Page last updated: 2024-10-28

hydroxyzine and Bladder Pain Syndrome

hydroxyzine has been researched along with Bladder Pain Syndrome in 13 studies

Hydroxyzine: A histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.
hydroxyzine : A N-alkylpiperazine that is piperzine in which the nitrogens atoms are substituted by 2-(2-hydroxyethoxy)ethyl and (4-chlorophenyl)(phenyl)methyl groups respectively.

Research Excerpts

ExcerptRelevanceReference
"Hydroxyzine is a useful drug for the symptomatic treatment of IC, especially in patients with documented allergies and/or evidence of bladder mast cell activation."2.68Hydroxyzine therapy for interstitial cystitis. ( Sant, GR; Theoharides, TC, 1997)
"Interstitial cystitis (IC) and bladder pain syndrome (BPS) are chronic conditions that can be debilitating for patients."2.58An evaluation of the pharmacotherapy for interstitial cystitis. ( Giusto, LL; Shoskes, DA; Zahner, PM, 2018)
"The so-called interstitial cystitis is a chronic pain syndrome rather than a purely end organ disease of the urinary bladder."2.44[The complexity of chronic pelvic pain exemplified by the condition currently called interstitial cystitis. Part 2: Treatment]. ( Binder, I; Rossbach, G; van Ophoven, A, 2008)
"Symptoms of interstitial cystitis can usually be successfully managed with heparinoid therapy to theoretically alter bladder urothelial abnormalities, and with oral medications to inhibit neural upregulation or to control mast cell dysfunction."2.44Rational approaches to the treatment of patients with interstitial cystitis. ( Evans, RJ; Moldwin, RM; Rosenberg, MT; Stanford, EJ, 2007)
"Interstitial cystitis/painful bladder syndrome is a chronic disease characterized by pain, frequency, urgency, and nocturia and diagnosed primarily in women."2.44Interstitial cystitis/painful bladder syndrome. ( Warren, JW, 2007)
"Interstitial cystitis is more common than previously thought and is often diagnosed only when pain, frequency, and urgency become continuous and severe."2.43Interstitial cystitis: a primary care perspective. ( Page, S; Parsons, CL; Rosenberg, M, 2005)
"Amitriptyline was prescribed to 223 women with IC/BPS, only 125 of which (56%) had a documented history of depression."1.72Do medication prescription patterns follow guidelines in a cohort of women with interstitial cystitis/bladder pain syndrome? ( Anger, JT; Barbour, KE; Bresee, C; De Hoedt, AM; Freedland, SJ; Kim, J; Tholemeier, LN, 2022)
"Interstitial cystitis is associated with substantial costs and health care resource utilization."1.35Treatment modalities, health care resource utilization, and costs in patients diagnosed with interstitial cystitis. ( Chen, A; Lunacsek, OE; Sand, PK; Stanford, EJ; Wan, GJ, 2008)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.69)18.2507
2000's9 (69.23)29.6817
2010's2 (15.38)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Tholemeier, LN1
Bresee, C1
De Hoedt, AM1
Barbour, KE1
Kim, J1
Freedland, SJ1
Anger, JT1
Giusto, LL1
Zahner, PM1
Shoskes, DA1
Dancel, R1
Mounsey, A1
Handler, L1
Stanford, EJ2
Chen, A1
Wan, GJ1
Lunacsek, OE1
Sand, PK1
Binder, I1
Rossbach, G1
van Ophoven, A1
Myers, DL1
Sea, J1
Teichman, JM1
Rosenberg, M1
Parsons, CL1
Page, S1
Moldwin, RM1
Evans, RJ1
Rosenberg, MT2
Warren, JW1
Hazzard, MA1
Page, SA1
Theoharides, TC1
Sant, GR1
Sievert, KD1
Edenfeld, KD1
Oberpenning, F1
Piechota, HJ1

Reviews

7 reviews available for hydroxyzine and Bladder Pain Syndrome

ArticleYear
An evaluation of the pharmacotherapy for interstitial cystitis.
    Expert opinion on pharmacotherapy, 2018, Volume: 19, Issue:10

    Topics: Amitriptyline; Antibodies, Monoclonal; Antidepressive Agents, Tricyclic; Cimetidine; Cystitis, Inter

2018
[The complexity of chronic pelvic pain exemplified by the condition currently called interstitial cystitis. Part 2: Treatment].
    Aktuelle Urologie, 2008, Volume: 39, Issue:4

    Topics: Administration, Intravesical; Administration, Oral; Amitriptyline; Arginine; Botulinum Toxins, Type

2008
Paediatric painful bladder syndrome/interstitial cystitis: diagnosis and treatment.
    Drugs, 2009, Volume: 69, Issue:3

    Topics: Administration, Intravesical; Amitriptyline; Child; Cimetidine; Cystitis, Interstitial; Diet Therapy

2009
Interstitial cystitis: a primary care perspective.
    Cleveland Clinic journal of medicine, 2005, Volume: 72, Issue:8

    Topics: Amitriptyline; Cystitis, Interstitial; Disease Progression; Humans; Hydroxyzine; Primary Health Care

2005
Rational approaches to the treatment of patients with interstitial cystitis.
    Urology, 2007, Volume: 69, Issue:4 Suppl

    Topics: Administration, Intravesical; Administration, Oral; Amitriptyline; Anesthetics, Local; Combined Moda

2007
Interstitial cystitis/painful bladder syndrome.
    Urologic nursing, 2007, Volume: 27, Issue:3

    Topics: Amitriptyline; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; C

2007
[Oral therapy of interstitial cystitis].
    Der Urologe. Ausg. A, 2000, Volume: 39, Issue:6

    Topics: Administration, Oral; Amitriptyline; Analgesics; Anti-Inflammatory Agents; Cystitis, Interstitial; H

2000

Trials

1 trial available for hydroxyzine and Bladder Pain Syndrome

ArticleYear
Hydroxyzine therapy for interstitial cystitis.
    Urology, 1997, Volume: 49, Issue:5A Suppl

    Topics: Cystitis, Interstitial; Histamine H1 Antagonists; Humans; Hydroxyzine

1997

Other Studies

5 other studies available for hydroxyzine and Bladder Pain Syndrome

ArticleYear
Do medication prescription patterns follow guidelines in a cohort of women with interstitial cystitis/bladder pain syndrome?
    Neurourology and urodynamics, 2022, Volume: 41, Issue:5

    Topics: Amitriptyline; Chronic Pain; Cystitis, Interstitial; Drug Prescriptions; Female; Humans; Hydroxyzine

2022
Medications for treatment of interstitial cystitis.
    American family physician, 2015, Jan-15, Volume: 91, Issue:2

    Topics: Adult; Amitriptyline; Cimetidine; Cystitis, Interstitial; Evidence-Based Medicine; Female; Humans; H

2015
Treatment modalities, health care resource utilization, and costs in patients diagnosed with interstitial cystitis.
    American journal of obstetrics and gynecology, 2008, Volume: 199, Issue:1

    Topics: Adult; Amitriptyline; Analgesics, Non-Narcotic; Cystitis, Interstitial; Cystoscopy; Delivery of Heal

2008
Interstitial cystitis.
    Medicine and health, Rhode Island, 2009, Volume: 92, Issue:1

    Topics: Anticoagulants; Antidepressive Agents, Tricyclic; Cystitis, Interstitial; Female; Histamine H1 Antag

2009
Patient response in a screened population for interstitial cystitis.
    Comprehensive therapy, 2006,Winter, Volume: 32, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Cystitis, Interstitial; Drug Therapy, Co

2006