hydroxyzine has been researched along with Syncope in 1 studies
Hydroxyzine: A histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.
hydroxyzine : A N-alkylpiperazine that is piperzine in which the nitrogens atoms are substituted by 2-(2-hydroxyethoxy)ethyl and (4-chlorophenyl)(phenyl)methyl groups respectively.
Syncope: A transient loss of consciousness and postural tone caused by diminished blood flow to the brain (i.e., BRAIN ISCHEMIA). Presyncope refers to the sensation of lightheadedness and loss of strength that precedes a syncopal event or accompanies an incomplete syncope. (From Adams et al., Principles of Neurology, 6th ed, pp367-9)
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this paper, we will report a case of drug-induced long QT syndrome associated with an H(1)-receptor antagonist, hydroxyzine, in which a mutation was identified in the HERG gene." | 7.74 | Hydroxyzine, a first generation H(1)-receptor antagonist, inhibits human ether-a-go-go-related gene (HERG) current and causes syncope in a patient with the HERG mutation. ( Ashihara, T; Ding, WG; Higashi, Y; Horie, M; Ito, M; Itoh, H; Matsuura, H; Nagaoka, I; Oka, Y; Sakaguchi, T; Takeyama, Y; Tsuji, K; Yumoto, Y; Zenda, N, 2008) |
| " In this paper, we will report a case of drug-induced long QT syndrome associated with an H(1)-receptor antagonist, hydroxyzine, in which a mutation was identified in the HERG gene." | 3.74 | Hydroxyzine, a first generation H(1)-receptor antagonist, inhibits human ether-a-go-go-related gene (HERG) current and causes syncope in a patient with the HERG mutation. ( Ashihara, T; Ding, WG; Higashi, Y; Horie, M; Ito, M; Itoh, H; Matsuura, H; Nagaoka, I; Oka, Y; Sakaguchi, T; Takeyama, Y; Tsuji, K; Yumoto, Y; Zenda, N, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sakaguchi, T | 1 |
| Itoh, H | 1 |
| Ding, WG | 1 |
| Tsuji, K | 1 |
| Nagaoka, I | 1 |
| Oka, Y | 1 |
| Ashihara, T | 1 |
| Ito, M | 1 |
| Yumoto, Y | 1 |
| Zenda, N | 1 |
| Higashi, Y | 1 |
| Takeyama, Y | 1 |
| Matsuura, H | 1 |
| Horie, M | 1 |
1 other study available for hydroxyzine and Syncope
| Article | Year |
|---|---|
Hydroxyzine, a first generation H(1)-receptor antagonist, inhibits human ether-a-go-go-related gene (HERG) current and causes syncope in a patient with the HERG mutation.
Topics: Adult; Dose-Response Relationship, Drug; Ether-A-Go-Go Potassium Channels; Female; Gene Expression R | 2008 |