Page last updated: 2024-10-28

hypericin and Carcinoma

hypericin has been researched along with Carcinoma in 8 studies

Carcinoma: A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for cancer.

Research Excerpts

ExcerptRelevanceReference
"Hypericin is a bright red fluorescent compound that can be used in urological medicine as a photodiagnostic to detect non-muscle-invasive bladder cancer lesions."7.77Human serum albumin as key mediator of the differential accumulation of hypericin in normal urothelial cell spheroids versus urothelial cell carcinoma spheroids. ( de Witte, PA; Lerut, E; Roelants, M; Van Cleynenbreugel, B; Van Poppel, H, 2011)
"Photodynamic diagnosis (PDD) using hypericin (HY), a natural photosensitizer, detects bladder cancer significantly better than white light endoscopy."7.74Effects of N-methyl pyrrolidone on the uptake of hypericin in human bladder carcinoma and co-staining with DAPI investigated by confocal microscopy. ( Fu, CY; Kho, KW; Olivo, M; Saw, CL; Sia Heng, PW; Soo, KC; Wohland, T, 2007)
"Photosensitization of HEC1-B cells with a low concentration of hypericin and doses of light below 10 J/cm(2) caused cell death (apoptosis occurred mainly at doses between 2 and 5 J/cm(2), whereas necrosis prevailed above 6 J/cm(2))."7.71Molecular aspects of photodynamic therapy: low energy pre-sensitization of hypericin-loaded human endometrial carcinoma cells enhances photo-tolerance, alters gene expression and affects the cell cycle. ( Coppola, E; Palumbo, G; Quarto, M; Varriale, L; Veneziani, BM, 2002)
"In order to explore the combined effects of gene therapy and hypericin (Hy) on tumor cells, hypoxia-inducible factor 1 alpha (HIF-1α) small interfering ribonucleic acid (siRNA) was transfected into the hypoxic human nasopharyngeal carcinoma (CNE2) cells using Hy-encapsulated nanocomplexes (Hy-HPP NPs) as a carrier which would achieve dual targeting to the tumor necrosis area."3.83Co-delivery of siRNA and hypericin into cancer cells by hyaluronic acid modified PLGA-PEI nanoparticles. ( Li, Y; Ouahab, A; Shen, Y; Wang, B; Zhang, J, 2016)
" Therefore, we preloaded microplates with hypericin, Foscan, PVP-hypericin, or aluminum (III) phthalocyanine tetrasulfonate chloride (AlPCS4) for 24 hours and measured the PS distribution after addition of A431 human carcinoma cells: following another 24 hours up to 68% of hypericin were detected in the cell fraction."3.79Photosensitizer adhered to cell culture microplates induces phototoxicity in carcinoma cells. ( Kiesslich, T; Krammer, B; Plaetzer, K; Ziegler, V, 2013)
"Hypericin is a bright red fluorescent compound that can be used in urological medicine as a photodiagnostic to detect non-muscle-invasive bladder cancer lesions."3.77Human serum albumin as key mediator of the differential accumulation of hypericin in normal urothelial cell spheroids versus urothelial cell carcinoma spheroids. ( de Witte, PA; Lerut, E; Roelants, M; Van Cleynenbreugel, B; Van Poppel, H, 2011)
"Photodynamic diagnosis (PDD) using hypericin (HY), a natural photosensitizer, detects bladder cancer significantly better than white light endoscopy."3.74Effects of N-methyl pyrrolidone on the uptake of hypericin in human bladder carcinoma and co-staining with DAPI investigated by confocal microscopy. ( Fu, CY; Kho, KW; Olivo, M; Saw, CL; Sia Heng, PW; Soo, KC; Wohland, T, 2007)
"Photosensitization of HEC1-B cells with a low concentration of hypericin and doses of light below 10 J/cm(2) caused cell death (apoptosis occurred mainly at doses between 2 and 5 J/cm(2), whereas necrosis prevailed above 6 J/cm(2))."3.71Molecular aspects of photodynamic therapy: low energy pre-sensitization of hypericin-loaded human endometrial carcinoma cells enhances photo-tolerance, alters gene expression and affects the cell cycle. ( Coppola, E; Palumbo, G; Quarto, M; Varriale, L; Veneziani, BM, 2002)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (50.00)29.6817
2010's4 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ziegler, V1
Kiesslich, T1
Krammer, B1
Plaetzer, K1
Zhu, M1
Lin, XA1
Zha, XM1
Zhou, WB1
Xia, TS1
Wang, S1
Li, Y1
Zhang, J1
Wang, B1
Shen, Y1
Ouahab, A1
Roelants, M1
Van Cleynenbreugel, B1
Lerut, E1
Van Poppel, H1
de Witte, PA1
Siboni, G1
Amit-Patito, I1
Weizman, E1
Waintraub-Porat, M1
Weitman, H1
Ehrenberg, B1
Malik, Z1
Du, HY1
Olivo, M2
Chen, YJ1
Yip, G1
Tan, PH1
Matsumoto, K1
Tsujimoto, M1
Bay, BH1
Saw, CL1
Wohland, T1
Fu, CY1
Kho, KW1
Soo, KC1
Sia Heng, PW1
Varriale, L1
Coppola, E1
Quarto, M1
Veneziani, BM1
Palumbo, G1

Other Studies

8 other studies available for hypericin and Carcinoma

ArticleYear
Photosensitizer adhered to cell culture microplates induces phototoxicity in carcinoma cells.
    BioMed research international, 2013, Volume: 2013

    Topics: Anthracenes; Carcinoma; Cell Adhesion; Cell Culture Techniques; Cell Line, Tumor; Cell Membrane; Cul

2013
Evaluation of the therapeutic efficacy of sequential therapy involving percutaneous microwave ablation in combination with 131I-hypericin using the VX2 rabbit breast solid tumor model.
    PloS one, 2015, Volume: 10, Issue:3

    Topics: Ablation Techniques; Animals; Anthracenes; Antineoplastic Agents; Carcinoma; Drug Evaluation, Precli

2015
Co-delivery of siRNA and hypericin into cancer cells by hyaluronic acid modified PLGA-PEI nanoparticles.
    Drug development and industrial pharmacy, 2016, Volume: 42, Issue:5

    Topics: Anthracenes; Carcinoma; Cell Line, Tumor; Humans; Hyaluronic Acid; Hypoxia-Inducible Factor 1, alpha

2016
Human serum albumin as key mediator of the differential accumulation of hypericin in normal urothelial cell spheroids versus urothelial cell carcinoma spheroids.
    Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2011, Volume: 10, Issue:1

    Topics: Anthracenes; Carcinoma; Cells, Cultured; Humans; Perylene; Photochemotherapy; Photosensitizing Agent

2011
Specificity of photosensitizer accumulation in undifferentiated versus differentiated colon carcinoma cells.
    Cancer letters, 2003, Jun-30, Volume: 196, Issue:1

    Topics: Animals; Anthracenes; Butyrates; Carcinoma; Cell Cycle; Cell Differentiation; Colonic Neoplasms; Mic

2003
Expression of Y-Box binding protein-1 following hypericin-mediated photodynamic therapy in well-differentiated nasopharyngeal cancer in vivo.
    International journal of molecular medicine, 2005, Volume: 16, Issue:5

    Topics: Animals; Anthracenes; Antineoplastic Agents; Carcinoma; Humans; Male; Mice; Mice, Inbred BALB C; Nas

2005
Effects of N-methyl pyrrolidone on the uptake of hypericin in human bladder carcinoma and co-staining with DAPI investigated by confocal microscopy.
    Technology in cancer research & treatment, 2007, Volume: 6, Issue:5

    Topics: Anthracenes; Antineoplastic Agents; Biological Availability; Carcinoma; Diagnostic Imaging; Dose-Res

2007
Molecular aspects of photodynamic therapy: low energy pre-sensitization of hypericin-loaded human endometrial carcinoma cells enhances photo-tolerance, alters gene expression and affects the cell cycle.
    FEBS letters, 2002, Feb-13, Volume: 512, Issue:1-3

    Topics: Anthracenes; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Biological Transport; Carcinoma;

2002