hydroxyzine has been researched along with Mastocytosis in 5 studies
Hydroxyzine: A histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.
hydroxyzine : A N-alkylpiperazine that is piperzine in which the nitrogens atoms are substituted by 2-(2-hydroxyethoxy)ethyl and (4-chlorophenyl)(phenyl)methyl groups respectively.
Mastocytosis: A rare neoplastic disorder characterized by a clonal proliferation of MAST CELLS, associated with KIT-D816 mutations, and accompanied by aberrant mast cell activation. The abnormal increase of MAST CELLS may occur in only the skin (MASTOCYTOSIS, CUTANEOUS), in extracutaneous tissues involving multiple organs (MASTOCYTOSIS, SYSTEMIC), or in solid tumors (MASTOCYTOMA).
| Excerpt | Relevance | Reference |
|---|---|---|
| "To asses the efficacy of ketotifen (Zaditen; Sandoz Pharmaceuticals, Basel, Switzerland) for the treatment of pediatric mastocytosis, eight children who exhibited symptoms as a result of mastocytosis were enrolled in a 12-week, double-blind, placebo-controlled, crossover trial of ketotifen versus hydroxyzine (Atarax; Roerig, New York, N." | 9.06 | A double-blind, placebo-controlled, crossover trial of ketotifen versus hydroxyzine in the treatment of pediatric mastocytosis. ( Berkebile, C; Bradley, D; Kettelhut, BV; Metcalfe, DD, 1989) |
| "To asses the efficacy of ketotifen (Zaditen; Sandoz Pharmaceuticals, Basel, Switzerland) for the treatment of pediatric mastocytosis, eight children who exhibited symptoms as a result of mastocytosis were enrolled in a 12-week, double-blind, placebo-controlled, crossover trial of ketotifen versus hydroxyzine (Atarax; Roerig, New York, N." | 5.06 | A double-blind, placebo-controlled, crossover trial of ketotifen versus hydroxyzine in the treatment of pediatric mastocytosis. ( Berkebile, C; Bradley, D; Kettelhut, BV; Metcalfe, DD, 1989) |
| "In the cyclosporin-A- and prednisolone-treated groups, mastocytosis was suppressed, but worm expulsion was only slightly delayed, without statistical significance." | 1.32 | Effects of anti-allergic drugs on intestinal mastocytosis and worm expulsion of rats infected with Neodiplostomum seoulense. ( Chai, JY; Guk, SM; Hong, SJ; Kim, TH; Park, JH; Shin, EH, 2003) |
| "Mastocytosis has a highly variable clinical expression, and systemic mastocytosis is occasionally associated with a myeloproliferative or a myelodysplastic disorder." | 1.31 | [Systemic mastocytosis]. ( Dotan, I; Levo, Y; Sade, K, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Swali, R | 1 |
| Wiggins, C | 1 |
| Tyring, SK | 1 |
| Shin, EH | 1 |
| Kim, TH | 1 |
| Hong, SJ | 1 |
| Park, JH | 1 |
| Guk, SM | 1 |
| Chai, JY | 1 |
| Sade, K | 1 |
| Dotan, I | 1 |
| Levo, Y | 1 |
| Raucoules, M | 1 |
| Occelli, G | 1 |
| Grimaud, D | 1 |
| Kettelhut, BV | 1 |
| Berkebile, C | 1 |
| Bradley, D | 1 |
| Metcalfe, DD | 1 |
1 trial available for hydroxyzine and Mastocytosis
| Article | Year |
|---|---|
A double-blind, placebo-controlled, crossover trial of ketotifen versus hydroxyzine in the treatment of pediatric mastocytosis.
Topics: Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Female; Histamine; Humans; H | 1989 |
4 other studies available for hydroxyzine and Mastocytosis
| Article | Year |
|---|---|
A Diffuse Papular Rash in an Adult.
Topics: Adult; Anti-Inflammatory Agents; Desoximetasone; Female; Humans; Hydroxyzine; Mastocytosis | 2020 |
Effects of anti-allergic drugs on intestinal mastocytosis and worm expulsion of rats infected with Neodiplostomum seoulense.
Topics: Animals; Cimetidine; Cyclosporine; Histamine H1 Antagonists; Histamine H2 Antagonists; Hydroxyzine; | 2003 |
[Systemic mastocytosis].
Topics: Aged; Drug Therapy, Combination; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Hydroxy | 2000 |
[Peroperative blood histamine and mastocytosis].
Topics: Adult; Histamine; Humans; Hydroxyzine; Intraoperative Period; Male; Mastocytosis | 1991 |