hydroxyzine has been researched along with Hives in 94 studies
Hydroxyzine: A histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.
hydroxyzine : A N-alkylpiperazine that is piperzine in which the nitrogens atoms are substituted by 2-(2-hydroxyethoxy)ethyl and (4-chlorophenyl)(phenyl)methyl groups respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the efficacy of a 4-day "burst" course of prednisone added to standard treatment with H1 antihistamines for the management of acute urticaria in outpatients." | 9.08 | Outpatient management of acute urticaria: the role of prednisone. ( Pollack, CV; Romano, TJ, 1995) |
| "In a randomized, double-blind, parallel-group study in 16 patients with chronic urticaria, we investigated the pharmacokinetics and suppressive effect on the histamine-induced wheal and flare of a single dose of hydroxyzine 25 mg or cetirizine 10 mg, given before and after treatment with cimetidine 600 mg every 12 hours for 10 days." | 9.08 | Effect of the H2-antagonist cimetidine on the pharmacokinetics and pharmacodynamics of the H1-antagonists hydroxyzine and cetirizine in patients with chronic urticaria. ( Simons, FE; Simons, KJ; Sussman, GL, 1995) |
| "To compare the safety and efficacy of cetirizine with that of hydroxyzine and placebo in the treatment of chronic idiopathic urticaria." | 9.08 | Cetirizine versus hydroxyzine and placebo in chronic idiopathic urticaria. ( Breneman, DL, 1996) |
| "Cetirizine, a peripheral H1 antagonist, was administered to patients with delayed pressure urticaria in a double-blind, placebo-controlled, crossover study." | 9.07 | Therapeutic effects of cetirizine in delayed pressure urticaria: clinicopathologic findings. ( Aroni, K; Demaka, P; Gonianakis, M; Kontou-Fili, K; Maniatakou, G; Palaiologos, G, 1991) |
| "The efficacy of cetirizine dihydrochloride, a new H1-antagonist claimed to have minimal sedative property was evaluated in 28 patients with chronic idiopathic urticaria." | 9.07 | Cetirizine vs placebo in chronic idiopathic urticaria--a double blind randomised cross-over study. ( Goh, CL; Lim, J; Wong, WK, 1991) |
| "The efficacy of cetirizine dihydrochloride, a new H1-antagonist with minimal sedative or anticholinergic side effects was evaluated in 30 patients with chronic idiopathic urticaria." | 9.06 | Treatment of chronic urticaria with cetirizine dihydrochloride a non-sedating antihistamine. ( Arendt, C; Juhlin, L, 1988) |
| "A total of 21 patients with a diagnosis of chronic idiopathic urticaria were assessed in a fully randomized, double-blind, crossover study to investigate the efficacy of 8 mg acrivastine versus 20 mg hydroxyzine and placebo administered three times daily." | 9.06 | A comparison of acrivastine versus hydroxyzine and placebo in the treatment of chronic idiopathic urticaria. ( Calthrop, JG; Gibson, JR; Harvey, SG; Salo, OP, 1989) |
| "Results of a double-blind, randomized, placebo-controlled, parallel study in 37 patients indicate that terfenadine, 60 mg bid, is significantly more effective than placebo and as effective as hydroxyzine, 25 mg qid, in the treatment of chronic idiopathic urticaria without causing the somnolence that was associated with the use of hydroxyzine." | 9.06 | Double-blind, placebo-controlled study of terfenadine and hydroxyzine in patients with chronic idiopathic urticaria. ( Ball, R; Boggs, PB; Ellis, CN; Grossman, J; Gupta, AK; Shulan, D; Washburne, WF, 1989) |
| "Randomized double-blind trials using doxepin and several conventional antihistamines were carried out for treatment of patients with idiopathic cold urticaria." | 9.05 | Comparison of cinnarizine, cyproheptadine, doxepin, and hydroxyzine in treatment of idiopathic cold urticaria: usefulness of doxepin. ( Fräki, JE; Myöhänen, T; Neittaanmäki, H, 1984) |
| "We report a case of acute urticaria probably caused by hydroxyzine hydrochloride." | 7.70 | [A case of acute urticaria from hydroxyzine hydrochloride used for preanesthetic medication]. ( Fujii, K; Kitajima, T; Okuda, Y; Tezuka, M; Urabe, K; Yamakage, A; Yamazaki, T, 2000) |
| "Three patients with chronic urticaria, two of whom also had angioedema, were treated with oral cyclosporine, 6 mg/kg per day." | 7.68 | Oral cyclosporine for severe chronic idiopathic urticaria and angioedema. ( Ellis, CN; Fradin, MS; Goldfarb, MT; Voorhees, JJ, 1991) |
| "The effects of oral administration of the antihistamine cetirizine on the weal and flare caused by intradermal injection of platelet activating factor (PAF-acether), kallikrein, histamine and the patient's own serum were investigated in 10 patients with chronic urticaria." | 7.68 | Effect of cetirizine on cutaneous reactions to PAF, kallikrein and serum in patients with chronic urticaria. ( Juhlin, L; Rihoux, JP, 1990) |
| " At the dosage used, cetirizine therapy appears to be no more effective than terfenadine." | 6.67 | A comparison of cetirizine and terfenadine in the management of solar urticaria. ( Bilsland, D; Ferguson, J, 1991) |
| "Loratadine was safe and well tolerated with sedation and dry mouth similar to placebo and significantly less than hydroxyzine." | 6.67 | Relative efficacy and safety of loratadine, hydroxyzine, and placebo in chronic idiopathic urticaria. ( Bernstein, DI; Cuss, F; Danzig, MR; Fox, RW; Garvin, PR; Grabiec, SV; Honsinger, RW; Kalivas, JT; Katz, HI; Monroe, EW, 1992) |
| "Chronic urticaria is a problem for both physician and patient." | 6.67 | Urticaria: clinical efficacy of cetirizine in comparison with hydroxyzine and placebo. ( Bigby, M; Breneman, D; Bruce, S; Kalivas, J; Tharp, M, 1990) |
| "Cetirizine is a new H1 antagonist with potent inhibitory action against the infiltration of eosinophils into involved tissue, thereby affecting the late-phase reaction." | 6.38 | Cetirizine: a new H1 antagonist with antieosinophilic activity in chronic urticaria. ( Townley, RG, 1991) |
| "To test this belief by comparing the effectiveness and prevalence of unwanted sedative effects when treating patients with chronic spontaneous urticaria (CSU) with levocetirizine 15 mg daily plus hydroxyzine 50 mg at night (levocetirizine plus hydroxyzine) vs." | 5.19 | Night-time sedating H1 -antihistamine increases daytime somnolence but not treatment efficacy in chronic spontaneous urticaria: a randomized controlled trial. ( Church, MK; Dimitrov, V; Gugutkova, M; Kralimarkova, T; Lazarova, C; Popov, TA; Staevska, M; Zuberbier, T, 2014) |
| "Nonsedating antihistamines (nsAHs) are recommended as first-line therapeutics for the treatment of mast cell-driven disorders, including allergic rhinitis and urticaria." | 5.14 | Suppression of histamine- and allergen-induced skin reactions: comparison of first- and second-generation antihistamines. ( dos Santos, RV; Lima, HC; Magerl, M; Mlynek, A, 2009) |
| "To evaluate the efficacy of a 4-day "burst" course of prednisone added to standard treatment with H1 antihistamines for the management of acute urticaria in outpatients." | 5.08 | Outpatient management of acute urticaria: the role of prednisone. ( Pollack, CV; Romano, TJ, 1995) |
| "In a randomized, double-blind, parallel-group study in 16 patients with chronic urticaria, we investigated the pharmacokinetics and suppressive effect on the histamine-induced wheal and flare of a single dose of hydroxyzine 25 mg or cetirizine 10 mg, given before and after treatment with cimetidine 600 mg every 12 hours for 10 days." | 5.08 | Effect of the H2-antagonist cimetidine on the pharmacokinetics and pharmacodynamics of the H1-antagonists hydroxyzine and cetirizine in patients with chronic urticaria. ( Simons, FE; Simons, KJ; Sussman, GL, 1995) |
| "To compare the safety and efficacy of cetirizine with that of hydroxyzine and placebo in the treatment of chronic idiopathic urticaria." | 5.08 | Cetirizine versus hydroxyzine and placebo in chronic idiopathic urticaria. ( Breneman, DL, 1996) |
| "The efficacy of astemizole, diphenhydramine, and hydroxyzine hydrochloride in the treatment of chronic idiopathic urticaria was evaluated in this 3-month double-blind, randomized, parallel group study." | 5.07 | Controlled trial of H1 antagonists in the treatment of chronic idiopathic urticaria. ( Jancelewicz, Z; Sussman, G, 1991) |
| "Cetirizine, a peripheral H1 antagonist, was administered to patients with delayed pressure urticaria in a double-blind, placebo-controlled, crossover study." | 5.07 | Therapeutic effects of cetirizine in delayed pressure urticaria: clinicopathologic findings. ( Aroni, K; Demaka, P; Gonianakis, M; Kontou-Fili, K; Maniatakou, G; Palaiologos, G, 1991) |
| "The efficacy of cetirizine dihydrochloride, a new H1-antagonist claimed to have minimal sedative property was evaluated in 28 patients with chronic idiopathic urticaria." | 5.07 | Cetirizine vs placebo in chronic idiopathic urticaria--a double blind randomised cross-over study. ( Goh, CL; Lim, J; Wong, WK, 1991) |
| "A total of 21 patients with a diagnosis of chronic idiopathic urticaria were assessed in a fully randomized, double-blind, crossover study to investigate the efficacy of 8 mg acrivastine versus 20 mg hydroxyzine and placebo administered three times daily." | 5.06 | A comparison of acrivastine versus hydroxyzine and placebo in the treatment of chronic idiopathic urticaria. ( Calthrop, JG; Gibson, JR; Harvey, SG; Salo, OP, 1989) |
| "Results of a double-blind, randomized, placebo-controlled, parallel study in 37 patients indicate that terfenadine, 60 mg bid, is significantly more effective than placebo and as effective as hydroxyzine, 25 mg qid, in the treatment of chronic idiopathic urticaria without causing the somnolence that was associated with the use of hydroxyzine." | 5.06 | Double-blind, placebo-controlled study of terfenadine and hydroxyzine in patients with chronic idiopathic urticaria. ( Ball, R; Boggs, PB; Ellis, CN; Grossman, J; Gupta, AK; Shulan, D; Washburne, WF, 1989) |
| "The efficacy of cetirizine dihydrochloride, a new H1-antagonist with minimal sedative or anticholinergic side effects was evaluated in 30 patients with chronic idiopathic urticaria." | 5.06 | Treatment of chronic urticaria with cetirizine dihydrochloride a non-sedating antihistamine. ( Arendt, C; Juhlin, L, 1988) |
| "Randomized double-blind trials using doxepin and several conventional antihistamines were carried out for treatment of patients with idiopathic cold urticaria." | 5.05 | Comparison of cinnarizine, cyproheptadine, doxepin, and hydroxyzine in treatment of idiopathic cold urticaria: usefulness of doxepin. ( Fräki, JE; Myöhänen, T; Neittaanmäki, H, 1984) |
| "The second-generation H1-receptor antagonists terfenadine, astemizole, loratadine, and cetirizine are important first-line drugs for the relief of symptoms in patients with allergic rhinoconjunctivitis or chronic urticaria and may eventually supplant the potentially sedating first-generation H1-receptor antagonists in the treatment of these disorders." | 4.78 | Recent advances in H1-receptor antagonist treatment. ( Simons, FE, 1990) |
| "Leucocytes from healthy donors were isolated and incubated in varying concentrations of ciclosporin, ascomycin, methotrexate, diphenhydramine or hydroxyzine for 30 min prior to stimulation with serum from urticaria patients known to have functional immunoglobulin (Ig)G antibodies directed against the alpha subunit of the IgE receptor." | 3.73 | Effects of calcineurin inhibitors on an in vitro assay for chronic urticaria. ( Joseph, K; Kaplan, AP; Marsland, AM; Soundararajan, S, 2005) |
| "We report a case of acute urticaria probably caused by hydroxyzine hydrochloride." | 3.70 | [A case of acute urticaria from hydroxyzine hydrochloride used for preanesthetic medication]. ( Fujii, K; Kitajima, T; Okuda, Y; Tezuka, M; Urabe, K; Yamakage, A; Yamazaki, T, 2000) |
| "Three patients with chronic urticaria, two of whom also had angioedema, were treated with oral cyclosporine, 6 mg/kg per day." | 3.68 | Oral cyclosporine for severe chronic idiopathic urticaria and angioedema. ( Ellis, CN; Fradin, MS; Goldfarb, MT; Voorhees, JJ, 1991) |
| "The effects of oral administration of the antihistamine cetirizine on the weal and flare caused by intradermal injection of platelet activating factor (PAF-acether), kallikrein, histamine and the patient's own serum were investigated in 10 patients with chronic urticaria." | 3.68 | Effect of cetirizine on cutaneous reactions to PAF, kallikrein and serum in patients with chronic urticaria. ( Juhlin, L; Rihoux, JP, 1990) |
| "The combination of hydroxyzine and cimetidine is reported to be more effective than hydroxyzine alone in chronic urticaria." | 3.67 | Cimetidine increases the plasma concentration of hydroxyzine. ( Kauppinen, K; Männistö, PT; Salo, OP, 1986) |
| "In a single patient with severe essential acquired cold urticaria, the following drug regimes were assessed: diphenhydramine, cyproheptadine, hydroxyzine, terbutaline, cimetidine, hydroxyzine plus cimetidine, and hydroxyzine plus terbutaline." | 3.66 | Treatment of cold urticaria. ( Highet, AS; Titterington, DM, 1979) |
| "Chronic urticaria is a problem for both physician and patient." | 2.67 | Urticaria: clinical efficacy of cetirizine in comparison with hydroxyzine and placebo. ( Bigby, M; Breneman, D; Bruce, S; Kalivas, J; Tharp, M, 1990) |
| " At the dosage used, cetirizine therapy appears to be no more effective than terfenadine." | 2.67 | A comparison of cetirizine and terfenadine in the management of solar urticaria. ( Bilsland, D; Ferguson, J, 1991) |
| "Treatment with hydroxyzine in patients with CU improved the clinical symptoms and modified the profile of HR; more histamine was recovered at 1 hour (p less than 0." | 2.67 | Effects of H1-antihistamine drug regimen on histamine release by nonlesional skin mast cells of patients with chronic urticaria. ( Bédard, PM; Brunet, C; Hébert, J, 1990) |
| "Loratadine was safe and well tolerated with sedation and dry mouth similar to placebo and significantly less than hydroxyzine." | 2.67 | Relative efficacy and safety of loratadine, hydroxyzine, and placebo in chronic idiopathic urticaria. ( Bernstein, DI; Cuss, F; Danzig, MR; Fox, RW; Garvin, PR; Grabiec, SV; Honsinger, RW; Kalivas, JT; Katz, HI; Monroe, EW, 1992) |
| "Cetirizine was significantly more effective than dexchlorpheniramine in suppressing the size of wheals from 2 to 24 h after drug administration." | 2.66 | Attenuation of cutaneous reactivity to histamine by cetirizine and dexchlorpheniramine. ( Botha, JJ; Groenewoud, G; Luus, HG; Müller, FO; van Dyk, M, 1988) |
| "Chronic urticaria is a frustrating problem for the patient and the physician." | 2.65 | Combined H1 and H2 antihistamine therapy in chronic urticaria. ( Cohen, SH; Kalbfleisch, J; Monroe, EW; Schulz, CI, 1981) |
| "Cetirizine is a new H1 antagonist with potent inhibitory action against the infiltration of eosinophils into involved tissue, thereby affecting the late-phase reaction." | 2.38 | Cetirizine: a new H1 antagonist with antieosinophilic activity in chronic urticaria. ( Townley, RG, 1991) |
| "Aquagenic urticaria is a rare form of physical urticaria characterized by small follicular wheals with an erythematous flare upon exposure to water." | 1.28 | Aquagenic urticaria. ( Crowe, MJ; Guin, JD; Parker, RK, 1992) |
| "There was no evidence of causes for the anaphylactic reactions over a two and a half year period." | 1.27 | Life-threatening idiopathic anaphylaxis associated with hyperimmunoglobulinemia E. ( Greenberger, PA, 1984) |
| "Hydroxyzine is an effective therapy." | 1.27 | Follicular dermographism. ( Shelley, ED; Shelley, WB, 1983) |
| "Histamine was released into the systemic circulation in both conditions in a similar time course; however, systemic symptoms occurred only after the 41 degree C bath." | 1.26 | Evaluation of a patient with both aquagenic and cholinergic urticaria. ( Bock, SA; Davis, RS; Remigio, LK; Schocket, AL, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 48 (51.06) | 18.7374 |
| 1990's | 28 (29.79) | 18.2507 |
| 2000's | 12 (12.77) | 29.6817 |
| 2010's | 5 (5.32) | 24.3611 |
| 2020's | 1 (1.06) | 2.80 |
| Authors | Studies |
|---|---|
| Cook, JS | 1 |
| Angles, A | 1 |
| Morley, E | 1 |
| Staevska, M | 1 |
| Gugutkova, M | 1 |
| Lazarova, C | 1 |
| Kralimarkova, T | 1 |
| Dimitrov, V | 1 |
| Zuberbier, T | 1 |
| Church, MK | 1 |
| Popov, TA | 1 |
| Nath, PI | 1 |
| Coop, CA | 1 |
| Grattan, C | 1 |
| Sharma, M | 1 |
| Bennett, C | 1 |
| Cohen, SN | 1 |
| Carter, B | 1 |
| Kaplan, AP | 5 |
| Joseph, K | 2 |
| Maykut, RJ | 1 |
| Geba, GP | 1 |
| Zeldin, RK | 1 |
| Wan, KS | 1 |
| dos Santos, RV | 1 |
| Magerl, M | 1 |
| Mlynek, A | 1 |
| Lima, HC | 1 |
| do Valle, SO | 1 |
| França, AT | 1 |
| Pires, GV | 1 |
| Guimarães, P | 1 |
| Dias, GA | 1 |
| Levy, SA | 1 |
| Scheindlin, S | 1 |
| ZELCER, I | 1 |
| FEINBERG, AR | 1 |
| PRUZANSKY, JJ | 1 |
| FEINBERG, SM | 1 |
| FISHERMAN, EW | 1 |
| NINOMIYA, S | 1 |
| Marsland, AM | 1 |
| Soundararajan, S | 1 |
| Ujiie, H | 1 |
| Shimizu, T | 1 |
| Natsuga, K | 1 |
| Arita, K | 1 |
| Tomizawa, K | 1 |
| Shimizu, H | 1 |
| Chang, YS | 1 |
| Kwon, HS | 1 |
| Cho, SH | 1 |
| Kim, YY | 1 |
| Min, KU | 1 |
| Kalogeromitros, D | 1 |
| Papageorgiou, C | 1 |
| Gregoriou, S | 1 |
| Chatziantonakis, N | 1 |
| Makris, M | 1 |
| Spanoudaki, N | 1 |
| Rabavilas, A | 1 |
| Rigopoulos, D | 1 |
| Theoharides, TC | 1 |
| Harvey, RP | 2 |
| Schocket, AL | 3 |
| Monroe, EW | 2 |
| Cohen, SH | 1 |
| Kalbfleisch, J | 1 |
| Schulz, CI | 1 |
| Wegs, J | 1 |
| Rantanen, T | 1 |
| Suhonen, R | 1 |
| Garafalo, J | 1 |
| Neittaanmäki, H | 1 |
| Myöhänen, T | 1 |
| Fräki, JE | 1 |
| Shelley, WB | 1 |
| Shelley, ED | 1 |
| Greenberger, PA | 1 |
| Soter, NA | 3 |
| Wasserman, SI | 1 |
| Berman, BA | 1 |
| Ross, RN | 1 |
| Sly, RM | 1 |
| Davis, RS | 1 |
| Remigio, LK | 1 |
| Bock, SA | 1 |
| Pollack, CV | 1 |
| Romano, TJ | 1 |
| Simons, FE | 3 |
| Sussman, GL | 1 |
| Simons, KJ | 2 |
| Breneman, DL | 1 |
| Michel, M | 1 |
| Dompmartin, A | 1 |
| Louvet, S | 1 |
| Szczurko, C | 1 |
| Castel, B | 1 |
| Leroy, D | 1 |
| Demoly, P | 1 |
| Messaad, D | 1 |
| Benahmed, S | 1 |
| Sahla, H | 1 |
| Bousquet, J | 1 |
| Urabe, K | 1 |
| Fujii, K | 1 |
| Tezuka, M | 1 |
| Okuda, Y | 1 |
| Kitajima, T | 1 |
| Yamazaki, T | 1 |
| Yamakage, A | 1 |
| Turner, TW | 1 |
| Gale, AE | 1 |
| Tindall, JP | 1 |
| Nurse, DS | 1 |
| Weisman, BL | 1 |
| Lockey, RF | 1 |
| Highet, AS | 1 |
| Titterington, DM | 1 |
| Czarny, D | 1 |
| Baraf, CS | 1 |
| Gómez, HO | 1 |
| Gómez-Orozco, L | 2 |
| Ortega Gómez, H | 1 |
| Bajorin, DF | 1 |
| Chapman, PB | 1 |
| Wong, GY | 1 |
| Cody, BV | 1 |
| Cordon-Cardo, C | 1 |
| Dantes, L | 1 |
| Templeton, MA | 1 |
| Scheinberg, D | 1 |
| Oettgen, HF | 1 |
| Houghton, AN | 1 |
| Townley, RG | 2 |
| Okada, C | 1 |
| Parker, RK | 1 |
| Crowe, MJ | 1 |
| Guin, JD | 1 |
| Bernstein, DI | 1 |
| Fox, RW | 1 |
| Grabiec, SV | 1 |
| Honsinger, RW | 1 |
| Kalivas, JT | 1 |
| Katz, HI | 1 |
| Cuss, F | 1 |
| Danzig, MR | 1 |
| Garvin, PR | 1 |
| Kontou-Fili, K | 3 |
| Maniatakou, G | 3 |
| Demaka, P | 2 |
| Gonianakis, M | 2 |
| Palaiologos, G | 1 |
| Aroni, K | 2 |
| Goh, CL | 1 |
| Wong, WK | 1 |
| Lim, J | 1 |
| Sussman, G | 1 |
| Jancelewicz, Z | 1 |
| Bilsland, D | 1 |
| Ferguson, J | 1 |
| Brunet, C | 1 |
| Bédard, PM | 1 |
| Hébert, J | 1 |
| Fradin, MS | 1 |
| Ellis, CN | 2 |
| Goldfarb, MT | 1 |
| Voorhees, JJ | 1 |
| Juhlin, L | 4 |
| Rihoux, JP | 4 |
| McMillan, JL | 1 |
| Lobaton, P | 1 |
| Moreno, F | 1 |
| Coulie, P | 1 |
| Kietzmann, H | 1 |
| Macher, E | 1 |
| Ghys, L | 1 |
| Paleologos, G | 2 |
| Kalivas, J | 1 |
| Breneman, D | 1 |
| Tharp, M | 1 |
| Bruce, S | 1 |
| Bigby, M | 1 |
| Campoli-Richards, DM | 1 |
| Buckley, MM | 1 |
| Fitton, A | 1 |
| Salo, OP | 2 |
| Kauppinen, K | 1 |
| Männistö, PT | 1 |
| Kobza Black, A | 1 |
| Aboobaker, J | 1 |
| Gibson, JR | 2 |
| Harvey, SG | 2 |
| Marks, P | 1 |
| Quaranta, JH | 1 |
| Rohr, AS | 1 |
| Rachelefsky, GS | 1 |
| Siegel, SC | 1 |
| Katz, RM | 1 |
| Spector, SL | 1 |
| Mickey, MR | 1 |
| Calthrop, JG | 1 |
| Billardon, M | 1 |
| Boggs, PB | 1 |
| Grossman, J | 1 |
| Washburne, WF | 1 |
| Gupta, AK | 1 |
| Ball, R | 1 |
| Shulan, D | 1 |
| Wagner, W | 1 |
| Rose, MH | 1 |
| Arendt, C | 1 |
| Pechadre, JC | 1 |
| Vernay, D | 1 |
| Trolese, JF | 1 |
| Bloom, M | 1 |
| Dupont, P | 1 |
| Youngchaiyud, U | 1 |
| de Vos, C | 1 |
| Müller, FO | 1 |
| Botha, JJ | 1 |
| van Dyk, M | 1 |
| Luus, HG | 1 |
| Groenewoud, G | 1 |
| Berg, RE | 1 |
| Kantor, GR | 1 |
| Bergfeld, WF | 1 |
| Lembo, G | 1 |
| Raulo, U | 1 |
| Cantelli, V | 1 |
| Patruno, C | 1 |
| Ting, S | 1 |
| Rauls, DO | 1 |
| Ashbaugh, P | 1 |
| Mansfield, LE | 1 |
| Berger, RS | 1 |
| Hyman, A | 1 |
| Prestia, A | 1 |
| Grolnick, M | 1 |
| Moore-Robinson, M | 1 |
| Warin, RP | 1 |
| Bart, RS | 1 |
| Ackerman, AB | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy and Safety of 20 mg Levocetirizine and 15 mg Levocetirizine + 50 mg Bed-Time Hydroxyzine in Severe Chronic Urticaria in Adults: a Pilot, Randomized, Double-blind, Cross-over and Parallel, Active-controlled, Single-centre Study[NCT01250652] | Phase 4 | 24 participants (Actual) | Interventional | 2011-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 reviews available for hydroxyzine and Hives
| Article | Year |
|---|---|
H1-antihistamines for chronic spontaneous urticaria.
Topics: Cetirizine; Cyproheptadine; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Randomized Co | 2014 |
Physical urticaria/angioedema: an experimental model of mast cell activation in humans.
Topics: Angioedema; Body Temperature; Chemotactic Factors; Cyproheptadine; Hot Temperature; Humans; Hydroxyz | 1980 |
Physical urticaria/angioedema as an experimental model of acute and chronic inflammation in human skin.
Topics: Acute Disease; Angioedema; Body Temperature; Chronic Disease; Cold Temperature; Cyproheptadine; Derm | 1981 |
Use of cetirizine to investigate non-H1 effects of second-generation antihistamines.
Topics: Cetirizine; Histamine Antagonists; Histamine H1 Antagonists; Humans; Hydroxyzine; Hypersensitivity; | 1992 |
Cetirizine: a new H1 antagonist with antieosinophilic activity in chronic urticaria.
Topics: Cetirizine; Chronic Disease; Eosinophils; Histamine H1 Antagonists; Humans; Hydroxyzine; Urticaria | 1991 |
Recent advances in H1-receptor antagonist treatment.
Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Cetirizine; Cyproheptadine; Histamine H1 Antagonis | 1990 |
Cetirizine. A review of its pharmacological properties and clinical potential in allergic rhinitis, pollen-induced asthma, and chronic urticaria.
Topics: Animals; Asthma; Cetirizine; Chronic Disease; Histamine H1 Antagonists; Humans; Hydroxyzine; Pollen; | 1990 |
Three new non-sedative antihistamines: worth keeping an eye open for.
Topics: Cetirizine; Cyproheptadine; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Rhinitis, All | 1990 |
35 trials available for hydroxyzine and Hives
| Article | Year |
|---|---|
Night-time sedating H1 -antihistamine increases daytime somnolence but not treatment efficacy in chronic spontaneous urticaria: a randomized controlled trial.
Topics: Adult; Aged; Cetirizine; Chronic Disease; Cross-Over Studies; Double-Blind Method; Drug Administrati | 2014 |
Treatment of chronic autoimmune urticaria with omalizumab.
Topics: Adult; Anti-Allergic Agents; Antibodies, Anti-Idiotypic; Antibodies, Monoclonal; Antibodies, Monoclo | 2008 |
Efficacy of leukotriene receptor antagonist with an anti-H1 receptor antagonist for treatment of chronic idiopathic urticaria.
Topics: Acetates; Adolescent; Adult; Cetirizine; Chronic Disease; Cyclopropanes; Drug Therapy, Combination; | 2009 |
Suppression of histamine- and allergen-induced skin reactions: comparison of first- and second-generation antihistamines.
Topics: Adult; Allergens; Animals; Dermatophagoides pteronyssinus; Dibenzazepines; Double-Blind Method; Fema | 2009 |
The effect of H1 and H2 blockade on cutaneous histamine response in man.
Topics: Cimetidine; Dose-Response Relationship, Immunologic; Histamine H1 Antagonists; Histamine H2 Antagoni | 1980 |
Combined H1 and H2 antihistamine therapy in chronic urticaria.
Topics: Adult; Aged; Chronic Disease; Cimetidine; Double-Blind Method; Drug Therapy, Combination; Evaluation | 1981 |
A controlled trial of therapy in chronic urticaria.
Topics: Adult; Chlorpheniramine; Chronic Disease; Cimetidine; Clinical Trials as Topic; Cyproheptadine; Drug | 1981 |
Comparison of cinnarizine, cyproheptadine, doxepin, and hydroxyzine in treatment of idiopathic cold urticaria: usefulness of doxepin.
Topics: Adolescent; Adult; Cinnarizine; Cold Temperature; Cyproheptadine; Doxepin; Female; Humans; Hydroxyzi | 1984 |
Atarax (hydroxyzine) for itching.
Topics: Clinical Trials as Topic; Humans; Hydroxyzine; Pruritus; Urticaria | 1980 |
Outpatient management of acute urticaria: the role of prednisone.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Analysis of Variance; Anti-Inflammatory Agen | 1995 |
Effect of the H2-antagonist cimetidine on the pharmacokinetics and pharmacodynamics of the H1-antagonists hydroxyzine and cetirizine in patients with chronic urticaria.
Topics: Adolescent; Adult; Aged; Cetirizine; Chronic Disease; Cimetidine; Double-Blind Method; Drug Combinat | 1995 |
Cetirizine versus hydroxyzine and placebo in chronic idiopathic urticaria.
Topics: Adult; Cetirizine; Chronic Disease; Double-Blind Method; Drug Tolerance; Female; Humans; Hydroxyzine | 1996 |
Treatment of pruritus in allergic dermatoses: an evaluation of the relative efficacy of cyproheptadine and hydroxyzine.
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Cyproheptadine; Dermatitis, Atopic; Dermatitis, C | 1976 |
Relative efficacy and safety of loratadine, hydroxyzine, and placebo in chronic idiopathic urticaria.
Topics: Adolescent; Adult; Aged; Chronic Disease; Double-Blind Method; Humans; Hydroxyzine; Loratadine; Midd | 1992 |
Therapeutic effects of cetirizine in delayed pressure urticaria: clinicopathologic findings.
Topics: Adult; Aged; Cetirizine; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Hydroxyzine; | 1991 |
Cetirizine vs placebo in chronic idiopathic urticaria--a double blind randomised cross-over study.
Topics: Adolescent; Adult; Cetirizine; Chronic Disease; Double-Blind Method; Female; Histamine H1 Antagonist | 1991 |
Controlled trial of H1 antagonists in the treatment of chronic idiopathic urticaria.
Topics: Adult; Aged; Astemizole; Chronic Disease; Diphenhydramine; Dose-Response Relationship, Drug; Double- | 1991 |
A comparison of cetirizine and terfenadine in the management of solar urticaria.
Topics: Adult; Aged; Cetirizine; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Hydroxyzine; | 1991 |
Effects of H1-antihistamine drug regimen on histamine release by nonlesional skin mast cells of patients with chronic urticaria.
Topics: Adult; Benzhydryl Compounds; Chronic Disease; Double-Blind Method; Female; Histamine H1 Antagonists; | 1990 |
A double-blind, single-dose, crossover comparison of cetirizine, terfenadine, loratadine, astemizole, and chlorpheniramine versus placebo: suppressive effects on histamine-induced wheals and flares during 24 hours in normal subjects.
Topics: Adult; Astemizole; Benzhydryl Compounds; Benzimidazoles; Cetirizine; Chlorpheniramine; Cyproheptadin | 1990 |
Comparison of cetirizine with astemizole in the treatment of perennial allergic rhinitis and study of the concomitant effect on histamine and allergen-induced wheal responses.
Topics: Adult; Astemizole; Benzimidazoles; Cetirizine; Double-Blind Method; Histamine H1 Antagonists; Humans | 1990 |
Comparison of cetirizine and terfenadine in the treatment of chronic idiopathic urticaria.
Topics: Benzhydryl Compounds; Cetirizine; Chronic Disease; Double-Blind Method; Histamine H1 Antagonists; Hu | 1990 |
Therapeutic effects of cetirizine in delayed pressure urticaria. Part 1. Effects on weight tests and skin-window cytology.
Topics: Adult; Aged; Cetirizine; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Hydroxyzine; | 1990 |
Cetirizine inhibits delayed pressure urticaria. Part 2. Skin biopsy findings.
Topics: Adult; Aged; Biopsy; Blood Cell Count; Cetirizine; Complement System Proteins; Female; Fibrin; Fluor | 1990 |
Urticaria: clinical efficacy of cetirizine in comparison with hydroxyzine and placebo.
Topics: Adolescent; Adult; Cetirizine; Child; Histamine H1 Antagonists; Humans; Hydroxyzine; Middle Aged; Ur | 1990 |
Acrivastine versus hydroxyzine in the treatment of cholinergic urticaria. A placebo-controlled study.
Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Exercise; Female; Hista | 1988 |
A comparison of acrivastine versus hydroxyzine and placebo in the treatment of chronic idiopathic urticaria.
Topics: Adult; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Female; Histamine H1 Antagoni | 1989 |
[Importance of Zyrtec in the treatment of chronic urticaria and allergic rhinopathies apropos of 1168 cases seen by hospital practitioners].
Topics: Adolescent; Adult; Cetirizine; Chronic Disease; Female; Histamine H1 Antagonists; Humans; Hydroxyzin | 1989 |
Double-blind, placebo-controlled study of terfenadine and hydroxyzine in patients with chronic idiopathic urticaria.
Topics: Adolescent; Adult; Benzhydryl Compounds; Chronic Disease; Double-Blind Method; Histamine H1 Antagoni | 1989 |
Treatment of chronic urticaria with cetirizine dihydrochloride a non-sedating antihistamine.
Topics: Adolescent; Adult; Aged; Cetirizine; Clinical Trials as Topic; Double-Blind Method; Female; Histamin | 1988 |
Comparison of the central and peripheral effects of cetirizine and terfenadine.
Topics: Adult; Benzhydryl Compounds; Cetirizine; Electroencephalography; Histamine; Histamine H1 Antagonists | 1988 |
Comparison of the efficacy of four antihistamines in chronic urticaria.
Topics: Adolescent; Adult; Chlorpheniramine; Chronic Disease; Cimetidine; Clemastine; Double-Blind Method; D | 1988 |
Inhibiting effect of cetirizine on histamine-induced and 48/80-induced wheals and flares, experimental dermographism, and cold-induced urticaria.
Topics: Adult; Cetirizine; Chemical Phenomena; Chemistry; Cold Temperature; Female; Histamine Antagonists; H | 1987 |
Attenuation of cutaneous reactivity to histamine by cetirizine and dexchlorpheniramine.
Topics: Adult; Cetirizine; Chlorpheniramine; Delayed-Action Preparations; Double-Blind Method; Fatigue; Fema | 1988 |
Some clinical aspects of cholinergic urticaria.
Topics: Adolescent; Adult; Baths; Brompheniramine; Child; Diagnosis, Differential; Female; Hot Temperature; | 1968 |
51 other studies available for hydroxyzine and Hives
| Article | Year |
|---|---|
Urticaria and edema in a 2-year-old boy.
Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Inflammatory Agents; Cetirizine; Child, Preschool; Diagnosi | 2021 |
Rash and a patch test result positive for cobalt in a patient with a hip replacement.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Hip; Cetirizine; Cobalt; Dapsone | 2014 |
Night-time sedating H1 antihistamine increases daytime somnolence but not treatment efficacy in chronic spontaneous urticaria: a randomized controlled study.
Topics: Female; Histamine H1 Antagonists; Humans; Hydroxyzine; Male; Sleep Wake Disorders; Urticaria | 2014 |
What the first 10,000 patients with chronic urticaria have taught me: a personal journey.
Topics: Allergens; Autoantibodies; Autoimmunity; Chronic Disease; Cyclosporine; Guidelines as Topic; Histami | 2009 |
[Pruritic urticarial papules and plaques of pregnancy].
Topics: Adult; Anti-Inflammatory Agents; Antipruritics; Betamethasone; Female; Humans; Hydrocortisone; Hydro | 2008 |
Dapsone hypersensitivity syndrome during delayed pressure urticaria treatment.
Topics: Adult; Dapsone; Dengue; Diagnosis, Differential; Drug Hypersensitivity; Erythema; Female; Fever; His | 2010 |
Chronic urticaria and angioedema.
Topics: Angioedema; Cetirizine; Chronic Disease; Histamine H1 Antagonists, Non-Sedating; Humans; Hydroxyzine | 2002 |
[Hydroxyzine hydrochloride in the treatment of urticaria factitia].
Topics: Humans; Hydroxyzine; Tranquilizing Agents; Urticaria | 1957 |
Hydroxyzine (atarax) in chronic urticaria and in allergic manifestations; clinical observations in man and experimental studies on asthma in guinea pigs produced by several agents.
Topics: Asthma; Chronic Disease; Guinea Pigs; Humans; Hydroxyzine; Male; Tranquilizing Agents; Urticaria | 1958 |
[Cases of pruritic skin diseases, particularly chronic urticaria, cured with Atarax].
Topics: Chronic Disease; Humans; Hydroxyzine; Pruritus; Skin; Urticaria | 1963 |
Effects of calcineurin inhibitors on an in vitro assay for chronic urticaria.
Topics: Basophils; Calcineurin Inhibitors; Cells, Cultured; Chronic Disease; Complement C5a; Cyclosporine; D | 2005 |
Severe cholinergic urticaria successfully treated with scopolamine butylbromide in addition to antihistamines.
Topics: Adult; Butylscopolammonium Bromide; Drug Therapy, Combination; Exercise; Famotidine; Histamine H1 An | 2006 |
A case of urticaria induced by both hydroxyzine and cetirizine but not by levocetirizine.
Topics: Adult; Cetirizine; Histamine H1 Antagonists; Humans; Hydroxyzine; Male; Piperazines; Urticaria | 2007 |
Depressive symptoms in urticaria patients treated with first- or second-generation histamine 1 receptor antagonists.
Topics: Adult; Aged; Cetirizine; Depressive Disorder; Female; Histamine H1 Antagonists; Histamine H1 Antagon | 2007 |
Solar urticaria: a case with increased skin mast cells and good therapeutic response to an antihistamine.
Topics: Adult; Female; Histamine H1 Antagonists; Humans; Hydroxyzine; Mast Cells; Skin; Sunlight; Urticaria | 1980 |
Histamine release and therapy of severe dermatographism.
Topics: Adolescent; Animals; Cyproheptadine; Diphenhydramine; Female; Histamine; Histamine Release; Humans; | 1981 |
Exercise-induced hives.
Topics: Cimetidine; Cold Temperature; Cyproheptadine; Histamine; Humans; Hydroxyzine; Hypotension; Methachol | 1984 |
Follicular dermographism.
Topics: Adolescent; Adult; Female; Humans; Hydroxyzine; Male; Middle Aged; Physical Stimulation; Pruritus; U | 1983 |
Life-threatening idiopathic anaphylaxis associated with hyperimmunoglobulinemia E.
Topics: Anaphylaxis; Cimetidine; Coronary Disease; Diphenhydramine; Humans; Hydroxyzine; Hypergammaglobuline | 1984 |
Urticaria.
Topics: Allergens; Cimetidine; Cyproheptadine; Humans; Hydroxyzine; Urticaria | 1982 |
Evaluation of a patient with both aquagenic and cholinergic urticaria.
Topics: Anxiety; Child; Cholinergic Fibers; Female; Heart Rate; Histamine; Hot Temperature; Humans; Hydroxyz | 1981 |
Skin reactions to hydroxyzine.
Topics: Adult; Aged; Dermatitis, Atopic; Drug Eruptions; Female; Histamine H1 Antagonists; Humans; Hydroxyzi | 1997 |
Hypersensitivity to H1-antihistamines.
Topics: Chlorpheniramine; Drug Hypersensitivity; Female; Histamine H1 Antagonists; Humans; Hydroxyzine; Hype | 2000 |
[A case of acute urticaria from hydroxyzine hydrochloride used for preanesthetic medication].
Topics: Acute Disease; Aged; Anti-Anxiety Agents; Humans; Hydroxyzine; Male; Preanesthetic Medication; Skin | 2000 |
Urticaria.
Topics: Anti-Anxiety Agents; Attitude of Health Personnel; Dermatologic Agents; Dermatology; Food Hypersensi | 1978 |
Relieving localized and generalized pruritus.
Topics: Aged; Bandages; Chlorpromazine; Cyproheptadine; Dermatitis; Dermatitis, Seborrheic; Female; Humans; | 1975 |
Urticaria: Diagnosis and management.
Topics: Adrenal Cortex Hormones; Angioedema; Anti-Anxiety Agents; Aspirin; Drug Hypersensitivity; Ephedrine; | 1975 |
Urticaria and giardia lamblia infection.
Topics: Adult; Female; Giardiasis; Humans; Hydroxyzine; Urticaria | 1979 |
Urticaria of unknown origin.
Topics: Epinephrine; Humans; Hydroxyzine; Male; Middle Aged; Prednisone; Urticaria | 1979 |
Treatment of cold urticaria.
Topics: Adult; Cimetidine; Cold Temperature; Cyproheptadine; Diphenhydramine; Drug Therapy, Combination; Hum | 1979 |
Urticaria and angio-oedema.
Topics: Acute Disease; Angioedema; Chronic Disease; Cyproheptadine; Humans; Hydroxyzine; Urticaria | 1978 |
[Use of hydroxyzine hydrochlorate in the treatment of chronic urticaria].
Topics: Adolescent; Child; Child, Preschool; Chronic Disease; Drug Evaluation; Female; Humans; Hydroxyzine; | 1975 |
[Use of hydroxyzine chloride in the treatment of chronic urticaria].
Topics: Administration, Oral; Adolescent; Body Weight; Child; Child, Preschool; Chronic Disease; Female; Hum | 1975 |
Treatment with high dose mouse monoclonal (anti-GD3) antibody R24 in patients with metastatic melanoma.
Topics: Adult; Animals; Antibodies, Anti-Idiotypic; Antibodies, Monoclonal; Antigens, CD; Cimetidine; Comple | 1992 |
Aquagenic urticaria.
Topics: Child; Combined Modality Therapy; Cyproheptadine; Humans; Hydroxyzine; Male; Parasympathetic Nervous | 1992 |
Treatment of urticaria and angioedema: low-sedating H1-type antihistamines.
Topics: Angioedema; Astemizole; Benzhydryl Compounds; Benzimidazoles; Cetirizine; Cyproheptadine; Histamine | 1991 |
Oral cyclosporine for severe chronic idiopathic urticaria and angioedema.
Topics: Administration, Oral; Adult; Angioedema; Chronic Disease; Cyclosporine; Female; Follow-Up Studies; H | 1991 |
Effect of cetirizine on cutaneous reactions to PAF, kallikrein and serum in patients with chronic urticaria.
Topics: Adult; Blood Transfusion, Autologous; Cetirizine; Chronic Disease; Female; Histamine; Histamine H1 A | 1990 |
[Cetirizine in allergic symptoms. General practice relevance and a profile of effects. Resume of current studies].
Topics: Asthma; Cetirizine; Eosinophils; Histamine H1 Antagonists; Humans; Hydroxyzine; Rhinitis, Allergic, | 1990 |
Late-phase cutaneous reactions to platelet activating factor and kallikrein in urticaria.
Topics: Adult; Cetirizine; Chronic Disease; Female; Histamine H1 Antagonists; Humans; Hydroxyzine; Hypersens | 1990 |
Cimetidine increases the plasma concentration of hydroxyzine.
Topics: Chronic Disease; Cimetidine; Drug Interactions; Drug Therapy, Combination; Humans; Hydroxyzine; Urti | 1986 |
The natural history and response to therapy of chronic urticaria and angioedema.
Topics: Adrenal Cortex Hormones; Adult; Angioedema; Chronic Disease; Cimetidine; Female; Histamine H1 Antago | 1989 |
Exercise-induced allergic syndromes on the increase.
Topics: Adolescent; Adult; Albuterol; Anaphylaxis; Asthma; Asthma, Exercise-Induced; Beclomethasone; Exercis | 1989 |
Vibratory urticaria associated with bladder-wall infection with the yeast Torulopsis glabrata.
Topics: Candidiasis; Female; Humans; Hydroxyzine; Ketoconazole; Middle Aged; Occupational Diseases; Urinary | 1989 |
Urticarial vasculitis in adults.
Topics: Adult; Aged; Biopsy; Female; Humans; Hydroxyzine; Immune Complex Diseases; Male; Sunlight; Urticaria | 1988 |
[Dermatographic urticaria: evaluation of the therapeutic efficacy of drugs using a dermatographic tester].
Topics: Adolescent; Adult; Benzhydryl Compounds; Chronic Disease; Cinnarizine; Female; Humans; Hydroxyzine; | 1987 |
Ethanol-induced urticaria: a case report.
Topics: Adult; Cytoplasmic Granules; Double-Blind Method; Ethanol; Histamine; Humans; Hydroxyzine; Male; Mas | 1988 |
The unremarkable brown recluse spider bite.
Topics: Adult; California; Erythema; Female; Humans; Hydroxyzine; Lymphocyte Activation; Missouri; Pruritus; | 1973 |
Photo-urticaria.
Topics: Adult; Female; Humans; Hydroxyzine; Photosensitivity Disorders; Sunlight; Urticaria | 1971 |
An investigative and clinical evaluation of dermographism.
Topics: Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Dermatitis, Atopic; Edema; Erythema; | 1970 |
Urticarial dermographism. Report of occurrence in identical twins: a method for quantitating urticarial skin sensitivity.
Topics: Adolescent; Diseases in Twins; Humans; Hydroxyzine; Male; Urticaria | 1966 |