hydroxyzine has been researched along with Head and Neck Neoplasms in 4 studies
Hydroxyzine: A histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.
hydroxyzine : A N-alkylpiperazine that is piperzine in which the nitrogens atoms are substituted by 2-(2-hydroxyethoxy)ethyl and (4-chlorophenyl)(phenyl)methyl groups respectively.
Head and Neck Neoplasms: Soft tissue tumors or cancer arising from the mucosal surfaces of the LIP; oral cavity; PHARYNX; LARYNX; and cervical esophagus. Other sites included are the NOSE and PARANASAL SINUSES; SALIVARY GLANDS; THYROID GLAND and PARATHYROID GLANDS; and MELANOMA and non-melanoma skin cancers of the head and neck. (from Holland et al., Cancer Medicine, 4th ed, p1651)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The efficacy and safety of granisetron alone (group G) and granisetron plus hydroxyzine hydrochloride (group G/H) as prophylactic therapy for acute and delayed nausea and vomiting were evaluated in an open trial in head and neck cancer patients undergoing chemotherapy with cisplatin." | 9.08 | Comparison of granisetron alone and granisetron plus hydroxyzine hydrochloride for prophylactic treatment of emesis induced by cisplatin chemotherapy. ( Enomoto, H; Furukawa, M; Furukawa, S; Kokatsu, T; Kubota, A; Tsukuda, M, 1995) |
| "The comparative study among granisetron alone and granisetron combined with hydroxyzine hydrochloride or dexamethasone was undertaken for the prevention of nausea and vomiting during chemotherapy including cisplatin in patients with advanced head and neck carcinomas." | 9.08 | [Comparison of granisetron alone and granisetron plus dexamethasone or hydroxyzine hydrochloride for the prevention of nausea and vomiting during chemotherapy including cisplatin]. ( Enomoto, H; Furukawa, M; Ikema, Y; Kawai, S; Kohno, H; Kubota, A; Makino, Y; Matsuda, H; Tsukuda, M; Yago, T, 1995) |
| "In this study, the utility and safety of granisetron alone (Group G) and granisetron plus hydroxyzine hydrochloride (Group G/H) for nausea and vomiting were evaluated in patients with head and neck cancer treated by cisplatin-containing chemotherapy." | 9.07 | [Comparison of granisetron alone and granisetron plus hydroxyzine hydrochloride for the prophylactic treatment of emesis induced by cisplatin-containing chemotherapy]. ( Enomoto, H; Furukawa, M; Furukawa, S; Kohno, H; Kokatsu, T; Kubota, A; Tsukuda, M, 1993) |
| "The efficacy and safety of granisetron alone (group G) and granisetron plus hydroxyzine hydrochloride (group G/H) as prophylactic therapy for acute and delayed nausea and vomiting were evaluated in an open trial in head and neck cancer patients undergoing chemotherapy with cisplatin." | 5.08 | Comparison of granisetron alone and granisetron plus hydroxyzine hydrochloride for prophylactic treatment of emesis induced by cisplatin chemotherapy. ( Enomoto, H; Furukawa, M; Furukawa, S; Kokatsu, T; Kubota, A; Tsukuda, M, 1995) |
| "The comparative study among granisetron alone and granisetron combined with hydroxyzine hydrochloride or dexamethasone was undertaken for the prevention of nausea and vomiting during chemotherapy including cisplatin in patients with advanced head and neck carcinomas." | 5.08 | [Comparison of granisetron alone and granisetron plus dexamethasone or hydroxyzine hydrochloride for the prevention of nausea and vomiting during chemotherapy including cisplatin]. ( Enomoto, H; Furukawa, M; Ikema, Y; Kawai, S; Kohno, H; Kubota, A; Makino, Y; Matsuda, H; Tsukuda, M; Yago, T, 1995) |
| "In this study, the utility and safety of granisetron alone (Group G) and granisetron plus hydroxyzine hydrochloride (Group G/H) for nausea and vomiting were evaluated in patients with head and neck cancer treated by cisplatin-containing chemotherapy." | 5.07 | [Comparison of granisetron alone and granisetron plus hydroxyzine hydrochloride for the prophylactic treatment of emesis induced by cisplatin-containing chemotherapy]. ( Enomoto, H; Furukawa, M; Furukawa, S; Kohno, H; Kokatsu, T; Kubota, A; Tsukuda, M, 1993) |
| "Twenty patients with end-stage head and neck cancer, unresponsive to either acetaminophen with codeine or oxycodone hydrochloride, were placed on a four-drug analgesic regimen consisting of methadone hydrochloride, Trilisate or acetaminophen, a tricyclic antidepressant, and, in most cases, hydroxyzine." | 1.29 | A four-drug pain regimen for head and neck cancers. ( Carrol, EN; Fine, E; Ruff, RL; Stepnick, D, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tsukuda, M | 3 |
| Furukawa, S | 2 |
| Kokatsu, T | 2 |
| Enomoto, H | 3 |
| Kubota, A | 3 |
| Furukawa, M | 3 |
| Carrol, EN | 1 |
| Fine, E | 1 |
| Ruff, RL | 1 |
| Stepnick, D | 1 |
| Kohno, H | 2 |
| Kawai, S | 1 |
| Yago, T | 1 |
| Matsuda, H | 1 |
| Ikema, Y | 1 |
| Makino, Y | 1 |
3 trials available for hydroxyzine and Head and Neck Neoplasms
| Article | Year |
|---|---|
Comparison of granisetron alone and granisetron plus hydroxyzine hydrochloride for prophylactic treatment of emesis induced by cisplatin chemotherapy.
Topics: Acute Disease; Adult; Aged; Antiemetics; Antineoplastic Agents; Cisplatin; Drug Therapy, Combination | 1995 |
[Comparison of granisetron alone and granisetron plus dexamethasone or hydroxyzine hydrochloride for the prevention of nausea and vomiting during chemotherapy including cisplatin].
Topics: Adult; Aged; Carcinoma, Squamous Cell; Cisplatin; Dexamethasone; Drug Therapy, Combination; Female; | 1995 |
[Comparison of granisetron alone and granisetron plus hydroxyzine hydrochloride for the prophylactic treatment of emesis induced by cisplatin-containing chemotherapy].
Topics: Adult; Aged; Cisplatin; Drug Therapy, Combination; Female; Granisetron; Head and Neck Neoplasms; Hum | 1993 |
1 other study available for hydroxyzine and Head and Neck Neoplasms
| Article | Year |
|---|---|
A four-drug pain regimen for head and neck cancers.
Topics: Acetaminophen; Adult; Aged; Antidepressive Agents, Tricyclic; Drug Administration Schedule; Drug The | 1994 |