hydroxyzine has been researched along with Rhinitis, Allergic, Seasonal in 22 studies
Hydroxyzine: A histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.
hydroxyzine : A N-alkylpiperazine that is piperzine in which the nitrogens atoms are substituted by 2-(2-hydroxyethoxy)ethyl and (4-chlorophenyl)(phenyl)methyl groups respectively.
Rhinitis, Allergic, Seasonal: Allergic rhinitis that occurs at the same time every year. It is characterized by acute CONJUNCTIVITIS with lacrimation and ITCHING, and regarded as an allergic condition triggered by specific ALLERGENS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cetirizine was well tolerated, with sedation being the most common adverse experience, increasing in frequency at higher doses." | 2.67 | Double-blind comparison of cetirizine and placebo in the treatment of seasonal rhinitis. ( Altman, R; Brandon, ML; Buchman, E; Connell, JT; Dockhorn, R; Falliers, CJ; Leese, PT; Miller, J; Wasserman, SI; Zeterberg, JM, 1991) |
| "Cetirizine is a new selective H1-antagonist." | 2.67 | Effect of cetirizine in a conjunctival provocation test with allergens. ( Pécoud, AR; Schoeneich, M, 1990) |
| "Cetirizine was rapidly absorbed with mean peak cetirizine concentrations of 427." | 2.66 | Cetirizine: a pharmacokinetic and pharmacodynamic evaluation in children with seasonal allergic rhinitis. ( Chen, XY; Simons, FE; Simons, KJ; Watson, WT, 1989) |
| "In this review of the current treatment of seasonal allergic rhinitis, the clinical studies that compare these four new second-generation H1-receptor antagonists are discussed." | 2.38 | H1-receptor antagonist treatment of seasonal allergic rhinitis. ( Kaiser, HB, 1990) |
| " To establish dose-response relationships for oral antihistamines in monkeys, we measured the suppression of wheal-and-flare reactions by two such agents, oral cetirizine (CET) 0." | 1.27 | A primate model for the evaluation of antihistamines. ( Doyle, W; Fireman, P; Skoner, D; Tanner, E, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (45.45) | 18.7374 |
| 1990's | 12 (54.55) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brooks, CD | 1 |
| Nelson, A | 1 |
| Parzyck, R | 1 |
| Maile, MH | 1 |
| Schaaf, L | 1 |
| Hendeles, L | 1 |
| Weinberger, M | 1 |
| Braunstein, G | 1 |
| Malaquin, F | 1 |
| Fajac, I | 1 |
| Melac, M | 1 |
| Frossard, N | 1 |
| Falliers, CJ | 1 |
| Brandon, ML | 1 |
| Buchman, E | 1 |
| Connell, JT | 1 |
| Dockhorn, R | 1 |
| Leese, PT | 1 |
| Miller, J | 1 |
| Wasserman, SI | 1 |
| Zeterberg, JM | 1 |
| Altman, R | 1 |
| Renton, R | 2 |
| Fidler, C | 2 |
| Rosenberg, R | 1 |
| Backhouse, CI | 1 |
| Rosenberg, RM | 1 |
| Schoeneich, M | 1 |
| Pécoud, AR | 1 |
| Panayotopoulos, SM | 1 |
| Panayotopoulou, ES | 1 |
| Klementsson, H | 1 |
| Andersson, M | 1 |
| Pipkorn, U | 1 |
| Kaiser, HB | 1 |
| Massey, WA | 1 |
| Lichtenstein, LM | 2 |
| Campoli-Richards, DM | 1 |
| Buckley, MM | 1 |
| Fitton, A | 1 |
| Naclerio, RM | 1 |
| Proud, D | 1 |
| Kagey-Sobotka, A | 1 |
| Freidhoff, L | 1 |
| Norman, PS | 1 |
| Watson, WT | 1 |
| Simons, KJ | 1 |
| Chen, XY | 1 |
| Simons, FE | 1 |
| Billardon, M | 1 |
| von Maur, K | 1 |
| Fadel, R | 1 |
| Herpin-Richard, N | 1 |
| Rihoux, JP | 1 |
| Henocq, E | 1 |
| Maddox, DE | 1 |
| Reed, CE | 1 |
| Fireman, P | 1 |
| Skoner, D | 1 |
| Tanner, E | 1 |
| Doyle, W | 1 |
| Atkins, P | 1 |
| Green, GR | 1 |
| Zweiman, B | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Nasal Ocular Reflexes Contribute to Eye Symptoms in Patients With Allergic Rhinitis[NCT00117832] | 20 participants | Interventional | 2005-03-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for hydroxyzine and Rhinitis, Allergic, Seasonal
| Article | Year |
|---|---|
H1-receptor antagonist treatment of seasonal allergic rhinitis.
Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Cetirizine; Chlorpheniramine; Clemastine; Cyprohep | 1990 |
The effects of antihistamines beyond H1 antagonism in allergic inflammation.
Topics: Benzhydryl Compounds; Cetirizine; Cyproheptadine; Dermatitis, Atopic; Histamine H1 Antagonists; Hist | 1990 |
Cetirizine. A review of its pharmacological properties and clinical potential in allergic rhinitis, pollen-induced asthma, and chronic urticaria.
Topics: Animals; Asthma; Cetirizine; Chronic Disease; Histamine H1 Antagonists; Humans; Hydroxyzine; Pollen; | 1990 |
Three new non-sedative antihistamines: worth keeping an eye open for.
Topics: Cetirizine; Cyproheptadine; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Rhinitis, All | 1990 |
15 trials available for hydroxyzine and Rhinitis, Allergic, Seasonal
| Article | Year |
|---|---|
Protective effect of hydroxyzine and phenylpropanolamine in the challenged allergic nose.
Topics: Adult; Airway Resistance; Drug Therapy, Combination; Female; Humans; Hydroxyzine; Male; Middle Aged; | 1981 |
Suppression of seasonal allergic rhinitis symptoms with daily hydroxyzine.
Topics: Adult; Clinical Trials as Topic; Female; Humans; Hydroxyzine; Immunosuppression Therapy; Male; Rhini | 1979 |
Inhibition of histamine-induced nasal obstruction by cetirizine in allergic rhinitis.
Topics: Adult; Airway Resistance; Cetirizine; Female; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzi | 1992 |
Double-blind comparison of cetirizine and placebo in the treatment of seasonal rhinitis.
Topics: Adult; Cetirizine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Histamine H1 Antag | 1991 |
Multicenter, crossover study of the efficacy and tolerability of terfenadine, 120 mg, versus cetirizine, 10 mg, in perennial allergic rhinitis.
Topics: Adult; Cetirizine; Dose-Response Relationship, Drug; Female; Histamine H1 Antagonists; Humans; Hydro | 1991 |
Multicentre, double-blind comparison of terfenadine and cetirizine in patients with seasonal allergic rhinitis.
Topics: Adult; Benzhydryl Compounds; Cetirizine; Double-Blind Method; Histamine H1 Antagonists; Humans; Hydr | 1990 |
Effect of cetirizine in a conjunctival provocation test with allergens.
Topics: Adolescent; Adult; Allergens; Cetirizine; Clinical Trials as Topic; Conjunctivitis, Allergic; Double | 1990 |
Efficacy of cetirizine in the treatment of seasonal allergic rhinoconjunctivitis.
Topics: Adult; Cetirizine; Clinical Trials as Topic; Conjunctivitis, Allergic; Double-Blind Method; Histamin | 1990 |
Allergen-induced increase in nonspecific nasal reactivity is blocked by antihistamines without a clear-cut relationship to eosinophil influx.
Topics: Allergens; Benzhydryl Compounds; Cetirizine; Double-Blind Method; Eosinophils; Histamine H1 Antagoni | 1990 |
The effects of antihistamines beyond H1 antagonism in allergic inflammation.
Topics: Benzhydryl Compounds; Cetirizine; Cyproheptadine; Dermatitis, Atopic; Histamine H1 Antagonists; Hist | 1990 |
The effect of cetirizine on early allergic response.
Topics: Albumins; Antigens; Cetirizine; Clinical Trials as Topic; Double-Blind Method; Histamine; Histamine | 1989 |
Cetirizine: a pharmacokinetic and pharmacodynamic evaluation in children with seasonal allergic rhinitis.
Topics: Cetirizine; Child; Child, Preschool; Dose-Response Relationship, Drug; Double-Blind Method; Histamin | 1989 |
[Importance of Zyrtec in the treatment of chronic urticaria and allergic rhinopathies apropos of 1168 cases seen by hospital practitioners].
Topics: Adolescent; Adult; Cetirizine; Chronic Disease; Female; Histamine H1 Antagonists; Humans; Hydroxyzin | 1989 |
Antihistamine selection in patients with allergic rhinitis.
Topics: Chlorpheniramine; Clinical Trials as Topic; Diphenhydramine; Histamine H1 Antagonists; Humans; Hydro | 1985 |
Inhibitory effect of cetirizine 2HCl on eosinophil migration in vivo.
Topics: Adult; Cell Movement; Cetirizine; Eosinophils; Female; Histamine; Histamine H1 Antagonists; Humans; | 1987 |
4 other studies available for hydroxyzine and Rhinitis, Allergic, Seasonal
| Article | Year |
|---|---|
[Cetirizine in allergic symptoms. General practice relevance and a profile of effects. Resume of current studies].
Topics: Asthma; Cetirizine; Eosinophils; Histamine H1 Antagonists; Humans; Hydroxyzine; Rhinitis, Allergic, | 1990 |
Clinical pharmacodynamics of antihistamines.
Topics: Animals; Asthma; Brain; Bronchial Provocation Tests; Cetirizine; Drug Evaluation; Electroencephalogr | 1987 |
A primate model for the evaluation of antihistamines.
Topics: Administration, Oral; Airway Resistance; Animals; Bronchial Provocation Tests; Cetirizine; Chlorphen | 1987 |
Histologic studies of human skin test responses to ragweed, compound 48-80, and histamine.
Topics: Adult; Biopsy; Eosinophils; Histamine; Humans; Hydroxyzine; Male; Mast Cells; p-Methoxy-N-methylphen | 1973 |