Page last updated: 2024-10-28

hydroxyzine and Nausea

hydroxyzine has been researched along with Nausea in 15 studies

Hydroxyzine: A histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.
hydroxyzine : A N-alkylpiperazine that is piperzine in which the nitrogens atoms are substituted by 2-(2-hydroxyethoxy)ethyl and (4-chlorophenyl)(phenyl)methyl groups respectively.

Nausea: An unpleasant sensation in the stomach usually accompanied by the urge to vomit. Common causes are early pregnancy, sea and motion sickness, emotional stress, intense pain, food poisoning, and various enteroviruses.

Research Excerpts

ExcerptRelevanceReference
"The efficacy and safety of granisetron alone (group G) and granisetron plus hydroxyzine hydrochloride (group G/H) as prophylactic therapy for acute and delayed nausea and vomiting were evaluated in an open trial in head and neck cancer patients undergoing chemotherapy with cisplatin."9.08Comparison of granisetron alone and granisetron plus hydroxyzine hydrochloride for prophylactic treatment of emesis induced by cisplatin chemotherapy. ( Enomoto, H; Furukawa, M; Furukawa, S; Kokatsu, T; Kubota, A; Tsukuda, M, 1995)
"The comparative study among granisetron alone and granisetron combined with hydroxyzine hydrochloride or dexamethasone was undertaken for the prevention of nausea and vomiting during chemotherapy including cisplatin in patients with advanced head and neck carcinomas."9.08[Comparison of granisetron alone and granisetron plus dexamethasone or hydroxyzine hydrochloride for the prevention of nausea and vomiting during chemotherapy including cisplatin]. ( Enomoto, H; Furukawa, M; Ikema, Y; Kawai, S; Kohno, H; Kubota, A; Makino, Y; Matsuda, H; Tsukuda, M; Yago, T, 1995)
"We performed a clinical evaluation on the antiemetic profile and the plasma concentration of Azasetron Hydrochloride (a new selective 5-HT3 receptor antagonist), in transcatheter arterial chemoembolization using CDDP for unresectable hepatocellular carcinoma."9.08[Clinical evaluation of Azasetron Hydrochloride: a new selective 5-HT3 receptor antagonist--antiemetic profile and plasma concentration in transcatheter arterial chemoembolization using CDDP for unresectable hepatocellular carcinoma]. ( Beppu, T; Doi, K; Egami, H; Kudo, S; Kuramoto, M; Masuda, Y; Matsuda, T; Ogawa, M; Ohara, C; Yamanaka, T, 1998)
"In this study, the utility and safety of granisetron alone (Group G) and granisetron plus hydroxyzine hydrochloride (Group G/H) for nausea and vomiting were evaluated in patients with head and neck cancer treated by cisplatin-containing chemotherapy."9.07[Comparison of granisetron alone and granisetron plus hydroxyzine hydrochloride for the prophylactic treatment of emesis induced by cisplatin-containing chemotherapy]. ( Enomoto, H; Furukawa, M; Furukawa, S; Kohno, H; Kokatsu, T; Kubota, A; Tsukuda, M, 1993)
"The efficacy and safety of granisetron alone (group G) and granisetron plus hydroxyzine hydrochloride (group G/H) as prophylactic therapy for acute and delayed nausea and vomiting were evaluated in an open trial in head and neck cancer patients undergoing chemotherapy with cisplatin."5.08Comparison of granisetron alone and granisetron plus hydroxyzine hydrochloride for prophylactic treatment of emesis induced by cisplatin chemotherapy. ( Enomoto, H; Furukawa, M; Furukawa, S; Kokatsu, T; Kubota, A; Tsukuda, M, 1995)
"The comparative study among granisetron alone and granisetron combined with hydroxyzine hydrochloride or dexamethasone was undertaken for the prevention of nausea and vomiting during chemotherapy including cisplatin in patients with advanced head and neck carcinomas."5.08[Comparison of granisetron alone and granisetron plus dexamethasone or hydroxyzine hydrochloride for the prevention of nausea and vomiting during chemotherapy including cisplatin]. ( Enomoto, H; Furukawa, M; Ikema, Y; Kawai, S; Kohno, H; Kubota, A; Makino, Y; Matsuda, H; Tsukuda, M; Yago, T, 1995)
"We performed a clinical evaluation on the antiemetic profile and the plasma concentration of Azasetron Hydrochloride (a new selective 5-HT3 receptor antagonist), in transcatheter arterial chemoembolization using CDDP for unresectable hepatocellular carcinoma."5.08[Clinical evaluation of Azasetron Hydrochloride: a new selective 5-HT3 receptor antagonist--antiemetic profile and plasma concentration in transcatheter arterial chemoembolization using CDDP for unresectable hepatocellular carcinoma]. ( Beppu, T; Doi, K; Egami, H; Kudo, S; Kuramoto, M; Masuda, Y; Matsuda, T; Ogawa, M; Ohara, C; Yamanaka, T, 1998)
" The anti-nauseant hydroxyzine (H) was coadministered in both treatment groups."5.08Double-blind, multicenter trial to compare the efficacy of intramuscular dihydroergotamine plus hydroxyzine versus intramuscular meperidine plus hydroxyzine for the emergency department treatment of acute migraine headache. ( Barton, CW; Carleton, SC; Chelly, JE; Chudnofsky, CR; Johnson, G; Morris, DL; Pietrzak, MP; Rhee, KJ; Rosenberg, J; Shesser, RF; Starkman, S; Van Valen, MK, 1998)
"In this study, the utility and safety of granisetron alone (Group G) and granisetron plus hydroxyzine hydrochloride (Group G/H) for nausea and vomiting were evaluated in patients with head and neck cancer treated by cisplatin-containing chemotherapy."5.07[Comparison of granisetron alone and granisetron plus hydroxyzine hydrochloride for the prophylactic treatment of emesis induced by cisplatin-containing chemotherapy]. ( Enomoto, H; Furukawa, M; Furukawa, S; Kohno, H; Kokatsu, T; Kubota, A; Tsukuda, M, 1993)
"Chloral hydrate was safe and relatively effective, causing more satisfactory behavioral and physiological outcomes than a placebo."2.73A randomized double-blinded trial of chloral hydrate with or without hydroxyzine versus placebo for pediatric dental sedation. ( da Costa, LR; da Costa, PS; Lima, AR, 2007)
"The study investigated patient discharge parameters and postdischarge adverse events after discharge among children who received oral conscious sedation for dental treatment."1.42Oral Sedation Postdischarge Adverse Events in Pediatric Dental Patients. ( Huang, A; Tanbonliong, T, 2015)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19908 (53.33)18.7374
1990's5 (33.33)18.2507
2000's1 (6.67)29.6817
2010's1 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Huang, A1
Tanbonliong, T1
MOORE, CH1
SYLVESTER, WR1
da Costa, LR1
da Costa, PS1
Lima, AR1
Baker, JP1
McKenzie, R1
Wadhwa, RK2
Uy, NT1
Phitayakorn, P1
Tantisira, B2
Sinchioco, C1
Taylor, FH1
Tsukuda, M3
Furukawa, S2
Kokatsu, T2
Enomoto, H3
Kubota, A3
Furukawa, M3
Kohno, H2
Kawai, S1
Yago, T1
Matsuda, H1
Ikema, Y1
Makino, Y1
Beppu, T1
Ogawa, M1
Yamanaka, T1
Egami, H1
Ohara, C1
Masuda, Y1
Kudo, S1
Kuramoto, M1
Doi, K1
Matsuda, T1
Carleton, SC1
Shesser, RF1
Pietrzak, MP1
Chudnofsky, CR1
Starkman, S1
Morris, DL1
Johnson, G1
Rhee, KJ1
Barton, CW1
Chelly, JE1
Rosenberg, J1
Van Valen, MK1
Kipka, EH1
Enzenbach, R1
Bernhoff, A1
Jakt, L1
Erez, S1
Schifrin, BS1
Dirim, O1

Trials

8 trials available for hydroxyzine and Nausea

ArticleYear
A randomized double-blinded trial of chloral hydrate with or without hydroxyzine versus placebo for pediatric dental sedation.
    Brazilian dental journal, 2007, Volume: 18, Issue:4

    Topics: Anesthesia, Dental; Blood Pressure; Child Behavior; Child, Preschool; Chloral Hydrate; Conscious Sed

2007
Antiemetic effectiveness of intramuscular hydroxyzine compared with intramuscular droperidol.
    Anesthesia and analgesia, 1981, Volume: 60, Issue:11

    Topics: Abortion, Induced; Antiemetics; Double-Blind Method; Droperidol; Drug Evaluation; Female; Humans; Hy

1981
Comparison of granisetron alone and granisetron plus hydroxyzine hydrochloride for prophylactic treatment of emesis induced by cisplatin chemotherapy.
    European journal of cancer (Oxford, England : 1990), 1995, Volume: 31A, Issue:10

    Topics: Acute Disease; Adult; Aged; Antiemetics; Antineoplastic Agents; Cisplatin; Drug Therapy, Combination

1995
[Comparison of granisetron alone and granisetron plus dexamethasone or hydroxyzine hydrochloride for the prevention of nausea and vomiting during chemotherapy including cisplatin].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1995, Volume: 22, Issue:10

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Cisplatin; Dexamethasone; Drug Therapy, Combination; Female;

1995
[Comparison of granisetron alone and granisetron plus hydroxyzine hydrochloride for the prophylactic treatment of emesis induced by cisplatin-containing chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:13

    Topics: Adult; Aged; Cisplatin; Drug Therapy, Combination; Female; Granisetron; Head and Neck Neoplasms; Hum

1993
[Clinical evaluation of Azasetron Hydrochloride: a new selective 5-HT3 receptor antagonist--antiemetic profile and plasma concentration in transcatheter arterial chemoembolization using CDDP for unresectable hepatocellular carcinoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1998, Volume: 25, Issue:8

    Topics: Aged; Antiemetics; Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Carcinoma, Hepato

1998
Double-blind, multicenter trial to compare the efficacy of intramuscular dihydroergotamine plus hydroxyzine versus intramuscular meperidine plus hydroxyzine for the emergency department treatment of acute migraine headache.
    Annals of emergency medicine, 1998, Volume: 32, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Antiemetics; Dihydro

1998
Double-blind evaluation of hydroxyzine as an antiemetic in pregancy.
    The Journal of reproductive medicine, 1971, Volume: 7, Issue:1

    Topics: Antiemetics; Clinical Trials as Topic; Female; Humans; Hydroxyzine; Hyperemesis Gravidarum; Nausea;

1971

Other Studies

7 other studies available for hydroxyzine and Nausea

ArticleYear
Oral Sedation Postdischarge Adverse Events in Pediatric Dental Patients.
    Anesthesia progress, 2015,Fall, Volume: 62, Issue:3

    Topics: Administration, Oral; Analgesics, Opioid; Anesthesia, Dental; Anesthetics, Inhalation; Child; Child

2015
Intravenous hydroxyzine for postoperative nausea and vomiting.
    Rocky Mountain medical journal, 1960, Volume: 57

    Topics: Humans; Hydroxyzine; Nausea; Postoperative Nausea and Vomiting; Surgical Procedures, Operative; Vomi

1960
NAUSEA AND VOMITING IN PREGNANCY.
    Southwestern medicine, 1964, Volume: 45

    Topics: Female; Humans; Hydroxyzine; Nausea; Pregnancy; Pregnancy Complications; Prochlorperazine; Toxicolog

1964
A new series of oral medications for chronic (cancer) pain relief.
    Comprehensive therapy, 1984, Volume: 10, Issue:5

    Topics: Administration, Oral; Aluminum Hydroxide; Analgesics, Opioid; Antacids; Antiemetics; Cimetidine; Coc

1984
[Hydroxyzine in anesthesia in neurosurgical intervention].
    Zentralblatt fur Neurochirurgie, 1970, Volume: 31, Issue:3

    Topics: Adolescent; Adult; Aged; Blood Circulation; Cardiac Complexes, Premature; Child; Female; Humans; Hyd

1970
Letter: Preabortion medication.
    JAMA, 1974, Feb-04, Volume: 227, Issue:5

    Topics: Abortion, Therapeutic; Anesthesia, General; Diazepam; Female; Humans; Hydroxyzine; Nausea; Pregnancy

1974
[A clinical comparison between 3 varieties of neuroleptic anesthesia].
    Lakartidningen, 1973, Apr-18, Volume: 70, Issue:16

    Topics: Anesthesia, Intravenous; Benperidol; Blood Pressure; Diazepam; Female; Fentanyl; Humans; Hydroxyzine

1973