hydroxyurea has been researched along with Tricuspid Incompetence in 10 studies
Excerpt | Relevance | Reference |
---|---|---|
" It appears to be a complication of chronic hemolysis, is resistant to hydroxyurea therapy, and confers a high risk of death." | 3.72 | Pulmonary hypertension as a risk factor for death in patients with sickle cell disease. ( Blackwelder, WC; Brown, B; Castro, O; Coles, WA; Ernst, I; Gladwin, MT; Hunter, LA; Jison, ML; Minter, K; Nichols, JS; Ognibene, FP; Plehn, JF; Rodgers, GP; Sachdev, V; Schechter, AN; Shizukuda, Y, 2004) |
" Accordingly, we conclude that clinical trials in SCD designed to increase the bioavailability of NO or association studies in which SCD clinical manifestations are related to plasma hemoglobin via its surrogates should be viewed with caution." | 2.46 | Pulmonary hypertension and nitric oxide depletion in sickle cell disease. ( Bunn, HF; Dover, GJ; Hebbel, RP; Nathan, DG; Platt, OS; Rosse, WF; Ware, RE, 2010) |
"Hydroxyurea-treated patients had higher apelin levels than untreated ones (P=0." | 1.43 | Serum apelin as a novel non-invasive marker for subclinical cardiopulmonary complications in children and adolescents with sickle cell disease. ( Elbarbary, NS; Fahmy, E; Ismail, EA; Roushdy, A, 2016) |
"Pulmonary hypertension is common among Nigerian SCD patients." | 1.35 | Prevalence and risk factors for pulmonary artery systolic hypertension among sickle cell disease patients in Nigeria. ( Akpanpe, P; Aliyu, N; Aliyu, ZY; Attah, E; Babadoko, A; Gladwin, MT; Gordeuk, V; Kato, GJ; Mamman, AI; Mendelsohn, L; Sachdev, V; Suleiman, Y; Yusuf, J, 2008) |
"Despite treatment for pulmonary hypertension and provision of respiratory support, the patient died." | 1.33 | Pulmonary hypertension in a child with juvenile myelomonocytic leukemia secondary to pulmonary leukemic cell infiltration. ( Alioglu, B; Demirhan, B; Erbay, A; Ozbek, N; Ozyurek, E; Varan, B, 2006) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 4 (40.00) | 29.6817 |
2010's | 5 (50.00) | 24.3611 |
2020's | 1 (10.00) | 2.80 |
Authors | Studies |
---|---|
Rai, P | 1 |
Joshi, VM | 1 |
Goldberg, JF | 1 |
Yates, AM | 1 |
Okhomina, VI | 1 |
Penkert, R | 1 |
Ataga, KI | 2 |
Kang, G | 1 |
Hankins, JS | 1 |
Jain, S | 1 |
Kapetanaki, MG | 1 |
Raghavachari, N | 1 |
Woodhouse, K | 1 |
Yu, G | 1 |
Barge, S | 1 |
Coronnello, C | 1 |
Benos, PV | 1 |
Kato, GJ | 3 |
Kaminski, N | 1 |
Gladwin, MT | 5 |
Desai, PC | 1 |
May, RC | 1 |
Jones, SK | 1 |
Strayhorn, D | 1 |
Caughey, M | 1 |
Hinderliter, A | 1 |
Elbarbary, NS | 1 |
Ismail, EA | 1 |
Roushdy, A | 1 |
Fahmy, E | 1 |
Gordeuk, VR | 1 |
Campbell, A | 1 |
Rana, S | 1 |
Nouraie, M | 1 |
Niu, X | 1 |
Minniti, CP | 1 |
Sable, C | 1 |
Darbari, D | 1 |
Dham, N | 1 |
Onyekwere, O | 1 |
Ammosova, T | 1 |
Nekhai, S | 1 |
Castro, OL | 1 |
Bunn, HF | 1 |
Nathan, DG | 1 |
Dover, GJ | 1 |
Hebbel, RP | 1 |
Platt, OS | 1 |
Rosse, WF | 1 |
Ware, RE | 1 |
Sachdev, V | 2 |
Jison, ML | 1 |
Shizukuda, Y | 1 |
Plehn, JF | 1 |
Minter, K | 1 |
Brown, B | 1 |
Coles, WA | 1 |
Nichols, JS | 1 |
Ernst, I | 1 |
Hunter, LA | 1 |
Blackwelder, WC | 1 |
Schechter, AN | 1 |
Rodgers, GP | 1 |
Castro, O | 1 |
Ognibene, FP | 1 |
Alioglu, B | 1 |
Demirhan, B | 1 |
Ozyurek, E | 1 |
Varan, B | 1 |
Erbay, A | 1 |
Ozbek, N | 1 |
Aliyu, ZY | 1 |
Gordeuk, V | 1 |
Babadoko, A | 1 |
Mamman, AI | 1 |
Akpanpe, P | 1 |
Attah, E | 1 |
Suleiman, Y | 1 |
Aliyu, N | 1 |
Yusuf, J | 1 |
Mendelsohn, L | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
A Substudy of the CADRE Study: Determination of Clinical Markers in Patients With Extreme Sickle Cell Disease Phenotype[NCT03352986] | 300 participants (Anticipated) | Observational | 2017-05-15 | Recruiting | |||
Macrolide Therapy to Improve Forced Expiratory Volume in 1 Second in Adults With Sickle Cell Disease: a Feasibility Trial[NCT02960503] | Phase 1/Phase 2 | 0 participants (Actual) | Interventional | 2016-09-30 | Withdrawn (stopped due to Key personnel moved to new location. Therefore, we had insufficient resources to initiate the trial.) | ||
Long-Term, Open-Label, Multicenter, Extension Study of Bosentan in Patients With Pulmonary Hypertension Associated With Sickle Cell Disease Completing a Double-Blind ASSET Study (AC-052-368 or AC 052-369)[NCT00360087] | Phase 3 | 236 participants | Interventional | 2006-03-31 | Terminated (stopped due to Slow enrollment) | ||
Role of Nitric Oxide Scavenging by Plasma Hemoglobin and Identification of Hemolysis-Associated Pulmonary Hypertension in Malaria[NCT00527163] | 103 participants (Actual) | Observational | 2007-09-04 | Completed | |||
Serum Brain Natriuretic Peptide Levels and Its Correlation With Echocardiographic Measurements Suggestive of Pulmonary Hypertension in Pediatric Patients With Sickle Cell Disease[NCT01023451] | 21 participants (Actual) | Observational | 2009-12-31 | Completed | |||
Iron-mediated Vascular Disease in Sickle Cell Disease.[NCT01239901] | 150 participants (Actual) | Observational | 2009-12-31 | Completed | |||
Erythrocyte Glutamine Level Relation to Pulmonary Hypertension Risk in Beta Thalassemia Major Children in Assiut University Children Hospital[NCT03133169] | 80 participants (Actual) | Observational | 2017-06-01 | Completed | |||
Heart, Arteries and Sikle Cell Disease, a Multicentric Cohort of Cardiovascular Complications in Subsaharan Africa[NCT03114137] | 4,500 participants (Anticipated) | Observational [Patient Registry] | 2012-03-31 | Recruiting | |||
An Evaluation of Tricuspid Regurgitant Jet Velocity as an Independent Marker for Mortality in Patients With Sickle Cell Anemia: A Retrospective Data Review[NCT01783093] | 209 participants (Actual) | Observational | 2009-12-31 | Completed | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
1 review available for hydroxyurea and Tricuspid Incompetence
Article | Year |
---|---|
Pulmonary hypertension and nitric oxide depletion in sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Animals; Child; Clinical Trials as Topic; Disease Models, Animal; Echoca | 2010 |
9 other studies available for hydroxyurea and Tricuspid Incompetence
Article | Year |
---|---|
Longitudinal effect of disease-modifying therapy on tricuspid regurgitant velocity in children with sickle cell anemia.
Topics: Adult; Anemia, Sickle Cell; Child; Humans; Hydroxyurea; Prospective Studies; Thalassemia; Tricuspid | 2021 |
Expression of regulatory platelet microRNAs in patients with sickle cell disease.
Topics: Adult; Aged; Anemia, Sickle Cell; Blood Platelets; Cell Line; Chromosomes, Human, Pair 14; Computati | 2013 |
Longitudinal study of echocardiography-derived tricuspid regurgitant jet velocity in sickle cell disease.
Topics: Adult; Aged; Anemia, Sickle Cell; Antisickling Agents; Echocardiography; Female; Humans; Hydroxyurea | 2013 |
Revisiting the hyperhemolysis paradigm.
Topics: Anemia, Sickle Cell; Animals; Blood Transfusion; Brachial Artery; Cyclic N-Oxides; Female; Free Radi | 2015 |
Serum apelin as a novel non-invasive marker for subclinical cardiopulmonary complications in children and adolescents with sickle cell disease.
Topics: Adolescent; Anemia, Sickle Cell; Antisickling Agents; Apelin; Arterial Pressure; Bilirubin; Biomarke | 2016 |
Relationship of erythropoietin, fetal hemoglobin, and hydroxyurea treatment to tricuspid regurgitation velocity in children with sickle cell disease.
Topics: Adolescent; Adult; Anemia, Sickle Cell; Antisickling Agents; Child; Child, Preschool; Erythropoietin | 2009 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Blood Pressure; Cause of Death; Drug Resistance; Ec | 2004 |
Pulmonary hypertension in a child with juvenile myelomonocytic leukemia secondary to pulmonary leukemic cell infiltration.
Topics: Anti-Bacterial Agents; Child, Preschool; Combined Modality Therapy; Diagnostic Errors; Fatal Outcome | 2006 |
Prevalence and risk factors for pulmonary artery systolic hypertension among sickle cell disease patients in Nigeria.
Topics: Adolescent; Adult; Anemia, Sickle Cell; Case-Control Studies; Female; Humans; Hydroxyurea; Hypertens | 2008 |