hydroxyzine has been researched along with Sleep Wake Disorders in 11 studies
Hydroxyzine: A histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.
hydroxyzine : A N-alkylpiperazine that is piperzine in which the nitrogens atoms are substituted by 2-(2-hydroxyethoxy)ethyl and (4-chlorophenyl)(phenyl)methyl groups respectively.
Sleep Wake Disorders: Abnormal sleep-wake schedule or pattern associated with the CIRCADIAN RHYTHM which affect the length, timing, and/or rigidity of the sleep-wake cycle relative to the day-night cycle.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sleep difficulty is common in minimal hepatic encephalopathy (HE) and the mechanisms are not fully elucidated." | 6.73 | Histamine H1 blocker hydroxyzine improves sleep in patients with cirrhosis and minimal hepatic encephalopathy: a randomized controlled pilot trial. ( Annoni, JM; Coeytaux, A; Giostra, E; Hadengue, A; Spahr, L, 2007) |
| "To test this belief by comparing the effectiveness and prevalence of unwanted sedative effects when treating patients with chronic spontaneous urticaria (CSU) with levocetirizine 15 mg daily plus hydroxyzine 50 mg at night (levocetirizine plus hydroxyzine) vs." | 5.19 | Night-time sedating H1 -antihistamine increases daytime somnolence but not treatment efficacy in chronic spontaneous urticaria: a randomized controlled trial. ( Church, MK; Dimitrov, V; Gugutkova, M; Kralimarkova, T; Lazarova, C; Popov, TA; Staevska, M; Zuberbier, T, 2014) |
| "In light of the high prevalence of sleep disorders in patients suffering from posttraumatic stress disorder (PTSD), this study sought to compare the effect of prazosin and hydroxyzine on sleep quality in this patient group." | 2.79 | Comparing the effect of prazosin and hydroxyzine on sleep quality in patients suffering from posttraumatic stress disorder. ( Ahmadpanah, M; Bajoghli, H; Brand, S; Haghighi, M; Holsboer-Trachsler, E; Hosseini, SM; Jahangard, L; Sabzeiee, P; Torabian, S, 2014) |
| "Sleep difficulty is common in minimal hepatic encephalopathy (HE) and the mechanisms are not fully elucidated." | 2.73 | Histamine H1 blocker hydroxyzine improves sleep in patients with cirrhosis and minimal hepatic encephalopathy: a randomized controlled pilot trial. ( Annoni, JM; Coeytaux, A; Giostra, E; Hadengue, A; Spahr, L, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (54.55) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Staevska, M | 1 |
| Gugutkova, M | 1 |
| Lazarova, C | 1 |
| Kralimarkova, T | 1 |
| Dimitrov, V | 1 |
| Zuberbier, T | 1 |
| Church, MK | 1 |
| Popov, TA | 1 |
| Ahmadpanah, M | 1 |
| Sabzeiee, P | 1 |
| Hosseini, SM | 1 |
| Torabian, S | 1 |
| Haghighi, M | 1 |
| Jahangard, L | 1 |
| Bajoghli, H | 1 |
| Holsboer-Trachsler, E | 1 |
| Brand, S | 1 |
| Grattan, C | 1 |
| ANSELMO, V | 1 |
| Spahr, L | 1 |
| Coeytaux, A | 1 |
| Giostra, E | 1 |
| Hadengue, A | 1 |
| Annoni, JM | 1 |
| Fischbach, R | 1 |
| Lachnit, KS | 1 |
| Proszowski, E | 1 |
| Rieder, L | 1 |
| Balon, R | 1 |
| Kipka, EH | 1 |
| Enzenbach, R | 1 |
| Lindholm, O | 1 |
| d' Hollander, L | 1 |
| Fontaine, PJ | 1 |
| Stassart-Deryck, T | 1 |
7 trials available for hydroxyzine and Sleep Wake Disorders
| Article | Year |
|---|---|
Night-time sedating H1 -antihistamine increases daytime somnolence but not treatment efficacy in chronic spontaneous urticaria: a randomized controlled trial.
Topics: Adult; Aged; Cetirizine; Chronic Disease; Cross-Over Studies; Double-Blind Method; Drug Administrati | 2014 |
Comparing the effect of prazosin and hydroxyzine on sleep quality in patients suffering from posttraumatic stress disorder.
Topics: Adult; Central Nervous System Agents; Dreams; Female; Humans; Hydroxyzine; Interview, Psychological; | 2014 |
Histamine H1 blocker hydroxyzine improves sleep in patients with cirrhosis and minimal hepatic encephalopathy: a randomized controlled pilot trial.
Topics: Adult; Aged; Double-Blind Method; Female; Hepatic Encephalopathy; Histamine H1 Antagonists; Humans; | 2007 |
Efficacy and safety of midazolam and vesparax in treatment of sleep disorders.
Topics: Adult; Aged; Anti-Anxiety Agents; Barbiturates; Benzodiazepines; Drug Combinations; Female; Humans; | 1983 |
Midazolam in the treatment of sleep disorders in geriatric patients.
Topics: Aged; Anti-Anxiety Agents; Barbiturates; Benzodiazepines; Clinical Trials as Topic; Double-Blind Met | 1983 |
A clinical study of esucos in a mentally retarded clientele.
Topics: Adolescent; Adult; Body Weight; Brain Damage, Chronic; Child; Clinical Trials as Topic; Depression; | 1967 |
[Clinical evaluation of the action of dixyrazine on behavioral disorders in children treated in a medico-pedagogic institution].
Topics: Adolescent; Appetite; Child; Child Behavior Disorders; Child, Institutionalized; Child, Preschool; C | 1967 |
4 other studies available for hydroxyzine and Sleep Wake Disorders
| Article | Year |
|---|---|
Night-time sedating H1 antihistamine increases daytime somnolence but not treatment efficacy in chronic spontaneous urticaria: a randomized controlled study.
Topics: Female; Histamine H1 Antagonists; Humans; Hydroxyzine; Male; Sleep Wake Disorders; Urticaria | 2014 |
[Hydroxyzine in therapy by prolonged sleep].
Topics: Health Services; Humans; Hydroxyzine; Mental Disorders; Sleep Wake Disorders; Tranquilizing Agents | 1958 |
Sleep terror disorder and insomnia treated with trazodone: a case report.
Topics: Child; Female; Humans; Hydroxyzine; Imipramine; Sleep Initiation and Maintenance Disorders; Sleep Wa | 1994 |
[Hydroxyzine in anesthesia in neurosurgical intervention].
Topics: Adolescent; Adult; Aged; Blood Circulation; Cardiac Complexes, Premature; Child; Female; Humans; Hyd | 1970 |