hydroxyzine has been researched along with Hepatitis C in 2 studies
Hydroxyzine: A histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.
hydroxyzine : A N-alkylpiperazine that is piperzine in which the nitrogens atoms are substituted by 2-(2-hydroxyethoxy)ethyl and (4-chlorophenyl)(phenyl)methyl groups respectively.
Hepatitis C: INFLAMMATION of the LIVER in humans caused by HEPATITIS C VIRUS, a single-stranded RNA virus. Its incubation period is 30-90 days. Hepatitis C is transmitted primarily by contaminated blood parenterally and is often associated with transfusion and intravenous drug abuse. However, in a significant number of cases, the source of hepatitis C infection is unknown.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Recently, we reported that chlorcyclizine (CCZ, Rac-2), an over-the-counter antihistamine piperazine drug, possesses in vitro and in vivo activity against hepatitis C virus." | 7.83 | Discovery, Optimization, and Characterization of Novel Chlorcyclizine Derivatives for the Treatment of Hepatitis C Virus Infection. ( Dulcey, AE; Ferrer, M; He, S; Hu, X; Hu, Z; Liang, TJ; Lin, B; Marugan, JJ; Rolt, A; Southall, N; Wang, AQ; Xiao, J; Xu, X; Zheng, W, 2016) |
| "Recently, we reported that chlorcyclizine (CCZ, Rac-2), an over-the-counter antihistamine piperazine drug, possesses in vitro and in vivo activity against hepatitis C virus." | 3.83 | Discovery, Optimization, and Characterization of Novel Chlorcyclizine Derivatives for the Treatment of Hepatitis C Virus Infection. ( Dulcey, AE; Ferrer, M; He, S; Hu, X; Hu, Z; Liang, TJ; Lin, B; Marugan, JJ; Rolt, A; Southall, N; Wang, AQ; Xiao, J; Xu, X; Zheng, W, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| He, S | 1 |
| Xiao, J | 1 |
| Dulcey, AE | 1 |
| Lin, B | 1 |
| Rolt, A | 1 |
| Hu, Z | 1 |
| Hu, X | 1 |
| Wang, AQ | 1 |
| Xu, X | 1 |
| Southall, N | 1 |
| Ferrer, M | 1 |
| Zheng, W | 1 |
| Liang, TJ | 1 |
| Marugan, JJ | 1 |
| Mingorance, L | 1 |
| Friesland, M | 1 |
| Coto-Llerena, M | 1 |
| Pérez-del-Pulgar, S | 1 |
| Boix, L | 1 |
| López-Oliva, JM | 1 |
| Bruix, J | 1 |
| Forns, X | 1 |
| Gastaminza, P | 1 |
2 other studies available for hydroxyzine and Hepatitis C
| Article | Year |
|---|---|
Discovery, Optimization, and Characterization of Novel Chlorcyclizine Derivatives for the Treatment of Hepatitis C Virus Infection.
Topics: Dose-Response Relationship, Drug; Drug Discovery; Hepacivirus; Hepatitis C; Microbial Sensitivity Te | 2016 |
Selective inhibition of hepatitis C virus infection by hydroxyzine and benztropine.
Topics: Antiviral Agents; Benztropine; Biological Assay; Cell Culture Techniques; Drug Therapy, Combination; | 2014 |