hydroxyzine has been researched along with Hypersensitivity in 21 studies
Hydroxyzine: A histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.
hydroxyzine : A N-alkylpiperazine that is piperzine in which the nitrogens atoms are substituted by 2-(2-hydroxyethoxy)ethyl and (4-chlorophenyl)(phenyl)methyl groups respectively.
Hypersensitivity: Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen.
| Excerpt | Relevance | Reference |
|---|---|---|
| "One hundred twenty women were followed after exposure to either hydroxyzine or cetirizine during pregnancy." | 7.69 | Prospective controlled study of hydroxyzine and cetirizine in pregnancy. ( Bailey, B; Baillie, M; Einarson, A; Jung, G; Koren, G; Spizzirri, D, 1997) |
| "Cetirizine is a selective H1 antagonist that inhibits the eosinophil recruitment induced by allergen in the skin." | 6.67 | Inhibitory effect of cetirizine on the bronchial eosinophil recruitment induced by allergen inhalation challenge in allergic patients with asthma. ( Chanez, P; Clauzel, AM; De Vos, C; Godard, P; Michel, FB; Rédier, H; Rifaï, N, 1992) |
| " One of these, cetirizine, a human metabolite of hydroxyzine, is characterized by its high selectivity for the H1 receptor site and its reliable and consistent inhibition of histamine-induced allergic reactions." | 4.78 | Cetirizine: antiallergic therapy beyond traditional H1 antihistamines. ( Samuels, LL; Sheffer, AL, 1990) |
| " and intracerebroventricular pentobarbital-induced sedation and alcohol-induced ataxia models." | 3.76 | Characterization of anti-inflammatory properties and evidence for no sedation liability for the novel antihistamine SUN-1334H. ( Bagad, AS; Bahekar, PC; Chidrewar, GU; Mandhane, SN; Mehetre, SV; Pawar, CA; Rajamannar, T; Rao, CT; Shah, JH, 2010) |
| "One hundred twenty women were followed after exposure to either hydroxyzine or cetirizine during pregnancy." | 3.69 | Prospective controlled study of hydroxyzine and cetirizine in pregnancy. ( Bailey, B; Baillie, M; Einarson, A; Jung, G; Koren, G; Spizzirri, D, 1997) |
| "Cetirizine is a selective H1 antagonist that inhibits the eosinophil recruitment induced by allergen in the skin." | 2.67 | Inhibitory effect of cetirizine on the bronchial eosinophil recruitment induced by allergen inhalation challenge in allergic patients with asthma. ( Chanez, P; Clauzel, AM; De Vos, C; Godard, P; Michel, FB; Rédier, H; Rifaï, N, 1992) |
| "With cetirizine, there was also a reduction in the levels of LTC4 (not measured in terfenadine studies) but not in those of recovered histamine and prostaglandin D2." | 2.66 | The effects of H1 antihistamines on the early allergic response. ( Baroody, F; Freidhoff, L; Kagey-Sobotka, A; Lichtenstein, LM; Naclerio, RM; Norman, PS; Proud, D, 1989) |
| "Cetirizine is a new anti-allergic compound with a potent, long-acting, and specific antihistaminic property." | 1.28 | Inhibition of human eosinophil chemotaxis and of the IgE-dependent stimulation of human blood platelets by cetirizine. ( Capron, A; Capron, M; De Vos, C; Joseph, M; Leprevost, C; Tomassini, M; Vorng, H, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (47.62) | 18.7374 |
| 1990's | 9 (42.86) | 18.2507 |
| 2000's | 1 (4.76) | 29.6817 |
| 2010's | 1 (4.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mandhane, SN | 1 |
| Shah, JH | 1 |
| Bahekar, PC | 1 |
| Mehetre, SV | 1 |
| Pawar, CA | 1 |
| Bagad, AS | 1 |
| Chidrewar, GU | 1 |
| Rao, CT | 1 |
| Rajamannar, T | 1 |
| ARBESMAN, CE | 1 |
| EHRENREICH, RJ | 1 |
| RICHERI, OR | 1 |
| ORCIUOLI, L | 1 |
| GRATER, WC | 1 |
| SANTOS, IM | 1 |
| UNGER, L | 1 |
| Elzainy, AA | 1 |
| Gu, X | 1 |
| Simons, FE | 1 |
| Simons, KJ | 1 |
| Barlow, PP | 1 |
| Burger, JH | 1 |
| Einarson, A | 1 |
| Bailey, B | 1 |
| Jung, G | 1 |
| Spizzirri, D | 1 |
| Baillie, M | 1 |
| Koren, G | 1 |
| Turner, TW | 1 |
| Gale, AE | 1 |
| Townley, RG | 1 |
| Okada, C | 1 |
| Ollier, S | 1 |
| Rédier, H | 1 |
| Chanez, P | 1 |
| De Vos, C | 3 |
| Rifaï, N | 1 |
| Clauzel, AM | 1 |
| Michel, FB | 1 |
| Godard, P | 1 |
| Ryhal, BT | 1 |
| Fletcher, MP | 1 |
| Rivest, J | 1 |
| Despontin, K | 1 |
| Ghys, L | 1 |
| Rihoux, JP | 1 |
| Lachapelle, JM | 1 |
| Bernheim, J | 1 |
| Arendt, C | 1 |
| Gleich, GJ | 1 |
| Sheffer, AL | 1 |
| Samuels, LL | 1 |
| Joseph, M | 1 |
| Leprevost, C | 1 |
| Vorng, H | 1 |
| Tomassini, M | 1 |
| Capron, M | 1 |
| Capron, A | 1 |
| Goetz, DW | 1 |
| Jacobson, JM | 1 |
| Murnane, JE | 1 |
| Reid, MJ | 1 |
| Repperger, DW | 1 |
| Goodyear, C | 1 |
| Martin, ME | 1 |
| Baroody, F | 1 |
| Proud, D | 1 |
| Kagey-Sobotka, A | 1 |
| Freidhoff, L | 1 |
| Norman, PS | 1 |
| Lichtenstein, LM | 1 |
| Naclerio, RM | 1 |
| Grolnick, M | 1 |
4 reviews available for hydroxyzine and Hypersensitivity
| Article | Year |
|---|---|
Use of cetirizine to investigate non-H1 effects of second-generation antihistamines.
Topics: Cetirizine; Histamine Antagonists; Histamine H1 Antagonists; Humans; Hydroxyzine; Hypersensitivity; | 1992 |
The second-generation antihistamines. What makes them different?
Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Blood-Brain Barrier; Brain; Cetirizine; Cyprohepta | 1991 |
Cetirizine: more than an antihistamine?
Topics: Allergens; Animals; Asthma; Cetirizine; Exercise; Histamine Antagonists; Histamine H1 Antagonists; H | 1991 |
Cetirizine: antiallergic therapy beyond traditional H1 antihistamines.
Topics: Cetirizine; Diphenhydramine; Histamine H1 Antagonists; Humans; Hydroxyzine; Hypersensitivity; Reacti | 1990 |
4 trials available for hydroxyzine and Hypersensitivity
| Article | Year |
|---|---|
Inhibitory effect of cetirizine on the bronchial eosinophil recruitment induced by allergen inhalation challenge in allergic patients with asthma.
Topics: Administration, Inhalation; Adult; Allergens; Asthma; Bronchi; Bronchial Provocation Tests; Bronchoa | 1992 |
Pharmacological modulation by cetirizine and ebastine of the cutaneous reactivity to histamine.
Topics: Administration, Cutaneous; Administration, Oral; Adult; Butyrophenones; Capsules; Cetirizine; Double | 1991 |
Prolongation of simple and choice reaction times in a double-blind comparison of twice-daily hydroxyzine versus terfenadine.
Topics: Adult; Benzhydryl Compounds; Central Nervous System; Decision Making; Double-Blind Method; Female; H | 1989 |
The effects of H1 antihistamines on the early allergic response.
Topics: Benzhydryl Compounds; Calcium Channels; Cetirizine; Dopamine; Histamine H1 Antagonists; Humans; Hydr | 1989 |
13 other studies available for hydroxyzine and Hypersensitivity
| Article | Year |
|---|---|
Characterization of anti-inflammatory properties and evidence for no sedation liability for the novel antihistamine SUN-1334H.
Topics: Acetates; Alcohols; Anaphylaxis; Animals; Anti-Inflammatory Agents, Non-Steroidal; Ataxia; Cetirizin | 2010 |
Prednisolone alone and in combination with hydroxyzine; a comparative study in allergic disorders.
Topics: Hydroxyzine; Hypersensitivity; Immune System Diseases; Prednisolone; Tranquilizing Agents | 1958 |
[Hydroxyzine in the treatment of allergic disorders: preliminary report].
Topics: Hydroxyzine; Hypersensitivity; Immune System Diseases; Tranquilizing Agents | 1958 |
Vistaril in allergy.
Topics: Humans; Hydroxyzine; Hypersensitivity | 1960 |
Hydroxyzine (atarax) in allergic diseases.
Topics: Humans; Hydroxyzine; Hypersensitivity; Immune System Diseases | 1960 |
Hydroxyzine from topical phospholipid liposomal formulations: evaluation of peripheral antihistaminic activity and systemic absorption in a rabbit model.
Topics: Animals; Chemistry, Pharmaceutical; Disease Models, Animal; Drug Delivery Systems; Histamine; Histam | 2003 |
A combined drug for asthmatic symptoms.
Topics: Adolescent; Adult; Aged; Asthma; Child; Chronic Disease; Ephedrine; Female; Humans; Hydroxyzine; Hyp | 1967 |
Prospective controlled study of hydroxyzine and cetirizine in pregnancy.
Topics: Abortion, Spontaneous; Abortion, Therapeutic; Alcohol Drinking; Anti-Allergic Agents; Birth Rate; Bi | 1997 |
Urticaria.
Topics: Anti-Anxiety Agents; Attitude of Health Personnel; Dermatologic Agents; Dermatology; Food Hypersensi | 1978 |
Cutaneous responses--a window on inflammatory processes.
Topics: Cetirizine; Histamine H1 Antagonists; Humans; Hydroxyzine; Hypersensitivity; Inflammation; Skin | 1992 |
Why do allergic individuals accumulate more eosinophils at the site of an IgE-mediated reaction than do normal subjects?
Topics: Cetirizine; Eosinophils; Histamine H1 Antagonists; Humans; Hydroxyzine; Hypersensitivity; Immunoglob | 1990 |
Inhibition of human eosinophil chemotaxis and of the IgE-dependent stimulation of human blood platelets by cetirizine.
Topics: Blood Platelets; Cetirizine; Chemotaxis, Leukocyte; Chlorpheniramine; Cytotoxicity, Immunologic; Eos | 1989 |
An investigative and clinical evaluation of dermographism.
Topics: Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Dermatitis, Atopic; Edema; Erythema; | 1970 |