hypoxanthine and Aging

hypoxanthine has been researched along with Aging in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19902 (10.53)18.7374
1990's7 (36.84)18.2507
2000's8 (42.11)29.6817
2010's2 (10.53)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Biasibetti-Brendler, H; de Andrade, RB; Pierozan, P; Prezzi, CA; Schmitz, F; Wannmacher, CMD; Wyse, ATS; Zanotto, BS1
Iseki, K; Kaneko, C; Kobayashi, M; Koizumi, T; Kuwayama, K; Ogura, J; Sasaki, S; Takaya, A; Takeno, R; Tsujimoto, T; Yabe, K; Yamaguchi, H1
Ishchenko, A; Krysanova, Z; Nevinsky, GA; Saparbaev, M; Sidorkina, O; Sinitsyna, O; Vasyunina, EA1
Garnham, B; Headrick, JP; Willems, L1
Aruoma, OI; Duracková, Z; Garaiová, I; Kalnovicová, T; Korytár, P; Muchová, J; Pueschel, S; Sustrová, M; Zitnanová, I1
Betzendahl, I; Cukurcam, S; Eichenlaub-Ritter, U; Hegele-Hartung, C; Lindenthal, B; Michel, G; Vogt, E1
Disteche, CM; Horn, PL; Martin, GM; Ogburn, CE; Turker, MS1
Oyasaeter, S; Reichelt, KL; Rognum, TO; Saugstad, OD; Stoltenberg, L; Storm, H1
Caldarera, CM; Finelli, C; Guarnieri, C; Muscari, C; Ventura, C1
Cline, CC; Coast, JR; Hu, Z; Lawler, JM1
Kakino, J; Naito, Y; Sato, R1
Delogu, MR; Desole, MS; Esposito, G; Miele, M; Migheli, R; Rocchitta, G; Serra, PA1
Delogu, MR; Desole, MS; Esposito, G; Fresu, L; Miele, M; Migheli, R; Rocchitta, G; Serra, PA1
Bohr, VA; Dianov, GL; Nyaga, SG; Souza-Pinto, N; Stevnsner, T; Thybo, T1
Bohr, VA; de Souza-Pinto, NC; Stevnsner, T1
Greenwood, R; Harkness, RA; McCreanor, GM1
Aranda, JV; Beharry, K; Farri, E; Laudignon, N1
Berne, RM; Coleman, SD; Headrick, JP; Matherne, GP1
Kim, HD; Metzler, MH; Moran, JB; Zeidler, RB1

Reviews

1 review(s) available for hypoxanthine and Aging

ArticleYear
Base excision repair in nuclear and mitochondrial DNA.
    Progress in nucleic acid research and molecular biology, 2001, Volume: 68

    Topics: Adenine; Aging; Animals; Base Sequence; Cell Line; Cell Nucleus; Cell-Free System; DNA; DNA Damage; DNA Glycosylases; DNA Polymerase beta; DNA Repair; DNA-Formamidopyrimidine Glycosylase; DNA, Mitochondrial; Guanine; Hypoxanthine; Lymphocytes; Mammals; Mice; Mitochondria; Molecular Sequence Data; N-Glycosyl Hydrolases; Oxidants; Oxidation-Reduction; Oxidative Stress; Point Mutation; Proliferating Cell Nuclear Antigen; Rats; Thymine

2001

Other Studies

18 other study(ies) available for hypoxanthine and Aging

ArticleYear
Hypoxanthine Induces Neuroenergetic Impairment and Cell Death in Striatum of Young Adult Wistar Rats.
    Molecular neurobiology, 2018, Volume: 55, Issue:5

    Topics: Aging; Animals; Cell Death; Corpus Striatum; Creatine Kinase; Electron Transport Complex IV; Energy Metabolism; Hypoxanthine; Male; Mitochondria; Pyruvate Kinase; Rats, Wistar; Succinate Dehydrogenase

2018
Reactive oxygen species derived from xanthine oxidase interrupt dimerization of breast cancer resistance protein, resulting in suppression of uric acid excretion to the intestinal lumen.
    Biochemical pharmacology, 2015, Sep-01, Volume: 97, Issue:1

    Topics: Aging; Allopurinol; Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Caco-2 Cells; Dimerization; Enzyme Induction; Enzyme Inhibitors; Gout Suppressants; Humans; Hyperuricemia; Hypoxanthine; Ileum; Inosine; Intestinal Elimination; Intestinal Mucosa; Male; Mitochondria; Neoplasm Proteins; Rats, Wistar; Reactive Oxygen Species; Uric Acid; Xanthine Oxidase

2015
Age-dependent increase of 8-oxoguanine-, hypoxanthine-, and uracil- DNA glycosylase activities in liver extracts from OXYS rats with inherited overgeneration of free radicals and Wistar rats.
    Medical science monitor : international medical journal of experimental and clinical research, 2003, Volume: 9, Issue:1

    Topics: Aging; Animals; Cell Nucleus; DNA Glycosylases; DNA-Formamidopyrimidine Glycosylase; Electrophoresis, Polyacrylamide Gel; Free Radicals; Glycoside Hydrolases; Guanine; Hypoxanthine; Liver; Male; Mitochondria; Mitochondria, Liver; N-Glycosyl Hydrolases; Rats; Rats, Wistar; Species Specificity; Time Factors; Uracil; Uracil-DNA Glycosidase; Urea

2003
Aging-related changes in myocardial purine metabolism and ischemic tolerance.
    Experimental gerontology, 2003, Volume: 38, Issue:10

    Topics: Adenosine; Aging; Animals; Female; Hypoxanthine; Inosine; Male; Mice; Mice, Inbred C57BL; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Organ Culture Techniques; Purines

2003
Uric acid and allantoin levels in Down syndrome: antioxidant and oxidative stress mechanisms?
    Clinica chimica acta; international journal of clinical chemistry, 2004, Volume: 341, Issue:1-2

    Topics: Adolescent; Aging; Allantoin; Antioxidants; Child; Chromatography, High Pressure Liquid; Down Syndrome; Female; Humans; Hypoxanthine; Indicators and Reagents; Male; Oxidative Stress; Reference Standards; Spectrophotometry, Ultraviolet; Uric Acid; Xanthine

2004
Influence of follicular fluid meiosis-activating sterol on aneuploidy rate and precocious chromatid segregation in aged mouse oocytes.
    Human reproduction (Oxford, England), 2007, Volume: 22, Issue:3

    Topics: Aging; Animals; Cell Cycle Proteins; Cellular Senescence; Cholestenes; Chromatids; Chromosome Segregation; Female; Hypoxanthine; Mad2 Proteins; Meiosis; Mice; Mice, Inbred CBA; Oocytes; Organic Chemicals; Polyploidy

2007
A cloning assay for 6-thioguanine resistance provides evidence against certain somatic mutational theories of aging.
    Journal of cellular physiology, 1984, Volume: 121, Issue:2

    Topics: Adenine; Adenine Phosphoribosyltransferase; Aging; Animals; Clone Cells; Drug Resistance; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Kidney; Male; Mice; Mice, Inbred Strains; Muscle Development; Muscles; Mutation; Thioguanine

1984
Beta-endorphin may be a mediator of apnea induced by the laryngeal chemoreflex in piglets.
    Pediatric research, 1995, Volume: 38, Issue:2

    Topics: Aging; Animals; Apnea; beta-Endorphin; Blood Glucose; Body Weight; Cisterna Magna; Female; Hematocrit; Hemoglobins; Hypoxanthine; Hypoxanthines; Injections; Larynx; Male; Pilot Projects; Reflex; Swine; Vitreous Body

1995
Incorporation of [14C]hypoxanthine into cardiac adenine nucleotides: effect of aging and post-ischemic reperfusion.
    Biochimica et biophysica acta, 1993, Jan-22, Volume: 1180, Issue:3

    Topics: Adenine Nucleotides; Aging; Animals; Hypoxanthine; Hypoxanthines; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Rats; Rats, Wistar; Uric Acid

1993
Effect of oxidant challenge on contractile function of the aging rat diaphragm.
    The American journal of physiology, 1997, Volume: 272, Issue:2 Pt 1

    Topics: Aging; Animals; Diaphragm; Electric Stimulation; Hypoxanthine; Muscle Contraction; Muscle Fatigue; Oxidative Stress; Rats; Rats, Inbred F344; Xanthine Oxidase

1997
Purine metabolism of uric acid urolithiasis induced in newborn piglets.
    The Journal of veterinary medical science, 1998, Volume: 60, Issue:2

    Topics: Aging; Allantoin; Animals; Animals, Newborn; Body Weight; Hypoxanthine; Purines; Swine; Swine Diseases; Uric Acid; Urinary Calculi; Xanthine

1998
Glutamate and catabolites of high-energy phosphates in the striatum and brainstem of young and aged rats subchronically exposed to manganese.
    Aging (Milan, Italy), 2000, Volume: 12, Issue:5

    Topics: Aging; Animals; Brain Stem; Corpus Striatum; Energy Metabolism; Glutamic Acid; Hypoxanthine; Male; Manganese; Osmolar Concentration; Phosphates; Rats; Rats, Wistar; Time Factors; Uric Acid; Xanthine

2000
Glutathione deficiency potentiates manganese-induced increases in compounds associated with high-energy phosphate degradation in discrete brain areas of young and aged rats.
    Aging (Milan, Italy), 2000, Volume: 12, Issue:6

    Topics: Aging; Animals; Antimetabolites; Ascorbic Acid; Brain; Buthionine Sulfoximine; Dehydroascorbic Acid; Drug Synergism; Energy Metabolism; Glutathione; Hypoxanthine; Inosine; Male; Manganese; Phosphates; Rats; Rats, Wistar; Tissue Distribution; Uric Acid; Xanthine

2000
Mitochondrial DNA repair of oxidative damage in mammalian cells.
    Gene, 2002, Mar-06, Volume: 286, Issue:1

    Topics: Adenine; Aging; Animals; Cell Nucleus; DNA Damage; DNA Glycosylases; DNA Ligases; DNA Repair; DNA-Binding Proteins; DNA-Formamidopyrimidine Glycosylase; DNA, Mitochondrial; Guanosine; Humans; Hypoxanthine; Mice; Mitochondria, Heart; Mitochondria, Liver; N-Glycosyl Hydrolases; Oxidative Stress; Rats; Reactive Oxygen Species; X-ray Repair Cross Complementing Protein 1

2002
The pathogenesis of the Lesch-Nyhan syndrome: ATP use is positively related to hypoxanthine supply to hypoxanthine guanine phosphoribosyltransferase.
    Journal of inherited metabolic disease, 1991, Volume: 14, Issue:2

    Topics: Adenosine Triphosphate; Adult; Aging; Body Mass Index; Creatinine; Exercise; Female; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Kinetics; Lesch-Nyhan Syndrome; Male; Middle Aged; Uric Acid; Xanthine; Xanthines

1991
Rapid effects of hypoxia on the cerebrospinal fluid levels of adenosine and related metabolites in newborn and one-month-old piglets.
    Biology of the neonate, 1991, Volume: 59, Issue:1

    Topics: Adenosine; Aging; Animals; Animals, Newborn; Blood Gas Analysis; Hypoxanthine; Hypoxanthines; Hypoxia; Inosine; Swine

1991
Interstitial transudate purines in normoxic and hypoxic immature and mature rabbit hearts.
    Pediatric research, 1990, Volume: 28, Issue:4

    Topics: Adenosine; Aging; Animals; Exudates and Transudates; Hemodynamics; Hypoxanthine; Hypoxanthines; Hypoxia; Inosine; Myocardium; Oxygen Consumption; Rabbits

1990
The liver is an organ site for the release of inosine metabolized by non-glycolytic pig red cells.
    Biochimica et biophysica acta, 1985, Mar-08, Volume: 838, Issue:3

    Topics: Adenosine Triphosphate; Aging; Animals; Energy Metabolism; Erythrocytes; Glycolysis; Hypoxanthine; Hypoxanthines; Inosine; Liver; Swine; Swine, Miniature; Uric Acid

1985