hydroxyurea and Sterility, Male
hydroxyurea has been researched along with Sterility, Male in 8 studies
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
"Two experiments were conducted to determine: 1) whether the adult male transgenic sickle cell mouse (Tg58 x Tg98; TSCM), exhibits the patterns of reproductive endpoints (hypogonadism) characteristic of men with sickle cell disease (SCD) and 2) whether hydroxyurea (HU) exacerbates this condition." | 3.75 | Adverse effects of a clinically relevant dose of hydroxyurea used for the treatment of sickle cell disease on male fertility endpoints. ( Aguinaga, MP; Archibong, AE; Bourne, P; Brooks, CM; Bruce, D; Hills, ER; Jones, KM; Niaz, MS; Rice, VM; Roberson, SI, 2009) |
"Treatment with hydroxyurea is usually considered for patients with recurrent vaso-occlusive events, but additional indications for treatment may include laboratory markers of disease severity and evidence of chronic organ dysfunction." | 2.45 | Advances in the use of hydroxyurea. ( Aygun, B; Ware, RE, 2009) |
"Recent progress in the treatment of sickle cell disease, in particular the use of hydroxyurea, has considerably modified the prognosis of this disease." | 1.35 | Influence of sickle cell disease and treatment with hydroxyurea on sperm parameters and fertility of human males. ( Ancel, PY; Bachir, D; Berthaut, I; de Larouziere, V; Galactéros, F; Girot, R; Guignedoux, G; Jouannet, P; Kirsch-Noir, F; Kunstmann, JM; Levy, L; Mandelbaum, J; Ravel, C, 2008) |
Research
Studies (8)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 4 (50.00) | 29.6817 |
2010's | 3 (37.50) | 24.3611 |
2020's | 1 (12.50) | 2.80 |
Authors
Authors | Studies |
---|---|
Joseph, L | 1 |
Jean, C | 1 |
Manceau, S | 1 |
Chalas, C | 1 |
Arnaud, C | 1 |
Kamdem, A | 1 |
Pondarré, C | 1 |
Habibi, A | 1 |
Bernaudin, F | 1 |
Allali, S | 1 |
de Montalembert, M | 1 |
Boutonnat-Faucher, B | 1 |
Arlet, JB | 1 |
Koehl, B | 1 |
Cavazzana, M | 1 |
Ribeil, JA | 1 |
Lionnet, F | 1 |
Berthaut, I | 2 |
Brousse, V | 1 |
Tohamy, HG | 1 |
Gad El-Karim, DR | 1 |
El-Sayed, YS | 1 |
DeBaun, MR | 1 |
Smith-Whitley, K | 1 |
Guignedoux, G | 1 |
Kirsch-Noir, F | 1 |
de Larouziere, V | 1 |
Ravel, C | 1 |
Bachir, D | 1 |
Galactéros, F | 1 |
Ancel, PY | 1 |
Kunstmann, JM | 1 |
Levy, L | 1 |
Jouannet, P | 1 |
Girot, R | 1 |
Mandelbaum, J | 1 |
Lukusa, AK | 1 |
Vermylen, C | 1 |
Jones, KM | 1 |
Niaz, MS | 1 |
Brooks, CM | 1 |
Roberson, SI | 1 |
Aguinaga, MP | 1 |
Hills, ER | 1 |
Rice, VM | 1 |
Bourne, P | 1 |
Bruce, D | 1 |
Archibong, AE | 1 |
Ware, RE | 1 |
Aygun, B | 1 |
Clinical Trials (1)
Trial Overview
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Evaluation of Sickle Cell Liver Disease[NCT01950429] | 42 participants (Actual) | Observational | 2013-10-16 | Completed | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
Reviews
3 reviews available for hydroxyurea and Sterility, Male
Article | Year |
---|---|
Hydroxyurea therapy contributes to infertility in adult men with sickle cell disease: a review.
Topics: Anemia, Sickle Cell; Animals; Antisickling Agents; Humans; Hydroxyurea; Hypogonadism; Infertility, M | 2014 |
Reproductive issues in sickle cell disease.
Topics: Anemia, Sickle Cell; Antisickling Agents; Female; Fertility; Humans; Hydroxyurea; Infertility, Femal | 2014 |
Advances in the use of hydroxyurea.
Topics: Adult; Anemia, Sickle Cell; Animals; Arterial Occlusive Diseases; Bone Marrow Diseases; Child; Clini | 2009 |
Other Studies
5 other studies available for hydroxyurea and Sterility, Male
Article | Year |
---|---|
Effect of hydroxyurea exposure before puberty on sperm parameters in males with sickle cell disease.
Topics: Acute Chest Syndrome; Adolescent; Age Factors; Anemia, Sickle Cell; Antisickling Agents; Arterial Oc | 2021 |
Attenuation potentials of royal jelly against hydroxyurea-induced infertility through inhibiting oxidation and release of pro-inflammatory cytokines in male rats.
Topics: Animals; Antioxidants; Catalase; Cytokines; Fatty Acids; Hydroxyurea; Infertility, Male; Male; Oxida | 2019 |
Influence of sickle cell disease and treatment with hydroxyurea on sperm parameters and fertility of human males.
Topics: Adolescent; Adult; Anemia, Sickle Cell; Fertility; Heterozygote; Homozygote; Humans; Hydroxyurea; In | 2008 |
Use of hydroxyurea from childhood to adult age in sickle cell disease: semen analysis.
Topics: Adolescent; Adult; Anemia, Sickle Cell; Child; Fertility; Humans; Hydroxyurea; Infertility, Male; Ma | 2008 |
Adverse effects of a clinically relevant dose of hydroxyurea used for the treatment of sickle cell disease on male fertility endpoints.
Topics: Anemia, Sickle Cell; Animals; Antisickling Agents; Disease Models, Animal; Hydroxyurea; Hypogonadism | 2009 |