hydroxyzine has been researched along with Sleep Initiation and Maintenance Disorders in 16 studies
Hydroxyzine: A histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.
hydroxyzine : A N-alkylpiperazine that is piperzine in which the nitrogens atoms are substituted by 2-(2-hydroxyethoxy)ethyl and (4-chlorophenyl)(phenyl)methyl groups respectively.
Sleep Initiation and Maintenance Disorders: Disorders characterized by impairment of the ability to initiate or maintain sleep. This may occur as a primary disorder or in association with another medical or psychiatric condition.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Priapism is a severe urologic condition requiring emergency management." | 5.62 | Hydroxyzine-induced priapism. ( Doyle, R; Elfessi, Z; Jhawar, A; Olson, C, 2021) |
| "A comprehensive literature search of PubMed, Embase, and CENTRAL databases was conducted to identify relevant published studies through October 2022 using the search terms: hydroxyzine and sleep, insomnia, sleep disorder or sleep initiation and maintenance disorders." | 5.41 | Efficacy and safety of hydroxyzine for sleep in adults: Systematic review. ( Brown, JN; Burgazli, CR; Rana, KB; Tillman, F, 2023) |
| "This review aims to analyze pharmacokinetic profile, plasma level variations so as the metabolism, interactions and possible relation to clinical effect of several drugs which are used primarily as anxiolytics." | 2.49 | Understanding the pharmacokinetics of anxiolytic drugs. ( Altamura, AC; Bareggi, S; Maffini, M; Mauri, MC; Moliterno, D; Paletta, S, 2013) |
| "Priapism is a severe urologic condition requiring emergency management." | 1.62 | Hydroxyzine-induced priapism. ( Doyle, R; Elfessi, Z; Jhawar, A; Olson, C, 2021) |
| "We examined trends in insomnia diagnosis and treatment among Medicare beneficiaries over an eight-year period." | 1.51 | Trends in Insomnia Diagnosis and Treatment Among Medicare Beneficiaries, 2006-2013. ( Albrecht, JS; Scharf, SM; Tom, SE; Vadlamani, A; Wickwire, EM, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (62.50) | 18.7374 |
| 1990's | 1 (6.25) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (18.75) | 24.3611 |
| 2020's | 2 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Burgazli, CR | 1 |
| Rana, KB | 1 |
| Brown, JN | 1 |
| Tillman, F | 1 |
| Olson, C | 1 |
| Jhawar, A | 1 |
| Elfessi, Z | 1 |
| Doyle, R | 1 |
| Albrecht, JS | 1 |
| Wickwire, EM | 1 |
| Vadlamani, A | 1 |
| Scharf, SM | 1 |
| Tom, SE | 1 |
| Ghanizadeh, A | 1 |
| Zare, S | 1 |
| Altamura, AC | 1 |
| Moliterno, D | 1 |
| Paletta, S | 1 |
| Maffini, M | 1 |
| Mauri, MC | 1 |
| Bareggi, S | 1 |
| GUERTLER, J | 1 |
| RICKELS, K | 1 |
| WARD, C | 1 |
| SNOW, L | 1 |
| LHERMANN, J | 1 |
| MATTHEWS, V | 1 |
| LEHMANN, HE | 2 |
| BAN, TA | 2 |
| Philipp, E | 1 |
| Kapp, W | 1 |
| Schubert, DS | 1 |
| Balon, R | 1 |
| Greenberg, LM | 1 |
| Deem, MA | 1 |
| McMahon, S | 1 |
| Linquette, M | 1 |
| Fossati, P | 1 |
| Luez, G | 1 |
3 reviews available for hydroxyzine and Sleep Initiation and Maintenance Disorders
| Article | Year |
|---|---|
Efficacy and safety of hydroxyzine for sleep in adults: Systematic review.
Topics: Humans; Hydroxyzine; Hypnotics and Sedatives; Prospective Studies; Sleep; Sleep Initiation and Maint | 2023 |
Understanding the pharmacokinetics of anxiolytic drugs.
Topics: Adrenergic beta-Antagonists; Amines; Anti-Anxiety Agents; Anticonvulsants; Anxiety Disorders; Atenol | 2013 |
Pharmacotherapy of tension and anxiety.
Topics: Anxiety; Automobile Driving; Carbamates; Cerebral Cortex; Clinical Trials as Topic; Depression; Dibe | 1972 |
4 trials available for hydroxyzine and Sleep Initiation and Maintenance Disorders
| Article | Year |
|---|---|
A preliminary randomised double-blind placebo-controlled clinical trial of hydroxyzine for treating sleep bruxism in children.
Topics: Aggression; Appetite; Child; Child, Preschool; Confusion; Double-Blind Method; Female; Headache; His | 2013 |
Comparative study of midazolam and vesparax in moderate or severe insomnia in female surgical patients.
Topics: Adult; Aged; Anti-Anxiety Agents; Barbiturates; Benzodiazepines; Dreams; Drug Combinations; Female; | 1983 |
Pharmacotherapy of tension and anxiety.
Topics: Anxiety; Automobile Driving; Carbamates; Cerebral Cortex; Clinical Trials as Topic; Depression; Dibe | 1972 |
Effects of dextroamphetamine, chlorpromazine, and hydroxyzine on behavior and performance in hyperactive children.
Topics: Child; Chlorpromazine; Clinical Trials as Topic; Depression; Dextroamphetamine; Dose-Response Relati | 1972 |
10 other studies available for hydroxyzine and Sleep Initiation and Maintenance Disorders
| Article | Year |
|---|---|
Hydroxyzine-induced priapism.
Topics: Adult; Histamine H1 Antagonists; Humans; Hydroxyzine; Male; Priapism; Sleep Initiation and Maintenan | 2021 |
Trends in Insomnia Diagnosis and Treatment Among Medicare Beneficiaries, 2006-2013.
Topics: Aged; Aged, 80 and over; Antidepressive Agents; Benzodiazepines; Drug Utilization; Female; Humans; H | 2019 |
[On the problem of insomnia in a sanatorium].
Topics: Humans; Hydroxyzine; Sleep Initiation and Maintenance Disorders | 1962 |
NIALAMIDE AND PLACEBO IN DEPRESSED PSYCHIATRIC CLINIC PATIENTS. (A CONTROLLED DOUBLE BLIND STUDY).
Topics: Depression; Depressive Disorder; Dosage Forms; Double-Blind Method; Humans; Hydroxyzine; Nialamide; | 1963 |
[CLINICAL APPLICATION OF A NEW VERY ACTIVE HYPNOTIC ASSOCIATING SODIUM SECOBARBITAL, CALCIUM BRALLOBARBITAL AND HYDROXYZINE (UC-8130)].
Topics: Barbiturates; Depression; Depressive Disorder; Geriatrics; Humans; Hydroxyzine; Hypnotics and Sedati | 1964 |
A COMPARATIVE STUDY OF THIRTEEN HYPNOTIC DRUGS.
Topics: Barbiturates; Biomedical Research; Chloral Hydrate; Chlorprothixene; Ethchlorvynol; Glutethimide; Hu | 1964 |
Hydroxyzine for acute treatment of agitation and insomnia in organic mental disorder.
Topics: Adult; Aged; Female; Humans; Hydroxyzine; Male; Middle Aged; Neurocognitive Disorders; Psychomotor A | 1984 |
Sleep terror disorder and insomnia treated with trazodone: a case report.
Topics: Child; Female; Humans; Hydroxyzine; Imipramine; Sleep Initiation and Maintenance Disorders; Sleep Wa | 1994 |
[Clinical effect of an equilibrating neuro and cardio sedative drug].
Topics: Adolescent; Adult; Aspartic Acid; Female; Humans; Hydroxyzine; Hyperthyroidism; Menopause; Phytother | 1967 |
[Controlled clinical evaluation of a combination of barbiturates and hydroxyzine].
Topics: Barbiturates; Humans; Hydroxyzine; Secobarbital; Sleep Initiation and Maintenance Disorders | 1967 |