hypericin has been researched along with Colonic Neoplasms in 22 studies
Colonic Neoplasms: Tumors or cancer of the COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The hypericin and hyperforin effect has been described to understand the signal mechanisms that stimulate or stunt cancer cell sprouting to metastasis on colon adenocarcinoma cells HT-29 and its resistant form HT-29-OxR." | 7.88 | The potential of hypericin and hyperforin for antiadhesion therapy to prevent metastasis of parental and oxaliplatin-resistant human adenocarcinoma cells (HT-29). ( Fedoročko, P; Sačková, V; Šemeláková, M, 2018) |
| "Colon cancer affects 1." | 5.51 | An Electron paramagnetic resonance (EPR) spin labeling study in HT-29 Colon adenocarcinoma cells after Hypericin-mediated photodynamic therapy. ( Kılıç Süloğlu, A; Selmanoğlu, G; Sünnetçioğlu, MM; Yonar, D, 2019) |
| "Hypericin (HY) has found applications in photodynamic diagnostics solely due to its high specificity for tumour cells and tissues." | 5.37 | Lower sensitivity of FHC fetal colon epithelial cells to photodynamic therapy compared to HT-29 colon adenocarcinoma cells despite higher intracellular accumulation of hypericin. ( Fedoročko, P; Hofmanová, J; Hýžďalová, M; Jendželovský, R; Kočí, L; Kovaľ, J; Kozubík, A; Mikeš, J; Vaculová, A, 2011) |
| "Necrosis was the principal mode of cell death despite different PDT doses and the absence of anti-apoptotic Bcl-2 expression, even if the same condition induced caspase-3 activity at similar toxicity in HeLa cells." | 5.34 | Necrosis predominates in the cell death of human colon adenocarcinoma HT-29 cells treated under variable conditions of photodynamic therapy with hypericin. ( Fedorocko, P; Hofmanová, J; Horváth, V; Jamborová, E; Kleban, J; Kozubík, A; Mikes, J; Sacková, V; Vaculová, A, 2007) |
| "Hypericin was concentrated in the perinucleolar cytoplasmic area mainly on one side of the nucleus--the region rich in endoplasmic reticulum and Golgi." | 5.31 | Intracellular localisation of hypericin in human glioblastoma and carcinoma cell lines. ( Hjortland, GO; Iani, V; Ma, LW; Moan, J; Steen, HB; Uzdensky, AB, 2001) |
| " The hypericin and hyperforin effect has been described to understand the signal mechanisms that stimulate or stunt cancer cell sprouting to metastasis on colon adenocarcinoma cells HT-29 and its resistant form HT-29-OxR." | 3.88 | The potential of hypericin and hyperforin for antiadhesion therapy to prevent metastasis of parental and oxaliplatin-resistant human adenocarcinoma cells (HT-29). ( Fedoročko, P; Sačková, V; Šemeláková, M, 2018) |
| "Hypericin has shown anticancer activity against the expansion of several cell types including breast cancer, cervical cancer, colorectal cancer, colon cancer, hepatocellular carcinoma, stomach carcinoma, leukemia, lung cancer, melanoma, and glioblastoma cancer." | 2.82 | Hypericin and its anticancer effects: From mechanism of action to potential therapeutic application. ( Bishayee, A; Choudhary, N; Collignon, TE; Tewari, D, 2022) |
| "Colon cancer affects 1." | 1.51 | An Electron paramagnetic resonance (EPR) spin labeling study in HT-29 Colon adenocarcinoma cells after Hypericin-mediated photodynamic therapy. ( Kılıç Süloğlu, A; Selmanoğlu, G; Sünnetçioğlu, MM; Yonar, D, 2019) |
| "Hypericin (HY) has found applications in photodynamic diagnostics solely due to its high specificity for tumour cells and tissues." | 1.37 | Lower sensitivity of FHC fetal colon epithelial cells to photodynamic therapy compared to HT-29 colon adenocarcinoma cells despite higher intracellular accumulation of hypericin. ( Fedoročko, P; Hofmanová, J; Hýžďalová, M; Jendželovský, R; Kočí, L; Kovaľ, J; Kozubík, A; Mikeš, J; Vaculová, A, 2011) |
| "Necrosis was the principal mode of cell death despite different PDT doses and the absence of anti-apoptotic Bcl-2 expression, even if the same condition induced caspase-3 activity at similar toxicity in HeLa cells." | 1.34 | Necrosis predominates in the cell death of human colon adenocarcinoma HT-29 cells treated under variable conditions of photodynamic therapy with hypericin. ( Fedorocko, P; Hofmanová, J; Horváth, V; Jamborová, E; Kleban, J; Kozubík, A; Mikes, J; Sacková, V; Vaculová, A, 2007) |
| "Hyperforin is considered to be a primary cause of the inductive effect of St." | 1.33 | Functional induction and de-induction of P-glycoprotein by St. John's wort and its ingredients in a human colon adenocarcinoma cell line. ( Koyabu, N; Morimoto, S; Ohtani, H; Sawada, Y; Shoyama, Y; Tian, R, 2005) |
| "Hypericin was concentrated in the perinucleolar cytoplasmic area mainly on one side of the nucleus--the region rich in endoplasmic reticulum and Golgi." | 1.31 | Intracellular localisation of hypericin in human glioblastoma and carcinoma cell lines. ( Hjortland, GO; Iani, V; Ma, LW; Moan, J; Steen, HB; Uzdensky, AB, 2001) |
| " Chronic use of Saint John's wort (SJW) has been shown to lower the bioavailability for a variety of co-administered drugs including indinavir, cyclosporin, and digoxin." | 1.31 | Saint John's wort: an in vitro analysis of P-glycoprotein induction due to extended exposure. ( Greenblatt, DJ; Perloff, MD; Shader, RI; Störmer, E; von Moltke, LL, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 11 (50.00) | 29.6817 |
| 2010's | 10 (45.45) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Choudhary, N | 1 |
| Collignon, TE | 1 |
| Tewari, D | 1 |
| Bishayee, A | 1 |
| Halaburková, A | 1 |
| Jendželovský, R | 7 |
| Kovaľ, J | 4 |
| Herceg, Z | 1 |
| Fedoročko, P | 11 |
| Ghantous, A | 1 |
| Mühleisen, L | 1 |
| Alev, M | 1 |
| Unterweger, H | 1 |
| Subatzus, D | 1 |
| Pöttler, M | 1 |
| Friedrich, RP | 1 |
| Alexiou, C | 1 |
| Janko, C | 1 |
| Šemeláková, M | 3 |
| Sačková, V | 5 |
| Yonar, D | 1 |
| Kılıç Süloğlu, A | 1 |
| Selmanoğlu, G | 1 |
| Sünnetçioğlu, MM | 1 |
| Mikešová, L | 1 |
| Mikeš, J | 8 |
| Gyurászová, K | 1 |
| Culka, L | 1 |
| Vargová, J | 1 |
| Valeková, B | 1 |
| Kleban, J | 2 |
| Horváth, V | 2 |
| Hofmanová, J | 4 |
| Kozubík, A | 4 |
| Koval', J | 2 |
| Uhrinová, I | 1 |
| Kello, M | 3 |
| Kuliková, L | 1 |
| Soucek, K | 1 |
| Procházková, J | 1 |
| Hýžďalová, M | 1 |
| Kočí, L | 1 |
| Vaculová, A | 2 |
| Sanovic, R | 1 |
| Verwanger, T | 1 |
| Hartl, A | 1 |
| Krammer, B | 1 |
| Ali, SM | 1 |
| Olivo, M | 1 |
| Siboni, G | 2 |
| Weitman, H | 2 |
| Freeman, D | 1 |
| Mazur, Y | 1 |
| Malik, Z | 2 |
| Ehrenberg, B | 2 |
| Amit-Patito, I | 1 |
| Weizman, E | 1 |
| Waintraub-Porat, M | 1 |
| Tian, R | 1 |
| Koyabu, N | 1 |
| Morimoto, S | 1 |
| Shoyama, Y | 1 |
| Ohtani, H | 1 |
| Sawada, Y | 1 |
| Saczko, J | 1 |
| Kulbacka, J | 1 |
| Chwilkowsa, A | 1 |
| Pola, A | 1 |
| Lugowski, M | 1 |
| Marcinkowska, A | 1 |
| Malarska, A | 1 |
| Banas, T | 1 |
| Jamborová, E | 1 |
| Uzdensky, AB | 1 |
| Ma, LW | 1 |
| Iani, V | 1 |
| Hjortland, GO | 1 |
| Steen, HB | 1 |
| Moan, J | 1 |
| Perloff, MD | 1 |
| von Moltke, LL | 1 |
| Störmer, E | 1 |
| Shader, RI | 1 |
| Greenblatt, DJ | 1 |
1 review available for hypericin and Colonic Neoplasms
| Article | Year |
|---|---|
Hypericin and its anticancer effects: From mechanism of action to potential therapeutic application.
Topics: Anthracenes; Antineoplastic Agents; Colonic Neoplasms; Humans; Perylene | 2022 |
21 other studies available for hypericin and Colonic Neoplasms
| Article | Year |
|---|---|
Histone deacetylase inhibitors potentiate photodynamic therapy in colon cancer cells marked by chromatin-mediated epigenetic regulation of
Topics: Anthracenes; Antineoplastic Agents; Cell Line, Tumor; Chromatin; Colonic Neoplasms; Cyclin-Dependent | 2017 |
Analysis of Hypericin-Mediated Effects and Implications for Targeted Photodynamic Therapy.
Topics: Administration, Intravenous; Anthracenes; Cell Death; Cell Proliferation; Colonic Neoplasms; Drug De | 2017 |
The potential of hypericin and hyperforin for antiadhesion therapy to prevent metastasis of parental and oxaliplatin-resistant human adenocarcinoma cells (HT-29).
Topics: Adenocarcinoma; Anthracenes; Antineoplastic Combined Chemotherapy Protocols; Cell Adhesion; Cell Mov | 2018 |
An Electron paramagnetic resonance (EPR) spin labeling study in HT-29 Colon adenocarcinoma cells after Hypericin-mediated photodynamic therapy.
Topics: Adenocarcinoma; Anthracenes; Cell Membrane; Colonic Neoplasms; Computer Simulation; Cyclic N-Oxides; | 2019 |
Conjunction of glutathione level, NAD(P)H/FAD redox status and hypericin content as a potential factor affecting colon cancer cell resistance to photodynamic therapy with hypericin.
Topics: 3-Hydroxysteroid Dehydrogenases; Anthracenes; Cell Line, Tumor; Colonic Neoplasms; Drug Resistance, | 2013 |
Drug membrane transporters and CYP3A4 are affected by hypericin, hyperforin or aristoforin in colon adenocarcinoma cells.
Topics: Adenocarcinoma; Anthracenes; Blotting, Western; Cell Line, Tumor; Colonic Neoplasms; Cytochrome P-45 | 2016 |
Mechanisms involved in the cell cycle and apoptosis of HT-29 cells pre-treated with MK-886 prior to photodynamic therapy with hypericin.
Topics: Anthracenes; Apoptosis; Cell Cycle; Colonic Neoplasms; Drug Synergism; HT29 Cells; Humans; Indoles; | 2008 |
The role of p53 in the efficiency of photodynamic therapy with hypericin and subsequent long-term survival of colon cancer cells.
Topics: Anthracenes; Caspase 3; Cell Cycle; Cell Survival; Colonic Neoplasms; Colony-Forming Units Assay; En | 2009 |
Drug efflux transporters, MRP1 and BCRP, affect the outcome of hypericin-mediated photodynamic therapy in HT-29 adenocarcinoma cells.
Topics: Adenocarcinoma; Anthracenes; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Ca | 2009 |
PUFAs enhance oxidative stress and apoptosis in tumour cells exposed to hypericin-mediated PDT.
Topics: Anthracenes; Antineoplastic Agents; Apoptosis; Arachidonic Acid; Cell Line, Tumor; Colonic Neoplasms | 2010 |
Lower sensitivity of FHC fetal colon epithelial cells to photodynamic therapy compared to HT-29 colon adenocarcinoma cells despite higher intracellular accumulation of hypericin.
Topics: Adenocarcinoma; Anthracenes; Cell Line; Colon; Colonic Neoplasms; Epithelial Cells; Fetus; Humans; M | 2011 |
Low dose hypericin-PDT induces complete tumor regression in BALB/c mice bearing CT26 colon carcinoma.
Topics: Animals; Anthracenes; Cell Line, Tumor; Colonic Neoplasms; Dose-Response Relationship, Drug; Mice; M | 2011 |
The pro-apoptotic and anti-invasive effects of hypericin-mediated photodynamic therapy are enhanced by hyperforin or aristoforin in HT-29 colon adenocarcinoma cells.
Topics: Adenocarcinoma; Anthracenes; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Cycle Checkpoints; Ce | 2012 |
Bio-distribution and subcellular localization of Hypericin and its role in PDT induced apoptosis in cancer cells.
Topics: Anthracenes; Antineoplastic Agents; Apoptosis; Colonic Neoplasms; Cytochrome c Group; Humans; Intrac | 2002 |
The correlation between hydrophilicity of hypericins and helianthrone: internalization mechanisms, subcellular distribution and photodynamic action in colon carcinoma cells.
Topics: Animals; Anthracenes; Colonic Neoplasms; Endocytosis; Flow Cytometry; Mice; Perylene; Photochemother | 2002 |
Specificity of photosensitizer accumulation in undifferentiated versus differentiated colon carcinoma cells.
Topics: Animals; Anthracenes; Butyrates; Carcinoma; Cell Cycle; Cell Differentiation; Colonic Neoplasms; Mic | 2003 |
Functional induction and de-induction of P-glycoprotein by St. John's wort and its ingredients in a human colon adenocarcinoma cell line.
Topics: Adenocarcinoma; Animals; Anthracenes; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biolo | 2005 |
Cytosolic superoxide dismutase activity after photodynamic therapy, intracellular distribution of Photofrin II and hypericin, and P-glycoprotein localization in human colon adenocarcinoma.
Topics: Anthracenes; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Colonic Neop | 2007 |
Necrosis predominates in the cell death of human colon adenocarcinoma HT-29 cells treated under variable conditions of photodynamic therapy with hypericin.
Topics: Adenocarcinoma; Anthracenes; Caspase 3; Cell Cycle; Cell Proliferation; Colonic Neoplasms; Dose-Resp | 2007 |
Intracellular localisation of hypericin in human glioblastoma and carcinoma cell lines.
Topics: Adenocarcinoma; Anthracenes; Carcinoma in Situ; Colonic Neoplasms; Female; Glioblastoma; Humans; Per | 2001 |
Saint John's wort: an in vitro analysis of P-glycoprotein induction due to extended exposure.
Topics: Adenocarcinoma; Anthracenes; Antidepressive Agents; ATP Binding Cassette Transporter, Subfamily B, M | 2001 |