Page last updated: 2024-10-28

hydroxyzine and Anesthesia

hydroxyzine has been researched along with Anesthesia in 41 studies

Hydroxyzine: A histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.
hydroxyzine : A N-alkylpiperazine that is piperzine in which the nitrogens atoms are substituted by 2-(2-hydroxyethoxy)ethyl and (4-chlorophenyl)(phenyl)methyl groups respectively.

Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-199037 (90.24)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (7.32)24.3611
2020's1 (2.44)2.80

Authors

AuthorsStudies
Aleo, E1
Picado, AL1
Abancens, BJ1
Soto Beauregard, C1
Tur Salamanca, N1
Esteban Polonios, C1
Torrejón, MJ1
Perrino, CG1
Rivas, A1
Arias, E1
Rodríguez, D1
Rivas, MÁ1
Rojo, MLR1
García, PF1
Alarcón, JR1
San Pedro de Urquiza, B1
Mistraletti, G1
Umbrello, M1
Salini, S1
Cadringher, P1
Formenti, P1
Chiumello, D1
Villa, C1
Russo, R1
Francesconi, S1
Valdambrini, F1
Bellani, G1
Palo, A1
Riccardi, F1
Ferretti, E1
Festa, M1
Gado, AM1
Taverna, M1
Pinna, C1
Barbiero, A1
Ferrari, PA1
Iapichino, G1
Chamaraux-Tran, TN1
Levy, F1
Zappaterra, M1
Goetz, J1
Goichot, B1
Steib, A1
Kobayashi, K1
Omuro, N1
Takahara, A1
BOZZA, M2
GHEZZI, R2
PONZI, A2
KLEIN, O1
FANTONI, A1
GIANNI, T1
WEYNE, F1
ROUSSEL, JL1
CORTESE, LF1
ORLANDO, E1
FRANCESCHINI, G1
DIMITRI, E1
CANE, P1
CIVAI, O1
COMINARDI, AT1
MORENA, L1
PUHALI, N1
CITRO, A1
GRADY, RW1
RICH, AL1
PFISTER, KW1
CARBONE, M2
MAZZARELLA, B2
STEINBERG, N1
HOLZ, WG1
BENSON, C1
BENSON, RC1
CHILDERS, J1
DOBKIN, AB2
ISRAEL, JS2
WOODWORTH, H1
INMON, WB1
GERRY, RG1
MILLER, CW1
SMITH, RM1
MILOWSKY, J1
SCHEER, AA1
MCCANCE, I1
MARTINS, AD1
ARANTES, JC1
CITTERIO, P1
STEFANINI, U1
CABAHUG, C1
DUFFY, FG1
FAJARDO, A1
BOZZAMARRUBINI, M1
ROSSANDA, M1
TRETOLA, L1
LEWIN-EPSTEIN, J1
AZAZ, B1
HAYWARD-BUTT, JT1
GORDON, EM1
NELSON, HB1
LUBE, J1
Silver, H1
Codesmith, AO1
Maehara, K1
Nagai, Y1
Ito, T1
Inoue, S1
Brown, LL1
Britt, BA1
Richards, AB1
Forney, RB1
Hughes, FW1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Double-blind Randomized Clinical Trial to Compare Presurgery Anxiolysis in Children Treated With Hydroxyzine Versus Non-pharmacological Intervention (Distractoria Technique Clown)[NCT03324828]Phase 4170 participants (Actual)Interventional2017-11-01Terminated (stopped due to COVID-19)
Multicentric, Single Blind, Randomized Controlled Trial on Enteral Sedation Versus Intravenous Sedation in Critically Ill High-risk ICU Patients[NCT01360346]Phase 3300 participants (Anticipated)Interventional2012-01-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for hydroxyzine and Anesthesia

ArticleYear
Evaluation of the Effect of Hydroxyzine on Preoperative Anxiety and Anesthetic Adequacy in Children: Double Blind Randomized Clinical Trial.
    BioMed research international, 2021, Volume: 2021

    Topics: Adolescent; Anesthesia; Anxiety; Child; Child, Preschool; Double-Blind Method; Female; Humans; Hydro

2021
Enteral versus intravenous approach for the sedation of critically ill patients: a randomized and controlled trial.
    Critical care (London, England), 2019, Jan-07, Volume: 23, Issue:1

    Topics: Aged; Anesthesia; Antipruritics; Central Nervous System Depressants; Critical Illness; Deep Sedation

2019

Other Studies

39 other studies available for hydroxyzine and Anesthesia

ArticleYear
Cardiac surgery and C1-inhibitor deficiency.
    Journal of cardiothoracic and vascular anesthesia, 2014, Volume: 28, Issue:6

    Topics: Aged, 80 and over; Amines; Analgesics; Anesthesia; Angioedemas, Hereditary; Antifibrinolytic Agents;

2014
The conventional antihistamine drug cyproheptadine lacks QT-interval-prolonging action in halothane-anesthetized guinea pigs: comparison with hydroxyzine.
    Journal of pharmacological sciences, 2014, Volume: 124, Issue:1

    Topics: Action Potentials; Anesthesia; Animals; Cyproheptadine; Dose-Response Relationship, Drug; Electrocar

2014
[Hydroxyzine (atarax) neuropsychic regulator for premedication in neurosurgery].
    Minerva anestesiologica, 1956, Volume: 22, Issue:9

    Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Hydroxyzine; Neurosurgery; Pain Management; Tranqui

1956
[Hydroxyzine (atarax) neuropsychic regulator for premedication in neurosurgery].
    Minerva anestesiologica, 1956, Volume: 22, Issue:9

    Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Hydroxyzine; Neurosurgery; Pain Management; Tranqui

1956
[Hydroxyzine (atarax) neuropsychic regulator for premedication in neurosurgery].
    Minerva anestesiologica, 1956, Volume: 22, Issue:9

    Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Hydroxyzine; Neurosurgery; Pain Management; Tranqui

1956
[Hydroxyzine (atarax) neuropsychic regulator for premedication in neurosurgery].
    Minerva anestesiologica, 1956, Volume: 22, Issue:9

    Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Hydroxyzine; Neurosurgery; Pain Management; Tranqui

1956
[Hydroxyzine hydrochloride as adjuvant drug in general anesthesia].
    Minerva anestesiologica, 1956, Volume: 22, Issue:9

    Topics: Anesthesia; Anesthesia, General; Anesthesia, Inhalation; Anesthesiology; Hydroxyzine; Tranquilizing

1956
[Hydroxyzine hydrochloride as adjuvant drug in general anesthesia].
    Minerva anestesiologica, 1956, Volume: 22, Issue:9

    Topics: Anesthesia; Anesthesia, General; Anesthesia, Inhalation; Anesthesiology; Hydroxyzine; Tranquilizing

1956
[Hydroxyzine hydrochloride as adjuvant drug in general anesthesia].
    Minerva anestesiologica, 1956, Volume: 22, Issue:9

    Topics: Anesthesia; Anesthesia, General; Anesthesia, Inhalation; Anesthesiology; Hydroxyzine; Tranquilizing

1956
[Hydroxyzine hydrochloride as adjuvant drug in general anesthesia].
    Minerva anestesiologica, 1956, Volume: 22, Issue:9

    Topics: Anesthesia; Anesthesia, General; Anesthesia, Inhalation; Anesthesiology; Hydroxyzine; Tranquilizing

1956
[The use of atarax in surgery and anesthesia].
    Medizinische Klinik, 1957, Sep-20, Volume: 52, Issue:38

    Topics: Anesthesia; Ethylenediamines; Humans; Hydroxyzine; Infant, Premature

1957
[Various indications for hydroxyzine in general surgery].
    Minerva medica, 1957, Sep-19, Volume: 48, Issue:75

    Topics: Anesthesia; Humans; Hydroxyzine; Tranquilizing Agents

1957
[Hydroxyzine hydrochloride (atarax) in the field of obstetrics and gynecology].
    Rivista d'ostetricia e ginecologia pratica, 1957, Volume: 39, Issue:11

    Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Female; Genital Diseases, Female; Gynecology; Human

1957
[Hydroxyzine in anesthesiology; clinical tests].
    Bruxelles medical, 1957, Dec-22, Volume: 37, Issue:51

    Topics: Anesthesia; Anesthesiology; Hydroxyzine; Tranquilizing Agents

1957
[Clinical study of the use on hydroxyzine hydrochloride in surgery].
    Minerva chirurgica, 1958, Jan-31, Volume: 13, Issue:2

    Topics: Anesthesia; Biomedical Research; Hydroxyzine; Tranquilizing Agents

1958
[Hydroxyzine chlorhydrate in anesthesia; clinical study].
    Minerva anestesiologica, 1958, Volume: 24, Issue:3

    Topics: Anesthesia; Anesthesiology; Biomedical Research; Hydroxyzine; Tranquilizing Agents

1958
[Hydroxyzine as coadjuvant in Dogliotti's segmentary peridural anesthesia in orthopedic surgery].
    Minerva anestesiologica, 1958, Volume: 24, Issue:6

    Topics: Anesthesia; Anesthesia, Epidural; Anesthesia, Spinal; Anesthesiology; Hydroxyzine; Orthopedics; Tran

1958
[Remarks on the use of hydroxyzine hydrochloride as preanesthetic].
    Minerva anestesiologica, 1958, Volume: 24, Issue:10

    Topics: Anesthesia; Anesthesiology; Humans; Hydroxyzine; Tranquilizing Agents

1958
[Hydroxyzine hydrochloride in anesthesiology].
    Minerva anestesiologica, 1958, Volume: 24, Issue:11

    Topics: Anesthesia; Anesthesiology; Hydroxyzine; Tranquilizing Agents

1958
Clinical evaluation of parenteral hydroxyzine for preoperative medication.
    Southern medical journal, 1961, Volume: 54

    Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Humans; Hydroxyzine; Pain; Pain Management; Preoper

1961
Hydroxyzine in clinical anesthesia as studied in a small hospitl.
    The Journal of the American Osteopathic Association, 1961, Volume: 60

    Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Humans; Hydroxyzine; Pain; Pain Management

1961
[On the use of hydroxyzine in anesthesia in neurosurgery].
    Minerva anestesiologica, 1959, Volume: 25

    Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Anesthesiology; Hydroxyzine; Neurosurgery; Pain Man

1959
Preoperative preparation for tonsillectomy with hydroxyzine hydrochloride in pediatric patients.
    New York state journal of medicine, 1960, Mar-01, Volume: 60

    Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Anesthesiology; Humans; Hydroxyzine; Pain Managemen

1960
The use of hydroxyzine in anesthesia for neurosurgery.
    Panminerva medica, 1960, Volume: 2

    Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Humans; Hydroxyzine; Neurosurgery; Neurosurgical Pr

1960
Hydroxyzine-meperidine analgesia and neonatal response.
    American journal of obstetrics and gynecology, 1962, Jul-01, Volume: 84

    Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Anesthesia, Obstetrical; Fetus; Humans; Hydroxyzine

1962
Hydroxyzine in labor and delivery.
    The Journal of the Kentucky Medical Association, 1961, Volume: 59

    Topics: Anesthesia; Anesthesia, Obstetrical; Delivery, Obstetric; Female; Humans; Hydroxyzine; Labor, Obstet

1961
The effect of SA 97, perphenazine, and hydroxyzine on epinephrine-induced cardiac arrhythmias during methoxyflurane anaesthesia in dogs.
    Canadian Anaesthetists' Society journal, 1962, Volume: 9

    Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Animals; Anti-Allergic Agents; Arrhythmias, Cardiac

1962
The antisialogoue effect of hydroxyzine, thiethylperazine, and n-p-chloro-benzylhydryl-n'-methyl homopiperazine (SA 97).
    Canadian Anaesthetists' Society journal, 1962, Volume: 9

    Topics: Anesthesia; Anesthesia, General; Anesthesiology; Anti-Allergic Agents; Antiemetics; Histamine H1 Ant

1962
A STUDY OF THE EFFECT OF HYDROXYZINE HYDROCHLORIDE ON LABOR AND DELIVERY.
    American journal of obstetrics and gynecology, 1963, Aug-01, Volume: 86

    Topics: Anesthesia; Anesthesia, Obstetrical; Delivery, Obstetric; Female; Humans; Hydroxyzine; Labor, Obstet

1963
TOTAL EXTRACTION FOR IMMEDIATE DENTURES UNDER LOCAL ANESTHESIA SUPPLEMENTED BY INTRAVENOUS TRANQUILIZERS.
    Journal of oral surgery, anesthesia, and hospital dental service, 1963, Volume: 21

    Topics: Anesthesia; Anesthesia, Dental; Anesthesia, Local; Dental Prosthesis; Dentures; Humans; Hydroxyzine;

1963
CURRENT ISSUES IN PEDIATRIC ANESTHESIA.
    American journal of surgery, 1964, Volume: 107

    Topics: Adolescent; Anesthesia; Anesthesia, Endotracheal; Anesthesia, Inhalation; Anesthesiology; Blood Pres

1964
ANESTHESIA FOR STAPES SURGERY. A REPORT OF 1,000 CONSECUTIVE, UNSELECTED PATIENTS.
    Archives of otolaryngology (Chicago, Ill. : 1960), 1964, Volume: 80

    Topics: Analgesia; Anesthesia; Anesthesia, Local; Barbiturates; Humans; Hydroxyzine; Lidocaine; Meperidine;

1964
STUDIES OF POTENTIATION OF HEXOBARBITONE INFUSED INTRAVENOUSLY.
    Archives internationales de pharmacodynamie et de therapie, 1964, Mar-01, Volume: 148

    Topics: Anesthesia; Anesthesia, Intravenous; Anti-Anxiety Agents; Anticonvulsants; Atropine; Benactyzine; Ca

1964
[RESERPINE IN LABOR].
    Hospital (Rio de Janeiro, Brazil), 1964, Volume: 65

    Topics: Adjuvants, Anesthesia; Anesthesia; Anesthesia, Obstetrical; Female; Glutethimide; Humans; Hydroxyzin

1964
[EXPERIENCE WITH AN ASSOCIATION OF AN ANALGESIC AND TRANQUILIZING AGENT IN LABOR].
    Rivista d'ostetricia e ginecologia pratica, 1964, Volume: 46

    Topics: Analgesics; Anesthesia; Anesthesia, Obstetrical; Female; Humans; Hydroxyzine; Hypnotics and Sedative

1964
HYDROXYZINE AS ADJUNCT TO ANESTHESIA.
    Current therapeutic research, clinical and experimental, 1964, Volume: 6

    Topics: Anesthesia; Anesthesia, General; Anesthesia, Spinal; Anesthesiology; Atropine; Biomedical Research;

1964
THE ROLE OF ARTIFICIAL HYPERVENTILATION IN THE CONTROL OF BRAIN TENSION DURING NEUROSURGICAL OPERATIONS.
    British journal of anaesthesia, 1964, Volume: 36

    Topics: Anesthesia; Anesthesia, Endotracheal; Brain; Brain Diseases; Brain Neoplasms; Humans; Hydroxyzine; H

1964
HYDROXYZINE HYDROCHLORIDE AS PREMEDICATION FOR AMBULATORY ORAL SURGERY PATIENTS.
    Journal of oral surgery, anesthesia, and hospital dental service, 1964, Volume: 22

    Topics: Adolescent; Alveolectomy; Anesthesia; Anesthesia, Local; Apicoectomy; Biomedical Research; Blood Pre

1964
HYDROXYZINE HYDROCHLORIDE. MEDICATION PRIOR TO ANESTHESIA.
    Rocky Mountain medical journal, 1964, Volume: 61

    Topics: Anesthesia; Anesthesia, Conduction; Anesthesia, General; Anesthesiology; Biomedical Research; Humans

1964
A DOUBLE BLIND STUDY OF THE EFFECT OF TRANQUILIZERS DURING LABOR.
    American journal of obstetrics and gynecology, 1965, Jun-01, Volume: 92

    Topics: Anesthesia; Anesthesia, Obstetrical; Biomedical Research; Double-Blind Method; Drug Therapy; Female;

1965
[Clinical experiences with the problem of the reduction of pain and the shortening of labor with sanaestin, sanaestin/sparcotin, and atarax].
    Das Deutsche Gesundheitswesen, 1959, Oct-15, Volume: 14

    Topics: Anesthesia; Anesthesia, Obstetrical; Female; Humans; Hydroxyzine; Labor, Obstetric; Pain; Pregnancy

1959
Anesthesia for outpatient head and neck aesthetic surgery.
    Annals of plastic surgery, 1980, Volume: 5, Issue:6

    Topics: Ambulatory Surgical Procedures; Anesthesia; Diazepam; Esthetics; Head; Humans; Hydroxyzine; Lorazepa

1980
[Effect of acupuncture on postoperative upper abdominal pain].
    Masui. The Japanese journal of anesthesiology, 1975, Volume: 24, Issue:2

    Topics: Abdomen; Acupuncture Therapy; Adult; Aged; Anesthesia; Female; Humans; Hydroxyzine; Male; Middle Age

1975
Malignant hyperthermia.
    Southern medical journal, 1974, Volume: 67, Issue:7

    Topics: Anesthesia; Atropine; Bicarbonates; Creatine Kinase; Cyclopropanes; Female; Halothane; Humans; Hydro

1974
Enhancement of the depressant action of hexobarbital by tranquilizers in mice.
    Life sciences, 1965, Volume: 4, Issue:10

    Topics: Anesthesia; Animals; Arousal; Biological Assay; Chlorpromazine; Drug Synergism; Hexobarbital; Hydrox

1965