Page last updated: 2024-08-22

hypochlorous acid and Agranulocytosis

hypochlorous acid has been researched along with Agranulocytosis in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (62.50)18.2507
2000's3 (37.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Iverson, S; Uetrecht, JP; Zahid, N1
Ma, HM; MacKnight, E; McClelland, R; Uetrecht, JP1
Uetrecht, JP; Whitfield, D; Zahid, N1
Uetrecht, JP1
Fu, JM; Rakhit, S; Tehim, A; Uetrecht, J; Zahid, N1
Gardner, I; MacCrimmon, D; Uetrecht, JP; Zahid, N1
Gardner, I; Lai, WG; Uetrecht, JP; Zahid, N1
Liu, ZC; Uetrecht, JP1

Reviews

1 review(s) available for hypochlorous acid and Agranulocytosis

ArticleYear
Reactive metabolites and agranulocytosis.
    European journal of haematology. Supplementum, 1996, Volume: 60

    Topics: Agranulocytosis; Aminopyrine; Clozapine; Humans; Hypochlorous Acid; Neutrophil Activation

1996

Other Studies

7 other study(ies) available for hypochlorous acid and Agranulocytosis

ArticleYear
Predicting drug-induced agranulocytosis: characterizing neutrophil-generated metabolites of a model compound, DMP 406, and assessing the relevance of an in vitro apoptosis assay for identifying drugs that may cause agranulocytosis.
    Chemico-biological interactions, 2002, Nov-10, Volume: 142, Issue:1-2

    Topics: Agranulocytosis; Antipsychotic Agents; Apoptosis; Benzodiazepines; Chromatography, High Pressure Liquid; Chromatography, Liquid; Clozapine; Cyanides; Horseradish Peroxidase; Humans; Hydrogen Peroxide; Hypochlorous Acid; Mass Spectrometry; Mianserin; Neutrophils; Nuclear Medicine; Olanzapine; Pirenzepine

2002
Oxidation of aminopyrine by hypochlorite to a reactive dication: possible implications for aminopyrine-induced agranulocytosis.
    Chemical research in toxicology, 1995, Volume: 8, Issue:2

    Topics: Agranulocytosis; Aminopyrine; Cations; Deuterium; Humans; Hypochlorous Acid; Isotopes; Kinetics; Magnetic Resonance Spectroscopy; Mass Spectrometry; Neutrophils; Oxidation-Reduction

1995
Metabolism of vesnarinone by activated neutrophils: implications for vesnarinone-induced agranulocytosis.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 270, Issue:3

    Topics: Agranulocytosis; Albumins; Cardiotonic Agents; Chromatography, High Pressure Liquid; Glutathione; Humans; Hydrogen Peroxide; Hypochlorous Acid; In Vitro Techniques; Influenza Vaccines; Magnetic Resonance Spectroscopy; Mass Spectrometry; Neutrophil Activation; Neutrophils; Oxidation-Reduction; Peroxidase; Protein Binding; Pyrazines; Quinolines

1994
Structural features associated with reactive metabolite formation in clozapine analogues.
    Chemico-biological interactions, 1997, May-02, Volume: 104, Issue:2-3

    Topics: Agranulocytosis; Antipsychotic Agents; Benzodiazepines; Binding Sites; Chromatography, High Pressure Liquid; Chromatography, Liquid; Clozapine; Dibenzazepines; Glutathione; Granulocytes; Humans; Hydrogen Peroxide; Hypochlorous Acid; Lymphocyte Activation; Mass Spectrometry; Neutrophils; Nitrogen; Olanzapine; Oxidation-Reduction; Peroxidase; Pirenzepine; Structure-Activity Relationship

1997
A comparison of the oxidation of clozapine and olanzapine to reactive metabolites and the toxicity of these metabolites to human leukocytes.
    Molecular pharmacology, 1998, Volume: 53, Issue:6

    Topics: Agranulocytosis; Antipsychotic Agents; Benzodiazepines; Clozapine; HL-60 Cells; Humans; Hypochlorous Acid; Neutrophils; Olanzapine; Oxidation-Reduction; Pirenzepine

1998
Bioactivation and covalent binding of hydroxyfluperlapine in human neutrophils: implications for fluperlapine-induced agranulocytosis.
    Drug metabolism and disposition: the biological fate of chemicals, 2000, Volume: 28, Issue:3

    Topics: Acetylcysteine; Agranulocytosis; Binding, Competitive; Clozapine; Dibenzazepines; Glutathione; Hemocyanins; Humans; Hypochlorous Acid; Immune Sera; Immunoblotting; Neutrophil Activation; Neutrophils; Oxidation-Reduction; Peroxidase; Protein Binding

2000
Metabolism of ticlopidine by activated neutrophils: implications for ticlopidine-induced agranulocytosis.
    Drug metabolism and disposition: the biological fate of chemicals, 2000, Volume: 28, Issue:7

    Topics: Agranulocytosis; Anti-Inflammatory Agents, Non-Steroidal; Glutathione; Humans; Hypochlorous Acid; Neutrophil Activation; Neutrophils; Oxidation-Reduction; Ticlopidine

2000