hypericin has been researched along with Adenocarcinoma in 17 studies
Adenocarcinoma: A malignant epithelial tumor with a glandular organization.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The hypericin and hyperforin effect has been described to understand the signal mechanisms that stimulate or stunt cancer cell sprouting to metastasis on colon adenocarcinoma cells HT-29 and its resistant form HT-29-OxR." | 7.88 | The potential of hypericin and hyperforin for antiadhesion therapy to prevent metastasis of parental and oxaliplatin-resistant human adenocarcinoma cells (HT-29). ( Fedoročko, P; Sačková, V; Šemeláková, M, 2018) |
| " In this study, the combined effect of hypericin (the photodynamically-active pigment from Hypericum perforatum) and selective farnesyltransferase inhibitor manumycin (manumycin A; the selective farnesyltransferase inhibitor from Streptomyces parvulus) on HT-29 adenocarcinoma cells was examined." | 7.77 | Enhanced antiproliferative and apoptotic response of HT-29 adenocarcinoma cells to combination of photoactivated hypericin and farnesyltransferase inhibitor manumycin A. ( Fedoročko, P; Kello, M; Kuliková, L; Sačková, V; Uhrinová, I, 2011) |
| "Colon cancer affects 1." | 5.51 | An Electron paramagnetic resonance (EPR) spin labeling study in HT-29 Colon adenocarcinoma cells after Hypericin-mediated photodynamic therapy. ( Kılıç Süloğlu, A; Selmanoğlu, G; Sünnetçioğlu, MM; Yonar, D, 2019) |
| "Hypericin (HY) has found applications in photodynamic diagnostics solely due to its high specificity for tumour cells and tissues." | 5.37 | Lower sensitivity of FHC fetal colon epithelial cells to photodynamic therapy compared to HT-29 colon adenocarcinoma cells despite higher intracellular accumulation of hypericin. ( Fedoročko, P; Hofmanová, J; Hýžďalová, M; Jendželovský, R; Kočí, L; Kovaľ, J; Kozubík, A; Mikeš, J; Vaculová, A, 2011) |
| "Necrosis was the principal mode of cell death despite different PDT doses and the absence of anti-apoptotic Bcl-2 expression, even if the same condition induced caspase-3 activity at similar toxicity in HeLa cells." | 5.34 | Necrosis predominates in the cell death of human colon adenocarcinoma HT-29 cells treated under variable conditions of photodynamic therapy with hypericin. ( Fedorocko, P; Hofmanová, J; Horváth, V; Jamborová, E; Kleban, J; Kozubík, A; Mikes, J; Sacková, V; Vaculová, A, 2007) |
| "Hypericin was concentrated in the perinucleolar cytoplasmic area mainly on one side of the nucleus--the region rich in endoplasmic reticulum and Golgi." | 5.31 | Intracellular localisation of hypericin in human glioblastoma and carcinoma cell lines. ( Hjortland, GO; Iani, V; Ma, LW; Moan, J; Steen, HB; Uzdensky, AB, 2001) |
| " The hypericin and hyperforin effect has been described to understand the signal mechanisms that stimulate or stunt cancer cell sprouting to metastasis on colon adenocarcinoma cells HT-29 and its resistant form HT-29-OxR." | 3.88 | The potential of hypericin and hyperforin for antiadhesion therapy to prevent metastasis of parental and oxaliplatin-resistant human adenocarcinoma cells (HT-29). ( Fedoročko, P; Sačková, V; Šemeláková, M, 2018) |
| "Photoactivated hypericin increased production of reactive oxygen species in human breast adenocarcinoma MCF-7 as well as in MDA-MB-231 cells 1h after photodynamic therapy." | 3.85 | Photoactivated hypericin increases the expression of SOD-2 and makes MCF-7 cells resistant to photodynamic therapy. ( Fecková, B; Ilkovičová, L; Kello, M; Kimáková, P; Sačková, V; Solár, P; Solárová, Z, 2017) |
| " In this study, the combined effect of hypericin (the photodynamically-active pigment from Hypericum perforatum) and selective farnesyltransferase inhibitor manumycin (manumycin A; the selective farnesyltransferase inhibitor from Streptomyces parvulus) on HT-29 adenocarcinoma cells was examined." | 3.77 | Enhanced antiproliferative and apoptotic response of HT-29 adenocarcinoma cells to combination of photoactivated hypericin and farnesyltransferase inhibitor manumycin A. ( Fedoročko, P; Kello, M; Kuliková, L; Sačková, V; Uhrinová, I, 2011) |
| "We have investigated the photoactivating effect of hypericin on two cancer cell lines: PC-3, a prostatic adenocarcinoma non-responsive to androgen therapy and LNCaP, a lymphonodal metastasis of prostate carcinoma responsive to androgen therapy." | 3.70 | Hypericin photosensitization of tumor and metastatic cell lines of human prostate. ( Colasanti, A; Kisslinger, A; Liuzzi, R; Quarto, M; Riccio, P; Roberti, G; Tramontano, D; Villani, F, 2000) |
| "The tumoricidal properties of photodynamic therapy (PDT) with hypericin (HY) were evaluated in a highly metastatic adenocarcinoma (DA3Hi) and anaplastic squamous cell carcinoma (SQ2) tumors in vivo." | 3.70 | Effects of photodynamic therapy with hypericin in mice bearing highly invasive solid tumors. ( Blank, M; Keisari, Y; Lavie, G; Mandel, M, 2000) |
| "Colon cancer affects 1." | 1.51 | An Electron paramagnetic resonance (EPR) spin labeling study in HT-29 Colon adenocarcinoma cells after Hypericin-mediated photodynamic therapy. ( Kılıç Süloğlu, A; Selmanoğlu, G; Sünnetçioğlu, MM; Yonar, D, 2019) |
| "Hypericin (HY) has found applications in photodynamic diagnostics solely due to its high specificity for tumour cells and tissues." | 1.37 | Lower sensitivity of FHC fetal colon epithelial cells to photodynamic therapy compared to HT-29 colon adenocarcinoma cells despite higher intracellular accumulation of hypericin. ( Fedoročko, P; Hofmanová, J; Hýžďalová, M; Jendželovský, R; Kočí, L; Kovaľ, J; Kozubík, A; Mikeš, J; Vaculová, A, 2011) |
| "Necrosis was the principal mode of cell death despite different PDT doses and the absence of anti-apoptotic Bcl-2 expression, even if the same condition induced caspase-3 activity at similar toxicity in HeLa cells." | 1.34 | Necrosis predominates in the cell death of human colon adenocarcinoma HT-29 cells treated under variable conditions of photodynamic therapy with hypericin. ( Fedorocko, P; Hofmanová, J; Horváth, V; Jamborová, E; Kleban, J; Kozubík, A; Mikes, J; Sacková, V; Vaculová, A, 2007) |
| "Hyperforin is considered to be a primary cause of the inductive effect of St." | 1.33 | Functional induction and de-induction of P-glycoprotein by St. John's wort and its ingredients in a human colon adenocarcinoma cell line. ( Koyabu, N; Morimoto, S; Ohtani, H; Sawada, Y; Shoyama, Y; Tian, R, 2005) |
| "Hypericin is a very promising new photosensitizer for innovative photodynamic therapy of esophageal cancer." | 1.32 | Hypericin activated by an incoherent light source has photodynamic effects on esophageal cancer cells. ( Höpfner, M; Kashtan, H; Lenz, M; Maaser, K; Riecken, EO; Scherübl, H; Sutter, AP; Theiss, A; von Lampe, B; Zeitz, M, 2003) |
| "Hypericin was concentrated in the perinucleolar cytoplasmic area mainly on one side of the nucleus--the region rich in endoplasmic reticulum and Golgi." | 1.31 | Intracellular localisation of hypericin in human glioblastoma and carcinoma cell lines. ( Hjortland, GO; Iani, V; Ma, LW; Moan, J; Steen, HB; Uzdensky, AB, 2001) |
| " Chronic use of Saint John's wort (SJW) has been shown to lower the bioavailability for a variety of co-administered drugs including indinavir, cyclosporin, and digoxin." | 1.31 | Saint John's wort: an in vitro analysis of P-glycoprotein induction due to extended exposure. ( Greenblatt, DJ; Perloff, MD; Shader, RI; Störmer, E; von Moltke, LL, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (52.94) | 29.6817 |
| 2010's | 8 (47.06) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Šemeláková, M | 3 |
| Sačková, V | 5 |
| Fedoročko, P | 8 |
| Yonar, D | 1 |
| Kılıç Süloğlu, A | 1 |
| Selmanoğlu, G | 1 |
| Sünnetçioğlu, MM | 1 |
| Gyurászová, K | 1 |
| Mikeš, J | 5 |
| Halaburková, A | 1 |
| Jendželovský, R | 5 |
| Kimáková, P | 1 |
| Solár, P | 1 |
| Fecková, B | 1 |
| Solárová, Z | 1 |
| Ilkovičová, L | 1 |
| Kello, M | 3 |
| Koval', J | 1 |
| Soucek, K | 1 |
| Procházková, J | 1 |
| Hofmanová, J | 3 |
| Kozubík, A | 3 |
| Hýžďalová, M | 1 |
| Kočí, L | 1 |
| Kovaľ, J | 1 |
| Vaculová, A | 2 |
| Kuliková, L | 1 |
| Uhrinová, I | 1 |
| Höpfner, M | 1 |
| Maaser, K | 1 |
| Theiss, A | 1 |
| Lenz, M | 1 |
| Sutter, AP | 1 |
| Kashtan, H | 1 |
| von Lampe, B | 1 |
| Riecken, EO | 1 |
| Zeitz, M | 1 |
| Scherübl, H | 1 |
| Tian, R | 1 |
| Koyabu, N | 1 |
| Morimoto, S | 1 |
| Shoyama, Y | 1 |
| Ohtani, H | 1 |
| Sawada, Y | 1 |
| Zhou, Q | 1 |
| Olivo, M | 1 |
| Lye, KY | 1 |
| Moore, S | 1 |
| Sharma, A | 1 |
| Chowbay, B | 1 |
| Kleban, J | 1 |
| Horváth, V | 1 |
| Jamborová, E | 1 |
| Colasanti, A | 1 |
| Kisslinger, A | 1 |
| Liuzzi, R | 1 |
| Quarto, M | 1 |
| Riccio, P | 1 |
| Roberti, G | 1 |
| Tramontano, D | 1 |
| Villani, F | 1 |
| Blank, M | 1 |
| Lavie, G | 1 |
| Mandel, M | 1 |
| Keisari, Y | 1 |
| Uzdensky, AB | 1 |
| Ma, LW | 1 |
| Iani, V | 1 |
| Hjortland, GO | 1 |
| Steen, HB | 1 |
| Moan, J | 1 |
| Perloff, MD | 1 |
| von Moltke, LL | 1 |
| Störmer, E | 1 |
| Shader, RI | 1 |
| Greenblatt, DJ | 1 |
1 trial available for hypericin and Adenocarcinoma
| Article | Year |
|---|---|
Enhancing the therapeutic responsiveness of photodynamic therapy with the antiangiogenic agents SU5416 and SU6668 in murine nasopharyngeal carcinoma models.
Topics: Adenocarcinoma; Angiogenesis Inhibitors; Animals; Anthracenes; Antineoplastic Agents; Chemotherapy, | 2005 |
16 other studies available for hypericin and Adenocarcinoma
| Article | Year |
|---|---|
The potential of hypericin and hyperforin for antiadhesion therapy to prevent metastasis of parental and oxaliplatin-resistant human adenocarcinoma cells (HT-29).
Topics: Adenocarcinoma; Anthracenes; Antineoplastic Combined Chemotherapy Protocols; Cell Adhesion; Cell Mov | 2018 |
An Electron paramagnetic resonance (EPR) spin labeling study in HT-29 Colon adenocarcinoma cells after Hypericin-mediated photodynamic therapy.
Topics: Adenocarcinoma; Anthracenes; Cell Membrane; Colonic Neoplasms; Computer Simulation; Cyclic N-Oxides; | 2019 |
YM155, a small molecule inhibitor of survivin expression, sensitizes cancer cells to hypericin-mediated photodynamic therapy.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Anthracenes; Antineoplastic Agents; Autophagy; Caspase 3; Ce | 2016 |
Drug membrane transporters and CYP3A4 are affected by hypericin, hyperforin or aristoforin in colon adenocarcinoma cells.
Topics: Adenocarcinoma; Anthracenes; Blotting, Western; Cell Line, Tumor; Colonic Neoplasms; Cytochrome P-45 | 2016 |
Photoactivated hypericin increases the expression of SOD-2 and makes MCF-7 cells resistant to photodynamic therapy.
Topics: 2-Methoxyestradiol; Adenocarcinoma; Anthracenes; Breast Neoplasms; Cell Line, Tumor; Estradiol; Fema | 2017 |
Drug efflux transporters, MRP1 and BCRP, affect the outcome of hypericin-mediated photodynamic therapy in HT-29 adenocarcinoma cells.
Topics: Adenocarcinoma; Anthracenes; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Ca | 2009 |
Lower sensitivity of FHC fetal colon epithelial cells to photodynamic therapy compared to HT-29 colon adenocarcinoma cells despite higher intracellular accumulation of hypericin.
Topics: Adenocarcinoma; Anthracenes; Cell Line; Colon; Colonic Neoplasms; Epithelial Cells; Fetus; Humans; M | 2011 |
Enhanced antiproliferative and apoptotic response of HT-29 adenocarcinoma cells to combination of photoactivated hypericin and farnesyltransferase inhibitor manumycin A.
Topics: Adenocarcinoma; Anthracenes; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Caspase 3 | 2011 |
The pro-apoptotic and anti-invasive effects of hypericin-mediated photodynamic therapy are enhanced by hyperforin or aristoforin in HT-29 colon adenocarcinoma cells.
Topics: Adenocarcinoma; Anthracenes; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Cycle Checkpoints; Ce | 2012 |
Hypericin activated by an incoherent light source has photodynamic effects on esophageal cancer cells.
Topics: Adenocarcinoma; Aminolevulinic Acid; Anthracenes; Antineoplastic Agents; Apoptosis; Carcinoma, Squam | 2003 |
Functional induction and de-induction of P-glycoprotein by St. John's wort and its ingredients in a human colon adenocarcinoma cell line.
Topics: Adenocarcinoma; Animals; Anthracenes; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biolo | 2005 |
Necrosis predominates in the cell death of human colon adenocarcinoma HT-29 cells treated under variable conditions of photodynamic therapy with hypericin.
Topics: Adenocarcinoma; Anthracenes; Caspase 3; Cell Cycle; Cell Proliferation; Colonic Neoplasms; Dose-Resp | 2007 |
Hypericin photosensitization of tumor and metastatic cell lines of human prostate.
Topics: Adenocarcinoma; Anthracenes; Antineoplastic Agents; Humans; Male; Neoplasm Metastasis; Perylene; Pho | 2000 |
Effects of photodynamic therapy with hypericin in mice bearing highly invasive solid tumors.
Topics: Adenocarcinoma; Animals; Anthracenes; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Squamous C | 2000 |
Intracellular localisation of hypericin in human glioblastoma and carcinoma cell lines.
Topics: Adenocarcinoma; Anthracenes; Carcinoma in Situ; Colonic Neoplasms; Female; Glioblastoma; Humans; Per | 2001 |
Saint John's wort: an in vitro analysis of P-glycoprotein induction due to extended exposure.
Topics: Adenocarcinoma; Anthracenes; Antidepressive Agents; ATP Binding Cassette Transporter, Subfamily B, M | 2001 |