hypericin has been researched along with Malignant Melanoma in 9 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Photodynamic-induced cytotoxicity by hypericin (HYP) was studied on three human melanoma cell lines: one pigmented cell line (G361) and two amelanotic cell lines (M18 and M6)." | 7.69 | Photodynamic effects of hypericin on lipid peroxidation and antioxidant status in melanoma cells. ( Favier, A; Hadjur, C; Jardon, P; Parat, MO; Richard, MJ, 1996) |
| "Hypericin was taken up by all melanoma cells and partially co-localized to the endoplasmic reticulum, mitochondria, lysosomes and melanosomes, but not the nucleus." | 5.40 | St John's Wort (Hypericum perforatum L.) photomedicine: hypericin-photodynamic therapy induces metastatic melanoma cell death. ( Davids, LM; Kleemann, B; Lang, D; Loos, B; Scriba, TJ, 2014) |
| "Melanoma is the main cause of death in skin cancers." | 5.38 | Depigmentation in melanomas increases the efficacy of hypericin-mediated photodynamic-induced cell death. ( Davids, LM; Sharma, KV, 2012) |
| " This would result in toxic melanin precursors (of an indolic and phenolic nature) leaking into the cytoplasm which in turn leads to cell death." | 5.35 | Hypericin phototoxicity induces different modes of cell death in melanoma and human skin cells. ( Davids, LM; Kacerovská, D; Kidson, SH; Kleemann, B; Pizinger, K, 2008) |
| "Photodynamic-induced cytotoxicity by hypericin (HYP) was studied on three human melanoma cell lines: one pigmented cell line (G361) and two amelanotic cell lines (M18 and M6)." | 3.69 | Photodynamic effects of hypericin on lipid peroxidation and antioxidant status in melanoma cells. ( Favier, A; Hadjur, C; Jardon, P; Parat, MO; Richard, MJ, 1996) |
| "Hypericin was taken up by all melanoma cells and partially co-localized to the endoplasmic reticulum, mitochondria, lysosomes and melanosomes, but not the nucleus." | 1.40 | St John's Wort (Hypericum perforatum L.) photomedicine: hypericin-photodynamic therapy induces metastatic melanoma cell death. ( Davids, LM; Kleemann, B; Lang, D; Loos, B; Scriba, TJ, 2014) |
| "Melanoma is the main cause of death in skin cancers." | 1.38 | Depigmentation in melanomas increases the efficacy of hypericin-mediated photodynamic-induced cell death. ( Davids, LM; Sharma, KV, 2012) |
| " This would result in toxic melanin precursors (of an indolic and phenolic nature) leaking into the cytoplasm which in turn leads to cell death." | 1.35 | Hypericin phototoxicity induces different modes of cell death in melanoma and human skin cells. ( Davids, LM; Kacerovská, D; Kidson, SH; Kleemann, B; Pizinger, K, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 5 (55.56) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Naidoo, C | 1 |
| Kruger, CA | 1 |
| Abrahamse, H | 1 |
| Biteghe, FAN | 1 |
| Padayachee, E | 1 |
| Davids, LM | 7 |
| Chalomie, NET | 1 |
| Ndong, JC | 1 |
| Barth, S | 1 |
| Kleemann, B | 3 |
| Loos, B | 1 |
| Scriba, TJ | 1 |
| Lang, D | 1 |
| Biteghe, FN | 1 |
| Cooper, S | 1 |
| Kidson, SH | 2 |
| Sharma, KV | 2 |
| Bowers, N | 1 |
| Kacerovská, D | 1 |
| Pizinger, K | 1 |
| Hadjur, C | 1 |
| Richard, MJ | 1 |
| Parat, MO | 1 |
| Jardon, P | 1 |
| Favier, A | 1 |
1 review available for hypericin and Malignant Melanoma
| Article | Year |
|---|---|
Simultaneous Photodiagnosis and Photodynamic Treatment of Metastatic Melanoma.
Topics: Aminolevulinic Acid; Anthracenes; Biopsy, Fine-Needle; Drug Carriers; Early Diagnosis; Humans; Indol | 2019 |
8 other studies available for hypericin and Malignant Melanoma
| Article | Year |
|---|---|
Desensitization of metastatic melanoma cells to therapeutic treatment through repeated exposure to dacarbazine.
Topics: Anthracenes; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; ATP Bi | 2020 |
St John's Wort (Hypericum perforatum L.) photomedicine: hypericin-photodynamic therapy induces metastatic melanoma cell death.
Topics: Anthracenes; Apoptosis; Apoptosis Regulatory Proteins; Cell Line, Tumor; Cell Size; Drug Screening A | 2014 |
A combination of photodynamic therapy and chemotherapy displays a differential cytotoxic effect on human metastatic melanoma cells.
Topics: Anthracenes; Antineoplastic Agents; Cell Line, Tumor; Dacarbazine; Humans; Melanoma; Neoplasm Metast | 2017 |
Melanomas display increased cytoprotection to hypericin-mediated cytotoxicity through the induction of autophagy.
Topics: Anthracenes; Autophagy; Cell Death; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; Huma | 2009 |
Photodynamic therapy-induced killing is enhanced in depigmented metastatic melanoma cells.
Topics: Anthracenes; Cell Line, Tumor; Cell Survival; Humans; Melanoma; Monophenol Monooxygenase; Perylene; | 2011 |
Depigmentation in melanomas increases the efficacy of hypericin-mediated photodynamic-induced cell death.
Topics: Anthracenes; Apoptosis; Cell Line, Tumor; Humans; Melanins; Melanoma; Perylene; Photochemotherapy; P | 2012 |
Hypericin phototoxicity induces different modes of cell death in melanoma and human skin cells.
Topics: Anthracenes; Apoptosis; Caspase 3; Caspase 7; Cell Death; Cell Line, Tumor; Cell Survival; Humans; I | 2008 |
Photodynamic effects of hypericin on lipid peroxidation and antioxidant status in melanoma cells.
Topics: Anthracenes; Humans; Lipid Peroxidation; Melanoma; Perylene; Photochemotherapy; Radiation-Sensitizin | 1996 |