Page last updated: 2024-08-22

hypochlorous acid and Disease Models, Animal

hypochlorous acid has been researched along with Disease Models, Animal in 54 studies

Research

Studies (54)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.85)18.7374
1990's3 (5.56)18.2507
2000's7 (12.96)29.6817
2010's29 (53.70)24.3611
2020's14 (25.93)2.80

Authors

AuthorsStudies
Ge, Y; Hu, L; Huang, J; Li, C; Li, D; Li, Y; Lin, X; Luo, J; Man, M; Yu, H; Zhang, J1
Li, T; Liu, B; Luo, XJ; Peng, J1
Kohan, L; Mohammadi, M; Mohammadi, S; Saeidi, M; Saghaeian Jazi, M1
Guo, Y; Liu, L; Wei, P; Yi, T; Zhou, X1
Chen, S; He, C; Hou, P; Li, Q; Li, Z; Liu, L; Liu, X1
Berger, S; Chadli, L; Chomel, A; Courtade-Gaïani, S; De Ceuninck, F; Desvaux, E; Elouej, S; Fould, B; Guerrier, T; Hubert, S; Jendoubi, M; Launay, D; Le Gall, M; Levasseur, F; Licznar, A; Neau, B; Nguyen, TQ; Nony, E; Ortega-Ferreira, C; Provost, N; Robin, G; Saint-Paul, J; Soret, P; Speca, S; Verdier, J1
Arthur, PG; Bakker, AJ; Lea, TA; Panizza, PM; Pinniger, GJ1
Colmegna, I; Fraser, R; Fujii, U; Joy, S; Martin, JG; Morozan, A; Watters, K1
Chen, W; Du, Q; Meng, M; Tan, J; Wang, K; Wang, N; Xie, B; Zhu, H1
Govindaraju, T; Samanta, S1
Chen, Y; Han, X; Ma, Y; Wang, X; Wang, Z1
Chen, Q; Gong, A; Han, Y; Han, Z; Li, L; Liu, W; Long, L; Wang, K; Yin, D; Yuan, F1
Deng, Y; Feng, G; Feng, S; Gong, S; Xia, Q1
Chang, YC; Chao, CY; Chen, YT; Hsu, YT; Lee, YJ; Lin, SL; Tsai, PS; Tsai, SY; Wei, YS; Wu, CH1
Chen, L; He, N; Huang, Y; Lv, C; Wang, X; Wang, Y; Yue, S1
Guilpain, P; Jorgensen, C; Lai-Kee-Him, J; Maria, ATJ; Maumus, M; Noël, D; Rozier, P; Toupet, K1
Bridle, KR; Crawford, DH; Jayachandran, A; Liang, X; Liu, X; Roberts, MS; Thomas, JA; Wang, H; Xu, ZP; Yuan, J; Zhang, R; Zhang, W1
Batteux, F; Cerles, O; Chéreau, C; Chouzenoux, S; Kavian, N; Morin, F; Nicco, C1
Bäumer, W; Ehling, S; Fukuyama, T; Ganchingco, JR; Linder, KE; Martel, BC1
Chen, J; Cheng, G; Huang, X; Li, X; Liu, Y; Liu, Z; Peng, H; Shi, R; Tang, Y; Xu, Q; You, B; Zhang, G; Zhang, K1
Bäumer, W; Ehling, S; Fukuyama, T; Wilzopolski, J1
Calixto, A; Chávez, FP1
Altavilla, D; Atteritano, M; Bagnato, G; Bitto, A; Cinquegrani, M; Irrera, N; Pizzino, G; Roberts, W; Saitta, A; Sangari, D; Squadrito, F1
Arnhold, J; Bäcker, I; Flemmig, J; Lange, F; Leichsenring, A; Schwarz, P1
Batteux, F; Chéreau, C; Chimini, G; Galland, F; Guilpain, P; Kavian, N; Lemaréchal, H; Marut, W; Naquet, P; Nicco, C; Servettaz, A; Weill, B1
Agrawalla, BK; Chang, YT; Park, SJ; Peng, J; Sivaraman, B; Wang, L; Xu, QH; Yuan, L; Zhu, H1
Batteux, F; Bei, Y; Chéreau, C; Dinh-Xuan, AT; Duong-Quy, S; Hua-Huy, T; Le-Dong, NN; Nicco, C; Rivière, S; Tiev, KP1
Batteux, F; Bony, C; Guilpain, P; Jorgensen, C; Le Quellec, A; Maria, AT; Noël, D; Petit, B; Pirot, N; Roger, P; Toupet, K; Vozenin, MC1
Altavilla, D; Bagnato, GF; Bagnato, GL; Bitto, A; Irrera, N; Minutoli, L; Pizzino, G; Roberts, WN; Russo, G; Saitta, A; Squadrito, F1
Batteux, F; Bei, Y; Chéreau, C; Dinh-Xuan, AT; Duong-Quy, S; Hua-Huy, T; Le-Dong, NN; Nicco, C; Tiev, KP1
Cheng, D; Maghzal, GJ; Stocker, R; Talib, J1
Böhm, M; Haub, J; Lorenz, N; Ook, KY; Raker, VK; Schmidt, T; Schuppan, D; Stegemann, A; Steinbrink, K1
Batteux, F; Cerles, O; Chéreau, C; Kavian, N; Morin, F; Nicco, C1
Chen, L; Cheng, G; Huang, X; Liu, Z; Peng, H; Shi, R; Xu, Q; Yang, T; Yang, W; Yu, Z; Zhang, G1
Dennis, JM; Kim, HB; McMahon, A; Szuchman-Sapir, A; Wang, XS; Witting, PK1
Kosumi, T; Kubota, A; Nose, K; Oyanagi, H; Yamauchi, K; Yonekura, T1
Batteux, F; Chéreau, C; Deveaux, V; Kavian, N; Lotersztajn, S; Nicco, C; Servettaz, A; Wang, A; Weill, B; Zimmer, A1
Bai, Y; Cao, Z; Cheng, G; Hu, C; Li, Y; Peng, J; Shi, R; Yang, T; Yuan, Q; Zhang, G1
Batteux, F; Kavian, N; Servettaz, A1
Ba, LA; Batteux, F; Chéreau, C; Doering, M; Jacob, C; Kavian, N; Marut, WK; Nicco, C; Servettaz, A; Weill, B1
Aratani, Y; Iwamoto, Y; Kubota, K; Kumamaru, H; Maeda, T; Nagano, T; Ohkawa, Y; Okada, S; Saiwai, H1
He, L; Hu, CP; Li, NS; Li, YJ; Liu, B; Luo, XJ; Ma, QL; Peng, J; Zhang, GG; Zhang, YS1
Gou, LT; Huang, WJ; Ma, C; Wang, YX; Yang, JL; Yao, YQ; Yi, C; Zhou, R; Zhou, Y1
Batteux, F; Chéreau, C; Dinh-Xuan, AT; Hua-Huy, T; Kavian, N; Marut, W; Nicco, C; Servettaz, A; Weill, B1
Nakamura, S; Okada, S; Saito, F; Umeda, Y1
Cheng, Y; Ji, R; Yang, J; Zhang, C1
Bucknall, RA; Jones, RA; Platt, J1
Guo, Y; Schneider, LA; Wangensteen, OD1
Boucher, JC; Deretic, V; Hibler, NS; Yu, H1
Hammerschmidt, S; Wahn, H1
Hayashi, K; Hosoe, H; Kaise, T; Ohmori, K1
Belaaouaj, A; Brennan, ML; Byun, J; Gaut, JP; Heinecke, JW; Henderson, JP; Hotchkiss, RS; Lusis, AJ; Richter, GM; Tran, HD; Yeh, GC1
Gröne, HJ; Malle, E; Sattler, W; Thiery, J; Wäg, G1
Büchler, N; Hammerschmidt, S; Wahn, H1

Reviews

1 review(s) available for hypochlorous acid and Disease Models, Animal

ArticleYear
New insights on chemically induced animal models of systemic sclerosis.
    Current opinion in rheumatology, 2011, Volume: 23, Issue:6

    Topics: Animals; Autoimmunity; Bleomycin; Disease Models, Animal; Fibrosis; Humans; Hypochlorous Acid; Inflammation; Mice; Reactive Oxygen Species; Scleroderma, Systemic

2011

Other Studies

53 other study(ies) available for hypochlorous acid and Disease Models, Animal

ArticleYear
Deficiency of vitamin D receptor in keratinocytes augments dermal fibrosis and inflammation in a mouse model of HOCl-induced scleroderma.
    Biochemical and biophysical research communications, 2022, 02-05, Volume: 591

    Topics: Animals; Collagen; Dermis; Disease Models, Animal; Fibrosis; Hypochlorous Acid; Inflammation; Keratinocytes; Mice, Inbred C57BL; Mice, Knockout; Receptors, Calcitriol; Skin Diseases; Up-Regulation

2022
VPO1/HOCl/ERK pathway mediates the right ventricular remodeling in rats with hypoxic pulmonary hypertension.
    Archives of biochemistry and biophysics, 2022, 07-15, Volume: 723

    Topics: Animals; Cardiomegaly; Disease Models, Animal; Hypertension, Pulmonary; Hypochlorous Acid; Hypoxia; MAP Kinase Signaling System; Rats; Rats, Sprague-Dawley; Ventricular Remodeling

2022
The antifibrotic effects of
    Immunopharmacology and immunotoxicology, 2022, Volume: 44, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Collagen; Dimethyl Sulfoxide; Disease Models, Animal; Female; Fibrosis; Flavanones; Hypochlorous Acid; Mice; Mice, Inbred BALB C; RNA, Messenger; Skin Diseases; Transforming Growth Factor beta

2022
Hypochlorous acid triggered fluorescent probes for
    Journal of materials chemistry. B, 2022, 07-13, Volume: 10, Issue:27

    Topics: Animals; Diagnostic Imaging; Disease Models, Animal; Fluorescent Dyes; Hypochlorous Acid; Mice; Psoriasis

2022
HClO imaging in vivo and drug-damaged liver tissues by a large Stokes shift fluorescent probe.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2023, Dec-05, Volume: 302

    Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Fluorescent Dyes; HeLa Cells; Humans; Hypochlorous Acid; Mice; Optical Imaging; Zebrafish

2023
Antibody-mediated neutralization of galectin-3 as a strategy for the treatment of systemic sclerosis.
    Nature communications, 2023, 08-31, Volume: 14, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Cross-Sectional Studies; Disease Models, Animal; Galectin 3; Hypochlorous Acid; Mice; Scleroderma, Systemic

2023
Hypochlorous acid exposure impairs skeletal muscle function and Ca
    The Journal of physiology, 2023, Volume: 601, Issue:23

    Topics: Animals; Disease Models, Animal; Hypochlorous Acid; Inflammation; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Muscle, Skeletal; Muscular Dystrophy, Duchenne; Peroxidase

2023
Superiority of systemic bleomycin to intradermal HOCl for the study of interstitial lung disease.
    Scientific reports, 2023, Nov-23, Volume: 13, Issue:1

    Topics: Animals; Bleomycin; Disease Models, Animal; Fibrosis; Hypochlorous Acid; Lung; Lung Diseases, Interstitial; Mice; NF-E2-Related Factor 2; Pulmonary Fibrosis; Scleroderma, Systemic; Skin

2023
The Fibrosis and Immunological Features of Hypochlorous Acid Induced Mouse Model of Systemic Sclerosis.
    Frontiers in immunology, 2019, Volume: 10

    Topics: Animals; Disease Models, Animal; Fibrosis; Hypochlorous Acid; Lung; Mice; Mice, Inbred BALB C; Oxidants; Scleroderma, Systemic; Skin

2019
Unambiguous Detection of Elevated Levels of Hypochlorous Acid in Double Transgenic AD Mouse Brain.
    ACS chemical neuroscience, 2019, 12-18, Volume: 10, Issue:12

    Topics: Alzheimer Disease; Animals; Biomarkers; Blood-Brain Barrier; Brain Chemistry; Cell Line; Disease Models, Animal; Fluorescent Dyes; Hypochlorous Acid; Male; Mice; Mice, Transgenic; Microscopy, Confocal; Microscopy, Fluorescence; Neurons; Plaque, Amyloid; Thioamides

2019
Enhancement of the Aggregation-Induced Emission by Hydrogen Bond for Visualizing Hypochlorous Acid in an Inflammation Model and a Hepatocellular Carcinoma Model.
    Analytical chemistry, 2020, 02-04, Volume: 92, Issue:3

    Topics: Animals; Carcinoma, Hepatocellular; Disease Models, Animal; Female; Fluorescent Dyes; HeLa Cells; Humans; Hydrogen Bonding; Hypochlorous Acid; Inflammation; Lipopolysaccharides; Liver Neoplasms; Mice; Mice, Inbred Strains; Models, Molecular; Molecular Structure; Optical Imaging; RAW 264.7 Cells

2020
Simultaneous Discrimination of Hypochlorite and Single Oxygen during Sepsis by a Dual-Functional Fluorescent Probe.
    Analytical chemistry, 2020, 04-21, Volume: 92, Issue:8

    Topics: Animals; Disease Models, Animal; Fluorescent Dyes; Hypochlorous Acid; Optical Imaging; Oxygen; Rats; Rats, Sprague-Dawley; Sepsis

2020
A novel reaction-based fluorescence probe for rapid imaging of HClO in live cells, animals, and injured liver tissues.
    Talanta, 2020, Aug-01, Volume: 215

    Topics: Animals; Disease Models, Animal; Fluorescent Dyes; HeLa Cells; Humans; Hypochlorous Acid; Liver; MCF-7 Cells; Mice; Mice, Inbred Strains; Molecular Structure; Optical Imaging; Particle Size; Surface Properties; Zebrafish

2020
Hypochlorite-induced porcine model of peritoneal fibrosis through the activation of IL1β-CX3CL1-TGFβ1 signal axis.
    Scientific reports, 2020, 07-13, Volume: 10, Issue:1

    Topics: Animals; Chemokine CX3CL1; Collagen Type I; Disease Models, Animal; Epithelial Cells; Humans; Hypochlorous Acid; Interleukin-1beta; Myofibroblasts; Peritoneal Dialysis; Peritoneal Fibrosis; Peritoneum; Signal Transduction; Swine; Transforming Growth Factor beta1

2020
Detection of hypochlorous acid fluctuation
    Journal of materials chemistry. B, 2020, 11-11, Volume: 8, Issue:43

    Topics: A549 Cells; Acute Lung Injury; Animals; Disease Models, Animal; Fluorescent Dyes; Humans; Hypochlorous Acid; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Optical Imaging

2020
Mesenchymal stromal cells-derived extracellular vesicles alleviate systemic sclerosis via miR-29a-3p.
    Journal of autoimmunity, 2021, Volume: 121

    Topics: Animals; Apoptosis; Disease Models, Animal; DNA Methylation; DNA Methyltransferase 3A; Extracellular Vesicles; Female; Gene Expression Regulation; Humans; Hypochlorous Acid; Mesenchymal Stem Cells; Mice; MicroRNAs; Receptor, Platelet-Derived Growth Factor beta; Scleroderma, Systemic

2021
Two-photon dual imaging platform for in vivo monitoring cellular oxidative stress in liver injury.
    Scientific reports, 2017, 03-28, Volume: 7

    Topics: Acetaminophen; Animals; Cell Line; Chemical and Drug Induced Liver Injury; Coordination Complexes; Disease Models, Animal; Fluorescent Dyes; Glutathione; Hydrogen Peroxide; Hypochlorous Acid; Liver; Male; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence, Multiphoton; Oxidative Stress; Reactive Oxygen Species; Ruthenium

2017
Leflunomide prevents ROS-induced systemic fibrosis in mice.
    Free radical biology & medicine, 2017, Volume: 108

    Topics: Animals; Antirheumatic Agents; Autoantibodies; Bleomycin; Cells, Cultured; Disease Models, Animal; Female; Fibrosis; Humans; Hypochlorous Acid; Immunosuppression Therapy; Isoxazoles; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Leflunomide; Lymphocyte Activation; Macrophages; Mice; Mice, Inbred BALB C; Pulmonary Fibrosis; Reactive Oxygen Species; Signal Transduction; Skin; STAT6 Transcription Factor

2017
Hypochlorous acid is antipruritic and anti-inflammatory in a mouse model of atopic dermatitis.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2018, Volume: 48, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Antigens, Dermatophagoides; Antipruritics; Cytokines; Dermatitis, Atopic; Disease Models, Animal; Female; Hypochlorous Acid; Inflammation; Mice; Mice, Inbred BALB C

2018
Vascular peroxidase 1 mediates hypoxia-induced pulmonary artery smooth muscle cell proliferation, apoptosis resistance and migration.
    Cardiovascular research, 2018, 01-01, Volume: 114, Issue:1

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Cell Cycle Proteins; Cell Hypoxia; Cell Movement; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Hemeproteins; Hypertension, Pulmonary; Hypochlorous Acid; Hypoxia; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidase 4; NF-kappa B; Peroxidases; Pulmonary Artery; Rats, Sprague-Dawley; Signal Transduction; Vascular Remodeling

2018
Comparison of topical tofacitinib and 0.1% hypochlorous acid in a murine atopic dermatitis model.
    BMC pharmacology & toxicology, 2018, 07-03, Volume: 19, Issue:1

    Topics: Administration, Topical; Animals; Cells, Cultured; Cytokines; Dermatitis, Atopic; Disease Models, Animal; Female; Ganglia, Spinal; Hypochlorous Acid; Immunoglobulin E; Mice; Neurons; Piperidines; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Skin

2018
Use of C. elegans Diapause to Study Transgenerational Responses to Pathogen Infection.
    Methods in molecular biology (Clifton, N.J.), 2019, Volume: 1918

    Topics: Animals; Bacterial Infections; Caenorhabditis elegans; Diapause; Disease Models, Animal; Host-Pathogen Interactions; Hypochlorous Acid

2019
Propylthiouracil prevents cutaneous and pulmonary fibrosis in the reactive oxygen species murine model of systemic sclerosis.
    Arthritis research & therapy, 2013, Sep-16, Volume: 15, Issue:5

    Topics: Actins; Animals; Antithyroid Agents; Blotting, Western; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Female; Fibrosis; Hypochlorous Acid; Hypothyroidism; Immunohistochemistry; Mice; Mice, Inbred BALB C; Muscle, Smooth; Oxidants; Propylthiouracil; Pulmonary Fibrosis; Random Allocation; ras Proteins; Scleroderma, Systemic; Skin; Thyrotropin; Thyroxine; Triiodothyronine; Vascular Endothelial Growth Factor A

2013
Rapid and reliable determination of the halogenating peroxidase activity in blood samples.
    Journal of immunological methods, 2014, Dec-15, Volume: 415

    Topics: Aniline Compounds; Animals; Asthma; Bromates; Cell Separation; Disease Models, Animal; Eosinophil Peroxidase; Eosinophils; Female; Flow Cytometry; Fluoresceins; Halogenation; Humans; Hypochlorous Acid; Mice; Mice, Inbred BALB C; Monocytes; Neutrophils; Peroxidase; Primary Cell Culture

2014
Pantethine Prevents Murine Systemic Sclerosis Through the Inhibition of Microparticle Shedding.
    Arthritis & rheumatology (Hoboken, N.J.), 2015, Volume: 67, Issue:7

    Topics: Administration, Oral; Animals; ATP Binding Cassette Transporter 1; Bleomycin; Cell-Derived Microparticles; Cells, Cultured; Disease Models, Animal; Endothelial Cells; Female; Fibroblasts; Homeostasis; Hypochlorous Acid; In Vitro Techniques; Injections, Intradermal; Mice; Mice, Inbred BALB C; Mice, Knockout; Oxidative Stress; Pantetheine; Scleroderma, Systemic; Treatment Outcome

2015
Development of targetable two-photon fluorescent probes to image hypochlorous Acid in mitochondria and lysosome in live cell and inflamed mouse model.
    Journal of the American Chemical Society, 2015, May-13, Volume: 137, Issue:18

    Topics: Animals; Cell Survival; Disease Models, Animal; Fluorescent Dyes; HeLa Cells; Humans; Hypochlorous Acid; Inflammation; Lipopolysaccharides; Lysosomes; Macrophages; Mice; Mitochondria; Molecular Structure; Photons; Spectrometry, Fluorescence

2015
Increased exhaled nitric oxide precedes lung fibrosis in two murine models of systemic sclerosis.
    Journal of breath research, 2015, Jun-16, Volume: 9, Issue:3

    Topics: Animals; Bleomycin; Breath Tests; Disease Models, Animal; Female; Hypochlorous Acid; Mice; Mice, Inbred C57BL; Nitric Oxide; Pulmonary Fibrosis; Scleroderma, Systemic; Skin

2015
Antifibrotic, Antioxidant, and Immunomodulatory Effects of Mesenchymal Stem Cells in HOCl-Induced Systemic Sclerosis.
    Arthritis & rheumatology (Hoboken, N.J.), 2016, Volume: 68, Issue:4

    Topics: Actins; Animals; Autoantibodies; Collagen Type I; Collagen Type III; Disease Models, Animal; DNA Topoisomerases, Type I; Enzyme-Linked Immunosorbent Assay; Fibrosis; Hypochlorous Acid; Lung; Mesenchymal Stem Cell Transplantation; Mice; Oxidants; Oxidative Stress; Pulmonary Fibrosis; Reverse Transcriptase Polymerase Chain Reaction; Scleroderma, Diffuse; Skin; Transcriptome; Transforming Growth Factor beta1

2016
Simvastatin prevents vascular complications in the chronic reactive oxygen species murine model of systemic sclerosis.
    Free radical research, 2016, Volume: 50, Issue:5

    Topics: Animals; Aorta; Carotid Intima-Media Thickness; Cell Differentiation; Collagen; Disease Models, Animal; Gene Expression Regulation; Humans; Hypochlorous Acid; Kidney; Mice; Myofibroblasts; Platelet Endothelial Cell Adhesion Molecule-1; Reactive Oxygen Species; Scleroderma, Systemic; Simvastatin; Vascular Endothelial Growth Factor Receptor-2

2016
RhoA/Rho-kinase activation promotes lung fibrosis in an animal model of systemic sclerosis.
    Experimental lung research, 2016, Volume: 42, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Animals; Disease Models, Animal; Female; Hypochlorous Acid; Lung; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Pneumonia; Pulmonary Fibrosis; rho-Associated Kinases; Scleroderma, Systemic; Skin; Smad2 Protein; Smad3 Protein; Tyrosine

2016
Detailed protocol to assess in vivo and ex vivo myeloperoxidase activity in mouse models of vascular inflammation and disease using hydroethidine.
    Free radical biology & medicine, 2016, Volume: 97

    Topics: Animals; Biomarkers; Chromatography, Liquid; Disease Models, Animal; Halogenation; Humans; Hydrogen Peroxide; Hypochlorous Acid; Inflammation; Mice; Oxidation-Reduction; Peroxidase; Phenanthridines; Tandem Mass Spectrometry; Tyrosine; Vascular Diseases

2016
Myeloid cell populations and fibrogenic parameters in bleomycin- and HOCl-induced fibrosis.
    Experimental dermatology, 2016, Volume: 25, Issue:11

    Topics: Animals; Bleomycin; Disease Models, Animal; Female; Fibrosis; Hypochlorous Acid; Mice, Inbred C57BL; Myeloid Cells; Scleroderma, Systemic; Skin

2016
Niclosamide Prevents Systemic Sclerosis in a Reactive Oxygen Species-Induced Mouse Model.
    Journal of immunology (Baltimore, Md. : 1950), 2016, 10-15, Volume: 197, Issue:8

    Topics: Animals; Anthelmintics; Autoantibodies; B-Lymphocytes; Bleomycin; Cells, Cultured; Cytokines; Disease Models, Animal; DNA Topoisomerases, Type I; Female; Fibrosis; Humans; Hypochlorous Acid; Lung; Mice; Mice, Inbred BALB C; Niclosamide; Reactive Oxygen Species; Scleroderma, Systemic; Signal Transduction; Skin; T-Lymphocytes

2016
Involvement of vascular peroxidase 1 in angiotensin II-induced hypertrophy of H9c2 cells.
    Journal of the American Society of Hypertension : JASH, 2017, Volume: 11, Issue:8

    Topics: Angiotensin II; Animals; Biphenyl Compounds; Cell Line; Disease Models, Animal; Endothelium, Vascular; Gene Knockdown Techniques; Hemeproteins; Hydrogen Peroxide; Hypertension; Hypertrophy; Hypochlorous Acid; Immunohistochemistry; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocytes, Cardiac; NADPH Oxidase 2; Onium Compounds; Oxidative Stress; Peroxidases; Phosphorylation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA Interference; RNA, Small Interfering; Signal Transduction; Up-Regulation

2017
Neutrophils recruited to the myocardium after acute experimental myocardial infarct generate hypochlorous acid that oxidizes cardiac myoglobin.
    Archives of biochemistry and biophysics, 2016, Dec-15, Volume: 612

    Topics: Animals; Chromatography, Liquid; Disease Models, Animal; Heart; Heart Failure; Heart Ventricles; Hypochlorous Acid; Immunohistochemistry; Inflammation; Male; Myocardial Infarction; Myocardium; Myoglobin; Neutrophils; Oxygen; Rats; Rats, Wistar; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfoxides; Tandem Mass Spectrometry

2016
Effect of electrolyzed strong acid water on peritoneal irrigation of experimental perforated peritonitis.
    Surgery today, 2009, Volume: 39, Issue:6

    Topics: Animals; Disease Models, Animal; Electrolysis; Hydrogen-Ion Concentration; Hypochlorous Acid; Intestinal Perforation; Male; Peritoneal Lavage; Peritonitis; Rats; Rats, Wistar; Sodium Chloride; Statistics, Nonparametric; Survival Rate

2009
Targeting the cannabinoid pathway limits the development of fibrosis and autoimmunity in a mouse model of systemic sclerosis.
    The American journal of pathology, 2010, Volume: 177, Issue:1

    Topics: Analgesics; Animals; Autoantibodies; Autoimmunity; Benzoxazines; Cannabinoids; Cell Proliferation; Cells, Cultured; Disease Models, Animal; DNA Topoisomerases, Type I; Female; Fibroblasts; Fibrosis; Humans; Hypochlorous Acid; Lung; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Morpholines; Naphthalenes; Oxidants; Random Allocation; Receptor, Cannabinoid, CB2; Scleroderma, Systemic; Signal Transduction; Skin

2010
Involvement of vascular peroxidase 1 in angiotensin II-induced vascular smooth muscle cell proliferation.
    Cardiovascular research, 2011, Jul-01, Volume: 91, Issue:1

    Topics: Analysis of Variance; Angiotensin II; Animals; Aorta, Thoracic; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Enzyme Activation; Enzyme Inhibitors; Extracellular Matrix Proteins; Free Radical Scavengers; Hydrogen Peroxide; Hypertension; Hypochlorous Acid; Male; Mesenteric Arteries; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidases; Peroxidase; Peroxidasin; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA Interference; RNA, Messenger; Signal Transduction; Time Factors

2011
The organotelluride catalyst (PHTE)₂NQ prevents HOCl-induced systemic sclerosis in mouse.
    The Journal of investigative dermatology, 2012, Volume: 132, Issue:4

    Topics: Actins; Animals; Autoantibodies; Cells, Cultured; Disease Models, Animal; DNA Topoisomerases, Type I; Female; Fibroblasts; Fibrosis; Glutathione; Hydrogen Peroxide; Hypochlorous Acid; In Vitro Techniques; Mice; Mice, Inbred BALB C; Naphthoquinones; Nitric Oxide; Organometallic Compounds; Reactive Oxygen Species; Scleroderma, Systemic; Skin; Tellurium

2012
Myeloperoxidase exacerbates secondary injury by generating highly reactive oxygen species and mediating neutrophil recruitment in experimental spinal cord injury.
    Spine, 2012, Jul-15, Volume: 37, Issue:16

    Topics: Animals; Apoptosis; Cytokines; Disease Models, Animal; Female; Flow Cytometry; Gene Expression Regulation; Hypochlorous Acid; Immunohistochemistry; In Situ Nick-End Labeling; Inflammation Mediators; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Neutrophil Infiltration; Oxidative Stress; Peroxidase; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Recovery of Function; Reverse Transcriptase Polymerase Chain Reaction; Spinal Cord; Spinal Cord Injuries; Time Factors

2012
A novel pathway of NADPH oxidase/vascular peroxidase 1 in mediating oxidative injury following ischemia-reperfusion.
    Basic research in cardiology, 2012, Volume: 107, Issue:3

    Topics: Animals; Apoptosis; Caspase 3; Cell Line; Creatine Kinase; Disease Models, Animal; Enzyme Inhibitors; Hemeproteins; Hydrogen Peroxide; Hypochlorous Acid; JNK Mitogen-Activated Protein Kinases; Male; Membrane Glycoproteins; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; NADPH Oxidase 2; NADPH Oxidase 4; NADPH Oxidases; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Peroxidases; Rats; Rats, Sprague-Dawley; RNA Interference; Signal Transduction; Transfection

2012
HOCl oxidation-modified CT26 cell vaccine inhibits colon tumor growth in a mouse model.
    Asian Pacific journal of cancer prevention : APJCP, 2012, Volume: 13, Issue:8

    Topics: Adenocarcinoma; Animals; Antibody-Dependent Cell Cytotoxicity; Apoptosis; Blotting, Western; Cancer Vaccines; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Cytotoxicity, Immunologic; Disease Models, Animal; Female; Flow Cytometry; Hypochlorous Acid; Immunoenzyme Techniques; Immunotherapy; Mice; Mice, Inbred BALB C; Oxidants; RNA, Messenger

2012
Amelioration of systemic fibrosis in mice by angiotensin II receptor blockade.
    Arthritis and rheumatism, 2013, Volume: 65, Issue:5

    Topics: Administration, Oral; Angiotensin II Type 1 Receptor Blockers; Animals; Biomarkers; Biphenyl Compounds; Breath Tests; Disease Models, Animal; Female; Fibrosis; Hypochlorous Acid; Injections, Intradermal; Irbesartan; Lung; Mice; Mice, Inbred BALB C; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidants; Pulmonary Fibrosis; Scleroderma, Systemic; Skin; Tetrazoles; Tyrosine

2013
Development of a rabbit model of tear film instability and evaluation of viscosity of artificial tear preparations.
    Cornea, 2004, Volume: 23, Issue:4

    Topics: Animals; Cellulose; Chondroitin Sulfates; Disease Models, Animal; Dry Eye Syndromes; Hyaluronic Acid; Hypochlorous Acid; Hypromellose Derivatives; Methylcellulose; Ophthalmic Solutions; Rabbits; Tears; Viscosity

2004
Novel model of inflammatory neointima formation reveals a potential role of myeloperoxidase in neointimal hyperplasia.
    American journal of physiology. Heart and circulatory physiology, 2006, Volume: 291, Issue:6

    Topics: Animals; Apoptosis; Atherosclerosis; Carotid Arteries; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Hyperplasia; Hypochlorous Acid; Peroxidase; Rats; Rats, Sprague-Dawley; Time Factors; Tunica Intima; Tunica Media

2006
Intraperitoneal antiseptics in experimental bacterial peritonitis.
    The British journal of surgery, 1984, Volume: 71, Issue:8

    Topics: Animals; Anti-Infective Agents, Local; Chlorhexidine; Disease Models, Animal; Escherichia coli Infections; Hypochlorous Acid; Injections, Intraperitoneal; Male; Mice; Noxythiolin; Peritonitis; Povidone-Iodine; Taurine; Thiadiazines; Time Factors

1984
HOCl effects on tracheal epithelium: conductance and permeability measurements.
    Journal of applied physiology (Bethesda, Md. : 1985), 1995, Volume: 78, Issue:4

    Topics: Aging; Animals; Ascorbic Acid; Cell Membrane Permeability; Disease Models, Animal; Epithelium; Hypochlorous Acid; Ion Transport; Male; Membrane Potentials; Patch-Clamp Techniques; Rabbits; Respiratory Tract Diseases; Trachea

1995
Virulence properties of Pseudomonas aeruginosa lacking the extreme-stress sigma factor AlgU (sigmaE).
    Infection and immunity, 1996, Volume: 64, Issue:7

    Topics: Animals; Bacterial Proteins; Blood Bactericidal Activity; Cystic Fibrosis; Disease Models, Animal; Humans; Hypochlorous Acid; In Vitro Techniques; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mutation; Opportunistic Infections; Pseudomonas aeruginosa; Pseudomonas Infections; Sepsis; Sigma Factor; Virulence

1996
Comparable effects of HOCl and of FMLP-stimulated PMN on the circulation in an isolated lung model.
    American journal of respiratory and critical care medicine, 1997, Volume: 156, Issue:3 Pt 1

    Topics: Animals; Disease Models, Animal; Extravascular Lung Water; Hypochlorous Acid; In Vitro Techniques; Infusions, Intravenous; Microcirculation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Oxidative Stress; Pulmonary Circulation; Pulmonary Wedge Pressure; Rabbits; Reproducibility of Results; Respiratory Distress Syndrome; Time Factors

1997
Protective effect of erdosteine against hypochlorous acid-induced acute lung injury and lipopolysaccharide-induced neutrophilic lung inflammation in mice.
    The Journal of pharmacy and pharmacology, 2000, Volume: 52, Issue:11

    Topics: Administration, Oral; Animals; Bronchitis; Bronchoalveolar Lavage Fluid; Chronic Disease; Disease Models, Animal; Expectorants; Hypochlorous Acid; Inflammation; Lipopolysaccharides; Lung; Male; Mice; Mice, Inbred BALB C; Reactive Oxygen Species; Thioglycolates; Thiophenes; Tumor Necrosis Factor-alpha

2000
Neutrophils employ the myeloperoxidase system to generate antimicrobial brominating and chlorinating oxidants during sepsis.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Oct-09, Volume: 98, Issue:21

    Topics: Animals; Bromine; Chlorine; Disease Models, Animal; HL-60 Cells; Humans; Hypochlorous Acid; Ions; Klebsiella Infections; Klebsiella pneumoniae; Mice; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Oxidants; Peroxidase; Sepsis; Tyrosine

2001
Hypochlorite-modified (lipo)proteins are present in rabbit lesions in response to dietary cholesterol.
    Biochemical and biophysical research communications, 2001, Dec-14, Volume: 289, Issue:4

    Topics: Animals; Arteriosclerosis; Cholesterol, Dietary; Diet, Atherogenic; Disease Models, Animal; Humans; Hyperlipidemias; Hypochlorous Acid; Inflammation; Lipoproteins; Monocytes; Oxidants; Peroxidase; Proteins; Rabbits

2001
Tissue lipid peroxidation and reduced glutathione depletion in hypochlorite-induced lung injury.
    Chest, 2002, Volume: 121, Issue:2

    Topics: Animals; Capillary Permeability; Disease Models, Animal; Glutathione; Hypochlorous Acid; In Vitro Techniques; Lipid Peroxidation; Lung; Neutrophils; Pulmonary Circulation; Pulmonary Edema; Rabbits; Respiratory Distress Syndrome

2002