hydroxyzine has been researched along with Dermatitis, Atopic in 21 studies
Hydroxyzine: A histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.
hydroxyzine : A N-alkylpiperazine that is piperzine in which the nitrogens atoms are substituted by 2-(2-hydroxyethoxy)ethyl and (4-chlorophenyl)(phenyl)methyl groups respectively.
Dermatitis, Atopic: A chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee. In infants it is known as infantile eczema.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The mean elimination half-life was 7." | 2.65 | Pharmacokinetics and antipruritic effects of hydroxyzine in children with atopic dermatitis. ( Becker, AB; Haydey, RP; Simons, FE; Simons, KJ, 1984) |
| "Hydroxyzine HCL (HHCL) is an antihistamine, used for the treatment of allergic skin conditions." | 1.62 | Formulation and assessment of hydroxyzine HCL solid lipid nanoparticles by dual emulsification technique for transdermal delivery. ( Ahmed, KA; El-Feky, YA; El-Telbany, DFA; El-Telbany, RFA; Zakaria, S, 2021) |
| " Therefore, the aim of the present study was to produce an effective drug-loaded dosage form that is able to control the release of hydroxyzine hydrochloride into the skin." | 1.37 | In vitro and in vivo evaluation of hydroxyzine hydrochloride microsponges for topical delivery. ( latif Aziz, R; Soliman, II; Zaki Rizkalla, CM, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (38.10) | 18.7374 |
| 1990's | 6 (28.57) | 18.2507 |
| 2000's | 3 (14.29) | 29.6817 |
| 2010's | 3 (14.29) | 24.3611 |
| 2020's | 1 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| El-Telbany, DFA | 1 |
| El-Telbany, RFA | 1 |
| Zakaria, S | 1 |
| Ahmed, KA | 1 |
| El-Feky, YA | 1 |
| Eichenseer, M | 1 |
| Johansen, C | 1 |
| Mueller, RS | 1 |
| Bäumer, W | 1 |
| Stahl, J | 1 |
| Sander, K | 1 |
| Petersen, LJ | 1 |
| Paps, J | 1 |
| Stark, H | 1 |
| Kietzmann, M | 1 |
| Olivry, T | 1 |
| Zaki Rizkalla, CM | 1 |
| latif Aziz, R | 1 |
| Soliman, II | 1 |
| Peroni, DG | 1 |
| Dall'Agnola, A | 1 |
| Piacentini, GL | 1 |
| Boner, AL | 1 |
| Deutsch, PH | 1 |
| Simons, FE | 1 |
| Simons, KJ | 1 |
| Becker, AB | 1 |
| Haydey, RP | 1 |
| Lipman, BL | 1 |
| Rihoux, JP | 1 |
| Polderman, J | 1 |
| Klein, GL | 1 |
| Galant, SP | 1 |
| Paterson, S | 1 |
| Ganir, EM | 1 |
| Capulong, MC | 1 |
| Tahara, K | 1 |
| Akasawa, A | 1 |
| Iikura, Y | 1 |
| Michel, M | 1 |
| Dompmartin, A | 1 |
| Louvet, S | 1 |
| Szczurko, C | 1 |
| Castel, B | 1 |
| Leroy, D | 1 |
| Wergowske, GL | 1 |
| Zur, G | 1 |
| Ihrke, PJ | 1 |
| White, SD | 1 |
| Kass, PH | 1 |
| Baraf, CS | 1 |
| De Vos, C | 2 |
| Michel, L | 1 |
| Dubertret, L | 1 |
| Massey, WA | 1 |
| Lichtenstein, LM | 1 |
| Soschin, D | 1 |
| Leyden, JJ | 1 |
| Grolnick, M | 1 |
2 reviews available for hydroxyzine and Dermatitis, Atopic
| Article | Year |
|---|---|
Pharmacologic modulation of allergic cutaneous inflammation.
Topics: Allergens; Cetirizine; Dermatitis, Atopic; Eosinophils; Histamine H1 Antagonists; Humans; Hydroxyzin | 1990 |
The effects of antihistamines beyond H1 antagonism in allergic inflammation.
Topics: Benzhydryl Compounds; Cetirizine; Cyproheptadine; Dermatitis, Atopic; Histamine H1 Antagonists; Hist | 1990 |
7 trials available for hydroxyzine and Dermatitis, Atopic
| Article | Year |
|---|---|
Efficacy of dimetinden and hydroxyzine/chlorpheniramine in atopic dogs: a randomised, controlled, double-blinded trial.
Topics: Animals; Antipruritics; Chlorpheniramine; Cross-Over Studies; Dermatitis, Atopic; Dimethindene; Dog | 2013 |
Pharmacokinetics and antipruritic effects of hydroxyzine in children with atopic dermatitis.
Topics: Antipruritics; Child; Child, Preschool; Clinical Trials as Topic; Dermatitis, Atopic; Dermatologic A | 1984 |
A comparison of the antipruritic efficacy of hydroxyzine and cyproheptadine in children with atopic dermatitis.
Topics: Adolescent; Antipruritics; Child; Child, Preschool; Cyproheptadine; Dermatitis, Atopic; Dermatologic | 1980 |
Additive benefits of EFAs in dogs with atopic dermatitis after partial response to antihistamine therapy.
Topics: Animals; Chlorpheniramine; Clemastine; Cyproheptadine; Dermatitis, Atopic; Dog Diseases; Dogs; Drug | 1995 |
Treatment of pruritus in allergic dermatoses: an evaluation of the relative efficacy of cyproheptadine and hydroxyzine.
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Cyproheptadine; Dermatitis, Atopic; Dermatitis, C | 1976 |
Cetirizine effects on the cutaneous allergic reaction in humans.
Topics: Adult; Allergens; Cetirizine; Dermatitis, Atopic; Double-Blind Method; Female; Histamine; Histamine | 1990 |
The effects of antihistamines beyond H1 antagonism in allergic inflammation.
Topics: Benzhydryl Compounds; Cetirizine; Cyproheptadine; Dermatitis, Atopic; Histamine H1 Antagonists; Hist | 1990 |
13 other studies available for hydroxyzine and Dermatitis, Atopic
| Article | Year |
|---|---|
Formulation and assessment of hydroxyzine HCL solid lipid nanoparticles by dual emulsification technique for transdermal delivery.
Topics: Administration, Cutaneous; Animals; Antipruritics; Dermatitis, Atopic; Disease Models, Animal; Drug | 2021 |
Lack of preventing effect of systemically and topically administered histamine H(1) or H(4) receptor antagonists in a dog model of acute atopic dermatitis.
Topics: Aging; Animals; Antigens, Dermatophagoides; Cetirizine; Dermatitis, Atopic; Dermatophagoides farinae | 2011 |
In vitro and in vivo evaluation of hydroxyzine hydrochloride microsponges for topical delivery.
Topics: Acrylic Resins; Administration, Cutaneous; Animals; Antipruritics; Delayed-Action Preparations; Derm | 2011 |
Worsening of atopic dermatitis by hazelnut essence contained in hydroxyzine syrup.
Topics: Administration, Oral; Child, Preschool; Corylus; Dermatitis, Atopic; Drug Carriers; Egg Hypersensiti | 2007 |
Dermatographism treated with hydroxyzine and cimetidine and ranitidine.
Topics: Adult; Cimetidine; Dermatitis, Atopic; Drug Therapy, Combination; Humans; Hydroxyzine; Male; Pruritu | 1984 |
Atopic dermatitis in an infant complicated by generalized verrucae vulgares.
Topics: Coal Tar; Dermatitis, Atopic; Humans; Hydrocortisone; Hydroxyzine; Infant; Infant, Newborn; Male; Oi | 1983 |
The effect of clemastine and hydroxyzine on cutaneous histamine response in man.
Topics: Adult; Clemastine; Dermatitis, Atopic; Female; Histamine; Humans; Hydroxyzine; Male; Middle Aged; Py | 1982 |
Treatment of atopic dermatitis in children: the importance of skin care and environmental control.
Topics: Administration, Topical; Anti-Allergic Agents; Anti-Inflammatory Agents; Baths; Bedding and Linens; | 1996 |
Skin reactions to hydroxyzine.
Topics: Adult; Aged; Dermatitis, Atopic; Drug Eruptions; Female; Histamine H1 Antagonists; Humans; Hydroxyzi | 1997 |
Treatment-resistant atopic dermatitis.
Topics: Acetates; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Antipruritics; Cyclopropanes; Dermatiti | 2001 |
Antihistamines in the management of canine atopic dermatitis: a retrospective study of 171 dogs (1992-1998).
Topics: Allergens; Animals; Chlorpheniramine; Clemastine; Dermatitis, Atopic; Diphenhydramine; Dog Diseases; | 2002 |
Sorbic acid-induced erythema and edema.
Topics: Administration, Topical; Anti-Inflammatory Agents; Aspirin; Betamethasone Valerate; Capsaicin; Cosme | 1986 |
An investigative and clinical evaluation of dermographism.
Topics: Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Dermatitis, Atopic; Edema; Erythema; | 1970 |