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hypericin and Breast Cancer

hypericin has been researched along with Breast Cancer in 16 studies

Research Excerpts

ExcerptRelevanceReference
"To investigate the effects of hypericin which is obtained from the plant Hypericum perforatum on the expression and the regulation of ADAMTS8 and ADAMTS9 genes in MCF7 breast cancer cells and on the viability of these cells."7.79Effect of hypericin on the ADAMTS-9 and ADAMTS-8 gene expression in MCF7 breast cancer cells. ( Acar, M; Demircan, K; Gunduz, E; Gunduz, M; Ocak, Z; Ozlü, T; Uyeturk, U, 2013)
"Breast cancer is the most relevant type of cancer and the second cause of cancer- related deaths among women in general."5.56Selective Photodynamic Effects on Breast Cancer Cells Provided by p123 Pluronic®- Based Nanoparticles Modulating Hypericin Delivery. ( Caetano, W; César, GB; Consolaro, MEL; Damke, E; Damke, GMZF; Gonçalves, RS; Hioka, N; Kimura, E; Montanha, MC; Souza, RP, 2020)
"Hypericin (HY) is a naturally-occurring photosensitizer synthesized by plants of the genus Hypericum."5.51Breast cancer resistance protein is the enemy of hypericin accumulation and toxicity of hypericin-mediated photodynamic therapy. ( Fedoročko, P; Jendželovská, Z; Jendželovský, R; Kuchárová, B, 2019)
"Photoactivated hypericin increased production of reactive oxygen species in human breast adenocarcinoma MCF-7 as well as in MDA-MB-231 cells 1h after photodynamic therapy."3.85Photoactivated hypericin increases the expression of SOD-2 and makes MCF-7 cells resistant to photodynamic therapy. ( Fecková, B; Ilkovičová, L; Kello, M; Kimáková, P; Sačková, V; Solár, P; Solárová, Z, 2017)
"To investigate the effects of hypericin which is obtained from the plant Hypericum perforatum on the expression and the regulation of ADAMTS8 and ADAMTS9 genes in MCF7 breast cancer cells and on the viability of these cells."3.79Effect of hypericin on the ADAMTS-9 and ADAMTS-8 gene expression in MCF7 breast cancer cells. ( Acar, M; Demircan, K; Gunduz, E; Gunduz, M; Ocak, Z; Ozlü, T; Uyeturk, U, 2013)
"The tumoricidal properties of photodynamic therapy (PDT) with hypericin (HY) were evaluated in a highly metastatic adenocarcinoma (DA3Hi) and anaplastic squamous cell carcinoma (SQ2) tumors in vivo."3.70Effects of photodynamic therapy with hypericin in mice bearing highly invasive solid tumors. ( Blank, M; Keisari, Y; Lavie, G; Mandel, M, 2000)
"Breast cancer is the most relevant type of cancer and the second cause of cancer- related deaths among women in general."1.56Selective Photodynamic Effects on Breast Cancer Cells Provided by p123 Pluronic®- Based Nanoparticles Modulating Hypericin Delivery. ( Caetano, W; César, GB; Consolaro, MEL; Damke, E; Damke, GMZF; Gonçalves, RS; Hioka, N; Kimura, E; Montanha, MC; Souza, RP, 2020)
"Hypericin (HY) is a naturally-occurring photosensitizer synthesized by plants of the genus Hypericum."1.51Breast cancer resistance protein is the enemy of hypericin accumulation and toxicity of hypericin-mediated photodynamic therapy. ( Fedoročko, P; Jendželovská, Z; Jendželovský, R; Kuchárová, B, 2019)
"Breast cancer is the major cause of death from cancer among women around the world."1.48Hypericin Induces Apoptosis in MDA-MB-175-VII Cells in Lower Dose Compared to MDA-MB-231. ( Abbasi Gamasaee, N; Aryan, H; Ghiasvand, S; Jangholi, E; Javidi, MA; Radmansouri, M; Shahriari, F; Zare Marzouni, H, 2018)
"Bladder and breast cancer cells and their Pgp-overexpressing MDR subclones (MGHU1, MGHU1/R, MCF-7, MCF-7/R) were given hypericin/MTZ combinations, with/without blue-light illumination."1.34Photochemical internalisation of chemotherapy potentiates killing of multidrug-resistant breast and bladder cancer cells. ( Adigbli, DK; Farooqui, N; Loizidou, M; Macrobert, AJ; Risley, P; Sousi, E; Taylor, I; Wilson, DG, 2007)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (6.25)18.2507
2000's3 (18.75)29.6817
2010's10 (62.50)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Zhou, X1
Xu, X1
Hu, Q1
Wu, Y1
Yu, F1
He, C1
Qian, Y1
Han, Y1
Tang, J1
Hu, H1
R Mokoena, D1
P George, B1
Abrahamse, H1
You, MK1
Kim, HJ1
Kook, JH1
Kim, HA1
Abbasi Gamasaee, N1
Radmansouri, M1
Ghiasvand, S1
Shahriari, F1
Zare Marzouni, H1
Aryan, H1
Jangholi, E1
Javidi, MA1
Damke, GMZF1
Souza, RP1
Montanha, MC1
Damke, E1
Gonçalves, RS1
César, GB1
Kimura, E1
Caetano, W1
Hioka, N1
Consolaro, MEL1
Jendželovský, R1
Jendželovská, Z1
Kuchárová, B1
Fedoročko, P3
Ocak, Z1
Acar, M1
Gunduz, E1
Gunduz, M1
Demircan, K1
Uyeturk, U1
Ozlü, T1
Kimáková, P1
Solár, P3
Fecková, B1
Sačková, V1
Solárová, Z2
Ilkovičová, L1
Kello, M1
Theodossiou, TA1
Olsen, CE1
Jonsson, M1
Kubin, A1
Hothersall, JS1
Berg, K1
Ferenc, P2
Kleban, J1
Mikes, J2
Koval', J1
Hrčková, G1
Fulton, BL1
Song, S1
Xiong, C1
Zhou, M1
Lu, W1
Huang, Q1
Ku, G1
Zhao, J1
Flores, LG1
Ni, Y1
Li, C1
Blank, M2
Lavie, G2
Mandel, M2
Hazan, S1
Orenstein, A1
Meruelo, D1
Keisari, Y2
Adigbli, DK1
Wilson, DG1
Farooqui, N1
Sousi, E1
Risley, P1
Taylor, I1
Macrobert, AJ1
Loizidou, M1
Miskovsky, P1
Sureau, F1
Chinsky, L1
Turpin, PY1

Reviews

1 review available for hypericin and Breast Cancer

ArticleYear
Enhancing Breast Cancer Treatment Using a Combination of Cannabidiol and Gold Nanoparticles for Photodynamic Therapy.
    International journal of molecular sciences, 2019, Sep-26, Volume: 20, Issue:19

    Topics: Animals; Anthracenes; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cannabidiol; Combined Mod

2019

Other Studies

15 other studies available for hypericin and Breast Cancer

ArticleYear
Novel manganese and polyester dendrimer-based theranostic nanoparticles for MRI and breast cancer therapy.
    Journal of materials chemistry. B, 2023, 01-18, Volume: 11, Issue:3

    Topics: Breast Neoplasms; Dendrimers; Female; Humans; Magnetic Resonance Imaging; Manganese; Nanoparticles;

2023
St. John's Wort Regulates Proliferation and Apoptosis in MCF-7 Human Breast Cancer Cells by Inhibiting AMPK/mTOR and Activating the Mitochondrial Pathway.
    International journal of molecular sciences, 2018, Mar-23, Volume: 19, Issue:4

    Topics: AMP-Activated Protein Kinases; Anthracenes; Breast Neoplasms; Cell Line, Tumor; Humans; Hypericum; M

2018
Hypericin Induces Apoptosis in MDA-MB-175-VII Cells in Lower Dose Compared to MDA-MB-231.
    Archives of Iranian medicine, 2018, 09-01, Volume: 21, Issue:9

    Topics: Anthracenes; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferatio

2018
Selective Photodynamic Effects on Breast Cancer Cells Provided by p123 Pluronic®- Based Nanoparticles Modulating Hypericin Delivery.
    Anti-cancer agents in medicinal chemistry, 2020, Volume: 20, Issue:11

    Topics: Anthracenes; Antineoplastic Agents; Breast Neoplasms; Cell Death; Cell Proliferation; Cell Survival;

2020
Breast cancer resistance protein is the enemy of hypericin accumulation and toxicity of hypericin-mediated photodynamic therapy.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 109

    Topics: Anthracenes; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Breast

2019
Effect of hypericin on the ADAMTS-9 and ADAMTS-8 gene expression in MCF7 breast cancer cells.
    European review for medical and pharmacological sciences, 2013, Volume: 17, Issue:9

    Topics: ADAM Proteins; ADAMTS Proteins; ADAMTS9 Protein; Anthracenes; Breast Neoplasms; Cell Line, Tumor; Ce

2013
Photoactivated hypericin increases the expression of SOD-2 and makes MCF-7 cells resistant to photodynamic therapy.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 85

    Topics: 2-Methoxyestradiol; Adenocarcinoma; Anthracenes; Breast Neoplasms; Cell Line, Tumor; Estradiol; Fema

2017
The diverse roles of glutathione-associated cell resistance against hypericin photodynamic therapy.
    Redox biology, 2017, Volume: 12

    Topics: Anthracenes; Breast Neoplasms; Buthionine Sulfoximine; Carmustine; Cell Line, Tumor; Drug Resistance

2017
Down-regulation of Bcl-2 and Akt induced by combination of photoactivated hypericin and genistein in human breast cancer cells.
    Journal of photochemistry and photobiology. B, Biology, 2010, Jan-21, Volume: 98, Issue:1

    Topics: Anthracenes; bcl-2-Associated X Protein; Breast Neoplasms; Caspase 7; Cell Division; Cell Line, Tumo

2010
Photoactivated hypericin induces downregulation of HER2 gene expression.
    Radiation research, 2011, Volume: 175, Issue:1

    Topics: Anthracenes; Breast Neoplasms; Cell Line, Tumor; Down-Regulation; Female; Genes, erbB-2; Humans; Per

2011
Small-animal PET of tumor damage induced by photothermal ablation with 64Cu-bis-DOTA-hypericin.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2011, Volume: 52, Issue:5

    Topics: Ablation Techniques; Animals; Anthracenes; Biological Transport; Breast Neoplasms; Cell Line, Tumor;

2011
Antimetastatic activity of the photodynamic agent hypericin in the dark.
    International journal of cancer, 2004, Sep-10, Volume: 111, Issue:4

    Topics: Animals; Anthracenes; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Squamous Cell; Disease Mod

2004
Photochemical internalisation of chemotherapy potentiates killing of multidrug-resistant breast and bladder cancer cells.
    British journal of cancer, 2007, Aug-20, Volume: 97, Issue:4

    Topics: Absorption; Anthracenes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Deat

2007
Subcellular distribution of hypericin in human cancer cells.
    Photochemistry and photobiology, 1995, Volume: 62, Issue:3

    Topics: Anthracenes; Antiviral Agents; Breast Neoplasms; Fluorometry; Humans; Perylene; Protein Kinase C; Sp

1995
Effects of photodynamic therapy with hypericin in mice bearing highly invasive solid tumors.
    Oncology research, 2000, Volume: 12, Issue:9-10

    Topics: Adenocarcinoma; Animals; Anthracenes; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Squamous C

2000