hymecromone and Insulin-Resistance

hymecromone has been researched along with Insulin-Resistance* in 1 studies

Other Studies

1 other study(ies) available for hymecromone and Insulin-Resistance

Article	Year
4-Methylumbelliferone improves the thermogenic capacity of brown adipose tissue. Nature metabolism, 2019, Volume: 1, Issue:5 Therapeutic increase of brown adipose tissue (BAT) thermogenesis is of great interest as BAT activation counteracts obesity and insulin resistance. Hyaluronan (HA) is a glycosaminoglycan, found in the extracellular matrix, which is synthesized by HA synthases (Has1/Has2/Has3) from sugar precursors and accumulates in diabetic conditions. Its synthesis can be inhibited by the small molecule 4-methylumbelliferone (4-MU). Here, we show that the inhibition of HA-synthesis by 4-MU or genetic deletion of Topics: Adipose Tissue, Brown; Animals; Energy Metabolism; Hymecromone; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Thermogenesis	2019

Article

Year

4-Methylumbelliferone improves the thermogenic capacity of brown adipose tissue.

Nature metabolism, 2019, Volume: 1, Issue:5

Therapeutic increase of brown adipose tissue (BAT) thermogenesis is of great interest as BAT activation counteracts obesity and insulin resistance. Hyaluronan (HA) is a glycosaminoglycan, found in the extracellular matrix, which is synthesized by HA synthases (Has1/Has2/Has3) from sugar precursors and accumulates in diabetic conditions. Its synthesis can be inhibited by the small molecule 4-methylumbelliferone (4-MU). Here, we show that the inhibition of HA-synthesis by 4-MU or genetic deletion of

Topics: Adipose Tissue, Brown; Animals; Energy Metabolism; Hymecromone; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Thermogenesis

2019