hydroxyzine has been researched along with Pregnancy in 59 studies
Hydroxyzine: A histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.
hydroxyzine : A N-alkylpiperazine that is piperzine in which the nitrogens atoms are substituted by 2-(2-hydroxyethoxy)ethyl and (4-chlorophenyl)(phenyl)methyl groups respectively.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
Excerpt | Relevance | Reference |
---|---|---|
"A majority of patients experience pruritus, nausea and/or emesis following epidural morphine administration post-cesarean section." | 9.07 | Epidural morphine pruritus reduction with hydroxyzine in parturients. ( Ackerman, WE; Bellinger, K; Juneja, MM, 1991) |
"One hundred twenty women were followed after exposure to either hydroxyzine or cetirizine during pregnancy." | 7.69 | Prospective controlled study of hydroxyzine and cetirizine in pregnancy. ( Bailey, B; Baillie, M; Einarson, A; Jung, G; Koren, G; Spizzirri, D, 1997) |
"A majority of patients experience pruritus, nausea and/or emesis following epidural morphine administration post-cesarean section." | 5.07 | Epidural morphine pruritus reduction with hydroxyzine in parturients. ( Ackerman, WE; Bellinger, K; Juneja, MM, 1991) |
" Elevated bile acid levels confirmed a diagnosis of intrahepatic cholestasis of pregnancy, and ursodeoxycholic acid therapy was initiated." | 3.77 | Primary dermatologic findings with early-onset intrahepatic cholestasis of pregnancy. ( Chao, TT; Sheffield, JS, 2011) |
"One hundred twenty women were followed after exposure to either hydroxyzine or cetirizine during pregnancy." | 3.69 | Prospective controlled study of hydroxyzine and cetirizine in pregnancy. ( Bailey, B; Baillie, M; Einarson, A; Jung, G; Koren, G; Spizzirri, D, 1997) |
"To our knowledge, this is the first report of a neonatal withdrawal syndrome associated with maternal usage of 600 mg daily of hydroxyzine hydrochloride throughout pregnancy." | 3.65 | Neonatal withdrawal syndrome associated with hydroxyzine hydrochloride. ( Prenner, BM, 1977) |
"Vomiting was significantly more frequent in the placebo-treated group [0." | 2.64 | A controlled trial of antiemetics in abortion by PGF2alpha and laminaria. ( Federschneider, JM; Kaul, AF; Stubblefield, PG, 1978) |
"Current treatment for toxoplasmosis commonly have high cytotoxic side effects on host and require long durations ranging from one week to more than one year." | 2.61 | Recent progress on anti-Toxoplasma drugs discovery: Design, synthesis and screening. ( Deng, Y; Li, CH; Wu, T; Zhai, SQ, 2019) |
" The objective was to measure the rate of adverse pregnancy outcomes." | 2.50 | The fetal safety of cetirizine: an observational cohort study and meta-analysis. ( Boskovic, R; Djokanovic, N; Etwel, F; Koren, G; Martinovic, J; Moretti, ME, 2014) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 45 (76.27) | 18.7374 |
1990's | 3 (5.08) | 18.2507 |
2000's | 3 (5.08) | 29.6817 |
2010's | 8 (13.56) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Deng, Y | 1 |
Wu, T | 1 |
Zhai, SQ | 1 |
Li, CH | 1 |
Veiga, VF | 1 |
Santos, F | 1 |
Antunes, A | 1 |
Duarte, I | 1 |
Pevtichev, S | 1 |
Dimitrova, V | 1 |
Etwel, F | 1 |
Djokanovic, N | 1 |
Moretti, ME | 1 |
Boskovic, R | 1 |
Martinovic, J | 1 |
Koren, G | 2 |
Fujii, Y | 1 |
Chao, TT | 1 |
Sheffield, JS | 1 |
Othman, M | 1 |
Jones, L | 1 |
Neilson, JP | 1 |
GIANNI, T | 1 |
SAVONA, B | 1 |
PERRICONE, G | 1 |
MAYER, M | 1 |
ESPAGNO, G | 1 |
MULLA, N | 1 |
WOYTON, J | 1 |
CHILDERS, J | 1 |
GORTZ, RV | 1 |
INMON, WB | 1 |
SYLVESTER, WR | 1 |
MARTINS, AD | 1 |
ARANTES, JC | 1 |
CITTERIO, P | 1 |
STEFANINI, U | 1 |
DEJONG, RH | 1 |
GORDON, EM | 1 |
NELSON, HB | 1 |
LUBE, J | 1 |
MUELLENDER, H | 1 |
Jantjes, L | 1 |
Strümpher, J | 1 |
Kotzé, WJ | 1 |
Zarebska, A | 1 |
Datta, S | 1 |
Alper, MH | 1 |
McKenzie, R | 1 |
Wadhwa, RK | 2 |
Uy, NT | 1 |
Phitayakorn, P | 1 |
Tantisira, B | 2 |
Sinchioco, C | 1 |
Taylor, FH | 1 |
Amato, G | 1 |
Corsini, D | 1 |
Pelliccia, E | 1 |
Einarson, A | 1 |
Bailey, B | 1 |
Jung, G | 1 |
Spizzirri, D | 1 |
Baillie, M | 1 |
Michel, M | 1 |
Dompmartin, A | 1 |
Louvet, S | 1 |
Szczurko, C | 1 |
Castel, B | 1 |
Leroy, D | 1 |
Normand, F | 1 |
Armingaud, P | 1 |
Estève, E | 1 |
Petrie, RH | 2 |
Yeh, SY | 1 |
Murata, Y | 1 |
Paul, RH | 2 |
Hon, EH | 2 |
Barron, BA | 1 |
Johnson, RJ | 1 |
Kaul, AF | 1 |
Federschneider, JM | 1 |
Stubblefield, PG | 1 |
Prenner, BM | 1 |
Wu, R | 1 |
Miller, FC | 1 |
Sacks, DA | 1 |
Sugarman, R | 1 |
Juneja, MM | 1 |
Ackerman, WE | 1 |
Bellinger, K | 1 |
Schuller, DE | 1 |
Turkewitz, D | 1 |
Sadovsky, E | 1 |
Weinstein, D | 1 |
Pfeifer, Y | 1 |
Polishuk, WZ | 1 |
Sulman, FG | 1 |
Clark, RB | 1 |
Reisner, JG | 1 |
King, CT | 2 |
Howell, J | 1 |
Steffek, AJ | 1 |
Derr, JE | 1 |
Standley, K | 1 |
Soule, AB | 1 |
Copans, SA | 1 |
Duchowny, MS | 1 |
Walker, BE | 1 |
Patterson, A | 1 |
Yassemi, N | 1 |
Csapo, AI | 1 |
Kivikoski, A | 1 |
Wiest, WG | 1 |
Simionescu, S | 2 |
Bordeianu, A | 2 |
Stancu, C | 2 |
Daniel, B | 2 |
Pintilescu, V | 2 |
Wingate, MB | 1 |
Wingate, L | 1 |
Iffy, L | 1 |
Freundlich, J | 1 |
Gottsegen, D | 1 |
Mateescu-Cantuniari, A | 1 |
Erez, S | 1 |
Schifrin, BS | 1 |
Dirim, O | 1 |
Dees, HC | 1 |
Spellacy, WN | 1 |
Shattuck, CA | 1 |
Loffer, FD | 1 |
Malkasian, GD | 1 |
Smith, RA | 1 |
Decker, DG | 1 |
Hardesty, WH | 1 |
Withöft, W | 1 |
Saurwein, A | 1 |
Semler, WL | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Intravenous Injection of Diazepam at the Beginning of Active Phase of Labor[NCT02232035] | Phase 2 | 400 participants (Anticipated) | Interventional | 2014-09-30 | Not yet recruiting | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
9 reviews available for hydroxyzine and Pregnancy
Article | Year |
---|---|
Recent progress on anti-Toxoplasma drugs discovery: Design, synthesis and screening.
Topics: Animals; Antiprotozoal Agents; Drug Discovery; Female; Humans; Pregnancy; Toxoplasma; Toxoplasmosis | 2019 |
[Intrahepatic cholestasis of pregnancy].
Topics: Anticholesteremic Agents; Bile Ducts; Cholagogues and Choleretics; Cholestasis, Intrahepatic; Choles | 2013 |
The fetal safety of cetirizine: an observational cohort study and meta-analysis.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Adult; Cetirizine; Female; Histamine H1 Antagoni | 2014 |
Drugs to avoid in pregnant women with allergies.
Topics: Abnormalities, Drug-Induced; Arrhythmias, Cardiac; Basal Ganglia Diseases; Female; Histamine H1 Anta | 2016 |
Prevention of nausea and vomiting during termination of pregnancy.
Topics: Abortion, Therapeutic; Antiemetics; Benzimidazoles; Dexamethasone; Dilatation and Curettage; Droperi | 2010 |
Non-opioid drugs for pain management in labour.
Topics: Analgesia, Obstetrical; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non- | 2012 |
Anesthesia for cesarean section.
Topics: Anesthesia, Epidural; Anesthesia, General; Anesthesia, Intravenous; Anesthesia, Spinal; Anesthetics; | 1980 |
Adverse effects of antihistamines.
Topics: Adolescent; Adult; Aged; Asthma; Brompheniramine; Central Nervous System; Child, Preschool; Chlorphe | 1986 |
Analgesia during labor: effect on the fetus and neonate.
Topics: Acidosis; Alphaprodine; Anesthesia, Inhalation; Anesthesia, Obstetrical; Anesthetics; Apgar Score; B | 1974 |
8 trials available for hydroxyzine and Pregnancy
Article | Year |
---|---|
Antiemetic effectiveness of intramuscular hydroxyzine compared with intramuscular droperidol.
Topics: Abortion, Induced; Antiemetics; Double-Blind Method; Droperidol; Drug Evaluation; Female; Humans; Hy | 1981 |
A controlled trial of antiemetics in abortion by PGF2alpha and laminaria.
Topics: Abortion, Induced; Adolescent; Adult; Amnion; Analgesics, Opioid; Antiemetics; Clinical Trials as To | 1978 |
Epidural morphine pruritus reduction with hydroxyzine in parturients.
Topics: Adult; Analgesia, Epidural; Cesarean Section; Female; Humans; Hydroxyzine; Injections, Epidural; Inj | 1991 |
Hydroxyzine for controlling postpartum anxiety: a double-blind study.
Topics: Anxiety; Clinical Trials as Topic; Female; Humans; Hydroxyzine; Obstetric Labor Complications; Pregn | 1967 |
Double-blind evaluation of hydroxyzine as an antiemetic in pregancy.
Topics: Antiemetics; Clinical Trials as Topic; Female; Humans; Hydroxyzine; Hyperemesis Gravidarum; Nausea; | 1971 |
A study of the effect of phenergan and vistaril in combination with demerol on labor and delivery.
Topics: Anesthesia, Obstetrical; Clinical Trials as Topic; Female; Georgia; Humans; Hydroxyzine; Meperidine; | 1965 |
A double-blind study of the comparative effects of meperidine with secobarbital, hydroxyzine, or a placebo on labor and delivery.
Topics: Adult; Anesthesia, Obstetrical; Clinical Trials as Topic; Delivery, Obstetric; Female; Humans; Hydro | 1966 |
Comparison of hydroxyzine-meperidine and promethazine-meperidine for analgesia during labor.
Topics: Anesthesia, Obstetrical; Blood Pressure; Clinical Trials as Topic; Female; Fetus; Humans; Hydroxyzin | 1967 |
42 other studies available for hydroxyzine and Pregnancy
Article | Year |
---|---|
Phemphigoid gestationis.
Topics: Adult; Antipruritics; Female; Histamine H1 Antagonists; Humans; Hydroxyzine; Pemphigoid Gestationis; | 2018 |
[Pruritic urticarial papules and plaques of pregnancy].
Topics: Adult; Anti-Inflammatory Agents; Antipruritics; Betamethasone; Female; Humans; Hydrocortisone; Hydro | 2008 |
Primary dermatologic findings with early-onset intrahepatic cholestasis of pregnancy.
Topics: Betamethasone; Bile Acids and Salts; Cholagogues and Choleretics; Cholestasis, Intrahepatic; Deliver | 2011 |
[Hydroxyzine hydrochloride (atarax) in the field of obstetrics and gynecology].
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Female; Genital Diseases, Female; Gynecology; Human | 1957 |
[Hydroxyzine in obstetrics; value of the use of a neuroleptic agent in drug therapy of inertia with posterior pituitary extracts].
Topics: Antipsychotic Agents; Dystocia; Female; Humans; Hydroxyzine; Obstetrics; Pituitary Gland; Pituitary | 1958 |
[Hydroxyzine in labor].
Topics: Female; Humans; Hydroxyzine; Labor, Obstetric; Pregnancy; Tranquilizing Agents; Work | 1959 |
Clinical evaluation of hydroxyzine hydrochloride in the management of labor.
Topics: Disease Management; Female; Humans; Hydroxyzine; Labor, Obstetric; Pregnancy; Work | 1961 |
[Attempted therapy of vomiting in pregnancy with atarax].
Topics: Female; Hydroxyzine; Pregnancy; Pregnancy Complications; Vomiting | 1959 |
Hydroxyzine in labor and delivery.
Topics: Anesthesia; Anesthesia, Obstetrical; Delivery, Obstetric; Female; Humans; Hydroxyzine; Labor, Obstet | 1961 |
[A new therapeutic compound in the treatment of after-pains].
Topics: Acetanilides; Female; Humans; Hydroxyzine; Labor Pain; Muscle Relaxants, Central; Postpartum Period; | 1961 |
A STUDY OF THE EFFECT OF HYDROXYZINE HYDROCHLORIDE ON LABOR AND DELIVERY.
Topics: Anesthesia; Anesthesia, Obstetrical; Delivery, Obstetric; Female; Humans; Hydroxyzine; Labor, Obstet | 1963 |
NAUSEA AND VOMITING IN PREGNANCY.
Topics: Female; Humans; Hydroxyzine; Nausea; Pregnancy; Pregnancy Complications; Prochlorperazine; Toxicolog | 1964 |
[RESERPINE IN LABOR].
Topics: Adjuvants, Anesthesia; Anesthesia; Anesthesia, Obstetrical; Female; Glutethimide; Humans; Hydroxyzin | 1964 |
[EXPERIENCE WITH AN ASSOCIATION OF AN ANALGESIC AND TRANQUILIZING AGENT IN LABOR].
Topics: Analgesics; Anesthesia; Anesthesia, Obstetrical; Female; Humans; Hydroxyzine; Hypnotics and Sedative | 1964 |
ARTERIAL CARBON DIOXIDE AND OXYGEN TENSIONS DURING SPINAL BLOCK.
Topics: Anesthesia, Conduction; Anesthesia, Obstetrical; Anesthesia, Spinal; Blood Gas Analysis; Carbon Diox | 1965 |
A DOUBLE BLIND STUDY OF THE EFFECT OF TRANQUILIZERS DURING LABOR.
Topics: Anesthesia; Anesthesia, Obstetrical; Biomedical Research; Double-Blind Method; Drug Therapy; Female; | 1965 |
[Clinical experiences with the problem of the reduction of pain and the shortening of labor with sanaestin, sanaestin/sparcotin, and atarax].
Topics: Anesthesia; Anesthesia, Obstetrical; Female; Humans; Hydroxyzine; Labor, Obstetric; Pain; Pregnancy | 1959 |
[Atarax in obstetrics].
Topics: Female; Humans; Hydroxyzine; Labor, Obstetric; Obstetrics; Pregnancy; Pregnanediones; Work | 1962 |
The experience of childbrith in first-time mothers who received narcotic analgesics during the first stage of labour.
Topics: Adaptation, Psychological; Analgesia, Obstetrical; Analgesics, Opioid; Attitude to Health; Drug Ther | 2007 |
[Effect of hydroxyzine on the spleen of female rats during pregnancy].
Topics: Alkaline Phosphatase; Animals; Dose-Response Relationship, Drug; Enzyme Activation; Female; Hydroxyz | 1983 |
[Personal experience with a combination of Althesin and Atarax in caesarean section].
Topics: Alfaxalone Alfadolone Mixture; Anesthesia, Obstetrical; Cesarean Section; Drug Combinations; Female; | 1980 |
Prospective controlled study of hydroxyzine and cetirizine in pregnancy.
Topics: Abortion, Spontaneous; Abortion, Therapeutic; Alcohol Drinking; Anti-Allergic Agents; Birth Rate; Bi | 1997 |
Skin reactions to hydroxyzine.
Topics: Adult; Aged; Dermatitis, Atopic; Drug Eruptions; Female; Histamine H1 Antagonists; Humans; Hydroxyzi | 1997 |
[Dyshidrosis and acral purpura during polymorphic dermatitis in pregnancy: 2 cases].
Topics: Administration, Topical; Adult; Anti-Inflammatory Agents; Antipruritics; Betamethasone; Biopsy; Drug | 2001 |
The effect of drugs on fetal heart rate variability.
Topics: Analgesics, Opioid; Female; Fetal Heart; Heart Rate; Humans; Hydroxyzine; Labor, Obstetric; Magnesiu | 1978 |
Neonatal withdrawal syndrome associated with hydroxyzine hydrochloride.
Topics: Adult; Female; Fetal Blood; Humans; Hydroxyzine; Infant, Newborn; Infant, Newborn, Diseases; Pregnan | 1977 |
The effect of drugs on uterine activity.
Topics: Adolescent; Adult; Alphaprodine; Female; Humans; Hydroxyzine; Labor, Obstetric; Magnesium Sulfate; M | 1976 |
Prevention of serotonin abortion by serotonin antagonists in rats.
Topics: Abortion, Induced; Animals; Atropine; Benzocycloheptenes; Dimethylamines; Ergolines; Female; Gestati | 1973 |
Teratogenic effect of buclizine and hydroxyzine in the rat and chlorcyclizine in the mouse.
Topics: Abnormalities, Drug-Induced; Animals; Antiemetics; Female; Histamine H1 Antagonists; Hydroxyzine; Mi | 1966 |
The comparative pathogenesis of experimentally induced cleft palate.
Topics: Abnormalities, Drug-Induced; Animals; Cleft Palate; Female; Hydroxyzine; Maxillofacial Development; | 1966 |
Letter: Preabortion medication.
Topics: Abortion, Therapeutic; Anesthesia, General; Diazepam; Female; Humans; Hydroxyzine; Nausea; Pregnancy | 1974 |
Local-regional anesthesia during childbirth: effect on newborn behaviors.
Topics: Anesthesia, Conduction; Anesthesia, Local; Anesthesia, Obstetrical; Apgar Score; Birth Weight; Bupiv | 1974 |
Induction of cleft palate in mice by tranquilizers and barbiturates.
Topics: Animals; Barbiturates; Chlordiazepoxide; Chlorpromazine; Cleft Palate; Diazepam; Female; Hydroxyzine | 1974 |
Use of atarax with ketamine anaesthesia in obstetrics.
Topics: Anesthesia, Inhalation; Anesthesia, Obstetrical; Atropine; Cesarean Section; Female; Humans; Hydroxy | 1974 |
Massive initial prostaglandin impact in postconceptional therapy.
Topics: Abortion, Induced; Adult; Amniotic Fluid; Estradiol; Female; Humans; Hydroxyzine; Injections; Meperi | 1972 |
[Studies of the influence of the non-specific pharmacodynamic action of hydroxyzine on the sex function equilibration mechanism].
Topics: Animals; Estrus; Female; Genitalia, Female; Hydroxyzine; Ovary; Pregnancy; Rats; Uterus | 1973 |
The effect of epidural analgesia upon fetal and neonatal status.
Topics: Analgesia; Analgesics; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthetics; Apgar Score; Bloo | 1974 |
[The nonspecific pharmacodynamic action of certain psychotropic drugs of different structure and classification on the equilibrium of sexual function].
Topics: Animals; Antidepressive Agents; Chlordiazepoxide; Estrus; Female; Hydroxyzine; Meprobamate; Ovary; P | 1974 |
Inadvertent intra-arterial injection.
Topics: Adult; Female; Humans; Hydroxyzine; Injections, Intra-Arterial; Injections, Intravenous; Pregnancy; | 1970 |
[Panel discussion: re-evaluation of premedication].
Topics: Adjuvants, Anesthesia; Anesthesia, Obstetrical; Atropine; Female; Haloperidol; Humans; Hydroxyzine; | 1967 |
[Effect of hydroxizine on labor pains and delivery course. Contribution to medicinal labor control].
Topics: Female; Humans; Hydroxyzine; Labor, Obstetric; Pregnancy | 1968 |
Use of Hydroxyzine in management of labor.
Topics: Adolescent; Adult; Anesthesia, Obstetrical; Female; Humans; Hydroxyzine; Meperidine; Pregnancy | 1965 |