hydroxyzine has been researched along with Atopic Hypersensitivity in 20 studies
Hydroxyzine: A histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.
hydroxyzine : A N-alkylpiperazine that is piperzine in which the nitrogens atoms are substituted by 2-(2-hydroxyethoxy)ethyl and (4-chlorophenyl)(phenyl)methyl groups respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cetirizine, 2." | 2.67 | Compared peripheral H1 inhibiting effects of cetirizine 2 HCl and loratadine. ( Coulie, P; Ghys, L; Rihoux, JP, 1990) |
| "With cetirizine 2 HCl treatment, platelet-activating factor-acether was not detected in chamber media." | 2.66 | Inhibitory effect of oral cetirizine on in vivo antigen-induced histamine and PAF-acether release and eosinophil recruitment in human skin. ( Benveniste, J; Burtin, C; De Vos, C; Dubertret, L; Michel, L; Rihoux, JP, 1988) |
| " The hydroxyzine and cetirizine half-life and AUC0-->infinity values were significantly increased and the systemic clearance rates were significantly decreased in the presence of cimetidine." | 1.29 | Effect of the H2-receptor antagonist cimetidine, on the pharmacokinetics and pharmacodynamics of the H1-receptor antagonists hydroxyzine and cetirizine in rabbits. ( Chen, X; Simons, FE; Simons, KJ, 1994) |
| "Cetirizine also inhibited the immediate hypersensitivity reaction induced by Ascaris extract in dogs." | 1.27 | Inhibition of histamine and allergen skin wheal by cetirizine in four animal species. ( Baltes, E; De Vos, C; Gobert, J; Maleux, MR, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (45.00) | 18.7374 |
| 1990's | 9 (45.00) | 18.2507 |
| 2000's | 2 (10.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, SR | 1 |
| Wang, SS | 1 |
| Chen, X | 1 |
| Simons, FE | 2 |
| Simons, KJ | 2 |
| Choy, AC | 1 |
| Patterson, R | 1 |
| Patterson, DR | 1 |
| Grammer, LC | 1 |
| Greenberger, PA | 1 |
| McGrath, KG | 1 |
| Harris, KE | 1 |
| Demoly, P | 1 |
| Messaad, D | 1 |
| Benahmed, S | 1 |
| Sahla, H | 1 |
| Bousquet, J | 1 |
| Holstege, CP | 1 |
| Wu, J | 1 |
| Baer, AB | 1 |
| Laxenaire, MC | 1 |
| Chastel, A | 1 |
| Borgo, J | 1 |
| Kim, KM | 1 |
| Medot, A | 1 |
| Fossard, JM | 1 |
| Barlier, J | 1 |
| Varney, V | 1 |
| Gaga, M | 1 |
| Frew, AJ | 1 |
| De Vos, C | 3 |
| Kay, AB | 1 |
| Rihoux, JP | 4 |
| Ghys, L | 2 |
| Mühlethaler, K | 1 |
| Wüthrich, B | 1 |
| Shall, L | 1 |
| Thompson, DA | 1 |
| Barkley, AS | 1 |
| Millard, LG | 1 |
| Reunala, T | 2 |
| Lappalainen, P | 2 |
| Brummer-Korvenkontio, H | 2 |
| Coulie, P | 2 |
| Palosuo, T | 2 |
| Henocq, E | 1 |
| Räsänen, L | 1 |
| Barbet, JL | 1 |
| Halliwell, RE | 1 |
| Van Epps, DE | 1 |
| Kutvirt, SG | 1 |
| Potter, JW | 1 |
| Michel, L | 1 |
| Burtin, C | 1 |
| Benveniste, J | 1 |
| Dubertret, L | 1 |
| Maleux, MR | 1 |
| Baltes, E | 1 |
| Gobert, J | 1 |
| Gendreau-Reid, L | 1 |
| Griffen, D | 1 |
| Donovan, JW | 1 |
| Grolnick, M | 1 |
1 review available for hydroxyzine and Atopic Hypersensitivity
| Article | Year |
|---|---|
Immunology and treatment of mosquito bites.
Topics: Animals; Cetirizine; Culicidae; Histamine H1 Antagonists; Humans; Hydroxyzine; Hypersensitivity, Del | 1990 |
7 trials available for hydroxyzine and Atopic Hypersensitivity
| Article | Year |
|---|---|
The effect of a single oral dose of prednisolone or cetirizine on inflammatory cells infiltrating allergen-induced cutaneous late-phase reactions in atopic subjects.
Topics: Administration, Oral; Adolescent; Adult; Allergens; Cetirizine; Double-Blind Method; Histamine H1 An | 1992 |
The skin as a target organ for the investigation of antiallergic drugs: comparison between cetirizine and terfenadine.
Topics: Adolescent; Adult; Antigens; Cetirizine; Dermatitis; Double-Blind Method; Female; Histamine; Histami | 1992 |
Comparative inhibition profiles of three non-sedating antihistamines assessed by an extended Lewis model.
Topics: Adult; Analysis of Variance; Cetirizine; Cyproheptadine; Female; Histamine Antagonists; Histamine H1 | 1992 |
Cutaneous reactivity to mosquito bites: effect of cetirizine and development of anti-mosquito antibodies.
Topics: Adolescent; Adult; Aedes; Animals; Antigens; Cetirizine; Double-Blind Method; Female; Histamine; His | 1991 |
Compared peripheral H1 inhibiting effects of cetirizine 2 HCl and loratadine.
Topics: Adult; Cetirizine; Cyproheptadine; Double-Blind Method; Drug Hypersensitivity; Female; Histamine; Hi | 1990 |
Inhibitory effect of oral cetirizine on in vivo antigen-induced histamine and PAF-acether release and eosinophil recruitment in human skin.
Topics: Administration, Oral; Adolescent; Adult; Cetirizine; Eosinophils; Female; Histamine; Histamine H1 An | 1988 |
Comparison of the suppressive effect of astemizole, terfenadine, and hydroxyzine on histamine-induced wheals and flares in humans.
Topics: Adult; Astemizole; Benzhydryl Compounds; Benzimidazoles; Dose-Response Relationship, Immunologic; Do | 1986 |
12 other studies available for hydroxyzine and Atopic Hypersensitivity
| Article | Year |
|---|---|
[Suppressive effects of antihistamine on allergic skin responses].
Topics: Adult; False Negative Reactions; Female; Histamine H1 Antagonists; Humans; Hydroxyzine; Hypersensiti | 1984 |
Effect of the H2-receptor antagonist cimetidine, on the pharmacokinetics and pharmacodynamics of the H1-receptor antagonists hydroxyzine and cetirizine in rabbits.
Topics: Alanine Transaminase; Analysis of Variance; Animals; Aspartate Aminotransferases; Cetirizine; Chroma | 1994 |
Undifferentiated somatoform idiopathic anaphylaxis: nonorganic symptoms mimicking idiopathic anaphylaxis.
Topics: Adult; Albuterol; Anaphylaxis; Diagnosis, Differential; Female; Humans; Hydroxyzine; Hypersensitivit | 1995 |
Hypersensitivity to H1-antihistamines.
Topics: Chlorpheniramine; Drug Hypersensitivity; Female; Histamine H1 Antagonists; Humans; Hydroxyzine; Hype | 2000 |
Immediate hypersensitivity reaction associated with the rapid infusion of Crotalidae polyvalent immune Fab (ovine).
Topics: Adolescent; Anti-Inflammatory Agents; Antivenins; Famotidine; Histamine H1 Antagonists; Histamine H2 | 2002 |
[Prevention of complications of histamine liberation occurring after administration of anesthetic agents and adjuvants].
Topics: Adjuvants, Anesthesia; Aminocaproic Acid; Anaphylaxis; Anesthesia, General; Anesthetics; Drug Hypers | 1977 |
Does reversed-type anaphylaxis in healthy subjects mimic a real allergic reaction?
Topics: Adolescent; Adult; Anaphylaxis; Antigen-Antibody Reactions; Cell Movement; Cetirizine; Double-Blind | 1990 |
Duration of inhibition of immediate skin test reactivity by hydroxyzine hydrochloride in dogs.
Topics: Allergens; Animals; Dog Diseases; Dogs; Histamine; Hydroxyzine; Hypersensitivity, Immediate; Intrade | 1989 |
In vitro effects of cetirizine and histamine on human neutrophil function.
Topics: Cetirizine; Chemotaxis, Leukocyte; Complement C3; Histamine; Histamine H1 Antagonists; Humans; Hydro | 1987 |
Inhibition of histamine and allergen skin wheal by cetirizine in four animal species.
Topics: Allergens; Animals; Benzhydryl Compounds; Cetirizine; Clemastine; Dogs; Female; Guinea Pigs; Histami | 1987 |
Significant envenomation from a preserved rattlesnake head (in a patient with a history of immediate hypersensitivity to antivenin).
Topics: Administration, Oral; Adult; Animals; Antivenins; Crotalid Venoms; Diphenhydramine; Epinephrine; Hum | 1986 |
An investigative and clinical evaluation of dermographism.
Topics: Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Dermatitis, Atopic; Edema; Erythema; | 1970 |