hydroxyzine has been researched along with Hepatic Encephalopathy in 1 studies
Hydroxyzine: A histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.
hydroxyzine : A N-alkylpiperazine that is piperzine in which the nitrogens atoms are substituted by 2-(2-hydroxyethoxy)ethyl and (4-chlorophenyl)(phenyl)methyl groups respectively.
Hepatic Encephalopathy: A syndrome characterized by central nervous system dysfunction in association with LIVER FAILURE, including portal-systemic shunts. Clinical features include lethargy and CONFUSION (frequently progressing to COMA); ASTERIXIS; NYSTAGMUS, PATHOLOGIC; brisk oculovestibular reflexes; decorticate and decerebrate posturing; MUSCLE SPASTICITY; and bilateral extensor plantar reflexes (see REFLEX, BABINSKI). ELECTROENCEPHALOGRAPHY may demonstrate triphasic waves. (From Adams et al., Principles of Neurology, 6th ed, pp1117-20; Plum & Posner, Diagnosis of Stupor and Coma, 3rd ed, p222-5)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sleep difficulty is common in minimal hepatic encephalopathy (HE) and the mechanisms are not fully elucidated." | 6.73 | Histamine H1 blocker hydroxyzine improves sleep in patients with cirrhosis and minimal hepatic encephalopathy: a randomized controlled pilot trial. ( Annoni, JM; Coeytaux, A; Giostra, E; Hadengue, A; Spahr, L, 2007) |
| "Sleep difficulty is common in minimal hepatic encephalopathy (HE) and the mechanisms are not fully elucidated." | 2.73 | Histamine H1 blocker hydroxyzine improves sleep in patients with cirrhosis and minimal hepatic encephalopathy: a randomized controlled pilot trial. ( Annoni, JM; Coeytaux, A; Giostra, E; Hadengue, A; Spahr, L, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Spahr, L | 1 |
| Coeytaux, A | 1 |
| Giostra, E | 1 |
| Hadengue, A | 1 |
| Annoni, JM | 1 |
1 trial available for hydroxyzine and Hepatic Encephalopathy
| Article | Year |
|---|---|
Histamine H1 blocker hydroxyzine improves sleep in patients with cirrhosis and minimal hepatic encephalopathy: a randomized controlled pilot trial.
Topics: Adult; Aged; Double-Blind Method; Female; Hepatic Encephalopathy; Histamine H1 Antagonists; Humans; | 2007 |