Page last updated: 2024-10-28

hypericin and Experimental Neoplasms

hypericin has been researched along with Experimental Neoplasms in 12 studies

Research Excerpts

ExcerptRelevanceReference
"To study the effect of co-injecting unlabelled hypericin (Hyp) on biodistribution, necrosis uptake and tumour retention of iodine-123 or iodine-131 labelled hypericin ((123/131)I-Hyp), a necrosis avid agent for an anticancer radiotherapy."3.80Targetability and biodistribution of radioiodinated hypericin: comparison between microdosing and carrier-added preparations. ( Chen, F; Cona, MM; Feng, Y; Li, J; Ni, Y; Oyen, R; Verbruggen, A; Witte, Pd, 2014)
" Avastin (bevacizumab), a vascular endothelial growth factor (VEGF) specific monoclonal antibody in combination with chemotherapy is offering hope to patients with metastatic colorectal cancer."1.34Hypericin-mediated photodynamic therapy in combination with Avastin (bevacizumab) improves tumor response by downregulating angiogenic proteins. ( Bhuvaneswari, R; Chee, SK; Olivo, M; Yuen, GY, 2007)
"Hypericin is a potent agent in the photodynamic therapy of cancers."1.33Elucidation of the tumoritropic principle of hypericin. ( Agostinis, P; de Witte, PA; Roskams, T; Van de Putte, M; Vandenheede, JR, 2005)
"Hypericin is a potent agent in the photodynamic therapy of cancers and accumulates to a large extent in tumor tissue."1.33The impact of aggregation on the biodistribution of hypericin. ( Bormans, G; De Witte, PA; Roskams, T; Van De Putte, M; Verbruggen, A, 2006)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's9 (75.00)29.6817
2010's3 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cona, MM1
Li, J1
Feng, Y1
Chen, F1
Verbruggen, A2
Witte, Pd1
Oyen, R1
Ni, Y1
Urla, C1
Armeanu-Ebinger, S1
Fuchs, J1
Seitz, G1
Buríková, M1
Bilčík, B1
Máčajová, M1
Výboh, P1
Bizik, J1
Mateašík, A1
Miškovský, P1
Čavarga, I1
Delaey, E2
Zupko, I2
Chen, B3
Derycke, A1
van Laar, F1
De Vos, D1
De Witte, P2
Van de Putte, M2
Roskams, T3
Vandenheede, JR2
Agostinis, P2
de Witte, PA4
Zhou, Q1
Olivo, M2
Lye, KY1
Moore, S1
Sharma, A1
Chowbay, B1
Bormans, G1
Bhuvaneswari, R1
Yuen, GY1
Chee, SK1
Kamuhabwa, AR1
D'Hallewin, MA1
Baert, L1
Xu, Y1
Blank, M1
Mandel, M1
Hazan, S1
Keisari, Y1
Lavie, G1

Trials

1 trial available for hypericin and Experimental Neoplasms

ArticleYear
Enhancing the therapeutic responsiveness of photodynamic therapy with the antiangiogenic agents SU5416 and SU6668 in murine nasopharyngeal carcinoma models.
    Cancer chemotherapy and pharmacology, 2005, Volume: 56, Issue:6

    Topics: Adenocarcinoma; Angiogenesis Inhibitors; Animals; Anthracenes; Antineoplastic Agents; Chemotherapy,

2005

Other Studies

11 other studies available for hypericin and Experimental Neoplasms

ArticleYear
Targetability and biodistribution of radioiodinated hypericin: comparison between microdosing and carrier-added preparations.
    Anti-cancer agents in medicinal chemistry, 2014, Volume: 14, Issue:6

    Topics: Animals; Anthracenes; Antineoplastic Agents; Chromatography, High Pressure Liquid; Drug Carriers; Fi

2014
Successful in vivo tumor visualization using fluorescence laparoscopy in a mouse model of disseminated alveolar rhabdomyosarcoma.
    Surgical endoscopy, 2015, Volume: 29, Issue:5

    Topics: Animals; Anthracenes; Apoptosis; Fluorescence; In Situ Nick-End Labeling; Laparoscopy; Mice; Mice, I

2015
Hypericin fluorescence kinetics in the presence of low density lipoproteins: study on quail CAM assay for topical delivery.
    General physiology and biophysics, 2016, Volume: 35, Issue:4

    Topics: Administration, Topical; Animals; Anthracenes; Biological Assay; Cell Line, Tumor; Chorioallantoic M

2016
Comparison of hexamethylhypericin and tetrabromohypericin to hypericin for their in vivo efficacy as PDT tools.
    International journal of oncology, 2003, Volume: 23, Issue:2

    Topics: Animals; Anthracenes; Antineoplastic Agents; Blood Proteins; Female; Humans; Lymphoma; Mice; Mice, I

2003
Elucidation of the tumoritropic principle of hypericin.
    British journal of cancer, 2005, Apr-25, Volume: 92, Issue:8

    Topics: Animals; Anthracenes; Antineoplastic Agents; Caco-2 Cells; Carbocyanines; Carbon Radioisotopes; Fema

2005
The impact of aggregation on the biodistribution of hypericin.
    International journal of oncology, 2006, Volume: 28, Issue:3

    Topics: Animals; Anthracenes; Cell Line, Tumor; Female; Injections, Intravenous; Liver; Lung; Metabolic Clea

2006
Hypericin-mediated photodynamic therapy in combination with Avastin (bevacizumab) improves tumor response by downregulating angiogenic proteins.
    Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2007, Volume: 6, Issue:12

    Topics: Angiogenic Proteins; Animals; Anthracenes; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized

2007
Photodynamic therapy efficacy and tissue distribution of hypericin in a mouse P388 lymphoma tumor model.
    Cancer letters, 2000, Mar-13, Volume: 150, Issue:1

    Topics: Animals; Anthracenes; Antineoplastic Agents; Disease Models, Animal; Dose-Response Relationship, Dru

2000
In vivo photodynamic activity of hypericin in transitional cell carcinoma bladder tumors.
    International journal of oncology, 2001, Volume: 18, Issue:5

    Topics: Animals; Anthracenes; Antineoplastic Agents; Carcinoma, Transitional Cell; Female; Injections, Intra

2001
Efficacy of antitumoral photodynamic therapy with hypericin: relationship between biodistribution and photodynamic effects in the RIF-1 mouse tumor model.
    International journal of cancer, 2001, Jul-15, Volume: 93, Issue:2

    Topics: Animals; Anthracenes; Antineoplastic Agents; Dermatitis, Phototoxic; Disease Models, Animal; Female;

2001
Anti-cancer activities of hypericin in the dark.
    Photochemistry and photobiology, 2001, Volume: 74, Issue:2

    Topics: Animals; Anthracenes; Antineoplastic Agents; Cell Survival; Darkness; Female; Male; Mice; Mice, Inbr

2001