hydroxyzine has been researched along with Rhinitis, Allergic, Nonseasonal in 10 studies
Hydroxyzine: A histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.
hydroxyzine : A N-alkylpiperazine that is piperzine in which the nitrogens atoms are substituted by 2-(2-hydroxyethoxy)ethyl and (4-chlorophenyl)(phenyl)methyl groups respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nonsedating antihistamines (nsAHs) are recommended as first-line therapeutics for the treatment of mast cell-driven disorders, including allergic rhinitis and urticaria." | 5.14 | Suppression of histamine- and allergen-induced skin reactions: comparison of first- and second-generation antihistamines. ( dos Santos, RV; Lima, HC; Magerl, M; Mlynek, A, 2009) |
| "The second-generation H1-receptor antagonists terfenadine, astemizole, loratadine, and cetirizine are important first-line drugs for the relief of symptoms in patients with allergic rhinoconjunctivitis or chronic urticaria and may eventually supplant the potentially sedating first-generation H1-receptor antagonists in the treatment of these disorders." | 4.78 | Recent advances in H1-receptor antagonist treatment. ( Simons, FE, 1990) |
| "Cetirizine was well tolerated, and the frequency of somnolence was not significantly greater in patients receiving this drug than in those given placebo." | 2.67 | Efficacy and safety of cetirizine therapy in perennial allergic rhinitis. ( Altman, RA; Berman, BA; Buchman, E; Dockhorn, RJ; Leese, PT; Love, SJ; Mansmann, HC; Middleton, E, 1992) |
| "Cetirizine is a major metabolite of hydroxyzine that has little anticholinergic activity and causes significantly less sedation." | 2.38 | Perennial allergic rhinitis: clinical efficacy of a new antihistamine. ( Berman, BA, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (40.00) | 18.7374 |
| 1990's | 5 (50.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| dos Santos, RV | 1 |
| Magerl, M | 1 |
| Mlynek, A | 1 |
| Lima, HC | 1 |
| Wong, L | 1 |
| Hendeles, L | 1 |
| Weinberger, M | 1 |
| Mansmann, HC | 1 |
| Altman, RA | 1 |
| Berman, BA | 2 |
| Buchman, E | 1 |
| Dockhorn, RJ | 1 |
| Leese, PT | 1 |
| Love, SJ | 1 |
| Middleton, E | 1 |
| Lobaton, P | 1 |
| Moreno, F | 1 |
| Coulie, P | 1 |
| Simons, FE | 1 |
| Boniver, R | 1 |
| Arendt, C | 1 |
| Billardon, M | 1 |
| von Maur, K | 1 |
2 reviews available for hydroxyzine and Rhinitis, Allergic, Nonseasonal
| Article | Year |
|---|---|
Perennial allergic rhinitis: clinical efficacy of a new antihistamine.
Topics: Benzhydryl Compounds; Cetirizine; Diphenhydramine; Dose-Response Relationship, Drug; Histamine H1 An | 1990 |
Recent advances in H1-receptor antagonist treatment.
Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Cetirizine; Cyproheptadine; Histamine H1 Antagonis | 1990 |
7 trials available for hydroxyzine and Rhinitis, Allergic, Nonseasonal
| Article | Year |
|---|---|
Suppression of histamine- and allergen-induced skin reactions: comparison of first- and second-generation antihistamines.
Topics: Adult; Allergens; Animals; Dermatophagoides pteronyssinus; Dibenzazepines; Double-Blind Method; Fema | 2009 |
Pharmacologic prophylaxis of allergic rhinitis: relative efficacy of hydroxyzine and chlorpheniramine.
Topics: Adolescent; Adult; Aged; Chlorpheniramine; Clinical Trials as Topic; Female; Humans; Hydroxyzine; Ma | 1981 |
Efficacy and safety of cetirizine therapy in perennial allergic rhinitis.
Topics: Adult; Cetirizine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy; Histamine H1 | 1992 |
Comparison of cetirizine with astemizole in the treatment of perennial allergic rhinitis and study of the concomitant effect on histamine and allergen-induced wheal responses.
Topics: Adult; Astemizole; Benzimidazoles; Cetirizine; Double-Blind Method; Histamine H1 Antagonists; Humans | 1990 |
[Evaluation of cetirizine and of terfenadine in the treatment of perennial allergic rhinitis].
Topics: Adolescent; Adult; Benzhydryl Compounds; Cetirizine; Clinical Trials as Topic; Double-Blind Method; | 1989 |
[Importance of Zyrtec in the treatment of chronic urticaria and allergic rhinopathies apropos of 1168 cases seen by hospital practitioners].
Topics: Adolescent; Adult; Cetirizine; Chronic Disease; Female; Histamine H1 Antagonists; Humans; Hydroxyzin | 1989 |
Antihistamine selection in patients with allergic rhinitis.
Topics: Chlorpheniramine; Clinical Trials as Topic; Diphenhydramine; Histamine H1 Antagonists; Humans; Hydro | 1985 |
1 other study available for hydroxyzine and Rhinitis, Allergic, Nonseasonal
| Article | Year |
|---|---|
[Cetirizine in allergic symptoms. General practice relevance and a profile of effects. Resume of current studies].
Topics: Asthma; Cetirizine; Eosinophils; Histamine H1 Antagonists; Humans; Hydroxyzine; Rhinitis, Allergic, | 1990 |