hydroxyzine has been researched along with Delayed Hypersensitivity in 10 studies
Hydroxyzine: A histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.
hydroxyzine : A N-alkylpiperazine that is piperzine in which the nitrogens atoms are substituted by 2-(2-hydroxyethoxy)ethyl and (4-chlorophenyl)(phenyl)methyl groups respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Because the older antihistamines possessed relatively weak antihistaminic action, as well as sedative and anticholinergic effects, they could not be administered in doses high enough to confer relief to atopic patients with asthma." | 8.78 | Antihistamines in the treatment of clinical asthma. ( Rafferty, P, 1990) |
| "The effects of oral administration of the antihistamine cetirizine on the weal and flare caused by intradermal injection of platelet activating factor (PAF-acether), kallikrein, histamine and the patient's own serum were investigated in 10 patients with chronic urticaria." | 7.68 | Effect of cetirizine on cutaneous reactions to PAF, kallikrein and serum in patients with chronic urticaria. ( Juhlin, L; Rihoux, JP, 1990) |
| "Because the older antihistamines possessed relatively weak antihistaminic action, as well as sedative and anticholinergic effects, they could not be administered in doses high enough to confer relief to atopic patients with asthma." | 4.78 | Antihistamines in the treatment of clinical asthma. ( Rafferty, P, 1990) |
| "The effects of oral administration of the antihistamine cetirizine on the weal and flare caused by intradermal injection of platelet activating factor (PAF-acether), kallikrein, histamine and the patient's own serum were investigated in 10 patients with chronic urticaria." | 3.68 | Effect of cetirizine on cutaneous reactions to PAF, kallikrein and serum in patients with chronic urticaria. ( Juhlin, L; Rihoux, JP, 1990) |
| " The mean elimination half-life calculated from the terminal linear portion of the serum hydroxyzine concentration vs." | 1.27 | The pharmacokinetics and antihistaminic of the H1 receptor antagonist hydroxyzine. ( Frith, EM; Simons, FE; Simons, KJ, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (30.00) | 18.7374 |
| 1990's | 7 (70.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Simons, FE | 1 |
| Simons, KJ | 1 |
| Frith, EM | 1 |
| Townley, RG | 1 |
| Okada, C | 1 |
| Varney, V | 1 |
| Gaga, M | 1 |
| Frew, AJ | 1 |
| De Vos, C | 1 |
| Kay, AB | 1 |
| Juhlin, L | 2 |
| Rihoux, JP | 2 |
| Henocq, E | 1 |
| Rafferty, P | 1 |
| Reunala, T | 1 |
| Brummer-Korvenkontio, H | 1 |
| Lappalainen, P | 1 |
| Räsänen, L | 1 |
| Palosuo, T | 1 |
| Charlesworth, EN | 1 |
| Kagey-Sobotka, A | 1 |
| Norman, PS | 1 |
| Lichtenstein, LM | 1 |
| Ting, S | 1 |
| Rauls, DO | 1 |
| Reiman, BE | 1 |
3 reviews available for hydroxyzine and Delayed Hypersensitivity
| Article | Year |
|---|---|
Use of cetirizine to investigate non-H1 effects of second-generation antihistamines.
Topics: Cetirizine; Histamine Antagonists; Histamine H1 Antagonists; Humans; Hydroxyzine; Hypersensitivity; | 1992 |
Antihistamines in the treatment of clinical asthma.
Topics: Animals; Asthma; Benzhydryl Compounds; Cetirizine; Dose-Response Relationship, Drug; Forced Expirato | 1990 |
Immunology and treatment of mosquito bites.
Topics: Animals; Cetirizine; Culicidae; Histamine H1 Antagonists; Humans; Hydroxyzine; Hypersensitivity, Del | 1990 |
3 trials available for hydroxyzine and Delayed Hypersensitivity
| Article | Year |
|---|---|
The effect of a single oral dose of prednisolone or cetirizine on inflammatory cells infiltrating allergen-induced cutaneous late-phase reactions in atopic subjects.
Topics: Administration, Oral; Adolescent; Adult; Allergens; Cetirizine; Double-Blind Method; Histamine H1 An | 1992 |
Effect of cetirizine on mast cell-mediator release and cellular traffic during the cutaneous late-phase reaction.
Topics: Adolescent; Adult; Cell Count; Cell Movement; Cetirizine; Double-Blind Method; Female; Granulocytes; | 1989 |
Inhibitory effect of hydroxyzine on antigen-induced histamine release in vivo.
Topics: Administration, Oral; Adult; Antigens; Biopsy; Histamine Release; Hot Temperature; Humans; Hydroxyzi | 1985 |
4 other studies available for hydroxyzine and Delayed Hypersensitivity
| Article | Year |
|---|---|
The pharmacokinetics and antihistaminic of the H1 receptor antagonist hydroxyzine.
Topics: Adult; Chromatography, High Pressure Liquid; Female; Histamine H1 Antagonists; Humans; Hydroxyzine; | 1984 |
Effect of cetirizine on cutaneous reactions to PAF, kallikrein and serum in patients with chronic urticaria.
Topics: Adult; Blood Transfusion, Autologous; Cetirizine; Chronic Disease; Female; Histamine; Histamine H1 A | 1990 |
Does reversed-type anaphylaxis in healthy subjects mimic a real allergic reaction?
Topics: Adolescent; Adult; Anaphylaxis; Antigen-Antibody Reactions; Cell Movement; Cetirizine; Double-Blind | 1990 |
Late-phase cutaneous reactions to platelet activating factor and kallikrein in urticaria.
Topics: Adult; Cetirizine; Chronic Disease; Female; Histamine H1 Antagonists; Humans; Hydroxyzine; Hypersens | 1990 |