Page last updated: 2024-10-28

hypericin and Myocardial Infarction

hypericin has been researched along with Myocardial Infarction in 8 studies

Myocardial Infarction: NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).

Research Excerpts

ExcerptRelevanceReference
"We determined whether sodium cholate (NaCh) could act as a solubilizing agent for the necrosis avid iodine-123-labeled hypericin ((123)I-Hyp) and investigated biodistribution and targetability of this formulation in rabbits with acute myocardial infarction (AMI)."7.81Sodium cholate, a solubilizing agent for the necrosis avid radioiodinated hypericin in rabbits with acute myocardial infarction. ( Cona, MM; Feng, Y; Li, Y; Ni, Y; Oyen, R; Verbruggen, A; Zhang, J, 2015)
"Mono-[(123)I]iodohypericin ([(123)I]MIH) has been reported to have high avidity for necrosis."7.74Non-invasive detection and quantification of acute myocardial infarction in rabbits using mono-[123I]iodohypericin microSPECT. ( Bormans, G; Feng, Y; Fonge, H; Mortelmans, L; Ni, Y; Nuyts, J; Verbruggen, A; Vunckx, K; Wang, H, 2008)
"The results suggest that hypericin derivatives may serve as powerful necrosis-avid diagnostic agents for assessment of tissue viability."7.73First preclinical evaluation of mono-[123I]iodohypericin as a necrosis-avid tracer agent. ( Bormans, GM; Chen, F; de Witte, PA; Huyghe, D; Marchal, G; Mortelmans, L; Ni, Y; Nuyts, J; Verbeke, K; Verbruggen, AM, 2006)
"Hypericin was radiolabeled with I using iodogen as oxidant, and (99m)Tc-Sestamibi was prepared from a commercial kit and radioactive sodium pertechnetate."5.39Comparative study of iodine-123-labeled hypericin and (99m)Tc-labeled hexakis [2-methoxy isobutyl isonitrile] in a rabbit model of myocardial infarction. ( Chen, F; Cona, MM; Feng, Y; Gheysens, O; Li, Y; Ni, Y; Nuyts, J; Oyen, R; Rezaei, A; Van Slambrouck, K; Verbruggen, A; Vunckx, K; Zhou, L, 2013)
"We determined whether sodium cholate (NaCh) could act as a solubilizing agent for the necrosis avid iodine-123-labeled hypericin ((123)I-Hyp) and investigated biodistribution and targetability of this formulation in rabbits with acute myocardial infarction (AMI)."3.81Sodium cholate, a solubilizing agent for the necrosis avid radioiodinated hypericin in rabbits with acute myocardial infarction. ( Cona, MM; Feng, Y; Li, Y; Ni, Y; Oyen, R; Verbruggen, A; Zhang, J, 2015)
"Mono-[(123)I]iodohypericin ([(123)I]MIH) has been reported to have high avidity for necrosis."3.74Non-invasive detection and quantification of acute myocardial infarction in rabbits using mono-[123I]iodohypericin microSPECT. ( Bormans, G; Feng, Y; Fonge, H; Mortelmans, L; Ni, Y; Nuyts, J; Verbruggen, A; Vunckx, K; Wang, H, 2008)
"The results suggest that hypericin derivatives may serve as powerful necrosis-avid diagnostic agents for assessment of tissue viability."3.73First preclinical evaluation of mono-[123I]iodohypericin as a necrosis-avid tracer agent. ( Bormans, GM; Chen, F; de Witte, PA; Huyghe, D; Marchal, G; Mortelmans, L; Ni, Y; Nuyts, J; Verbeke, K; Verbruggen, AM, 2006)
"Hypericin was radiolabeled with I using iodogen as oxidant, and (99m)Tc-Sestamibi was prepared from a commercial kit and radioactive sodium pertechnetate."1.39Comparative study of iodine-123-labeled hypericin and (99m)Tc-labeled hexakis [2-methoxy isobutyl isonitrile] in a rabbit model of myocardial infarction. ( Chen, F; Cona, MM; Feng, Y; Gheysens, O; Li, Y; Ni, Y; Nuyts, J; Oyen, R; Rezaei, A; Van Slambrouck, K; Verbruggen, A; Vunckx, K; Zhou, L, 2013)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (37.50)29.6817
2010's4 (50.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Salarian, M1
Cona, MM2
Feng, Y4
Li, Y2
Chen, F2
Vunckx, K2
Zhou, L1
Van Slambrouck, K1
Rezaei, A1
Gheysens, O1
Nuyts, J3
Verbruggen, A4
Oyen, R2
Ni, Y6
Zhang, J3
Li, J2
Yang, S2
Jiang, C2
Zhang, D1
Jin, Q2
Wang, Q2
Wang, C2
Yin, Z2
Song, S2
Chen, L1
De Saint-Hubert, M1
Prinsen, K1
Mortelmans, L3
Mottaghy, FM1
Huyghe, D1
Verbeke, K1
de Witte, PA1
Marchal, G1
Verbruggen, AM1
Bormans, GM1
Fonge, H1
Wang, H1
Bormans, G1

Reviews

1 review available for hypericin and Myocardial Infarction

ArticleYear
Molecular imaging of cell death.
    Methods (San Diego, Calif.), 2009, Volume: 48, Issue:2

    Topics: Animals; Annexin A5; Anthracenes; Antibodies, Monoclonal; Apoptosis; Bacteriocins; Cell Death; Gluca

2009

Other Studies

7 other studies available for hypericin and Myocardial Infarction

ArticleYear
The promise of hypericin: a tracer for acute myocardial infarction.
    Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2022, Volume: 29, Issue:6

    Topics: Anthracenes; Humans; Myocardial Infarction; Perylene

2022
Comparative study of iodine-123-labeled hypericin and (99m)Tc-labeled hexakis [2-methoxy isobutyl isonitrile] in a rabbit model of myocardial infarction.
    Journal of cardiovascular pharmacology, 2013, Volume: 62, Issue:3

    Topics: Animals; Anthracenes; Autoradiography; Coronary Circulation; Coronary Vessels; Disease Models, Anima

2013
Sodium cholate, a solubilizing agent for the necrosis avid radioiodinated hypericin in rabbits with acute myocardial infarction.
    Drug delivery, 2015, Volume: 22, Issue:3

    Topics: Animals; Anthracenes; Autoradiography; Disease Models, Animal; Gamma Cameras; Heart; Iodine Radioiso

2015
Synthesis and Preclinical Evaluation of Radioiodinated Hypericin Dicarboxylic Acid as a Necrosis Avid Agent in Rat Models of Induced Hepatic, Muscular, and Myocardial Necroses.
    Molecular pharmaceutics, 2016, Jan-04, Volume: 13, Issue:1

    Topics: Animals; Anthracenes; Iodine Radioisotopes; Liver; Muscle, Skeletal; Myocardial Infarction; Myocardi

2016
Discovery of Radioiodinated Monomeric Anthraquinones as a Novel Class of Necrosis Avid Agents for Early Imaging of Necrotic Myocardium.
    Scientific reports, 2016, Feb-16, Volume: 6

    Topics: Animals; Anthracenes; Anthraquinones; Chromatography, High Pressure Liquid; Iodine Radioisotopes; Ma

2016
First preclinical evaluation of mono-[123I]iodohypericin as a necrosis-avid tracer agent.
    European journal of nuclear medicine and molecular imaging, 2006, Volume: 33, Issue:5

    Topics: Animals; Anthracenes; Drug Evaluation, Preclinical; Heart; Liver; Metabolic Clearance Rate; Myocardi

2006
Non-invasive detection and quantification of acute myocardial infarction in rabbits using mono-[123I]iodohypericin microSPECT.
    European heart journal, 2008, Volume: 29, Issue:2

    Topics: Animals; Anthracenes; Disease Models, Animal; Drug Evaluation, Preclinical; Heart; Iodine Radioisoto

2008