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hydroxyzine and Anaphylactic Reaction

hydroxyzine has been researched along with Anaphylactic Reaction in 18 studies

Hydroxyzine: A histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.
hydroxyzine : A N-alkylpiperazine that is piperzine in which the nitrogens atoms are substituted by 2-(2-hydroxyethoxy)ethyl and (4-chlorophenyl)(phenyl)methyl groups respectively.

Research Excerpts

ExcerptRelevanceReference
"Anaphylactic reactions are very rare with hydroxyzine used in premedication for anesthesia in regard to the large prescription of the drug."5.35Anaphylactic reaction to hydroxyzine in an anesthetized patient. ( Boulay-Malinovsky, C; Charles, A; Gallet, A; Lavaud, F; Malinovsky, JM; Mertes, PM, 2009)
" and intracerebroventricular pentobarbital-induced sedation and alcohol-induced ataxia models."3.76Characterization of anti-inflammatory properties and evidence for no sedation liability for the novel antihistamine SUN-1334H. ( Bagad, AS; Bahekar, PC; Chidrewar, GU; Mandhane, SN; Mehetre, SV; Pawar, CA; Rajamannar, T; Rao, CT; Shah, JH, 2010)
"The histamine releasing potential of atracurium was assessed by testing skin reactivity in ten patients who had previously suffered from a preanaesthetic anaphylactoid accident, but in whom the diagnosis of anaphylaxis had not been confirmed."3.67[The histaminic and anaphylactic risks of atracurium]. ( Laxenaire, MC; Moneret-Vautrin, DA; Widmer, S, 1985)
"Anaphylactic reactions are very rare with hydroxyzine used in premedication for anesthesia in regard to the large prescription of the drug."1.35Anaphylactic reaction to hydroxyzine in an anesthetized patient. ( Boulay-Malinovsky, C; Charles, A; Gallet, A; Lavaud, F; Malinovsky, JM; Mertes, PM, 2009)
"The danger of the anaphylactoid reactions which occur during pediatric general anesthesia leads the authors to use a specific antihistaminic premedication."1.27A specific antihistaminic premedication anti H1 anti H2 for pediatric anesthesia. ( Cupa, M; Fournier, JL; Khenifer, L; Le Mapihan, Y; Pierrot, M, 1984)
"There was no evidence of causes for the anaphylactic reactions over a two and a half year period."1.27Life-threatening idiopathic anaphylaxis associated with hyperimmunoglobulinemia E. ( Greenberger, PA, 1984)
"In this group there was not a single anaphylactic reaction."1.27Repeat chemonucleolysis. ( Sutton, JC, 1986)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19909 (50.00)18.7374
1990's6 (33.33)18.2507
2000's1 (5.56)29.6817
2010's2 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ishii, K1
Miyoshi, H1
Akiyama, D1
Makita, T1
Sumikawa, K1
Murata, H1
Hara, T1
Mandhane, SN1
Shah, JH1
Bahekar, PC1
Mehetre, SV1
Pawar, CA1
Bagad, AS1
Chidrewar, GU1
Rao, CT1
Rajamannar, T1
Charles, A1
Lavaud, F1
Gallet, A1
Boulay-Malinovsky, C1
Mertes, PM1
Malinovsky, JM1
Le Mapihan, Y1
Pierrot, M1
Khenifer, L1
Fournier, JL1
Cupa, M1
Greenberger, PA3
Choy, AC1
Patterson, R3
Patterson, DR1
Grammer, LC1
McGrath, KG1
Harris, KE1
Lieberman, P1
Nakao, M1
Nakatani, K1
Suyama, H1
Maekawa, T1
Nakagawa, M1
Hanaki, C1
Kawaguchi, R1
Ditto, AM1
Krasnick, J1
Kelly, KJ1
McGrath, K1
Laxenaire, MC2
Chastel, A1
Borgo, J1
Kim, KM1
Medot, A1
Fossard, JM1
Barlier, J1
Bertrand, PR1
Soyer, PM1
Rouleau, PJ1
Alison, DP1
Billardon, MJ1
Henocq, E1
Rihoux, JP1
Grilliat, JP1
Moneret-Vautrin, DA1
Widmer, S1
Wagner, W1
Sutton, JC1
Artus, M1
Hollocou, B1
Bodin, JM1
Noury, D1
Roumeas, J1
Malledant, Y1
Launois, B1
Saint Marc, C1
Cîrstea, M1
Boroş, I1
Suhaciu, G1

Reviews

1 review available for hydroxyzine and Anaphylactic Reaction

ArticleYear
Idiopathic anaphylaxis: a purely internal reaction.
    Hospital practice (1995), 1996, Jul-15, Volume: 31, Issue:7

    Topics: Albuterol; Anaphylaxis; Exercise; Food; Glucocorticoids; Histamine H1 Antagonists; Humans; Hydroxyzi

1996

Trials

1 trial available for hydroxyzine and Anaphylactic Reaction

ArticleYear
Comparative randomized double-blind study of hydroxyzine versus placebo as premedication before injection of iodinated contrast media.
    Radiology, 1992, Volume: 184, Issue:2

    Topics: Aged; Anaphylaxis; Double-Blind Method; Female; Humans; Hydroxyzine; Ioxaglic Acid; Male; Middle Age

1992

Other Studies

16 other studies available for hydroxyzine and Anaphylactic Reaction

ArticleYear
Anesthetic management of patients with systemic mastocytosis.
    Journal of clinical anesthesia, 2018, Volume: 50

    Topics: Adenomatous Polyposis Coli; Adult; Anaphylaxis; Anesthesia, General; Anesthetics; Colectomy; Epineph

2018
Characterization of anti-inflammatory properties and evidence for no sedation liability for the novel antihistamine SUN-1334H.
    International archives of allergy and immunology, 2010, Volume: 151, Issue:1

    Topics: Acetates; Alcohols; Anaphylaxis; Animals; Anti-Inflammatory Agents, Non-Steroidal; Ataxia; Cetirizin

2010
Anaphylactic reaction to hydroxyzine in an anesthetized patient.
    European annals of allergy and clinical immunology, 2009, Volume: 41, Issue:4

    Topics: Anaphylaxis; Drug Hypersensitivity; Female; Histamine H1 Antagonists; Humans; Hydroxyzine; Intraderm

2009
A specific antihistaminic premedication anti H1 anti H2 for pediatric anesthesia.
    Acta anaesthesiologica Belgica, 1984, Volume: 35 Suppl

    Topics: Anaphylaxis; Anesthesia, General; Child; Child, Preschool; Cimetidine; Drug Therapy, Combination; Fe

1984
Life-threatening idiopathic anaphylaxis associated with hyperimmunoglobulinemia E.
    The American journal of medicine, 1984, Volume: 76, Issue:3

    Topics: Anaphylaxis; Cimetidine; Coronary Disease; Diphenhydramine; Humans; Hydroxyzine; Hypergammaglobuline

1984
Undifferentiated somatoform idiopathic anaphylaxis: nonorganic symptoms mimicking idiopathic anaphylaxis.
    The Journal of allergy and clinical immunology, 1995, Volume: 96, Issue:6 Pt 1

    Topics: Adult; Albuterol; Anaphylaxis; Diagnosis, Differential; Female; Humans; Hydroxyzine; Hypersensitivit

1995
[A case of life-threatening anaphylactoid reaction caused by povidone-iodine].
    Masui. The Japanese journal of anesthesiology, 1997, Volume: 46, Issue:1

    Topics: Anaphylaxis; Anesthesia, General; Coronary Artery Bypass; Famotidine; Histamine H1 Antagonists; Hist

1997
Pediatric idiopathic anaphylaxis: experience with 22 patients.
    The Journal of allergy and clinical immunology, 1997, Volume: 100, Issue:3

    Topics: Adolescent; Adrenergic beta-Agonists; Adult; Albuterol; Anaphylaxis; Anti-Inflammatory Agents; Child

1997
[Prevention of complications of histamine liberation occurring after administration of anesthetic agents and adjuvants].
    Annales de l'anesthesiologie francaise, 1977, Volume: 18, Issue:7-8

    Topics: Adjuvants, Anesthesia; Aminocaproic Acid; Anaphylaxis; Anesthesia, General; Anesthetics; Drug Hypers

1977
Does reversed-type anaphylaxis in healthy subjects mimic a real allergic reaction?
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1990, Volume: 20, Issue:3

    Topics: Adolescent; Adult; Anaphylaxis; Antigen-Antibody Reactions; Cell Movement; Cetirizine; Double-Blind

1990
[Role of the autonomic nervous system in the modulation of anaphylaxis].
    Annales francaises d'anesthesie et de reanimation, 1985, Volume: 4, Issue:2

    Topics: Anaphylaxis; Autonomic Nervous System; Histamine; Histamine Release; Humans; Hydroxyzine; Isoprotere

1985
[The histaminic and anaphylactic risks of atracurium].
    Annales francaises d'anesthesie et de reanimation, 1985, Volume: 4, Issue:6

    Topics: Anaphylaxis; Atracurium; Dose-Response Relationship, Drug; Histamine Release; Humans; Hydroxyzine; I

1985
Exercise-induced allergic syndromes on the increase.
    Cleveland Clinic journal of medicine, 1989, Volume: 56, Issue:7

    Topics: Adolescent; Adult; Albuterol; Anaphylaxis; Asthma; Asthma, Exercise-Induced; Beclomethasone; Exercis

1989
Repeat chemonucleolysis.
    Clinical orthopaedics and related research, 1986, Issue:206

    Topics: Adolescent; Adult; Anaphylaxis; Chymopapain; Cimetidine; Female; Follow-Up Studies; Histamine H1 Ant

1986
[Anaphylactic shock during surgical treatment of hepatic hydatidosis].
    Cahiers d'anesthesiologie, 1985, Volume: 33, Issue:7

    Topics: Adult; Aminocaproic Acid; Anaphylaxis; Drug Therapy, Combination; Echinococcosis, Hepatic; Female; H

1985
Influence of the drugs on the immuno-allergic reactivity. IV. The action of tranquillizers on passive anaphylaxis in guinea-pig.
    Revue roumaine de morphologie et de physiologie, 1974, Volume: 20, Issue:1

    Topics: Anaphylaxis; Animals; Chlordiazepoxide; Drug Evaluation, Preclinical; Guinea Pigs; Histamine; Histam

1974