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hypochlorous acid and Arteriosclerosis

hypochlorous acid has been researched along with Arteriosclerosis in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's12 (34.29)18.2507
2000's23 (65.71)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Davies, MJ; Linton, SM; Woods, AA1
Beisiegel, U; Bräsen, JH; Häkkinen, T; Malle, E; Ylä-Herttuala, S1
Jacobs, JD; Jennings, LK; Yang, J; Zhang, C1
Fisher, MT; Khor, HK; Schöneich, C1
Azuma, J; Ito, T1
Hazen, SL1
McCarty, MF1
Anantharamaiah, GM; Bergt, C; Brunzell, J; Byun, J; Chait, A; Fu, X; Geary, RL; Heinecke, JW; McDonald, TO; O'Brien, K; Oram, JF; Pennathur, S; Singh, P1
Daugherty, A; Dunn, JL; Heinecke, JW; Rateri, DL1
Arnold, L; Flowers, D; Hazell, LJ; Malle, E; Stocker, R; Waeg, G1
Hazen, SL; Heinecke, JW1
Heinecke, JW1
Crowley, JR; Hazen, SL; Heinecke, JW; Mueller, DM1
Aviram, M; Coleman, R; Hayek, T; Maor, I1
Bussfeld, D; Gemsa, D; Gröne, HJ; Kaufmann, A; Sprenger, H; Woenckhaus, C1
Briviba, K; Panasenko, OM; Panasenko, OO; Sies, H1
Auer, H; Fabjan, JS; Guttenberger, H; Hayn, M; Horakova, L; Jerlich, A; Leis, HJ; Schaur, RJ; Smirnova, AV; Tatzber, F; Tschabuschnig, S; Waeg, G1
Davies, MJ; Dean, RT; Fu, S; Stocker, R1
Hazen, SL; Hegele, RA; Heinecke, JW; Huff, MW; Miller, DB; Whitman, SC1
Jerlich, A; Pitt, AR; Schaur, RJ; Spickett, CM1
Fabjan, JS; Giessauf, A; Horakova, L; Jerlich, A; Jürgens, G; Schaur, RJ1
Gröne, EF; Gröne, HJ; Malle, E; Sattler, W; Schreiber, R; Waeg, G1
Brunner, M; Friedl, R; Koller, E; Moeslinger, T; Spieckermann, PG; Volf, I1
Artmann, GM; Gorbatenkova, EA; Panasenko, OM1
Fritz, G; Glatter, O; Hammel, M; Jerlich, A; Kharrazi, H; Schaur, RJ; Tschabuschnig, S1
Descamps-Latscha, B; Drüeke, TB; Lacour, B; Massy, ZA; Nguyen Khoa, T; Witko-Sarsat, V1
Anderson, MM; Brennan, ML; Crowley, JR; Hazen, SL; Heinecke, JW; Jacob, JS; Lim, LL; Lusis, AJ; Mehta, AC; Qu, XD; Shi, W; Shih, DM; Wang, X1
Heinecke, JW; Libby, P; Okada, Y; Sugiyama, S; Sukhova, GK; Virmani, R1
Abuja, PM; Fabjan, JS; Schaur, RJ; Sevanian, A1
Fu, X; Heinecke, JW; Kassim, SY; Parks, WC1
Panasenko, OM; Sergienko, VI1
Nauseef, WM1
Baernthaler, G; Hazell, LJ; Stocker, R1
Gröne, HJ; Malle, E; Sattler, W; Thiery, J; Wäg, G1
Dunster, C; Halliwell, B; Jenner, AM; Mann, GE; Ruiz, JE; Siow, RC1

Reviews

5 review(s) available for hypochlorous acid and Arteriosclerosis

ArticleYear
[Taurine is a possible anti-atherosclerotic agent].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2004, Volume: 123, Issue:5

    Topics: Animals; Antioxidants; Arteriosclerosis; Cholesterol; Endothelium, Vascular; Free Radical Scavengers; Humans; Hypercholesterolemia; Hypochlorous Acid; Lipid Peroxidation; Lipoproteins, LDL; Macrophages; Neutrophils; NF-kappa B; Peroxidase; Taurine

2004
Pathways for oxidation of low density lipoprotein by myeloperoxidase: tyrosyl radical, reactive aldehydes, hypochlorous acid and molecular chlorine.
    BioFactors (Oxford, England), 1997, Volume: 6, Issue:2

    Topics: Aldehydes; Animals; Arteriosclerosis; Chlorine; Cholesterol, LDL; Free Radicals; Humans; Hypochlorous Acid; Lipoproteins, LDL; Macrophages; Oxidants; Oxidation-Reduction; Peroxidase; Tyrosine

1997
Role of oxidized low-density lipoprotein in the atherosclerosis of uremia.
    Kidney international. Supplement, 2001, Volume: 78

    Topics: Arteriosclerosis; Cell Line; Humans; Hypochlorous Acid; In Vitro Techniques; Kidney Failure, Chronic; Lipid Peroxidation; Lipoproteins, LDL; Oxidation-Reduction; Uremia

2001
Hypochlorite, oxidative modification of plasma lipoproteins, and atherosclerosis.
    Bulletin of experimental biology and medicine, 2001, Volume: 131, Issue:5

    Topics: Animals; Arteriosclerosis; Free Radicals; Humans; Hypochlorous Acid; Lipid Peroxidation; Lipoproteins; Models, Biological; Models, Chemical; Monocytes; Oxygen

2001
Contributions of myeloperoxidase to proinflammatory events: more than an antimicrobial system.
    International journal of hematology, 2001, Volume: 74, Issue:2

    Topics: Animals; Anti-Infective Agents; Arteriosclerosis; Central Nervous System Diseases; Humans; Hypochlorous Acid; Inflammation; Peroxidase

2001

Other Studies

30 other study(ies) available for hypochlorous acid and Arteriosclerosis

ArticleYear
Detection of HOCl-mediated protein oxidation products in the extracellular matrix of human atherosclerotic plaques.
    The Biochemical journal, 2003, Mar-01, Volume: 370, Issue:Pt 2

    Topics: Amino Acids; Animals; Aorta; Arteriosclerosis; Chromatography, High Pressure Liquid; Extracellular Matrix; Humans; Hypochlorous Acid; Oxidation-Reduction; Swine

2003
Patterns of oxidized epitopes, but not NF-kappa B expression, change during atherogenesis in WHHL rabbits.
    Atherosclerosis, 2003, Volume: 166, Issue:1

    Topics: Aldehydes; Animals; Arteriosclerosis; Epitopes; Hypochlorous Acid; Immunohistochemistry; Malondialdehyde; Nitrates; Oxidation-Reduction; Rabbits

2003
Interaction of myeloperoxidase with vascular NAD(P)H oxidase-derived reactive oxygen species in vasculature: implications for vascular diseases.
    American journal of physiology. Heart and circulatory physiology, 2003, Volume: 285, Issue:6

    Topics: Animals; Arteriosclerosis; Cholesterol, LDL; Endothelium, Vascular; Hydrogen Peroxide; Hypochlorous Acid; Male; NADPH Oxidases; Peroxidase; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Vasculitis

2003
Potential role of methionine sulfoxide in the inactivation of the chaperone GroEL by hypochlorous acid (HOCl) and peroxynitrite (ONOO-).
    The Journal of biological chemistry, 2004, May-07, Volume: 279, Issue:19

    Topics: Amino Acid Sequence; Arteriosclerosis; Chaperonin 60; Chromatography; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Humans; Hydrolysis; Hypochlorous Acid; Mass Spectrometry; Methionine; Methionine Sulfoxide Reductases; Molecular Chaperones; Molecular Sequence Data; Oxidants; Oxidoreductases; Oxygen; Peptides; Peroxynitrous Acid; Phagocytes; Protein Binding; Time Factors; Trypsin; Tyrosine

2004
Myeloperoxidase and plaque vulnerability.
    Arteriosclerosis, thrombosis, and vascular biology, 2004, Volume: 24, Issue:7

    Topics: Arteriosclerosis; Coronary Thrombosis; Death, Sudden, Cardiac; Disease Progression; Endothelium, Vascular; Female; Glutathione; Humans; Hypochlorous Acid; Inflammation Mediators; Macrophages; Male; Models, Biological; Peroxidase; Rupture, Spontaneous; Thrombophilia; Thromboplastin

2004
Supplementary taurine may stabilize atheromatous plaque by antagonizing the activation of metalloproteinases by hypochlorous acid.
    Medical hypotheses, 2004, Volume: 63, Issue:3

    Topics: Arteriosclerosis; Carotid Stenosis; Dietary Supplements; Enzyme Activation; Humans; Hypochlorous Acid; Metalloproteases; Models, Biological; Taurine

2004
The myeloperoxidase product hypochlorous acid oxidizes HDL in the human artery wall and impairs ABCA1-dependent cholesterol transport.
    Proceedings of the National Academy of Sciences of the United States of America, 2004, Aug-31, Volume: 101, Issue:35

    Topics: Amino Acid Sequence; Apolipoprotein A-I; Arteries; Arteriosclerosis; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Cholesterol, HDL; Chromatography, Liquid; Humans; Hypochlorous Acid; Mass Spectrometry; Molecular Sequence Data; Peroxidase; Tyrosine

2004
Myeloperoxidase, a catalyst for lipoprotein oxidation, is expressed in human atherosclerotic lesions.
    The Journal of clinical investigation, 1994, Volume: 94, Issue:1

    Topics: Arteriosclerosis; Free Radicals; Humans; Hypochlorous Acid; Immunohistochemistry; Lipoproteins; Macrophages; Peroxidase

1994
Presence of hypochlorite-modified proteins in human atherosclerotic lesions.
    The Journal of clinical investigation, 1996, Mar-15, Volume: 97, Issue:6

    Topics: Arteriosclerosis; Humans; Hypochlorous Acid; Immunohistochemistry; Lipoproteins, LDL; Oxidation-Reduction; Proteins

1996
3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima.
    The Journal of clinical investigation, 1997, May-01, Volume: 99, Issue:9

    Topics: Aorta; Apolipoproteins B; Arteriosclerosis; Biomarkers; Chlorine; Humans; Hypochlorous Acid; Lipoproteins; Lipoproteins, LDL; Oxidation-Reduction; Peroxidase; Phagocytes; Tyrosine

1997
Mass spectrometric quantification of 3-chlorotyrosine in human tissues with attomole sensitivity: a sensitive and specific marker for myeloperoxidase-catalyzed chlorination at sites of inflammation.
    Free radical biology & medicine, 1997, Volume: 23, Issue:6

    Topics: Analysis of Variance; Aorta; Arteriosclerosis; Biomarkers; Calibration; Carbon; Carbon Isotopes; Catalysis; Chlorine; Female; Gas Chromatography-Mass Spectrometry; Humans; Hypochlorous Acid; Inflammation; Lipoproteins, LDL; Male; Peroxidase; Sensitivity and Specificity; Tyrosine

1997
Plasma LDL oxidation leads to its aggregation in the atherosclerotic apolipoprotein E-deficient mice.
    Arteriosclerosis, thrombosis, and vascular biology, 1997, Volume: 17, Issue:11

    Topics: Amidines; Animals; Antioxidants; Aorta; Apolipoproteins E; Arteriosclerosis; Copper; Free Radicals; Hypochlorous Acid; Lipoproteins, LDL; Macrophages; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Knockout; Oxidants; Oxidation-Reduction; Particle Size; Tumor Cells, Cultured

1997
Hypochlorite-modified LDL: chemotactic potential and chemokine induction in human monocytes.
    Clinical immunology and immunopathology, 1998, Volume: 86, Issue:1

    Topics: Arteriosclerosis; Chemokine CCL2; Chemotactic Factors; Chemotaxis, Leukocyte; Gene Expression Regulation; Humans; Hypochlorous Acid; Interleukin-8; Lipoproteins, LDL; Monocytes; Neutrophils; RNA, Messenger

1998
Hypochlorite destroys carotenoids in low density lipoproteins thus decreasing their resistance to peroxidative modification.
    Biochemistry. Biokhimiia, 1997, Volume: 62, Issue:10

    Topics: Arteriosclerosis; Carotenoids; Chromatography, High Pressure Liquid; Copper; Free Radical Scavengers; Humans; Hypochlorous Acid; Kinetics; Lipid Peroxidation; Lipoproteins, LDL; Molecular Structure; Spectrophotometry

1997
Human low density lipoprotein as a target of hypochlorite generated by myeloperoxidase.
    Free radical biology & medicine, 1998, Volume: 24, Issue:7-8

    Topics: Adult; Apolipoprotein B-100; Apolipoproteins B; Arteriosclerosis; Binding Sites; Female; Free Radicals; Humans; Hypochlorous Acid; In Vitro Techniques; Kinetics; Lipoproteins, LDL; Magnetic Resonance Spectroscopy; Male; Peroxidase; Reactive Oxygen Species; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Thiobarbituric Acid Reactive Substances; Tryptophan

1998
Evidence for roles of radicals in protein oxidation in advanced human atherosclerotic plaque.
    The Biochemical journal, 1998, Aug-01, Volume: 333 ( Pt 3)

    Topics: Adult; Amino Acids; Arteriosclerosis; Blood Proteins; Dihydroxyphenylalanine; Female; Humans; Hydroxides; Hydroxyl Radical; Hypochlorous Acid; Male; Middle Aged; Oxidation-Reduction; Peroxides; Proteins; Serum Albumin, Bovine; Tunica Intima

1998
Modification of type III VLDL, their remnants, and VLDL from ApoE-knockout mice by p-hydroxyphenylacetaldehyde, a product of myeloperoxidase activity, causes marked cholesteryl ester accumulation in macrophages.
    Arteriosclerosis, thrombosis, and vascular biology, 1999, Volume: 19, Issue:5

    Topics: Acetaldehyde; Animals; Apolipoproteins E; Arteriosclerosis; Cell Line; Cholesterol Esters; Esterification; Humans; Hyperlipoproteinemia Type III; Hypochlorous Acid; Interferon-gamma; Lipoprotein Lipase; Lipoproteins, VLDL; Macrophages; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidation-Reduction; Peroxidase; Phenol; Poly I; Receptors, Immunologic; Receptors, Lipoprotein; Receptors, Scavenger; Scavenger Receptors, Class A; Scavenger Receptors, Class B; Sterol O-Acyltransferase; Triglycerides; Tyrosine

1999
Pathways of phospholipid oxidation by HOCl in human LDL detected by LC-MS.
    Free radical biology & medicine, 2000, Mar-01, Volume: 28, Issue:5

    Topics: Adult; Arteriosclerosis; Chlorohydrins; Chromatography, High Pressure Liquid; Female; Free Radicals; Humans; Hypochlorous Acid; In Vitro Techniques; Lipid Peroxides; Lipoproteins, LDL; Male; Mass Spectrometry; Oxidation-Reduction; Peroxidase; Phospholipids

2000
Correlation of low-density lipoprotein modification by myeloperoxidase with hypochlorous acid formation.
    International journal of clinical & laboratory research, 1999, Volume: 29, Issue:4

    Topics: Adult; Arteriosclerosis; Chlorides; Cholesterol, LDL; Female; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hypochlorous Acid; Kinetics; Male; Oxidants; Oxidative Stress; Peroxidase

1999
Immunohistochemical evidence for the myeloperoxidase/H2O2/halide system in human atherosclerotic lesions: colocalization of myeloperoxidase and hypochlorite-modified proteins.
    European journal of biochemistry, 2000, Volume: 267, Issue:14

    Topics: Aged; Antibodies, Monoclonal; Aorta; Arteriosclerosis; Blotting, Western; Dose-Response Relationship, Immunologic; Electrophoresis, Polyacrylamide Gel; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Epitopes; Female; Femoral Artery; Humans; Hydrogen Peroxide; Hypochlorous Acid; Immunohistochemistry; Lipoproteins, LDL; Male; Middle Aged; Oxygen; Peroxidase; Tibial Arteries; Ultracentrifugation

2000
Inhibition of inducible nitric oxide synthesis by oxidized lipoprotein(a) in a murine macrophage cell line.
    FEBS letters, 2000, Jul-28, Volume: 478, Issue:1-2

    Topics: Animals; Arginine; Arteriosclerosis; Biological Transport; Blotting, Western; Cell Line; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Hypochlorous Acid; Interferon-gamma; Lipopolysaccharides; Lipoprotein(a); Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidation-Reduction; RNA, Messenger

2000
Hypochlorous acid and human blood low density lipoproteins modified by hypochlorous acid increase erythrocyte adhesion to endothelial cells.
    Membrane & cell biology, 2000, Volume: 13, Issue:4

    Topics: Arteriosclerosis; Cell Adhesion; Cholesterol; Dose-Response Relationship, Drug; Endothelium, Vascular; Erythrocytes; Humans; Hypochlorous Acid; Lipid Peroxidation; Lipoproteins, LDL

2000
Comparison of HOCl traps with myeloperoxidase inhibitors in prevention of low density lipoprotein oxidation.
    Biochimica et biophysica acta, 2000, Aug-31, Volume: 1481, Issue:1

    Topics: Arteriosclerosis; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluorescence; Glycine; Humans; Hydroxamic Acids; Hydroxybenzoates; Hypochlorous Acid; Lipoproteins, LDL; Methionine; Neutrophils; Peroxidase; Potassium Cyanide; Salicylamides; Sodium Azide; Taurine; Tryptophan

2000
Increased atherosclerosis in myeloperoxidase-deficient mice.
    The Journal of clinical investigation, 2001, Volume: 107, Issue:4

    Topics: Animals; Arteriosclerosis; Candida albicans; Humans; Hypochlorous Acid; Mice; Mice, Inbred C57BL; Neutrophils; Oxidation-Reduction; Peroxidase; Phagocytes; Tyrosine

2001
Macrophage myeloperoxidase regulation by granulocyte macrophage colony-stimulating factor in human atherosclerosis and implications in acute coronary syndromes.
    The American journal of pathology, 2001, Volume: 158, Issue:3

    Topics: Arteriosclerosis; CD40 Antigens; Cell Differentiation; Cells, Cultured; Cholesterol; Gene Expression Regulation; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Hypochlorous Acid; Lysophosphatidylcholines; Macrophages; Monocytes; Myocardial Infarction; Peroxidase; Phenotype; Reactive Oxygen Species; Syndrome; Tunica Intima

2001
Hypochlorite induces the formation of LDL(-), a potentially atherogenic low density lipoprotein subspecies.
    FEBS letters, 2001, Jun-15, Volume: 499, Issue:1-2

    Topics: Arteriosclerosis; Chloramines; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Humans; Hypochlorous Acid; Lipoproteins, LDL; Methionine; Oxidants; Oxidation-Reduction; Plasma; Static Electricity; Time Factors

2001
Hypochlorous acid oxygenates the cysteine switch domain of pro-matrilysin (MMP-7). A mechanism for matrix metalloproteinase activation and atherosclerotic plaque rupture by myeloperoxidase.
    The Journal of biological chemistry, 2001, Nov-02, Volume: 276, Issue:44

    Topics: Amino Acid Sequence; Arteriosclerosis; Chromatography, High Pressure Liquid; Cysteine; Enzyme Activation; Enzyme Precursors; Hydrogen Peroxide; Hypochlorous Acid; Matrix Metalloproteinase 7; Molecular Sequence Data; Oxygen; Peroxidase; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet

2001
Correlation between intima-to-media ratio, apolipoprotein B-100, myeloperoxidase, and hypochlorite-oxidized proteins in human atherosclerosis.
    Free radical biology & medicine, 2001, Nov-15, Volume: 31, Issue:10

    Topics: Adult; Apolipoprotein B-100; Apolipoproteins B; Arteriosclerosis; Disease Progression; Female; Humans; Hypochlorous Acid; Iliac Artery; Lipoproteins, LDL; Male; Middle Aged; Oxidation-Reduction; Peroxidase; Tunica Intima; Tunica Media

2001
Hypochlorite-modified (lipo)proteins are present in rabbit lesions in response to dietary cholesterol.
    Biochemical and biophysical research communications, 2001, Dec-14, Volume: 289, Issue:4

    Topics: Animals; Arteriosclerosis; Cholesterol, Dietary; Diet, Atherogenic; Disease Models, Animal; Humans; Hyperlipidemias; Hypochlorous Acid; Inflammation; Lipoproteins; Monocytes; Oxidants; Peroxidase; Proteins; Rabbits

2001
Vitamin C protects against hypochlorous Acid-induced glutathione depletion and DNA base and protein damage in human vascular smooth muscle cells.
    Arteriosclerosis, thrombosis, and vascular biology, 2002, Apr-01, Volume: 22, Issue:4

    Topics: Adenosine Triphosphate; Arteriosclerosis; Ascorbic Acid; Cell Survival; Cells, Cultured; DNA; DNA Damage; Glutathione; Humans; Hypochlorous Acid; Muscle, Smooth, Vascular; Umbilical Arteries

2002