hydroxyzine has been researched along with Infection, Toxoplasma gondii in 3 studies
Hydroxyzine: A histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.
hydroxyzine : A N-alkylpiperazine that is piperzine in which the nitrogens atoms are substituted by 2-(2-hydroxyethoxy)ethyl and (4-chlorophenyl)(phenyl)methyl groups respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Current treatment for toxoplasmosis commonly have high cytotoxic side effects on host and require long durations ranging from one week to more than one year." | 2.61 | Recent progress on anti-Toxoplasma drugs discovery: Design, synthesis and screening. ( Deng, Y; Li, CH; Wu, T; Zhai, SQ, 2019) |
| "gondii tissue cysts in vitro and in vivo." | 2.58 | Activities of anti-Toxoplasma drugs and compounds against tissue cysts in the last three decades (1987 to 2017), a systematic review. ( Daryani, A; Mehrzadi, S; Montazeri, M; Sarvi, S; Shahdin, S; Sharif, M, 2018) |
| "Drug treatment for toxoplasmosis is problematic, because current drugs cannot eradicate latent infection with Toxoplasma gondii and can cause bone marrow toxicity." | 1.46 | Identification of compounds that suppress Toxoplasma gondii tachyzoites and bradyzoites. ( Kato, K; Murata, Y; Sugi, T; Weiss, LM, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Deng, Y | 1 |
| Wu, T | 1 |
| Zhai, SQ | 1 |
| Li, CH | 1 |
| Murata, Y | 1 |
| Sugi, T | 1 |
| Weiss, LM | 1 |
| Kato, K | 1 |
| Montazeri, M | 1 |
| Mehrzadi, S | 1 |
| Sharif, M | 1 |
| Sarvi, S | 1 |
| Shahdin, S | 1 |
| Daryani, A | 1 |
2 reviews available for hydroxyzine and Infection, Toxoplasma gondii
| Article | Year |
|---|---|
Recent progress on anti-Toxoplasma drugs discovery: Design, synthesis and screening.
Topics: Animals; Antiprotozoal Agents; Drug Discovery; Female; Humans; Pregnancy; Toxoplasma; Toxoplasmosis | 2019 |
Activities of anti-Toxoplasma drugs and compounds against tissue cysts in the last three decades (1987 to 2017), a systematic review.
Topics: Abietanes; Animals; Antiparasitic Agents; Atovaquone; Azithromycin; Brain; Cysts; Humans; Hydroxyzin | 2018 |
1 other study available for hydroxyzine and Infection, Toxoplasma gondii
| Article | Year |
|---|---|
Identification of compounds that suppress Toxoplasma gondii tachyzoites and bradyzoites.
Topics: Abietanes; Animals; Antiprotozoal Agents; Cell Line; Chlorocebus aethiops; Host-Parasite Interaction | 2017 |