypertension; Hypotension; Hypoxanthine; Hypoxanthines; Inosine; Kinetics; Lactates; Lactic Acid; Male; Rats; Rats, Inbred SHR; Xanthine; Xanthines

1989
Blockade of N-methyl-D-aspartate-sensitive acidic amino acid receptors inhibits ischemia-induced accumulation of purine catabolites in the rat striatum.
    Neuroscience letters, 1986, Aug-04, Volume: 68, Issue:3

    Topics: 2-Amino-5-phosphonovalerate; Adenosine; Animals; Brain Ischemia; Corpus Striatum; Hypoxanthine; Hypoxanthines; Inosine; Male; Purines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Valine; Xanthine; Xanthines

1986
[Early changes of oxypurines in rat brain following focal cerebral ischemia].
    No to shinkei = Brain and nerve, 1988, Volume: 40, Issue:8

    Topics: Animals; Brain; Brain Ischemia; Chromatography, High Pressure Liquid; Hypoxanthine; Hypoxanthines; Male; Rats; Rats, Inbred Strains; Uric Acid; Xanthine; Xanthines

1988
Increases in cerebral interstitial fluid adenosine concentration during hypoxia, local potassium infusion, and ischemia.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1986, Volume: 6, Issue:5

    Topics: Adenosine; Animals; Brain; Brain Ischemia; Cerebrovascular Circulation; Dialysis; Extracellular Space; Hypoxanthine; Hypoxanthines; Hypoxia, Brain; Inosine; Male; Potassium; Rats; Rats, Inbred Strains

1986
Identification of hypoxanthine transport and xanthine oxidase activity in brain capillaries.
    Journal of neurochemistry, 1985, Volume: 44, Issue:2

    Topics: Adenine; Allopurinol; Animals; Biological Transport; Blood-Brain Barrier; Brain; Brain Ischemia; Capillaries; Cerebral Cortex; Hypoxanthine; Hypoxanthines; Kinetics; Rats; Uric Acid; Xanthine; Xanthine Oxidase; Xanthines

1985