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hydroxyurea and Skin Ulcer

hydroxyurea has been researched along with Skin Ulcer in 19 studies

Skin Ulcer: An ULCER of the skin and underlying tissues.

Research Excerpts

ExcerptRelevanceReference
" She had a history of polycythemia vera and had been treated with a daily dose of 500mg hydroxyurea (HU) for six years."7.72Huge post-operative ulcer following hydroxyurea therapy in a patient with polycythemia vera. ( Iwata, K; Nakano, M; Ogawa, H; Ogura, S; Seki, K; Tasaka, T; Yokota, K, 2003)
"Hydroxyurea (HU) is usually a well-tolerated antineoplastic agent, which is commonly used in the treatment of myeloproliferative disorders."7.71[Hydroxyurea-induced leg ulcers in patients with chronic myeloproliferative disorders]. ( Olesen, LH; Pedersen, BB, 2001)
"Hydroxyurea (HU) is an established chemotherapeutic agent in the treatment of myeloproliferative disorders (MPD) including chronic myelogenous leukemia (CML), polycythemia vera and essential thrombocythemia (ET)."7.70Cutaneous ulcers associated with hydroxyurea therapy in myeloproliferative disorders. ( Cohen, P; Cortes, J; Kantarjian, H; Markowitz, A; O'Brien, S; Ravandi-Kashani, F; Talpaz, M, 1999)
" Pregnancy is a high-risk situation for the mother and child The efficacy and safety of hydroxyurea and long-term blood transfusions in adults with sickle cell disease are currently under investigation."4.84[New issues in adult sickle sell disease]. ( Girot, R; Lionnet, F; Stankovic, K, 2008)
" She had a history of polycythemia vera and had been treated with a daily dose of 500mg hydroxyurea (HU) for six years."3.72Huge post-operative ulcer following hydroxyurea therapy in a patient with polycythemia vera. ( Iwata, K; Nakano, M; Ogawa, H; Ogura, S; Seki, K; Tasaka, T; Yokota, K, 2003)
"Hydroxyurea (HU) is usually a well-tolerated antineoplastic agent, which is commonly used in the treatment of myeloproliferative disorders."3.71[Hydroxyurea-induced leg ulcers in patients with chronic myeloproliferative disorders]. ( Olesen, LH; Pedersen, BB, 2001)
"Hydroxyurea (HU) is an established chemotherapeutic agent in the treatment of myeloproliferative disorders (MPD) including chronic myelogenous leukemia (CML), polycythemia vera and essential thrombocythemia (ET)."3.70Cutaneous ulcers associated with hydroxyurea therapy in myeloproliferative disorders. ( Cohen, P; Cortes, J; Kantarjian, H; Markowitz, A; O'Brien, S; Ravandi-Kashani, F; Talpaz, M, 1999)
"The unusual appearance of extensive skin ulcerations was observed in 17 patients with chronic myelogenous leukemia on continuous chemotherapy with hydroxyurea."3.67Unusual dermatologic toxicity of long-term therapy with hydroxyurea in chronic myelogenous leukemia. ( Alimena, G; Carlesimo, OA; Gastaldi, R; Mandelli, F; Montefusco, E; Valesini, G, 1986)
"Hydroxyurea is an antitumoral drug mainly used in the treatment of Philadelphia chromosome-negative myeloproliferative syndromes and sickle-cell disease."2.49Cutaneous ulcers associated with hydroxyurea therapy. ( Barbanera, S; Dini, V; Quattrone, F; Romanelli, M; Zerbinati, N, 2013)
"Venous thrombosis is more frequent in PV than in ET; superficial or deep venous thromboses are seen."2.41[What vascular events suggest a myeloproliferative disorder?]. ( Caulier-Leleu, MT; Hachulla, E; Pasturel-Michon, U; Rose, C; Trillot, N, 2000)
" However, no epidemiologic information about the occurrence of the most clinically significant HU-associated adverse events is yet available."1.38Hydroxyurea-related toxicity in 3,411 patients with Ph'-negative MPN. ( Antonioli, E; Baccarani, M; Barbui, T; Bertozzi, I; Bosi, A; Cacciola, E; Cacciola, R; Cazzola, M; De Stefano, V; Elli, E; Finazzi, G; Finazzi, M; Guglielmelli, P; Luigia Randi, M; Martinelli, V; Passamonti, F; Pieri, L; Pogliani, E; Rambaldi, A; Rodeghiero, F; Rossi, E; Ruggeri, M; Rumi, E; Vannucchi, AM; Vianelli, N; Za, T, 2012)
"Hydroxyurea is a usually well-tolerated cytostatic agent, but its side effects include cutaneous lesions that appear after several years of maintenance therapy with hydroxyurea."1.30Early cutaneous lesions secondary to hydroxyurea therapy. ( Calori, R; Faccini, P; Maiolo, AT; Radaelli, F, 1998)
"Hydroxyurea is an effective agent in the treatment of chronic myelogenous leukemia."1.25Skin changes secondary to hydroxyurea therapy. ( Goltz, RW; Kennedy, BJ; Smith, LR, 1975)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19902 (10.53)18.7374
1990's4 (21.05)18.2507
2000's8 (42.11)29.6817
2010's5 (26.32)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Quattrone, F1
Dini, V1
Barbanera, S1
Zerbinati, N1
Romanelli, M1
Matthews, AG1
Wylie, G1
Girot, R1
Stankovic, K1
Lionnet, F1
Latagliata, R1
Spadea, A1
Cedrone, M1
Di Giandomenico, J1
De Muro, M1
Villivà, N1
Breccia, M1
Anaclerico, B1
Porrini, R1
Spirito, F1
Rago, A1
Avvisati, G1
Alimena, G2
Montanaro, M1
Andriani, A1
Serrano-Falcón, C1
Pugnaire, MAF1
Del Mar Serrano-Falcón, M1
Morales, MG1
Serrano-Ortega, S1
Antonioli, E1
Guglielmelli, P1
Pieri, L1
Finazzi, M1
Rumi, E1
Martinelli, V1
Vianelli, N1
Luigia Randi, M1
Bertozzi, I1
De Stefano, V1
Za, T1
Rossi, E1
Ruggeri, M1
Elli, E1
Cacciola, R1
Cacciola, E1
Pogliani, E1
Rodeghiero, F1
Baccarani, M1
Passamonti, F1
Finazzi, G1
Rambaldi, A1
Bosi, A1
Cazzola, M1
Barbui, T1
Vannucchi, AM1
Bravo Blanco, AM1
Moral, JL1
Tembrás, S1
Gómez, R1
Ulibarrena, C1
Obdulia Vazquez, M1
Yokota, K1
Tasaka, T1
Iwata, K1
Ogawa, H1
Nakano, M1
Seki, K1
Ogura, S1
Geraminejad, PA1
Walling, HW1
Swick, BL1
Sontheimer, RD1
Sanchez-Palacios, C1
Guitart, J1
Bohn, J1
Hansen, JP1
Menné, T1
Radaelli, F1
Calori, R1
Faccini, P1
Maiolo, AT1
Ravandi-Kashani, F1
Cortes, J1
Cohen, P1
Talpaz, M1
O'Brien, S1
Markowitz, A1
Kantarjian, H1
McLintock, C1
Ockelford, PA1
Hachulla, E1
Rose, C1
Trillot, N1
Caulier-Leleu, MT1
Pasturel-Michon, U1
Olesen, LH1
Pedersen, BB1
Kennedy, BJ1
Smith, LR1
Goltz, RW1
Renfro, L1
Kamino, H1
Raphael, B1
Moy, J1
Sanchez, M1
Montefusco, E1
Gastaldi, R1
Carlesimo, OA1
Valesini, G1
Mandelli, F1

Reviews

4 reviews available for hydroxyurea and Skin Ulcer

ArticleYear
Cutaneous ulcers associated with hydroxyurea therapy.
    Journal of tissue viability, 2013, Volume: 22, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Female; Humans; Hydroxyurea; Male; Middle Age

2013
[New issues in adult sickle sell disease].
    Bulletin de l'Academie nationale de medecine, 2008, Volume: 192, Issue:7

    Topics: Adult; Anemia, Sickle Cell; Blood Transfusion; Cardiomyopathies; Combined Modality Therapy; Female;

2008
Hydroxyurea-associated squamous dysplasia.
    Journal of the American Academy of Dermatology, 2004, Volume: 51, Issue:2

    Topics: Aged; Carcinoma, Squamous Cell; Humans; Hydroxyurea; Keratosis; Male; Precancerous Conditions; Skin

2004
[What vascular events suggest a myeloproliferative disorder?].
    Journal des maladies vasculaires, 2000, Volume: 25, Issue:5

    Topics: Adult; Aged; Alkylating Agents; Arterial Occlusive Diseases; Cross-Sectional Studies; Erythromelalgi

2000

Other Studies

15 other studies available for hydroxyurea and Skin Ulcer

ArticleYear
Hydroxycarbamide-induced cutaneous ulceration with a difference.
    The British journal of dermatology, 2014, Volume: 171, Issue:6

    Topics: Diagnosis, Differential; Drug Eruptions; Female; Hematinics; Humans; Hydroxyurea; Middle Aged; Prima

2014
Symptomatic mucocutaneous toxicity of hydroxyurea in Philadelphia chromosome-negative myeloproliferative neoplasms: the Mister Hyde face of a safe drug.
    Cancer, 2012, Jan-15, Volume: 118, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Female; Humans; Hydroxyurea; Male; Middle Age

2012
Toxicoderma caused by hydroxyurea.
    International journal of dermatology, 2011, Volume: 50, Issue:11

    Topics: Aged; Drug Eruptions; Female; Humans; Hydroxyurea; Nail Diseases; Pigmentation Disorders; Skin Ulcer

2011
Hydroxyurea-related toxicity in 3,411 patients with Ph'-negative MPN.
    American journal of hematology, 2012, Volume: 87, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites; Carcinoma, Squamous Cell; Drug Eruptions; Female; F

2012
Hydroxyurea-induced skin ulcerations in patients with chronic myeloproliferative disorders.
    Journal of hematotherapy & stem cell research, 2003, Volume: 12, Issue:4

    Topics: Aged; DNA; Enzyme Inhibitors; Female; Humans; Hydroxyurea; Leg Ulcer; Male; Middle Aged; Myeloprolif

2003
Huge post-operative ulcer following hydroxyurea therapy in a patient with polycythemia vera.
    Haematologica, 2003, Volume: 88, Issue:12

    Topics: Aged; Anti-Bacterial Agents; Busulfan; Combined Modality Therapy; Debridement; Female; Heparin; Hern

2003
Chronic penile ulceration in a 72-year-old man.
    Archives of dermatology, 2004, Volume: 140, Issue:7

    Topics: Aged; Antineoplastic Agents; Chronic Disease; Diagnosis, Differential; Drug Eruptions; Hand Dermatos

2004
Ulcerative lichen planus-like dermatitis due to long-term hydroxyurea therapy.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 1998, Volume: 10, Issue:2

    Topics: Aged; Antineoplastic Agents; Biopsy, Needle; Diagnosis, Differential; Foot Dermatoses; Humans; Hydro

1998
Early cutaneous lesions secondary to hydroxyurea therapy.
    American journal of hematology, 1998, Volume: 58, Issue:1

    Topics: Aged; Humans; Hydroxyurea; Male; Skin Ulcer; Thrombocytosis; Time Factors

1998
Cutaneous ulcers associated with hydroxyurea therapy in myeloproliferative disorders.
    Leukemia & lymphoma, 1999, Volume: 35, Issue:1-2

    Topics: Adult; Aged; Antineoplastic Agents; Female; Humans; Hydroxyurea; Male; Middle Aged; Myeloproliferati

1999
Hydroxyurea induced skin ulceration in myeloproliferative disorders.
    Australian and New Zealand journal of medicine, 2000, Volume: 30, Issue:3

    Topics: Aged; Female; Humans; Hydroxyurea; Male; Middle Aged; Myeloproliferative Disorders; Nucleic Acid Syn

2000
[Hydroxyurea-induced leg ulcers in patients with chronic myeloproliferative disorders].
    Ugeskrift for laeger, 2001, Dec-03, Volume: 163, Issue:49

    Topics: Aged; Antineoplastic Agents; Drug Eruptions; Female; Humans; Hydroxyurea; Leg Ulcer; Leukemia, Myelo

2001
Skin changes secondary to hydroxyurea therapy.
    Archives of dermatology, 1975, Volume: 111, Issue:2

    Topics: Administration, Oral; Adult; Biopsy; Female; Humans; Hydroxyurea; Leukemia, Myeloid; Leukocyte Count

1975
Ulcerative lichen planus-like dermatitis associated with hydroxyurea.
    Journal of the American Academy of Dermatology, 1991, Volume: 24, Issue:1

    Topics: Drug Eruptions; Female; Hand Dermatoses; Humans; Hydroxyurea; Leukemia, Myelogenous, Chronic, BCR-AB

1991
Unusual dermatologic toxicity of long-term therapy with hydroxyurea in chronic myelogenous leukemia.
    Tumori, 1986, Jun-30, Volume: 72, Issue:3

    Topics: Adult; Aged; Antigen-Antibody Complex; Complement Activating Enzymes; Complement C1q; Complement C3;

1986