hypericum and Diabetes-Mellitus--Type-2

hypericum has been researched along with Diabetes-Mellitus--Type-2* in 2 studies

Reviews

1 review(s) available for hypericum and Diabetes-Mellitus--Type-2

Article	Year
Protective Role of St. John's Wort and Its Components Hyperforin and Hypericin against Diabetes through Inhibition of Inflammatory Signaling: Evidence from In Vitro and In Vivo Studies. International journal of molecular sciences, 2020, Oct-30, Volume: 21, Issue:21 Topics: Animals; Diabetes Mellitus, Type 2; Humans; Hypericum; Inflammation; Phloroglucinol; Phytotherapy; Plant Extracts; Terpenes	2020

Other Studies

1 other study(ies) available for hypericum and Diabetes-Mellitus--Type-2

Article	Year
Rapid screening of α-glucosidase inhibitors in Hypericum perforatum L. using bio-affinity chromatography coupled with UPLC/MS. Biomedical chromatography : BMC, 2023, Volume: 37, Issue:2 α-glucosidase inhibitors (AGIs) are widely used for the treatment of type 2 diabetes, but their side effects have made it to develop novel and alternative AGIs immediately. In this study, the extract of Hypericum perforatum L. (HPE) has been confirmed to have α-glucosidase inhibitory activity in vitro and in vivo. Seven active compounds, rutin, hyperoside, isoquercitrin, avicularin, quercitrin, quercetin, and biapigenin, were screened based on a bio-affinity chromatography column with α-glucosidase enzyme-conjugated solid phase and UPLC/MS, which exhibited excellent α-glycosidase inhibitory effects by the determined IC Topics: alpha-Glucosidases; Chromatography, Affinity; Diabetes Mellitus, Type 2; Glycoside Hydrolase Inhibitors; Hypericum; Mass Spectrometry; Molecular Docking Simulation; Plant Extracts; Plant Oils	2023

Article

Year

Rapid screening of α-glucosidase inhibitors in Hypericum perforatum L. using bio-affinity chromatography coupled with UPLC/MS.

Biomedical chromatography : BMC, 2023, Volume: 37, Issue:2

α-glucosidase inhibitors (AGIs) are widely used for the treatment of type 2 diabetes, but their side effects have made it to develop novel and alternative AGIs immediately. In this study, the extract of Hypericum perforatum L. (HPE) has been confirmed to have α-glucosidase inhibitory activity in vitro and in vivo. Seven active compounds, rutin, hyperoside, isoquercitrin, avicularin, quercitrin, quercetin, and biapigenin, were screened based on a bio-affinity chromatography column with α-glucosidase enzyme-conjugated solid phase and UPLC/MS, which exhibited excellent α-glycosidase inhibitory effects by the determined IC

Topics: alpha-Glucosidases; Chromatography, Affinity; Diabetes Mellitus, Type 2; Glycoside Hydrolase Inhibitors; Hypericum; Mass Spectrometry; Molecular Docking Simulation; Plant Extracts; Plant Oils

2023