hydroxyzine has been researched along with Mast Cell Activation Disease in 5 studies
Hydroxyzine: A histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.
hydroxyzine : A N-alkylpiperazine that is piperzine in which the nitrogens atoms are substituted by 2-(2-hydroxyethoxy)ethyl and (4-chlorophenyl)(phenyl)methyl groups respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To asses the efficacy of ketotifen (Zaditen; Sandoz Pharmaceuticals, Basel, Switzerland) for the treatment of pediatric mastocytosis, eight children who exhibited symptoms as a result of mastocytosis were enrolled in a 12-week, double-blind, placebo-controlled, crossover trial of ketotifen versus hydroxyzine (Atarax; Roerig, New York, N." | 9.06 | A double-blind, placebo-controlled, crossover trial of ketotifen versus hydroxyzine in the treatment of pediatric mastocytosis. ( Berkebile, C; Bradley, D; Kettelhut, BV; Metcalfe, DD, 1989) |
| "To asses the efficacy of ketotifen (Zaditen; Sandoz Pharmaceuticals, Basel, Switzerland) for the treatment of pediatric mastocytosis, eight children who exhibited symptoms as a result of mastocytosis were enrolled in a 12-week, double-blind, placebo-controlled, crossover trial of ketotifen versus hydroxyzine (Atarax; Roerig, New York, N." | 5.06 | A double-blind, placebo-controlled, crossover trial of ketotifen versus hydroxyzine in the treatment of pediatric mastocytosis. ( Berkebile, C; Bradley, D; Kettelhut, BV; Metcalfe, DD, 1989) |
| "In the cyclosporin-A- and prednisolone-treated groups, mastocytosis was suppressed, but worm expulsion was only slightly delayed, without statistical significance." | 1.32 | Effects of anti-allergic drugs on intestinal mastocytosis and worm expulsion of rats infected with Neodiplostomum seoulense. ( Chai, JY; Guk, SM; Hong, SJ; Kim, TH; Park, JH; Shin, EH, 2003) |
| "Mastocytosis has a highly variable clinical expression, and systemic mastocytosis is occasionally associated with a myeloproliferative or a myelodysplastic disorder." | 1.31 | [Systemic mastocytosis]. ( Dotan, I; Levo, Y; Sade, K, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Swali, R | 1 |
| Wiggins, C | 1 |
| Tyring, SK | 1 |
| Shin, EH | 1 |
| Kim, TH | 1 |
| Hong, SJ | 1 |
| Park, JH | 1 |
| Guk, SM | 1 |
| Chai, JY | 1 |
| Sade, K | 1 |
| Dotan, I | 1 |
| Levo, Y | 1 |
| Raucoules, M | 1 |
| Occelli, G | 1 |
| Grimaud, D | 1 |
| Kettelhut, BV | 1 |
| Berkebile, C | 1 |
| Bradley, D | 1 |
| Metcalfe, DD | 1 |
1 trial available for hydroxyzine and Mast Cell Activation Disease
| Article | Year |
|---|---|
A double-blind, placebo-controlled, crossover trial of ketotifen versus hydroxyzine in the treatment of pediatric mastocytosis.
Topics: Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Female; Histamine; Humans; H | 1989 |
4 other studies available for hydroxyzine and Mast Cell Activation Disease
| Article | Year |
|---|---|
A Diffuse Papular Rash in an Adult.
Topics: Adult; Anti-Inflammatory Agents; Desoximetasone; Female; Humans; Hydroxyzine; Mastocytosis | 2020 |
Effects of anti-allergic drugs on intestinal mastocytosis and worm expulsion of rats infected with Neodiplostomum seoulense.
Topics: Animals; Cimetidine; Cyclosporine; Histamine H1 Antagonists; Histamine H2 Antagonists; Hydroxyzine; | 2003 |
[Systemic mastocytosis].
Topics: Aged; Drug Therapy, Combination; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Hydroxy | 2000 |
[Peroperative blood histamine and mastocytosis].
Topics: Adult; Histamine; Humans; Hydroxyzine; Intraoperative Period; Male; Mastocytosis | 1991 |