hypochlorous acid has been researched along with Disease Models, Animal in 54 studies
Timeframe | Studies, this research(%) | All Research% |
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pre-1990 | 1 (1.85) | 18.7374 |
1990's | 3 (5.56) | 18.2507 |
2000's | 7 (12.96) | 29.6817 |
2010's | 29 (53.70) | 24.3611 |
2020's | 14 (25.93) | 2.80 |
Authors | Studies |
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Ge, Y; Hu, L; Huang, J; Li, C; Li, D; Li, Y; Lin, X; Luo, J; Man, M; Yu, H; Zhang, J | 1 |
Li, T; Liu, B; Luo, XJ; Peng, J | 1 |
Kohan, L; Mohammadi, M; Mohammadi, S; Saeidi, M; Saghaeian Jazi, M | 1 |
Guo, Y; Liu, L; Wei, P; Yi, T; Zhou, X | 1 |
Chen, S; He, C; Hou, P; Li, Q; Li, Z; Liu, L; Liu, X | 1 |
Berger, S; Chadli, L; Chomel, A; Courtade-Gaïani, S; De Ceuninck, F; Desvaux, E; Elouej, S; Fould, B; Guerrier, T; Hubert, S; Jendoubi, M; Launay, D; Le Gall, M; Levasseur, F; Licznar, A; Neau, B; Nguyen, TQ; Nony, E; Ortega-Ferreira, C; Provost, N; Robin, G; Saint-Paul, J; Soret, P; Speca, S; Verdier, J | 1 |
Arthur, PG; Bakker, AJ; Lea, TA; Panizza, PM; Pinniger, GJ | 1 |
Colmegna, I; Fraser, R; Fujii, U; Joy, S; Martin, JG; Morozan, A; Watters, K | 1 |
Chen, W; Du, Q; Meng, M; Tan, J; Wang, K; Wang, N; Xie, B; Zhu, H | 1 |
Govindaraju, T; Samanta, S | 1 |
Chen, Y; Han, X; Ma, Y; Wang, X; Wang, Z | 1 |
Chen, Q; Gong, A; Han, Y; Han, Z; Li, L; Liu, W; Long, L; Wang, K; Yin, D; Yuan, F | 1 |
Deng, Y; Feng, G; Feng, S; Gong, S; Xia, Q | 1 |
Chang, YC; Chao, CY; Chen, YT; Hsu, YT; Lee, YJ; Lin, SL; Tsai, PS; Tsai, SY; Wei, YS; Wu, CH | 1 |
Chen, L; He, N; Huang, Y; Lv, C; Wang, X; Wang, Y; Yue, S | 1 |
Guilpain, P; Jorgensen, C; Lai-Kee-Him, J; Maria, ATJ; Maumus, M; Noël, D; Rozier, P; Toupet, K | 1 |
Bridle, KR; Crawford, DH; Jayachandran, A; Liang, X; Liu, X; Roberts, MS; Thomas, JA; Wang, H; Xu, ZP; Yuan, J; Zhang, R; Zhang, W | 1 |
Batteux, F; Cerles, O; Chéreau, C; Chouzenoux, S; Kavian, N; Morin, F; Nicco, C | 1 |
Bäumer, W; Ehling, S; Fukuyama, T; Ganchingco, JR; Linder, KE; Martel, BC | 1 |
Chen, J; Cheng, G; Huang, X; Li, X; Liu, Y; Liu, Z; Peng, H; Shi, R; Tang, Y; Xu, Q; You, B; Zhang, G; Zhang, K | 1 |
Bäumer, W; Ehling, S; Fukuyama, T; Wilzopolski, J | 1 |
Calixto, A; Chávez, FP | 1 |
Altavilla, D; Atteritano, M; Bagnato, G; Bitto, A; Cinquegrani, M; Irrera, N; Pizzino, G; Roberts, W; Saitta, A; Sangari, D; Squadrito, F | 1 |
Arnhold, J; Bäcker, I; Flemmig, J; Lange, F; Leichsenring, A; Schwarz, P | 1 |
Batteux, F; Chéreau, C; Chimini, G; Galland, F; Guilpain, P; Kavian, N; Lemaréchal, H; Marut, W; Naquet, P; Nicco, C; Servettaz, A; Weill, B | 1 |
Agrawalla, BK; Chang, YT; Park, SJ; Peng, J; Sivaraman, B; Wang, L; Xu, QH; Yuan, L; Zhu, H | 1 |
Batteux, F; Bei, Y; Chéreau, C; Dinh-Xuan, AT; Duong-Quy, S; Hua-Huy, T; Le-Dong, NN; Nicco, C; Rivière, S; Tiev, KP | 1 |
Batteux, F; Bony, C; Guilpain, P; Jorgensen, C; Le Quellec, A; Maria, AT; Noël, D; Petit, B; Pirot, N; Roger, P; Toupet, K; Vozenin, MC | 1 |
Altavilla, D; Bagnato, GF; Bagnato, GL; Bitto, A; Irrera, N; Minutoli, L; Pizzino, G; Roberts, WN; Russo, G; Saitta, A; Squadrito, F | 1 |
Batteux, F; Bei, Y; Chéreau, C; Dinh-Xuan, AT; Duong-Quy, S; Hua-Huy, T; Le-Dong, NN; Nicco, C; Tiev, KP | 1 |
Cheng, D; Maghzal, GJ; Stocker, R; Talib, J | 1 |
Böhm, M; Haub, J; Lorenz, N; Ook, KY; Raker, VK; Schmidt, T; Schuppan, D; Stegemann, A; Steinbrink, K | 1 |
Batteux, F; Cerles, O; Chéreau, C; Kavian, N; Morin, F; Nicco, C | 1 |
Chen, L; Cheng, G; Huang, X; Liu, Z; Peng, H; Shi, R; Xu, Q; Yang, T; Yang, W; Yu, Z; Zhang, G | 1 |
Dennis, JM; Kim, HB; McMahon, A; Szuchman-Sapir, A; Wang, XS; Witting, PK | 1 |
Kosumi, T; Kubota, A; Nose, K; Oyanagi, H; Yamauchi, K; Yonekura, T | 1 |
Batteux, F; Chéreau, C; Deveaux, V; Kavian, N; Lotersztajn, S; Nicco, C; Servettaz, A; Wang, A; Weill, B; Zimmer, A | 1 |
Bai, Y; Cao, Z; Cheng, G; Hu, C; Li, Y; Peng, J; Shi, R; Yang, T; Yuan, Q; Zhang, G | 1 |
Batteux, F; Kavian, N; Servettaz, A | 1 |
Ba, LA; Batteux, F; Chéreau, C; Doering, M; Jacob, C; Kavian, N; Marut, WK; Nicco, C; Servettaz, A; Weill, B | 1 |
Aratani, Y; Iwamoto, Y; Kubota, K; Kumamaru, H; Maeda, T; Nagano, T; Ohkawa, Y; Okada, S; Saiwai, H | 1 |
He, L; Hu, CP; Li, NS; Li, YJ; Liu, B; Luo, XJ; Ma, QL; Peng, J; Zhang, GG; Zhang, YS | 1 |
Gou, LT; Huang, WJ; Ma, C; Wang, YX; Yang, JL; Yao, YQ; Yi, C; Zhou, R; Zhou, Y | 1 |
Batteux, F; Chéreau, C; Dinh-Xuan, AT; Hua-Huy, T; Kavian, N; Marut, W; Nicco, C; Servettaz, A; Weill, B | 1 |
Nakamura, S; Okada, S; Saito, F; Umeda, Y | 1 |
Cheng, Y; Ji, R; Yang, J; Zhang, C | 1 |
Bucknall, RA; Jones, RA; Platt, J | 1 |
Guo, Y; Schneider, LA; Wangensteen, OD | 1 |
Boucher, JC; Deretic, V; Hibler, NS; Yu, H | 1 |
Hammerschmidt, S; Wahn, H | 1 |
Hayashi, K; Hosoe, H; Kaise, T; Ohmori, K | 1 |
Belaaouaj, A; Brennan, ML; Byun, J; Gaut, JP; Heinecke, JW; Henderson, JP; Hotchkiss, RS; Lusis, AJ; Richter, GM; Tran, HD; Yeh, GC | 1 |
Gröne, HJ; Malle, E; Sattler, W; Thiery, J; Wäg, G | 1 |
Büchler, N; Hammerschmidt, S; Wahn, H | 1 |
1 review(s) available for hypochlorous acid and Disease Models, Animal
Article | Year |
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New insights on chemically induced animal models of systemic sclerosis.
Topics: Animals; Autoimmunity; Bleomycin; Disease Models, Animal; Fibrosis; Humans; Hypochlorous Acid; Inflammation; Mice; Reactive Oxygen Species; Scleroderma, Systemic | 2011 |
53 other study(ies) available for hypochlorous acid and Disease Models, Animal
Article | Year |
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Deficiency of vitamin D receptor in keratinocytes augments dermal fibrosis and inflammation in a mouse model of HOCl-induced scleroderma.
Topics: Animals; Collagen; Dermis; Disease Models, Animal; Fibrosis; Hypochlorous Acid; Inflammation; Keratinocytes; Mice, Inbred C57BL; Mice, Knockout; Receptors, Calcitriol; Skin Diseases; Up-Regulation | 2022 |
VPO1/HOCl/ERK pathway mediates the right ventricular remodeling in rats with hypoxic pulmonary hypertension.
Topics: Animals; Cardiomegaly; Disease Models, Animal; Hypertension, Pulmonary; Hypochlorous Acid; Hypoxia; MAP Kinase Signaling System; Rats; Rats, Sprague-Dawley; Ventricular Remodeling | 2022 |
The antifibrotic effects of
Topics: Animals; Anti-Inflammatory Agents; Collagen; Dimethyl Sulfoxide; Disease Models, Animal; Female; Fibrosis; Flavanones; Hypochlorous Acid; Mice; Mice, Inbred BALB C; RNA, Messenger; Skin Diseases; Transforming Growth Factor beta | 2022 |
Hypochlorous acid triggered fluorescent probes for
Topics: Animals; Diagnostic Imaging; Disease Models, Animal; Fluorescent Dyes; Hypochlorous Acid; Mice; Psoriasis | 2022 |
HClO imaging in vivo and drug-damaged liver tissues by a large Stokes shift fluorescent probe.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Fluorescent Dyes; HeLa Cells; Humans; Hypochlorous Acid; Mice; Optical Imaging; Zebrafish | 2023 |
Antibody-mediated neutralization of galectin-3 as a strategy for the treatment of systemic sclerosis.
Topics: Animals; Antibodies, Monoclonal; Cross-Sectional Studies; Disease Models, Animal; Galectin 3; Hypochlorous Acid; Mice; Scleroderma, Systemic | 2023 |
Hypochlorous acid exposure impairs skeletal muscle function and Ca
Topics: Animals; Disease Models, Animal; Hypochlorous Acid; Inflammation; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Muscle, Skeletal; Muscular Dystrophy, Duchenne; Peroxidase | 2023 |
Superiority of systemic bleomycin to intradermal HOCl for the study of interstitial lung disease.
Topics: Animals; Bleomycin; Disease Models, Animal; Fibrosis; Hypochlorous Acid; Lung; Lung Diseases, Interstitial; Mice; NF-E2-Related Factor 2; Pulmonary Fibrosis; Scleroderma, Systemic; Skin | 2023 |
The Fibrosis and Immunological Features of Hypochlorous Acid Induced Mouse Model of Systemic Sclerosis.
Topics: Animals; Disease Models, Animal; Fibrosis; Hypochlorous Acid; Lung; Mice; Mice, Inbred BALB C; Oxidants; Scleroderma, Systemic; Skin | 2019 |
Unambiguous Detection of Elevated Levels of Hypochlorous Acid in Double Transgenic AD Mouse Brain.
Topics: Alzheimer Disease; Animals; Biomarkers; Blood-Brain Barrier; Brain Chemistry; Cell Line; Disease Models, Animal; Fluorescent Dyes; Hypochlorous Acid; Male; Mice; Mice, Transgenic; Microscopy, Confocal; Microscopy, Fluorescence; Neurons; Plaque, Amyloid; Thioamides | 2019 |
Enhancement of the Aggregation-Induced Emission by Hydrogen Bond for Visualizing Hypochlorous Acid in an Inflammation Model and a Hepatocellular Carcinoma Model.
Topics: Animals; Carcinoma, Hepatocellular; Disease Models, Animal; Female; Fluorescent Dyes; HeLa Cells; Humans; Hydrogen Bonding; Hypochlorous Acid; Inflammation; Lipopolysaccharides; Liver Neoplasms; Mice; Mice, Inbred Strains; Models, Molecular; Molecular Structure; Optical Imaging; RAW 264.7 Cells | 2020 |
Simultaneous Discrimination of Hypochlorite and Single Oxygen during Sepsis by a Dual-Functional Fluorescent Probe.
Topics: Animals; Disease Models, Animal; Fluorescent Dyes; Hypochlorous Acid; Optical Imaging; Oxygen; Rats; Rats, Sprague-Dawley; Sepsis | 2020 |
A novel reaction-based fluorescence probe for rapid imaging of HClO in live cells, animals, and injured liver tissues.
Topics: Animals; Disease Models, Animal; Fluorescent Dyes; HeLa Cells; Humans; Hypochlorous Acid; Liver; MCF-7 Cells; Mice; Mice, Inbred Strains; Molecular Structure; Optical Imaging; Particle Size; Surface Properties; Zebrafish | 2020 |
Hypochlorite-induced porcine model of peritoneal fibrosis through the activation of IL1β-CX3CL1-TGFβ1 signal axis.
Topics: Animals; Chemokine CX3CL1; Collagen Type I; Disease Models, Animal; Epithelial Cells; Humans; Hypochlorous Acid; Interleukin-1beta; Myofibroblasts; Peritoneal Dialysis; Peritoneal Fibrosis; Peritoneum; Signal Transduction; Swine; Transforming Growth Factor beta1 | 2020 |
Detection of hypochlorous acid fluctuation
Topics: A549 Cells; Acute Lung Injury; Animals; Disease Models, Animal; Fluorescent Dyes; Humans; Hypochlorous Acid; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Optical Imaging | 2020 |
Mesenchymal stromal cells-derived extracellular vesicles alleviate systemic sclerosis via miR-29a-3p.
Topics: Animals; Apoptosis; Disease Models, Animal; DNA Methylation; DNA Methyltransferase 3A; Extracellular Vesicles; Female; Gene Expression Regulation; Humans; Hypochlorous Acid; Mesenchymal Stem Cells; Mice; MicroRNAs; Receptor, Platelet-Derived Growth Factor beta; Scleroderma, Systemic | 2021 |
Two-photon dual imaging platform for in vivo monitoring cellular oxidative stress in liver injury.
Topics: Acetaminophen; Animals; Cell Line; Chemical and Drug Induced Liver Injury; Coordination Complexes; Disease Models, Animal; Fluorescent Dyes; Glutathione; Hydrogen Peroxide; Hypochlorous Acid; Liver; Male; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence, Multiphoton; Oxidative Stress; Reactive Oxygen Species; Ruthenium | 2017 |
Leflunomide prevents ROS-induced systemic fibrosis in mice.
Topics: Animals; Antirheumatic Agents; Autoantibodies; Bleomycin; Cells, Cultured; Disease Models, Animal; Female; Fibrosis; Humans; Hypochlorous Acid; Immunosuppression Therapy; Isoxazoles; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Leflunomide; Lymphocyte Activation; Macrophages; Mice; Mice, Inbred BALB C; Pulmonary Fibrosis; Reactive Oxygen Species; Signal Transduction; Skin; STAT6 Transcription Factor | 2017 |
Hypochlorous acid is antipruritic and anti-inflammatory in a mouse model of atopic dermatitis.
Topics: Animals; Anti-Inflammatory Agents; Antigens, Dermatophagoides; Antipruritics; Cytokines; Dermatitis, Atopic; Disease Models, Animal; Female; Hypochlorous Acid; Inflammation; Mice; Mice, Inbred BALB C | 2018 |
Vascular peroxidase 1 mediates hypoxia-induced pulmonary artery smooth muscle cell proliferation, apoptosis resistance and migration.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Cell Cycle Proteins; Cell Hypoxia; Cell Movement; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Hemeproteins; Hypertension, Pulmonary; Hypochlorous Acid; Hypoxia; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidase 4; NF-kappa B; Peroxidases; Pulmonary Artery; Rats, Sprague-Dawley; Signal Transduction; Vascular Remodeling | 2018 |
Comparison of topical tofacitinib and 0.1% hypochlorous acid in a murine atopic dermatitis model.
Topics: Administration, Topical; Animals; Cells, Cultured; Cytokines; Dermatitis, Atopic; Disease Models, Animal; Female; Ganglia, Spinal; Hypochlorous Acid; Immunoglobulin E; Mice; Neurons; Piperidines; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Skin | 2018 |
Use of C. elegans Diapause to Study Transgenerational Responses to Pathogen Infection.
Topics: Animals; Bacterial Infections; Caenorhabditis elegans; Diapause; Disease Models, Animal; Host-Pathogen Interactions; Hypochlorous Acid | 2019 |
Propylthiouracil prevents cutaneous and pulmonary fibrosis in the reactive oxygen species murine model of systemic sclerosis.
Topics: Actins; Animals; Antithyroid Agents; Blotting, Western; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Female; Fibrosis; Hypochlorous Acid; Hypothyroidism; Immunohistochemistry; Mice; Mice, Inbred BALB C; Muscle, Smooth; Oxidants; Propylthiouracil; Pulmonary Fibrosis; Random Allocation; ras Proteins; Scleroderma, Systemic; Skin; Thyrotropin; Thyroxine; Triiodothyronine; Vascular Endothelial Growth Factor A | 2013 |
Rapid and reliable determination of the halogenating peroxidase activity in blood samples.
Topics: Aniline Compounds; Animals; Asthma; Bromates; Cell Separation; Disease Models, Animal; Eosinophil Peroxidase; Eosinophils; Female; Flow Cytometry; Fluoresceins; Halogenation; Humans; Hypochlorous Acid; Mice; Mice, Inbred BALB C; Monocytes; Neutrophils; Peroxidase; Primary Cell Culture | 2014 |
Pantethine Prevents Murine Systemic Sclerosis Through the Inhibition of Microparticle Shedding.
Topics: Administration, Oral; Animals; ATP Binding Cassette Transporter 1; Bleomycin; Cell-Derived Microparticles; Cells, Cultured; Disease Models, Animal; Endothelial Cells; Female; Fibroblasts; Homeostasis; Hypochlorous Acid; In Vitro Techniques; Injections, Intradermal; Mice; Mice, Inbred BALB C; Mice, Knockout; Oxidative Stress; Pantetheine; Scleroderma, Systemic; Treatment Outcome | 2015 |
Development of targetable two-photon fluorescent probes to image hypochlorous Acid in mitochondria and lysosome in live cell and inflamed mouse model.
Topics: Animals; Cell Survival; Disease Models, Animal; Fluorescent Dyes; HeLa Cells; Humans; Hypochlorous Acid; Inflammation; Lipopolysaccharides; Lysosomes; Macrophages; Mice; Mitochondria; Molecular Structure; Photons; Spectrometry, Fluorescence | 2015 |
Increased exhaled nitric oxide precedes lung fibrosis in two murine models of systemic sclerosis.
Topics: Animals; Bleomycin; Breath Tests; Disease Models, Animal; Female; Hypochlorous Acid; Mice; Mice, Inbred C57BL; Nitric Oxide; Pulmonary Fibrosis; Scleroderma, Systemic; Skin | 2015 |
Antifibrotic, Antioxidant, and Immunomodulatory Effects of Mesenchymal Stem Cells in HOCl-Induced Systemic Sclerosis.
Topics: Actins; Animals; Autoantibodies; Collagen Type I; Collagen Type III; Disease Models, Animal; DNA Topoisomerases, Type I; Enzyme-Linked Immunosorbent Assay; Fibrosis; Hypochlorous Acid; Lung; Mesenchymal Stem Cell Transplantation; Mice; Oxidants; Oxidative Stress; Pulmonary Fibrosis; Reverse Transcriptase Polymerase Chain Reaction; Scleroderma, Diffuse; Skin; Transcriptome; Transforming Growth Factor beta1 | 2016 |
Simvastatin prevents vascular complications in the chronic reactive oxygen species murine model of systemic sclerosis.
Topics: Animals; Aorta; Carotid Intima-Media Thickness; Cell Differentiation; Collagen; Disease Models, Animal; Gene Expression Regulation; Humans; Hypochlorous Acid; Kidney; Mice; Myofibroblasts; Platelet Endothelial Cell Adhesion Molecule-1; Reactive Oxygen Species; Scleroderma, Systemic; Simvastatin; Vascular Endothelial Growth Factor Receptor-2 | 2016 |
RhoA/Rho-kinase activation promotes lung fibrosis in an animal model of systemic sclerosis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Animals; Disease Models, Animal; Female; Hypochlorous Acid; Lung; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Pneumonia; Pulmonary Fibrosis; rho-Associated Kinases; Scleroderma, Systemic; Skin; Smad2 Protein; Smad3 Protein; Tyrosine | 2016 |
Detailed protocol to assess in vivo and ex vivo myeloperoxidase activity in mouse models of vascular inflammation and disease using hydroethidine.
Topics: Animals; Biomarkers; Chromatography, Liquid; Disease Models, Animal; Halogenation; Humans; Hydrogen Peroxide; Hypochlorous Acid; Inflammation; Mice; Oxidation-Reduction; Peroxidase; Phenanthridines; Tandem Mass Spectrometry; Tyrosine; Vascular Diseases | 2016 |
Myeloid cell populations and fibrogenic parameters in bleomycin- and HOCl-induced fibrosis.
Topics: Animals; Bleomycin; Disease Models, Animal; Female; Fibrosis; Hypochlorous Acid; Mice, Inbred C57BL; Myeloid Cells; Scleroderma, Systemic; Skin | 2016 |
Niclosamide Prevents Systemic Sclerosis in a Reactive Oxygen Species-Induced Mouse Model.
Topics: Animals; Anthelmintics; Autoantibodies; B-Lymphocytes; Bleomycin; Cells, Cultured; Cytokines; Disease Models, Animal; DNA Topoisomerases, Type I; Female; Fibrosis; Humans; Hypochlorous Acid; Lung; Mice; Mice, Inbred BALB C; Niclosamide; Reactive Oxygen Species; Scleroderma, Systemic; Signal Transduction; Skin; T-Lymphocytes | 2016 |
Involvement of vascular peroxidase 1 in angiotensin II-induced hypertrophy of H9c2 cells.
Topics: Angiotensin II; Animals; Biphenyl Compounds; Cell Line; Disease Models, Animal; Endothelium, Vascular; Gene Knockdown Techniques; Hemeproteins; Hydrogen Peroxide; Hypertension; Hypertrophy; Hypochlorous Acid; Immunohistochemistry; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocytes, Cardiac; NADPH Oxidase 2; Onium Compounds; Oxidative Stress; Peroxidases; Phosphorylation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA Interference; RNA, Small Interfering; Signal Transduction; Up-Regulation | 2017 |
Neutrophils recruited to the myocardium after acute experimental myocardial infarct generate hypochlorous acid that oxidizes cardiac myoglobin.
Topics: Animals; Chromatography, Liquid; Disease Models, Animal; Heart; Heart Failure; Heart Ventricles; Hypochlorous Acid; Immunohistochemistry; Inflammation; Male; Myocardial Infarction; Myocardium; Myoglobin; Neutrophils; Oxygen; Rats; Rats, Wistar; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfoxides; Tandem Mass Spectrometry | 2016 |
Effect of electrolyzed strong acid water on peritoneal irrigation of experimental perforated peritonitis.
Topics: Animals; Disease Models, Animal; Electrolysis; Hydrogen-Ion Concentration; Hypochlorous Acid; Intestinal Perforation; Male; Peritoneal Lavage; Peritonitis; Rats; Rats, Wistar; Sodium Chloride; Statistics, Nonparametric; Survival Rate | 2009 |
Targeting the cannabinoid pathway limits the development of fibrosis and autoimmunity in a mouse model of systemic sclerosis.
Topics: Analgesics; Animals; Autoantibodies; Autoimmunity; Benzoxazines; Cannabinoids; Cell Proliferation; Cells, Cultured; Disease Models, Animal; DNA Topoisomerases, Type I; Female; Fibroblasts; Fibrosis; Humans; Hypochlorous Acid; Lung; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Morpholines; Naphthalenes; Oxidants; Random Allocation; Receptor, Cannabinoid, CB2; Scleroderma, Systemic; Signal Transduction; Skin | 2010 |
Involvement of vascular peroxidase 1 in angiotensin II-induced vascular smooth muscle cell proliferation.
Topics: Analysis of Variance; Angiotensin II; Animals; Aorta, Thoracic; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Enzyme Activation; Enzyme Inhibitors; Extracellular Matrix Proteins; Free Radical Scavengers; Hydrogen Peroxide; Hypertension; Hypochlorous Acid; Male; Mesenteric Arteries; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidases; Peroxidase; Peroxidasin; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA Interference; RNA, Messenger; Signal Transduction; Time Factors | 2011 |
The organotelluride catalyst (PHTE)₂NQ prevents HOCl-induced systemic sclerosis in mouse.
Topics: Actins; Animals; Autoantibodies; Cells, Cultured; Disease Models, Animal; DNA Topoisomerases, Type I; Female; Fibroblasts; Fibrosis; Glutathione; Hydrogen Peroxide; Hypochlorous Acid; In Vitro Techniques; Mice; Mice, Inbred BALB C; Naphthoquinones; Nitric Oxide; Organometallic Compounds; Reactive Oxygen Species; Scleroderma, Systemic; Skin; Tellurium | 2012 |
Myeloperoxidase exacerbates secondary injury by generating highly reactive oxygen species and mediating neutrophil recruitment in experimental spinal cord injury.
Topics: Animals; Apoptosis; Cytokines; Disease Models, Animal; Female; Flow Cytometry; Gene Expression Regulation; Hypochlorous Acid; Immunohistochemistry; In Situ Nick-End Labeling; Inflammation Mediators; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Neutrophil Infiltration; Oxidative Stress; Peroxidase; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Recovery of Function; Reverse Transcriptase Polymerase Chain Reaction; Spinal Cord; Spinal Cord Injuries; Time Factors | 2012 |
A novel pathway of NADPH oxidase/vascular peroxidase 1 in mediating oxidative injury following ischemia-reperfusion.
Topics: Animals; Apoptosis; Caspase 3; Cell Line; Creatine Kinase; Disease Models, Animal; Enzyme Inhibitors; Hemeproteins; Hydrogen Peroxide; Hypochlorous Acid; JNK Mitogen-Activated Protein Kinases; Male; Membrane Glycoproteins; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; NADPH Oxidase 2; NADPH Oxidase 4; NADPH Oxidases; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Peroxidases; Rats; Rats, Sprague-Dawley; RNA Interference; Signal Transduction; Transfection | 2012 |
HOCl oxidation-modified CT26 cell vaccine inhibits colon tumor growth in a mouse model.
Topics: Adenocarcinoma; Animals; Antibody-Dependent Cell Cytotoxicity; Apoptosis; Blotting, Western; Cancer Vaccines; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Cytotoxicity, Immunologic; Disease Models, Animal; Female; Flow Cytometry; Hypochlorous Acid; Immunoenzyme Techniques; Immunotherapy; Mice; Mice, Inbred BALB C; Oxidants; RNA, Messenger | 2012 |
Amelioration of systemic fibrosis in mice by angiotensin II receptor blockade.
Topics: Administration, Oral; Angiotensin II Type 1 Receptor Blockers; Animals; Biomarkers; Biphenyl Compounds; Breath Tests; Disease Models, Animal; Female; Fibrosis; Hypochlorous Acid; Injections, Intradermal; Irbesartan; Lung; Mice; Mice, Inbred BALB C; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidants; Pulmonary Fibrosis; Scleroderma, Systemic; Skin; Tetrazoles; Tyrosine | 2013 |
Development of a rabbit model of tear film instability and evaluation of viscosity of artificial tear preparations.
Topics: Animals; Cellulose; Chondroitin Sulfates; Disease Models, Animal; Dry Eye Syndromes; Hyaluronic Acid; Hypochlorous Acid; Hypromellose Derivatives; Methylcellulose; Ophthalmic Solutions; Rabbits; Tears; Viscosity | 2004 |
Novel model of inflammatory neointima formation reveals a potential role of myeloperoxidase in neointimal hyperplasia.
Topics: Animals; Apoptosis; Atherosclerosis; Carotid Arteries; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Hyperplasia; Hypochlorous Acid; Peroxidase; Rats; Rats, Sprague-Dawley; Time Factors; Tunica Intima; Tunica Media | 2006 |
Intraperitoneal antiseptics in experimental bacterial peritonitis.
Topics: Animals; Anti-Infective Agents, Local; Chlorhexidine; Disease Models, Animal; Escherichia coli Infections; Hypochlorous Acid; Injections, Intraperitoneal; Male; Mice; Noxythiolin; Peritonitis; Povidone-Iodine; Taurine; Thiadiazines; Time Factors | 1984 |
HOCl effects on tracheal epithelium: conductance and permeability measurements.
Topics: Aging; Animals; Ascorbic Acid; Cell Membrane Permeability; Disease Models, Animal; Epithelium; Hypochlorous Acid; Ion Transport; Male; Membrane Potentials; Patch-Clamp Techniques; Rabbits; Respiratory Tract Diseases; Trachea | 1995 |
Virulence properties of Pseudomonas aeruginosa lacking the extreme-stress sigma factor AlgU (sigmaE).
Topics: Animals; Bacterial Proteins; Blood Bactericidal Activity; Cystic Fibrosis; Disease Models, Animal; Humans; Hypochlorous Acid; In Vitro Techniques; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mutation; Opportunistic Infections; Pseudomonas aeruginosa; Pseudomonas Infections; Sepsis; Sigma Factor; Virulence | 1996 |
Comparable effects of HOCl and of FMLP-stimulated PMN on the circulation in an isolated lung model.
Topics: Animals; Disease Models, Animal; Extravascular Lung Water; Hypochlorous Acid; In Vitro Techniques; Infusions, Intravenous; Microcirculation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Oxidative Stress; Pulmonary Circulation; Pulmonary Wedge Pressure; Rabbits; Reproducibility of Results; Respiratory Distress Syndrome; Time Factors | 1997 |
Protective effect of erdosteine against hypochlorous acid-induced acute lung injury and lipopolysaccharide-induced neutrophilic lung inflammation in mice.
Topics: Administration, Oral; Animals; Bronchitis; Bronchoalveolar Lavage Fluid; Chronic Disease; Disease Models, Animal; Expectorants; Hypochlorous Acid; Inflammation; Lipopolysaccharides; Lung; Male; Mice; Mice, Inbred BALB C; Reactive Oxygen Species; Thioglycolates; Thiophenes; Tumor Necrosis Factor-alpha | 2000 |
Neutrophils employ the myeloperoxidase system to generate antimicrobial brominating and chlorinating oxidants during sepsis.
Topics: Animals; Bromine; Chlorine; Disease Models, Animal; HL-60 Cells; Humans; Hypochlorous Acid; Ions; Klebsiella Infections; Klebsiella pneumoniae; Mice; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Oxidants; Peroxidase; Sepsis; Tyrosine | 2001 |
Hypochlorite-modified (lipo)proteins are present in rabbit lesions in response to dietary cholesterol.
Topics: Animals; Arteriosclerosis; Cholesterol, Dietary; Diet, Atherogenic; Disease Models, Animal; Humans; Hyperlipidemias; Hypochlorous Acid; Inflammation; Lipoproteins; Monocytes; Oxidants; Peroxidase; Proteins; Rabbits | 2001 |
Tissue lipid peroxidation and reduced glutathione depletion in hypochlorite-induced lung injury.
Topics: Animals; Capillary Permeability; Disease Models, Animal; Glutathione; Hypochlorous Acid; In Vitro Techniques; Lipid Peroxidation; Lung; Neutrophils; Pulmonary Circulation; Pulmonary Edema; Rabbits; Respiratory Distress Syndrome | 2002 |