Page last updated: 2024-10-28

hydroxyzine and Migraine Disorders

hydroxyzine has been researched along with Migraine Disorders in 5 studies

Hydroxyzine: A histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.
hydroxyzine : A N-alkylpiperazine that is piperzine in which the nitrogens atoms are substituted by 2-(2-hydroxyethoxy)ethyl and (4-chlorophenyl)(phenyl)methyl groups respectively.

Migraine Disorders: A class of disabling primary headache disorders, characterized by recurrent unilateral pulsatile headaches. The two major subtypes are common migraine (without aura) and classic migraine (with aura or neurological symptoms). (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)

Research Excerpts

ExcerptRelevanceReference
" The anti-nauseant hydroxyzine (H) was coadministered in both treatment groups."5.08Double-blind, multicenter trial to compare the efficacy of intramuscular dihydroergotamine plus hydroxyzine versus intramuscular meperidine plus hydroxyzine for the emergency department treatment of acute migraine headache. ( Barton, CW; Carleton, SC; Chelly, JE; Chudnofsky, CR; Johnson, G; Morris, DL; Pietrzak, MP; Rhee, KJ; Rosenberg, J; Shesser, RF; Starkman, S; Van Valen, MK, 1998)
"Chronic migraine management almost always requires daily oral preventative medication with potential adverse effects."2.71Observations of the "carry-over effect" following successful termination of chronic migraine in the adolescent with short-term dihydroergotamine, dexamethasone and hydroxyzine: a pilot study. ( Charles, JA; Jotkowitz, S, 2005)
"Forty-seven adult patients with migraines enrolled on 50 visits."2.67Ketorolac versus meperidine and hydroxyzine in the treatment of acute migraine headache: a randomized, prospective, double-blind trial. ( Aldag, J; Duarte, C; Dunaway, F; Frederick, R; Turner, L, 1992)
"Abdominal migraine without headache can be seen in older adults as a migraine equivalent, just as it can occur in children."2.49Managing migraine and other headache syndromes in those over 50. ( Coleman-Jackson, R; Dees, B; Hershey, LA, 2013)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's2 (40.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dees, B1
Coleman-Jackson, R1
Hershey, LA1
Charles, JA1
Jotkowitz, S1
Carleton, SC1
Shesser, RF1
Pietrzak, MP1
Chudnofsky, CR1
Starkman, S1
Morris, DL1
Johnson, G1
Rhee, KJ1
Barton, CW1
Chelly, JE1
Rosenberg, J1
Van Valen, MK1
Duarte, C1
Dunaway, F1
Turner, L1
Aldag, J1
Frederick, R1
Hertrich, O1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
IM Ketorolac vs Diclofenac Potassium Powder for Oral Solution (Cambia) for the Acute Treatment of Severe Migraine[NCT02664116]Phase 440 participants (Anticipated)Interventional2016-01-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for hydroxyzine and Migraine Disorders

ArticleYear
Managing migraine and other headache syndromes in those over 50.
    Maturitas, 2013, Volume: 76, Issue:3

    Topics: Aged; Headache Disorders; Humans; Hydroxyzine; Middle Aged; Migraine Disorders; Naproxen

2013

Trials

3 trials available for hydroxyzine and Migraine Disorders

ArticleYear
Observations of the "carry-over effect" following successful termination of chronic migraine in the adolescent with short-term dihydroergotamine, dexamethasone and hydroxyzine: a pilot study.
    The journal of headache and pain, 2005, Volume: 6, Issue:1

    Topics: Administration, Oral; Adolescent; Adult; Age Factors; Anti-Inflammatory Agents; Brain; Chronic Disea

2005
Double-blind, multicenter trial to compare the efficacy of intramuscular dihydroergotamine plus hydroxyzine versus intramuscular meperidine plus hydroxyzine for the emergency department treatment of acute migraine headache.
    Annals of emergency medicine, 1998, Volume: 32, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Antiemetics; Dihydro

1998
Ketorolac versus meperidine and hydroxyzine in the treatment of acute migraine headache: a randomized, prospective, double-blind trial.
    Annals of emergency medicine, 1992, Volume: 21, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Analgesics; Double-Blind Method; Drug Combinations; Female; Humans

1992

Other Studies

1 other study available for hydroxyzine and Migraine Disorders

ArticleYear
[Neuroleptics, thymoleptics and tranquilizers in neurological therapy].
    Bibliotheca psychiatrica et neurologica, 1969, Volume: 139

    Topics: Basal Ganglia Diseases; Chlordiazepoxide; Chlorpromazine; Diazepam; Epilepsy; Extrapyramidal Tracts;

1969