hypericin has been researched along with Fibrosarcoma in 11 studies
Fibrosarcoma: A sarcoma derived from deep fibrous tissue, characterized by bundles of immature proliferating fibroblasts with variable collagen formation, which tends to invade locally and metastasize by the bloodstream. (Stedman, 25th ed)
Excerpt | Relevance | Reference |
---|---|---|
"Histomorphological changes in murine fibrosarcoma after photodynamic therapy (PDT) based on the natural photosensitizer hypericin were evaluated." | 7.74 | Histomorphological changes in murine fibrosarcoma after hypericin-based photodynamic therapy. ( Bobrov, N; Brezáni, P; Cavarga, I; Fedorocko, P; Longauer, F; Mirossay, L; Miskovský, P; Rybárová, S; Stubna, J, 2007) |
"Hypericin, a potent necrosis avid agent, features a peculiar affinity for necrotic tissue." | 7.74 | Exploration of the mechanism underlying the tumor necrosis avidity of hypericin. ( De Witte, PA; Ni, Y; Van de Putte, M, 2008) |
"To study the effect of co-injecting unlabelled hypericin (Hyp) on biodistribution, necrosis uptake and tumour retention of iodine-123 or iodine-131 labelled hypericin ((123/131)I-Hyp), a necrosis avid agent for an anticancer radiotherapy." | 3.80 | Targetability and biodistribution of radioiodinated hypericin: comparison between microdosing and carrier-added preparations. ( Chen, F; Cona, MM; Feng, Y; Li, J; Ni, Y; Oyen, R; Verbruggen, A; Witte, Pd, 2014) |
"Thirty severe combined immunodeficiency (SCID) mice bearing bilateral radiation-induced fibrosarcoma-1 (RIF-1) subcutaneously were divided into group A of SMSDTTS with sequential intravenous injections of combretastatin A4 phosphate (CA4P) and (131)I-iodohypericin ((131)I-Hyp) at a 24 h interval; group B of single targeting control with CA4P and vehicle of (131)I-Hyp; and group C of vehicle control (10 mice per group)." | 3.79 | Sequential systemic administrations of combretastatin A4 Phosphate and radioiodinated hypericin exert synergistic targeted theranostic effects with prolonged survival on SCID mice carrying bifocal tumor xenografts. ( Chen, F; Cona, MM; de Witte, P; Feng, Y; Li, J; Ni, Y; Nuyts, J; Oyen, R; Verbruggen, A; Yu, J; Zhang, G; Zhang, J; Zhou, L, 2013) |
"Histomorphological changes in murine fibrosarcoma after photodynamic therapy (PDT) based on the natural photosensitizer hypericin were evaluated." | 3.74 | Histomorphological changes in murine fibrosarcoma after hypericin-based photodynamic therapy. ( Bobrov, N; Brezáni, P; Cavarga, I; Fedorocko, P; Longauer, F; Mirossay, L; Miskovský, P; Rybárová, S; Stubna, J, 2007) |
"Seven mice bearing intrahepatic radiation-induced fibrosarcoma-1 tumors were intravenously injected with hypericin 1 hour before (n = 3) or 24 hours after (n = 4) intratumoral ethanol injection." | 3.74 | Hypericin as a marker for determination of tissue viability after intratumoral ethanol injection in a murine liver tumor model. ( Chen, F; de Witte, PA; Ni, Y; Van de Putte, M; Wang, H, 2008) |
"Hypericin, a potent necrosis avid agent, features a peculiar affinity for necrotic tissue." | 3.74 | Exploration of the mechanism underlying the tumor necrosis avidity of hypericin. ( De Witte, PA; Ni, Y; Van de Putte, M, 2008) |
" 33% fractionated dose), but the fractionated schedule of hypericin dosing was found to be more efficient than the single dose, measured by survival assay (p < 0." | 1.33 | Photoinduced antitumour effect of hypericin can be enhanced by fractionated dosing. ( Bobrov, N; Brezáni, P; Cavarga, I; Fedorocko, P; Longauer, F; Mirossay, L; Miskovský, P; Rybárova, S; Stubna, J, 2005) |
"Hypericin is a natural photosensitizer produced in plants of the genus Hypericum." | 1.31 | Synergistic effect of photodynamic therapy with hypericin in combination with hyperthermia on loss of clonogenicity of RIF-1 cells. ( Agostinis, P; Chen, B; De Witte, PA; Xu, Y, 2001) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 8 (72.73) | 29.6817 |
2010's | 3 (27.27) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Li, J | 3 |
Cona, MM | 3 |
Chen, F | 3 |
Feng, Y | 2 |
Zhou, L | 1 |
Zhang, G | 1 |
Nuyts, J | 1 |
de Witte, P | 1 |
Zhang, J | 1 |
Yu, J | 1 |
Oyen, R | 2 |
Verbruggen, A | 3 |
Ni, Y | 6 |
Witte, Pd | 1 |
Van de Putte, M | 3 |
Marysael, T | 1 |
Fonge, H | 1 |
Roskams, T | 3 |
Bormans, G | 1 |
de Witte, PA | 6 |
Chen, B | 3 |
Ahmed, B | 1 |
Landuyt, W | 1 |
Gaspar, R | 1 |
Cavarga, I | 3 |
Brezáni, P | 3 |
Fedorocko, P | 3 |
Miskovský, P | 3 |
Bobrov, N | 2 |
Longauer, F | 2 |
Rybárova, S | 2 |
Mirossay, L | 2 |
Stubna, J | 2 |
Wang, H | 1 |
Xu, Y | 2 |
Agostinis, P | 2 |
Cekanová-Figurová, M | 1 |
Solár, P | 1 |
11 other studies available for hypericin and Fibrosarcoma
Article | Year |
---|---|
Sequential systemic administrations of combretastatin A4 Phosphate and radioiodinated hypericin exert synergistic targeted theranostic effects with prolonged survival on SCID mice carrying bifocal tumor xenografts.
Topics: Administration, Intravenous; Animals; Anthracenes; Antineoplastic Agents; Disease Models, Animal; Fi | 2013 |
Targetability and biodistribution of radioiodinated hypericin: comparison between microdosing and carrier-added preparations.
Topics: Animals; Anthracenes; Antineoplastic Agents; Chromatography, High Pressure Liquid; Drug Carriers; Fi | 2014 |
Radiolabeled iodohypericin as tumor necrosis avid tracer: diagnostic and therapeutic potential.
Topics: Animals; Anthracenes; Autoradiography; Female; Fibrosarcoma; Fluorodeoxyglucose F18; Mice; Mice, Inb | 2012 |
Potentiation of photodynamic therapy with hypericin by mitomycin C in the radiation-induced fibrosarcoma-1 mouse tumor model.
Topics: Animals; Anthracenes; Disease Models, Animal; Drug Synergism; Female; Fibrosarcoma; Mice; Mitomycin; | 2003 |
Photoinduced antitumour effect of hypericin can be enhanced by fractionated dosing.
Topics: Animals; Anthracenes; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Drug Administration Sched | 2005 |
Histomorphological changes in murine fibrosarcoma after hypericin-based photodynamic therapy.
Topics: Animals; Anthracenes; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Disease Models, Animal; F | 2007 |
Hypericin as a marker for determination of tissue viability after intratumoral ethanol injection in a murine liver tumor model.
Topics: Analysis of Variance; Animals; Anthracenes; Antineoplastic Agents; Disease Models, Animal; Ethanol; | 2008 |
Exploration of the mechanism underlying the tumor necrosis avidity of hypericin.
Topics: Animals; Anthracenes; Carbocyanines; Female; Fibrosarcoma; Lipoproteins; Mice; Mice, Inbred C3H; Nec | 2008 |
Synergistic effect of photodynamic therapy with hypericin in combination with hyperthermia on loss of clonogenicity of RIF-1 cells.
Topics: Animals; Anthracenes; Apoptosis; Blotting, Western; Cell Death; Combined Modality Therapy; Drug Syne | 2001 |
Photodynamic therapy of murine fibrosarcoma with topical and systemic administration of hypericin.
Topics: Animals; Anthracenes; Antineoplastic Agents, Phytogenic; Fibrosarcoma; Light; Male; Mice; Mice, Inbr | 2001 |
Photodynamic therapy with hypericin induces vascular damage and apoptosis in the RIF-1 mouse tumor model.
Topics: Animals; Anthracenes; Apoptosis; Blood Vessels; Cell Nucleus; Cell Survival; DNA Fragmentation; Dose | 2002 |